-
1
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet P., Dor Y., Herbert J.M., Fukumura D., Brusselmans K., Dewerchin M., Neeman M., Bono F., Abramovitch R., Maxwell P., Koch C.J., Ratcliffe P., Moons L., Jain R.K., Collen D., Keshert E. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998, 394:485-490.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
Koch, C.J.11
Ratcliffe, P.12
Moons, L.13
Jain, R.K.14
Collen, D.15
Keshert, E.16
-
2
-
-
0034088368
-
Oxygen-sensitive membrane transporters in vertebrate red cells
-
Gibson J.S., Cossins A.R., Ellory J.C. Oxygen-sensitive membrane transporters in vertebrate red cells. J. Exp. Biol. 2000, 203:1395-1407.
-
(2000)
J. Exp. Biol.
, vol.203
, pp. 1395-1407
-
-
Gibson, J.S.1
Cossins, A.R.2
Ellory, J.C.3
-
3
-
-
0034176782
-
Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies
-
Brown J.M. Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies. Mol. Med. Today 2000, 6:157-162.
-
(2000)
Mol. Med. Today
, vol.6
, pp. 157-162
-
-
Brown, J.M.1
-
4
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza G.L., Wang G.L. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell. Biol. 1992, 12:5447-5454.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
5
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science 2001, 292:468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
6
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein A.C., Gleadle J.M., McNeill L.A., Hewitson K.S., O'Rourke J., Mole D.R., Mukherji M., Metzen E., Wilson M.I., Dhanda A., Tian Y.M., Masson N., Hamilton D.L., Jaakkola P., Barstead R., Hodgkin J., Maxwell P.H., Pugh C.W., Schofield C.J., Ratcliffe P.J. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001, 107:43-54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
7
-
-
33745141162
-
Oxygen-dependent diseases in the retina: role of hypoxia-inducible factors
-
Arjamaa O., Nikinmaa M. Oxygen-dependent diseases in the retina: role of hypoxia-inducible factors. Exp. Eye Res. 2006, 83:473-483.
-
(2006)
Exp. Eye Res.
, vol.83
, pp. 473-483
-
-
Arjamaa, O.1
Nikinmaa, M.2
-
8
-
-
70350353348
-
Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases
-
Yang J., Ledaki I., Turley H., Gatter K.C., Montero J.C., Li J.L., Harris A.L. Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases. Ann. NY Acad. Sci. 2009, 1177:185-197.
-
(2009)
Ann. NY Acad. Sci.
, vol.1177
, pp. 185-197
-
-
Yang, J.1
Ledaki, I.2
Turley, H.3
Gatter, K.C.4
Montero, J.C.5
Li, J.L.6
Harris, A.L.7
-
9
-
-
73549088729
-
Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth
-
Krieg A.J., Rankin E.B., Chan D., Razorenova O., Fernandez S., Giaccia A.J. Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth. Mol. Cell. Biol. 2010, 30:344-353.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 344-353
-
-
Krieg, A.J.1
Rankin, E.B.2
Chan, D.3
Razorenova, O.4
Fernandez, S.5
Giaccia, A.J.6
-
10
-
-
68449090024
-
Identification and characterization of demethylase JMJD1A as a gene upregulated in the human cellular response to hypoxia
-
Sar A., Ponjevic D., Nguyen M., Box A.H., Demetrick D.J. Identification and characterization of demethylase JMJD1A as a gene upregulated in the human cellular response to hypoxia. Cell Tissue Res. 2009, 337:223-234.
-
(2009)
Cell Tissue Res.
, vol.337
, pp. 223-234
-
-
Sar, A.1
Ponjevic, D.2
Nguyen, M.3
Box, A.H.4
Demetrick, D.J.5
-
11
-
-
61349088682
-
The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF
-
Beyer S., Kristensen M.M., Jensen K.S., Johansen J.V., Staller P. The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF. J. Biol. Chem. 2008, 283:36542-36552.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 36542-36552
-
-
Beyer, S.1
Kristensen, M.M.2
Jensen, K.S.3
Johansen, J.V.4
Staller, P.5
-
12
-
-
77956692764
-
Jumonji domain containing 1A is a novel prognostic marker for colorectal cancer: in vivo identification from hypoxic tumor cells
-
Uemura M., Yamamoto H., Takemasa I., Mimori K., Hemmi H., Mizushima T., Ikeda M., Sekimoto M., Matsuura N., Doki Y., Mori M. Jumonji domain containing 1A is a novel prognostic marker for colorectal cancer: in vivo identification from hypoxic tumor cells. Clin. Cancer Res. 2010, 16:4636-4646.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 4636-4646
-
-
Uemura, M.1
Yamamoto, H.2
Takemasa, I.3
Mimori, K.4
Hemmi, H.5
Mizushima, T.6
Ikeda, M.7
Sekimoto, M.8
Matsuura, N.9
Doki, Y.10
Mori, M.11
-
13
-
-
0345491599
-
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
-
Hu C.J., Wang L.Y., Chodosh L.A., Keith B., Simon M.C. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol. Cell. Biol. 2003, 23:9361-9374.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 9361-9374
-
-
Hu, C.J.1
Wang, L.Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
14
-
-
3242875457
-
IGF-1-induced VEGF and IGFBP-3 secretion correlates with increased HIF-1 alpha expression and activity in retinal pigment epithelial cell line D407
-
Slomiany M.G., Rosenzweig S.A. IGF-1-induced VEGF and IGFBP-3 secretion correlates with increased HIF-1 alpha expression and activity in retinal pigment epithelial cell line D407. Invest. Ophthalmol. Vis. Sci. 2004, 45:2838-2847.
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 2838-2847
-
-
Slomiany, M.G.1
Rosenzweig, S.A.2
-
15
-
-
33748544246
-
Characterization of barrier properties and inducible VEGF expression of several types of retinal pigment epithelium in medium-term culture
-
Geisen P., McColm J.R., King B.M., Hartnett M.E. Characterization of barrier properties and inducible VEGF expression of several types of retinal pigment epithelium in medium-term culture. Curr. Eye Res. 2006, 31:739-748.
-
(2006)
Curr. Eye Res.
, vol.31
, pp. 739-748
-
-
Geisen, P.1
McColm, J.R.2
King, B.M.3
Hartnett, M.E.4
-
16
-
-
34848837972
-
Hypoxia-inducible factor expression in human RPE cells
-
Forooghian F., Razavi R., Timms L. Hypoxia-inducible factor expression in human RPE cells. Br. J. Ophthalmol. 2007, 91:1406-1410.
-
(2007)
Br. J. Ophthalmol.
, vol.91
, pp. 1406-1410
-
-
Forooghian, F.1
Razavi, R.2
Timms, L.3
-
17
-
-
63449103705
-
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
-
Xia X., Lemieux M.E., Li W., Carroll J.S., Brown M., Liu X.S., Kung A.L. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc. Natl. Acad. Sci. USA 2009, 106:4260-4265.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4260-4265
-
-
Xia, X.1
Lemieux, M.E.2
Li, W.3
Carroll, J.S.4
Brown, M.5
Liu, X.S.6
Kung, A.L.7
-
18
-
-
33646138230
-
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor
-
Yamane K., Toumazou C., Tsukada Y., Erdjument-Bromage H., Tempst P., Wong J., Zhang Y. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 2006, 125:483-495.
-
(2006)
Cell
, vol.125
, pp. 483-495
-
-
Yamane, K.1
Toumazou, C.2
Tsukada, Y.3
Erdjument-Bromage, H.4
Tempst, P.5
Wong, J.6
Zhang, Y.7
-
19
-
-
0027197671
-
Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma
-
Kitamura K., Kangawa K., Kawamoto M., Ichiki Y., Nakamura S., Matsuo H., Eto T. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem. Biophys. Res. Commun. 1993, 192:553-560.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.192
, pp. 553-560
-
-
Kitamura, K.1
Kangawa, K.2
Kawamoto, M.3
Ichiki, Y.4
Nakamura, S.5
Matsuo, H.6
Eto, T.7
-
21
-
-
79251588745
-
Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1alpha (HIF-1alpha)
-
Thalhammer A., Bencokova Z., Poole R., Loenarz C., Adam J., O'Flaherty L., Schodel J., Mole D., Giaslakiotis K., Schofield C.J., Hammond E.M., Ratcliffe P.J., Pollard P.J. Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1alpha (HIF-1alpha). PLoS One 2011, 6:e16210.
-
(2011)
PLoS One
, vol.6
-
-
Thalhammer, A.1
Bencokova, Z.2
Poole, R.3
Loenarz, C.4
Adam, J.5
O'Flaherty, L.6
Schodel, J.7
Mole, D.8
Giaslakiotis, K.9
Schofield, C.J.10
Hammond, E.M.11
Ratcliffe, P.J.12
Pollard, P.J.13
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