Pilocarpine prevents age-related spatial learning impairments in rats

Behavioural Brain Research

Volumn 158, Issue 2, 2005, Pages 263-268

  De Mello, Nelson ^a   Souza Junior, Iran Q ^a   Carobrez, Antonio P ^a  

^a Department of Pharmacology   (Brazil)

Author keywords

Aging; Learning; Memory; Pilocarpine; Rat; Water maze

Indexed keywords

MUSCARINIC AGENT; PILOCARPINE;

AGE DISTRIBUTION; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; LEARNING DISORDER; MALE; MAZE TEST; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TREATMENT OUTCOME;

EID: 13444273026     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2004.09.006     Document Type: Article

References (56)

1. M.G. Baxter, K.M. Frick, D.L. Price, S.J. Breckler, A.L. Markowska, and L.K. Gorman Presynaptic markers of cholinergic functions in the rat brain: relationship with age and cognitive status Neuroscience 89 1999 771 780
2. A. Birthelmer, J. Stemmelin, R. Jackisch, and J.C. Cassel Presynaptic modulation of acetylcholine, noradrenaline, and serotonin release in the hippocampus of aged rats with various levels of memory impairments. Brain Res Bull 6606 2003 1 14
3. J.D. Brioni, and J.L. McGaugh Post-training administration of GABAenergic antagonists enhances retention of aversively motivated tasks Psychopharmacol (Berl) 96 1988 505 510
4. D.J. Bucci, D.L. Rosen, and M. Gallagher Effects of age on pilocarpine-induced c-fos expression in rat hippocampus and cortex Neurobiol Aging 19 1998 227 232
5. I. Cantallops, and A. Routtenberg Kainic acid induction of mossy fiber sprouting: dependence on mouse strain Hippocampus 10 2000 269 273
6. A.P. Carobrez, C.C. Schimidt, and T. Lemos Effect of 2-amino-5- phosphonopentanoic acid into the dorsal periaqueductal gray on performance of Pilo-pretreated rats in elevated T-maze Soc Neurosci Abstr 25 2 1999 2135
7. M. Carsrlevitz, E. Engerlhardt, and C.A. Esbérard Maturation of convulsogenic activity induced by leptazol in the albino rat Br J Pharmacol 42 1971 31 42
8. 2+ channel activity in single neurons of hippocampal 'zipper' slices Proc Natl Acad Sci USA 97 2000 4357 4362
9. S. Commins, L. Cunningham, D. Harvey, and D. Walsh Massed but not spaced training impairs memory Behav Brain Res 139 2003 215 223
10. T. Crook, R.T. Bartus, S.H. Ferris, P. Whitehouse, and G.D. Cohen Age-associated memory impairment: proposed diagnostic criteria and measures of clinical change-report of a National Institute of Mental Health work group Dev Neuropsychol 2 1986 261 276
11. N. De-Mello, and A.P. Carobrez Elevated T-maze as an animal model of memory: effects of scopolamine Behav Pharmacol 13 2002 139 148
12. C.A. Erickson, and C.A. Barnes The neurobiology of memory changes in normal aging Exp Gerontol 38 2003 61 69
13. W. Fischer, K.S. Chen, F.H. Gage, and A. Bjorklund Progressive decline in spatial learning and integrity of forebrain cholinergic neurons in rats during aging Neurobiol Aging 13 1992 9 23
14. F.G. Gage, K.S. Chen, G. Buzsaki, and D. Armstrong Experimental approaches to age-related cognitive impairments Neurobiol Aging 9 1988 645 655
15. M. Gallagher, R.D. Burwell, M.H. Kodsi, M. Mckinney, S. Southerland, and L. VEll-Rountree Markers for biogenic amines in the aged rat brain: relationship to decline in spatial learning ability Neurobiol Aging 11 1990 507 514
16. M. Gallagher, M. Burwell, and M. Burchinal Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze Behav Neurosci 107 1993 618 626
17. 2+ -mediated excitability in rat CA1 neurons correlate with changes in radial arm maze teaming Soc Neurosci Abstr 25 1999 888
18. T. van Groen, I. Kadish, and M. Wyss Old rats remember old tricks; memories of the water maze persist for 12 months Behav Brain Res 136 2002 247 255
19. C.P. Heisenberg, J.D. Cooper, J. Berke, and M.V. Sofroniew NMDA potentiates NGF-induced sprouting of septal cholinergic fibres Neuro Report 12 1994 413 416
20. T. Hoh, J. Beiko, F. Boon, S. Weiss, and D. Cain Complex behavioral strategy and reversal learning in the water maze without NMDA receptor-dependent long-term potentiation J Neurosci 19 1999 1 5
21. T. Huzen, F. Woudenberg, and J.L. Slangen The long-term effects of diazepam and pentylenetetrazol on the potentiated startle response Pharmacol Biochem Behav 36 1990 35 38
22. (2+) channel blocker inhibits mossy fiber sprouting and cognitive deficits following Pilo seizures in immature mice Neuroscience 98 2000 647 659
23. D.K. Ingram, E.D. London, and C.L. Goodrick Age and neurochemical correlates of radial maze performance in rats Neurobiol Aging 2 1981 41
24. V.E. Koliatsos, D.L. Price, G.K. Gouras, M.H. Cayouette, L.E. Burton, and J.W. Winslow Highly selective effects of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 on intact and injured basal forebrain magnocellular neurons J Comp Neurol 343 1994 247 262
25. P. Krsek, A. Mikulecká, R. Druga, H. Kubová, Z. Hlinák, and L. Suchomelová Long-term behavioral and morphological consequences of nonconvulsive status epilepticus in rats Epilepsy Behav 5 2004 180 191
26. P.A. Lapchak, D.J. Jenden, and F. Hefti Pharmacological stimulation reveals recombinant human nerve growth factor-induced increases of in vivo hippocampal cholinergic function measured in rats with partial fimbria transections Neuroscience 50 1992 847 856
27. B.A. Linkenhoker, and E.I. Knudsen Incremental training increases the plasticity of the auditory space map in adult barn owls Nature 419 2002 293 296
28. W.H. Meck, R.A. Smith, and C.L. Williams Pre- and postnatal choline supplementation produces long-term facilitation of spatial memory Dev Psychobiol 21 1988 339 353
29. H. Miyagawa, M. Hasegawa, T. Fukuta, M. Amano, K. Yamada, and T. Nabeshima Dissociation of impairment between spatial memory, and motor function and emotional behavior in aged rats Behav Brain Res 91 1998 73 81
30. RG.M. Morris Developments of a water maze procedure for studying spatial learning in the rat J Neurosci Meth. 11 1984 47 60
31. J.K. Morse, S.J. Wiegand, K. Anderson, Y.M. You, N. Cai, and J. Carnahan Brain-derived neurotrophic factor BDNF prevents the degeneration of medial septal cholinergic neurons following fimbria transection J Neurosci 13 1993 4146 4156
32. J.R. Moyer Jr., L.T. Thompson, J.P. Black, and J.F. Disterhoft Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner J Neurophysiol 68 1992 2100 2109
33. G. Mudò, X.H. Jiang, T. Timmusk, M. Bindoni, and N. Belluado Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine Epilepsia 37 1996 198 207
34. S. Nakamura, and T. Ohno Spatial learning impairment in aged rats: comparing between aged basal forebrain lesioned and normal aged rats Behav Brain Res 70 1995 69 76
35. M.M. Nicolle, P.J. Colombo, M. Gallagher, and M. McKinney Metabotropic glutamate receptormediated hippocampal phosphoinositide turnover is blunted in spatial learning-impaired aged rats J Neurosci 19 1999 9604 9610
36. M.M. Oh, A.E. Gamelli, W.W. Wu, E. Sametsky, and J.F. Disterhoft Morris water maze learning enhances neuronal excitability of CA1 hippocampal pyramidal neurons in rats Soc Neurosci Abstr 27 2001 1
37. M. Paroczai, B. Kiss, and E. Karpati Effect of RGH-2716 on learning and memory deficits of young and aged rats in water-labyrinth Brain Res Bull 45 1998 475 488
38. H. Parthasarathy Plasticity and the older owl Nature 419 2002 258 259
39. H.M. de Paula, and K. Hoshino Potentiation of panic-like behaviors of the rat by subconvulsive doses of strychnine Physiol Behav 80 4 2004 459 464
40. S. Rahner-Welsch, L. Frölich, S. Stoll, and S. Hoyer Decline and preservation of reversal learning abilities and acquisition in the course of senescence Neursoci Lett 194 1995 121 123
41. D. Saar, Y. Grossman, and E. Barkai Reduced after-hyperpolarization in rat piriform cortex pyramidal neurons is associated with increased learning capability during operant conditioning Eur J Neurosci 10 1998 1518 1523
42. R. Sankar, D.H. Shin, H. Liu, A. Mazarati, A. Pereira Vasconcelos, and C.G. Wasterlain Patterns of status epilepticus-induced neuronal injury during development and long-term consequences J Neurosci 18 1998 8382 8393
43. N.F. Santos, R.M. Arida, E.M. Trindade-Filho, M.R. Priel, and E.A. Cavalheiro Epileptogenesis in immature rats following recurrent status epilepticus Brain Res Rev 32 2000 269 276
44. R. Smith, M.K. Kistler, M. Cohen-Williams, and V.L. Coffin Cholinergic improvement of a naturally-occurring memory deficit in the young rat Brain Res Rev 707 1996 13 21
45. J. Stemmelin, J.C. Cassel, B. Will, and C. Kelch Sensitivity to cholinergic drug treatments of aged rats with variable degrees of spatial memory impairment Behav Brain Res 98 1999 53 66
46. J. Stemmelin, C. Lazarus, S. Cassel, C. Kelche, and J.C. Cassel Immunohistochemical and neurochemical correlates of learning deficits in aged rats Neuroscience 96 2000 275 289
47. L.T. Thompson, and J. Disterhoft Age- and dose-dependent facilitation of associative eyeblink conditioning by d-cycloserine in rabbits Behav Neurosci 111 1997 1303 1312
48. W.A. Turski, S.J. Czuczwart, Z. Kleinrock, and L. Turski Cholinomimetics produce seizures and brain damage Experientia 30 1983 1408 1411
49. W.A. Turski, E.A. Cavalheiro, C. Ikonomidou, L.E. Mello, Z.A. Bortolotto, and L. Turski Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: morphological and electroencephalographic correlates Brain Res 30 361 1985 309 323
50. W.A. Turski, E.A. Cavalheiro, C. Coimbra, M. da Penha Berzaghi, C. Ikonomidou-Turski, and L. Turski Only certain antiepileptic drugs prevent seizures induced by pilocarpine Brain Res 434 3 1987 281 305
51. J.L. Venero, B. Knusel, K.D. Beck, and F. Hefti Expression of neurotrophin and trk receptor genes in adult rats with fimbria transections: effect of intraventricular nerve growth factor and brain-derived neurotrophic factor administration Neuroscience 59 1994 797 815
52. J.S. Villarreal, F. Gonzalez-Lima, J. Berndt, and E.J. Barea-Rodriguez Water maze training in aged rats: effects on brain metabolic capacity behavior Brain Res 939 2002 43 51
53. C. Weiss, A.R. Preston, M.M. Oh, R.D. Schwarz, D. Welty, and J.F. Disterhoft The M1 muscarinic agonist CI-1017 facilitates trace eyeblink conditioning in aging rabbits and increases the excitability of CA1 pyramidal neurons J Neurosci 20 2000 783 790
54. I.Q. Whishaw Dissociating performance and learning deficits on spatial navigation tasks in rats subjected to cholinergic muscarinic blockade Brain Res Bull 23 1989 358 374
55. C. Wu, L. Huang, C. Liou, T. Wang, Y. Tung, and H. Hsu Lithium-Pilocarpine-induced status epilepticus in immature rats results in long-term deficits in spatial learning and hippocampal cell loss Neurosci Lett 312 2001 113 117
56. W.W. Wu, M.M. Oh, and J.F. Disterhoft Age-related biophysical alterations of hippocampal pyramidal neurons: implications for learning and memory Aging Res Rev. 1 2002 181 207