Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: Involvement of hippocampal plasticity via AKT, CREB and BDNF signaling

Mechanisms of Ageing and Development

Volumn 132, Issue 11-12, 2011, Pages 560-567

  Aguiar Jr , Aderbal S ^a   Castro, Adalberto A ^a   Moreira, Eduardo L ^a   Glaser, Viviane ^a   Santos, Adair R S ^a   Tasca, Carla I ^a   Latini, Alexandra ^a   Prediger, Rui D S ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Aging; BDNF; Glutamate; Hippocampus; Learning and memory; Physical exercise; Synaptic plasticity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; PROTEIN KINASE B;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; ENZYME ACTIVITY; EXERCISE INTENSITY; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; LEARNING; MAZE TEST; MEMORY; MENTAL PERFORMANCE; NERVE CELL PLASTICITY; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN TISSUE LEVEL; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TASK PERFORMANCE; WISTAR RAT;

AGED; AGING; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FEMALE; HIPPOCAMPUS; HUMANS; LEARNING; MEMORY; MUSCLE, SKELETAL; NEURONAL PLASTICITY; PHYSICAL CONDITIONING, ANIMAL; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPATIAL BEHAVIOR;

RATTUS; RATTUS NORVEGICUS;

EID: 84855902010     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2011.09.005     Document Type: Article

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