메뉴 건너뛰기




Volumn 79, Issue 1, 2012, Pages 11-17

Prolyl hydroxylase domain 2 protein is a strong prognostic marker in human gastric cancer

Author keywords

Angiogenesis; EGL nine homolog 1; Gastric cancer; Hypoxia inducible factor; Prolyl hydroxylase domain 2 protein

Indexed keywords

BIOLOGICAL MARKER; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE DOMAIN 2 PROTEIN; UNCLASSIFIED DRUG;

EID: 84855882979     PISSN: 10152008     EISSN: 14230291     Source Type: Journal    
DOI: 10.1159/000330170     Document Type: Article
Times cited : (12)

References (29)
  • 1
    • 19944430507 scopus 로고    scopus 로고
    • Trends in the inci-dence of gastric cancer in Japan and the as-sociations with Helicobacter pylori infection and gastric mucosal atrophy
    • Kobayashi T, Kikuchi S, Lin Y, Yagyu K Obata Y, Ogihara A, et al: Trends in the inci-dence of gastric cancer in Japan and the as-sociations with Helicobacter pylori infection and gastric mucosal atrophy. Gastric Cancer 2004; 7: 233-239.
    • (2004) Gastric Cancer , vol.7 , pp. 233-239
    • Kobayashi, T.1    Kikuchi, S.2    Lin, Y.3    Yagyu Obata, K.Y.4    Ogihara, A.5
  • 3
    • 0037586420 scopus 로고    scopus 로고
    • Gastric Cancer: Epidemiology, pathology and treatment
    • Alberts SR, Cervantes A, van de Velde CJ: Gastric Cancer: epidemiology, pathology and treatment. Ann Oncol 2003; 14: 2:31-36.
    • (2003) Ann Oncol , vol.14 , Issue.2 , pp. 31-36
    • Alberts, S.R.1    Cervantes, A.2    Van De Velde, C.J.3
  • 4
    • 77952982353 scopus 로고    scopus 로고
    • The role of surgery in the treatment of gastric cancer
    • Shi Y, Zhou Y: The role of surgery in the treatment of gastric cancer. J Surg Oncol 2010; 101:687-692.
    • (2010) J Surg Oncol , vol.101 , pp. 687-692
    • Shi, Y.1    Zhou, Y.2
  • 5
    • 77749252149 scopus 로고    scopus 로고
    • Sur-gery for gastric cancer: An evidence-based perspective
    • D'souza MA, Singh K, Shrikhande SV: Sur-gery for gastric cancer: an evidence-based perspective. J Can Res Ther 2009; 5:225-231.
    • (2009) J Can Res Ther , vol.5 , pp. 225-231
    • D'Souza, M.A.1    Singh, K.2    Shrikhande, S.V.3
  • 6
    • 48249141410 scopus 로고    scopus 로고
    • D2 lymph-adenectomy alone or with para-aortic nodal dissection for gastric cancer
    • Sasako M, Sano T, Yamamoto S, Kurokawa Y, Nashimoto A, Kurita A, et al: D2 lymph-adenectomy alone or with para-aortic nodal dissection for gastric cancer. N Engl J Med 2008; 359:453-462.
    • (2008) N Engl J Med , vol.359 , pp. 453-462
    • Sasako, M.1    Sano, T.2    Yamamoto, S.3    Kurokawa, Y.4    Nashimoto, A.5    Kurita, A.6
  • 7
    • 67349217696 scopus 로고    scopus 로고
    • Laparoscopic versus open subtotal gastrectomy for adenocarci-noma: A case-control study
    • Strong VE, Devaud N, Allen PJ, Gonen M, Brennan MF, Coit D: Laparoscopic versus open subtotal gastrectomy for adenocarci-noma: a case-control study. Ann Surg Oncol 2009; 16:1507-1513.
    • (2009) Ann Surg Oncol , vol.16 , pp. 1507-1513
    • Strong, V.E.1    Devaud, N.2    Allen, P.J.3    Gonen, M.4    Brennan, M.F.5    Coit, D.6
  • 8
    • 40949114950 scopus 로고    scopus 로고
    • Role and regulation of prolyl hydroxylase domain proteins
    • DOI 10.1038/cdd.2008.10, PII CDD200810, The biology of Hypoxia-inducible factors
    • Fong GH, Takeda K: Role and regulation of prolyl hydroxylase domain proteins. Cell Death Differ 2008; 15:635-641. (Pubitemid 351405066)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.4 , pp. 635-641
    • Fong, G.-H.1    Takeda, K.2
  • 9
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • DOI 10.1126/science.1066373
    • Bruick RK, McKnight SL: A conserved fam-ily of prolyl-4-hydroxylases that modify HIF. Science 2001; 294:1337-1340. (Pubitemid 33063099)
    • (2001) Science , vol.294 , Issue.5545 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 10
    • 0041465022 scopus 로고    scopus 로고
    • HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia
    • DOI 10.1093/emboj/cdg392
    • Berra E, Benizri E, Ginouves A, Volmat V, Roux D, Pouyssegur J: HIF prolyl-hydroxy-lase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia. EMBO J 2003; 22:4082-4090. (Pubitemid 37021737)
    • (2003) EMBO Journal , vol.22 , Issue.16 , pp. 4082-4090
    • Berra, E.1    Benizri, E.2    Ginouves, A.3    Volmat, V.4    Roux, D.5    Pouyssegur, J.6
  • 11
    • 0033571682 scopus 로고    scopus 로고
    • Overexpres-sion of hypoxia-inducible factor 1α in com-mon human cancers and their metastases
    • Zhong H, De Marzo AM, Laughner E, Lim M, Hilton DA, Zagzag D, et al: Overexpres-sion of hypoxia-inducible factor 1α in com-mon human cancers and their metastases. Cancer Res 1999; 59: 5830-5835.
    • (1999) Cancer Res , vol.59 , pp. 5830-5835
    • Zhong, H.1    De Marzo, A.M.2    Laughner, E.3    Lim, M.4    Hilton, D.A.5    Zagzag, D.6
  • 12
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • Semenza GL: HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med 2002; 8: 62-67.
    • (2002) Trends Mol Med , vol.8 , pp. 62-67
    • Semenza, G.L.1
  • 13
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other disease
    • Carmeliet P, Jain RK: Angiogenesis in cancer and other disease. Nature 2000; 407:249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 14
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL: Targeting HIF-1 for cancer therapy. Nature 2003; 3:721-731.
    • (2003) Nature , vol.3 , pp. 721-731
    • Semenza, G.L.1
  • 15
    • 51049097730 scopus 로고    scopus 로고
    • The biphasic role of the hypoxia-inducible factor prolyl-4-hy-droxylase, PHD2, in modulating tumor-forming potential
    • Lee KA, Lynd JD, O'Reilly S, Kiupel M, Mc-Cormick JJ, LaPres JJ: The biphasic role of the hypoxia-inducible factor prolyl-4-hy-droxylase, PHD2, in modulating tumor-forming potential. Mol Cancer Res 2008; 6: 829-842.
    • (2008) Mol Cancer Res , vol.6 , pp. 829-842
    • Lee, K.A.1    Lynd, J.D.2    O'Reilly, S.3    Kiupel, M.4    Mc-Cormick, J.J.5    Lapres, J.J.6
  • 16
    • 31444442758 scopus 로고    scopus 로고
    • Induction of human endometrial cancer cell senescence through modulation of HIF-1α activity by EGLN1
    • DOI 10.1002/ijc.21488
    • Kato H, Inoue T, Asanoma K, Nishimura C, Matsuda T, Wake N: Induction of human en-dometrial cancer cell senescence through modulation of HIF-1α activity by EGLN1. Int J Cancer 2006; 118:1144-1153. (Pubitemid 43185600)
    • (2006) International Journal of Cancer , vol.118 , Issue.5 , pp. 1144-1153
    • Kato, H.1    Inoue, T.2    Asanoma, K.3    Nishimura, C.4    Matsuda, T.5    Wake, N.6
  • 17
    • 65649138377 scopus 로고    scopus 로고
    • Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment
    • Chan DA, Kawahara TL, Sutphin PD, Chang HY, Chi JT, Giaccia AJ: Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer Cell 2009; 15: 527-538.
    • (2009) Cancer Cell , vol.15 , pp. 527-538
    • Chan, D.A.1    Kawahara, T.L.2    Sutphin, P.D.3    Chang, H.Y.4    Chi, J.T.5    Giaccia, A.J.6
  • 18
    • 77954175077 scopus 로고    scopus 로고
    • PHD2 in tumor angio-genesis
    • Chan DA, Giaccia AJ: PHD2 in tumor angio-genesis. Br J Cancer 2010; 1:1-5.
    • (2010) Br J Cancer , vol.1 , pp. 1-5
    • Chan, D.A.1    Giaccia, A.J.2
  • 19
    • 77958540773 scopus 로고    scopus 로고
    • Prolyl hydroxy-lase domain (PHD) 2 affects cell migration and F-actin formation RhoA/rho-associated kinase-dependent cofilin phosphorylation
    • Vogel S, Wottawa M, Farhat K, Zieseniss A, Schnelle M, Lee-Huu S, et al: Prolyl hydroxy-lase domain (PHD) 2 affects cell migration and F-actin formation RhoA/rho-associated kinase-dependent cofilin phosphorylation. J Biol Chem 2010; 285:33756-33763.
    • (2010) J Biol Chem , vol.285 , pp. 33756-33763
    • Vogel, S.1    Wottawa, M.2    Farhat, K.3    Zieseniss, A.4    Schnelle, M.5    Lee-Huu, S.6
  • 20
    • 33644781737 scopus 로고    scopus 로고
    • Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness
    • DOI 10.1158/1078-0432.CCR-05-2022
    • Jokilehto T, Rantanen K, Luukkaa M, Heik-kinen P, Grenman R, Minn H, et al: Overex-pression and nuclear translocation of hypox-ia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness. Clin Cancer Res 2006; 12:1080-1087. (Pubitemid 43342495)
    • (2006) Clinical Cancer Research , vol.12 , Issue.4 , pp. 1080-1087
    • Jokilehto, T.1    Rantanen, K.2    Luukkaa, M.3    Heikkinen, P.4    Grenman, R.5    Minn, H.6    Kronqvist, P.7    Jaakkola, P.M.8
  • 21
    • 38549157208 scopus 로고    scopus 로고
    • Association of pat-terns of class i histone deacetylase expres-sion with patient prognosis in gastric cancer: A retrospective analysis
    • Weichert W, Röske A, Gekeler V, Beckers T, Ebert MP, Pross M, et al: Association of pat-terns of class I histone deacetylase expres-sion with patient prognosis in gastric cancer: a retrospective analysis. Lancet Oncol 2008; 9: 139-148.
    • (2008) Lancet Oncol , vol.9 , pp. 139-148
    • Weichert, W.1    Röske, A.2    Gekeler, V.3    Beckers, T.4    Ebert, M.P.5    Pross, M.6
  • 23
    • 67449155921 scopus 로고    scopus 로고
    • A new target for tumor therapy
    • Jain RK: A New Target for Tumor Therapy. N Engl J Med 2009; 360: 269-271.
    • (2009) N Engl J Med , vol.360 , pp. 269-271
    • Jain, R.K.1
  • 24
    • 77953495380 scopus 로고    scopus 로고
    • Apicidin upreg-ulates PHD2 prolyl hydroxylase gene expres-sion in cervical cancer cells
    • Durczak M, Jagodzinski PP: Apicidin upreg-ulates PHD2 prolyl hydroxylase gene expres-sion in cervical cancer cells. Anti Cancer Drugs 2010; 21:619-624.
    • (2010) Anti Cancer Drugs , vol.21 , pp. 619-624
    • Durczak, M.1    Jagodzinski, P.P.2
  • 25
    • 42949106526 scopus 로고    scopus 로고
    • Rapid degradation of hypoxia-inducible factor-1α by KRH102053, a new activator of prolyl hydroxylase 2
    • DOI 10.1038/bjp.2008.70, PII BJP200870
    • Choi HJ, Song BJ, Gong YD, Gwak WJ, Soh Y: Rapid degradation of hypoxia-inducible factor-1α by KRH102053, a new activator of prolyl hydroxylase 2. Br J Pharmacol 2008; 154:114-125. (Pubitemid 351620399)
    • (2008) British Journal of Pharmacology , vol.154 , Issue.1 , pp. 114-125
    • Choi, H.J.1    Song, B.-J.2    Gong, Y.-D.3    Gwak, W.J.4    Soh, Y.5
  • 26
    • 33847737677 scopus 로고    scopus 로고
    • Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1α in human melanoma cells
    • DOI 10.1158/0008-5472.CAN-06-2606
    • Spinella F, Rosano L, Di Castro V, Decandia S, Nicotra MR, Natali PG, et al: Endothelin-1 and endothelin-3 promote invasive behav-iour via hypoxia-inducible factor-1α in hu-man melanoma cells. Cancer Res 2007; 67: 1725-1734. (Pubitemid 46383399)
    • (2007) Cancer Research , vol.67 , Issue.4 , pp. 1725-1734
    • Spinella, F.1    Rosano, L.2    Di Castro, V.3    Decandia, S.4    Nicotra, M.R.5    Natali, P.G.6    Bagnato, A.7
  • 27
    • 77955289816 scopus 로고    scopus 로고
    • Endothelin-1 inhibits prolyl hydroxylase domain 2 to acti-vate hypoxia-inducible factor-1α in melano-ma cells
    • Spinella F, Rosano L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, et al: Endothelin-1 inhibits prolyl hydroxylase domain 2 to acti-vate hypoxia-inducible factor-1α in melano-ma cells. PLoS 2010; 5:e11241.
    • (2010) PLoS , vol.5
    • Spinella, F.1    Rosano, L.2    Del Duca, M.3    Di Castro, V.4    Nicotra, M.R.5    Natali, P.G.6
  • 29
    • 59649117924 scopus 로고    scopus 로고
    • Hetero-zygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via en-dothelial normalization
    • Mazzone M, Dettori D, Leite de Oliveira R, Loges S, Schmidt T, Jonckx B, et al: Hetero-zygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via en-dothelial normalization. Cell 2009; 136: 839-851.
    • (2009) Cell , vol.136 , pp. 839-851
    • Mazzone, M.1    Dettori, D.2    Leite De Oliveira, R.3    Loges, S.4    Schmidt, T.5    Jonckx, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.