메뉴 건너뛰기




Volumn 415, Issue 2, 2011, Pages 215-219

RhoA co-ordinates with heterotrimeric G proteins to regulate efficacy

Author keywords

G proteins; GPCRs; GTPases; Phosphatidic acid; Phospholipase C ; Phospholipase D; RhoA

Indexed keywords

DIACYLGLYCEROL KINASE; G PROTEIN COUPLED RECEPTOR; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDIC ACID; PHOSPHOLIPASE C BETA1; PHOSPHOLIPASE C BETA2; PHOSPHOLIPASE C BETA3; PHOSPHOLIPASE C BETA4; PHOSPHOLIPASE C GAMMA1; PHOSPHOLIPASE D1; PROTEIN KINASE C; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84855865226     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.10.063     Document Type: Short Survey
Times cited : (4)

References (43)
  • 1
    • 0023062991 scopus 로고
    • G proteins: transducers of receptor-generated signals
    • Gilman A.G. G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 1987, 56:615-649.
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 2
    • 33947407279 scopus 로고    scopus 로고
    • Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 α subunits plus βγ dimers
    • Birnbaumer L. Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 α subunits plus βγ dimers. Biochim. Biophys. Acta 2007, 1784:772-793.
    • (2007) Biochim. Biophys. Acta , vol.1784 , pp. 772-793
    • Birnbaumer, L.1
  • 3
    • 79952014987 scopus 로고    scopus 로고
    • GPCRs, G-proteins, effectors and their interactions: human-gpDB, a database employing visualization tools and data integration techniques, Database (Oxford). Aug 5
    • V. P. Satagopam, M. C. Theodoropoulou, C. K. Stampolakis, G. A. Pavlopoulos, N. C. Papandreou, P. G. Bagos, R. Schneider, S. J. Hamodrakas, GPCRs, G-proteins, effectors and their interactions: human-gpDB, a database employing visualization tools and data integration techniques, Database (Oxford). Aug 5 2010.
    • (2010)
    • Satagopam, V.P.1    Theodoropoulou, M.C.2    Stampolakis, C.K.3    Pavlopoulos, G.A.4    Papandreou, N.C.5    Bagos, P.G.6    Schneider, R.7    Hamodrakas, S.J.8
  • 4
    • 34548443356 scopus 로고    scopus 로고
    • Structural basis of effector regulation and signal termination in heterotrimeric Gα proteins
    • Sprang S.R., Chen Z., Du X. Structural basis of effector regulation and signal termination in heterotrimeric Gα proteins. Adv. Protein Chem. 2007, 74:1-65.
    • (2007) Adv. Protein Chem. , vol.74 , pp. 1-65
    • Sprang, S.R.1    Chen, Z.2    Du, X.3
  • 6
    • 79851480014 scopus 로고    scopus 로고
    • q and phospholipase C-β: turn on, turn off, and do it fast
    • q and phospholipase C-β: turn on, turn off, and do it fast. Sci. Signal. 2011, 4:pe5.
    • (2011) Sci. Signal. , vol.4
    • Ross, E.M.1
  • 7
    • 79960671811 scopus 로고    scopus 로고
    • Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets
    • Kimple A.J., Bosch D.E., Giguère P.M., Siderovski D.P. Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets. Pharmacol. Rev. 2011, 63:728-749.
    • (2011) Pharmacol. Rev. , vol.63 , pp. 728-749
    • Kimple, A.J.1    Bosch, D.E.2    Giguère, P.M.3    Siderovski, D.P.4
  • 8
    • 50849086372 scopus 로고    scopus 로고
    • Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP
    • Turcotte M., Ross E.M. Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP. PLoS Comput. Biol. 2008, 8:e1000148.
    • (2008) PLoS Comput. Biol. , vol.8
    • Turcotte, M.1    Ross, E.M.2
  • 9
    • 0036878206 scopus 로고    scopus 로고
    • Novel mechanisms for feedback regulation of phospholipase C-β activity
    • Litosch I. Novel mechanisms for feedback regulation of phospholipase C-β activity. IUBMB Life 2002, 53:253-260.
    • (2002) IUBMB Life , vol.53 , pp. 253-260
    • Litosch, I.1
  • 11
    • 84855895351 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases: More than just kinases and not only for GPCRs, Pharmacol. Ther. (Epub ahead of print)
    • E. V. Gurevich, J. J. Tesmer, A. Mushegian, V. V. Gurevich, G protein-coupled receptor kinases: More than just kinases and not only for GPCRs, Pharmacol. Ther. 2011. (Epub ahead of print).
    • (2011)
    • Gurevich, E.V.1    Tesmer, J.J.2    Mushegian, A.3    Gurevich, V.V.4
  • 12
    • 80052038573 scopus 로고    scopus 로고
    • β-arrestin-mediated receptor trafficking and signal transduction
    • Shenoy S.K., Lefkowitz R.J. β-arrestin-mediated receptor trafficking and signal transduction. Trends Pharmacol. Sci. 2011, 32:521-533.
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 521-533
    • Shenoy, S.K.1    Lefkowitz, R.J.2
  • 13
    • 77952354490 scopus 로고    scopus 로고
    • Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery
    • Kenakin T., Miller L.J. Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery. Pharmacol. Rev. 2010, 62:265-304.
    • (2010) Pharmacol. Rev. , vol.62 , pp. 265-304
    • Kenakin, T.1    Miller, L.J.2
  • 15
    • 33646200560 scopus 로고    scopus 로고
    • Gβγ inhibits Gα GTPase-activating proteins by inhibition of Gα-GTP binding during stimulation by receptor
    • Tang W., Tu Y., Nayak S.K., Woodson J., Jehl M., Ross E.M. Gβγ inhibits Gα GTPase-activating proteins by inhibition of Gα-GTP binding during stimulation by receptor. J. Biol. Chem. 2006, 281:4746-4753.
    • (2006) J. Biol. Chem. , vol.281 , pp. 4746-4753
    • Tang, W.1    Tu, Y.2    Nayak, S.K.3    Woodson, J.4    Jehl, M.5    Ross, E.M.6
  • 16
    • 0027214868 scopus 로고
    • Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C β by G protein α and βγ subunits
    • Smrcka A.V., Sternweis P.C. Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C β by G protein α and βγ subunits. J. Biol. Chem. 1993, 268:9667-9674.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9667-9674
    • Smrcka, A.V.1    Sternweis, P.C.2
  • 19
    • 4344600505 scopus 로고    scopus 로고
    • Allosteric regulation of GAP activity by phospholipids in regulators of G-protein signaling
    • Tu Y., Wilkie T.M. Allosteric regulation of GAP activity by phospholipids in regulators of G-protein signaling. Methods Enzymol. 2004, 389:89-105.
    • (2004) Methods Enzymol. , vol.389 , pp. 89-105
    • Tu, Y.1    Wilkie, T.M.2
  • 21
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: biochemistry and biology
    • Jaffe A.B., Hall A. Rho GTPases: biochemistry and biology. Annu. Rev. Cell Dev. Biol. 2005, 21:247-269.
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 22
    • 74549193568 scopus 로고    scopus 로고
    • Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors
    • Aittaleb M., Boguth C.A., Tesmer J.J. Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors. Mol. Pharmacol. 2010, 77:111-125.
    • (2010) Mol. Pharmacol. , vol.77 , pp. 111-125
    • Aittaleb, M.1    Boguth, C.A.2    Tesmer, J.J.3
  • 24
    • 23644455714 scopus 로고    scopus 로고
    • Phospholipase D: a lipid centric review
    • M Jenkins G., Frohman M.A. Phospholipase D: a lipid centric review. Cell. Mol. Life Sci. 2005, 62:2305-2316.
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 2305-2316
    • M Jenkins, G.1    Frohman, M.A.2
  • 26
    • 68949151730 scopus 로고    scopus 로고
    • Emerging findings from studies of phospholipase D in model organisms (and a short update on phosphatidic acid effectors)
    • Raghu P., Manifava M., Coadwell J., Ktistakis N.T. Emerging findings from studies of phospholipase D in model organisms (and a short update on phosphatidic acid effectors). Biochim. Biophys. Acta 2009, 1791:889-897.
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 889-897
    • Raghu, P.1    Manifava, M.2    Coadwell, J.3    Ktistakis, N.T.4
  • 27
    • 33748300590 scopus 로고    scopus 로고
    • Phosphatidic acid- and phosphatidylserine-binding proteins
    • Stace C.L., Ktistakis N.T. Phosphatidic acid- and phosphatidylserine-binding proteins. Biochim. Biophys. Acta 2006, 1761:913-926.
    • (2006) Biochim. Biophys. Acta , vol.1761 , pp. 913-926
    • Stace, C.L.1    Ktistakis, N.T.2
  • 28
    • 78149273391 scopus 로고    scopus 로고
    • Heterogeneity of phosphatidic acid levels and distribution at the plasma membrane in living cells as visualized by a Föster resonance energy transfer (FRET) biosensor
    • Nishioka T., Frohman M.A., Matsuda M., Kiyokawa E. Heterogeneity of phosphatidic acid levels and distribution at the plasma membrane in living cells as visualized by a Föster resonance energy transfer (FRET) biosensor. J. Biol. Chem. 2010, 285:35979-35987.
    • (2010) J. Biol. Chem. , vol.285 , pp. 35979-35987
    • Nishioka, T.1    Frohman, M.A.2    Matsuda, M.3    Kiyokawa, E.4
  • 29
    • 2342520613 scopus 로고    scopus 로고
    • LIPID arrays: new tools in the understanding of membrane dynamics and lipid signaling
    • Ivanova P.T., Milne S.B., Forrester J.S., Brown H.A. LIPID arrays: new tools in the understanding of membrane dynamics and lipid signaling. Mol. Interv. 2004, 4:86-96.
    • (2004) Mol. Interv. , vol.4 , pp. 86-96
    • Ivanova, P.T.1    Milne, S.B.2    Forrester, J.S.3    Brown, H.A.4
  • 30
    • 79551613763 scopus 로고    scopus 로고
    • PLC regulation: emerging pictures for molecular mechanisms
    • Bunney T.D., Katan M. PLC regulation: emerging pictures for molecular mechanisms. Trends Biochem. Sci. 2011, 36:88-96.
    • (2011) Trends Biochem. Sci. , vol.36 , pp. 88-96
    • Bunney, T.D.1    Katan, M.2
  • 36
    • 0037452494 scopus 로고    scopus 로고
    • Regulation of phospholipase C-β activity by phosphatidic acid: isoform dependence role of protein kinase C and G protein subunits
    • Litosch I. Regulation of phospholipase C-β activity by phosphatidic acid: isoform dependence role of protein kinase C and G protein subunits. Biochemistry 2003, 42:1618-1623.
    • (2003) Biochemistry , vol.42 , pp. 1618-1623
    • Litosch, I.1
  • 38
    • 54849409470 scopus 로고    scopus 로고
    • 1 in telencephalic principal neurons cerebellar interneurons and its close association with related signaling molecules in somatodendritic neuronal elements
    • 1 in telencephalic principal neurons cerebellar interneurons and its close association with related signaling molecules in somatodendritic neuronal elements. Eur. J. Neurosci. 2008, 28:1744-1759.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 1744-1759
    • Fukaya, M.1    Uchigashima, M.2    Nomura, S.3    Hasegawa, Y.4    Kikuchi, H.5    Watanabe, M.6
  • 42
    • 33748495796 scopus 로고    scopus 로고
    • Activation of phospholipase Cε by free fatty acids and cross talk with phospholipase D and phospholipase A2
    • Murthy S.N., Chung P.H., Lin L., Lomasney J.W. Activation of phospholipase Cε by free fatty acids and cross talk with phospholipase D and phospholipase A2. Biochemistry 2006, 45:10987-10997.
    • (2006) Biochemistry , vol.45 , pp. 10987-10997
    • Murthy, S.N.1    Chung, P.H.2    Lin, L.3    Lomasney, J.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.