Synergistic Ca2+ responses by Gαi- and Gαq-coupled G-protein-coupled receptors require a single PLCβ isoform that is sensitive to both Gβγ and Gαq

Journal of Biological Chemistry

Volumn 286, Issue 2, 2011, Pages 942-951

  Rebres, Robert A ^a   Roach, Tamara I A ^a   Fraser, Iain D C ^b   Philip, Finly ^c   Moon, Christina ^a   Lin, Keng Mean ^c   Liu, Jamie ^b   Santat, Leah ^b   Cheadle, Lucas ^b   Ross, Elliott M ^c   Simon, Melvin I ^a   Seaman, William E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CELL TYPES; COUPLED RECEPTORS; G PROTEIN COUPLED RECEPTORS; IN-CELL; ISOFORMS; OVER-EXPRESSION; PHOSPHOLIPASE C;

MACROPHAGES; PROTEINS;

CALCIUM;

CALCIUM ION; COMPLEMENT COMPONENT C5A; G ALPHA I PROTEIN COUPLED RECEPTOR; G ALPHA Q PROTEIN COUPLED RECEPTOR; G BETA GAMMA PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR; PHOSPHOLIPASE C; PHOSPHOLIPASE C BETA1; PHOSPHOLIPASE C BETA2; PHOSPHOLIPASE C BETA3; PHOSPHOLIPASE C BETA4; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; PHOSPHOLIPASE C BETA; PLCB1 PROTEIN, MOUSE; PLCB2 PROTEIN, MOUSE; PLCB3 PROTEIN, HUMAN; PLCB3 PROTEIN, MOUSE; PLCB4 PROTEIN, MOUSE; PURINERGIC P2 RECEPTOR; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL STRAIN 3T3; CELL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME REGULATION; GENE MUTATION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; 129 MOUSE; ANIMAL; C57BL MOUSE; CALCIUM SIGNALING; GENETICS; MACROPHAGE; METABOLISM; MUTAGENESIS; PHYSIOLOGY;

ANIMALS; CALCIUM SIGNALING; COMPLEMENT C5A; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HUMANS; MACROPHAGES; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MUTAGENESIS; NIH 3T3 CELLS; PHOSPHOLIPASE C BETA; RECEPTORS, PURINERGIC P2; RNA, SMALL INTERFERING; URIDINE DIPHOSPHATE;

EID: 78651392392     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.198200     Document Type: Article

References (52)

1. Berridge, M. J., Bootman, M. D., and Roderick, H. L. (2003) Nat. Rev. Mol. Cell Biol. 4, 517-529
2. Berridge, M. J. (2006) Cell Calcium 40, 405-412
3. Delmas, P., Crest, M., and Brown, D. A. (2004) Trends Neurosci. 27, 41-47
4. Okajima, F., Sato, K., Sho, K., and Kondo, Y. (1989) FEBS Lett. 248, 145-149
5. Werry, T. D., Wilkinson, G. F., and Willars, G. B. (2003) Biochem. J. 374, 281-296
6. Dickenson, J. M., and Hill, S. J. (1993) Biochem. Soc Trans. 21, 1124-1129
7. Jiménez, A. I., Castro, E., Mirabet, M., Franco, R., Delicado, E. G., and Miras-Portugal, M. T. (1999) Glia 26, 119-128
8. Toms, N. J., and Roberts, P. J. (1999) Neuropharmacology 38, 1511-1517
9. Shah, B. H., Siddiqui, A., Qureshi, K. A., Khan, M., Rafi, S., Ujan, V. A., Yaqub, Y., Rasheed, H., and Saeed, S. A. (1999) Exp. Mol. Med. 31, 42-46
10. Carroll, R. C., Morielli, A. D., and Peralta, E. G. (1995) Curr. Biol. 5, 536-544
11. Roach, T. I., Rebres, R. A., Fraser, I. D., Decamp, D. L., Lin, K. M., Sternweis, P. C., Simon, M. I., and Seaman, W. E. (2008) J. Biol. Chem. 283, 17351-17361
12. Dickenson, J. M., and Hill, S. J. (1994) Int. J. Biochem. 26, 959-969
13. Cilluffo, M. C., Esqueda, E., and Farahbakhsh, N. A. (2000) Am. J. Physiol. Cell Physiol. 279, C734-C743
14. Okajima, F., Tomura, H., and Kondo, Y. (1993) Biochem. J. 290, 241-247
15. Dickenson, J. M., and Hill, S. J. (1996) Eur. J. Pharmacol. 302, 141-151
16. Werry, T. D., Wilkinson, G. F., and Willars, G. B. (2003) J. Pharmacol. Exp. Ther. 307, 661-669
17. Smrcka, A. V., and Sternweis, P. C. (1993) J. Biol. Chem. 268, 9667-9674
18. Park, D., Jhon, D. Y., Lee, C. W., Lee, K. H., and Rhee, S. G. (1993) J. Biol. Chem. 268, 4573-4576
19. Lee, C. W., Lee, K. H., Lee, S. B., Park, D., and Rhee, S. G. (1994) J. Biol. Chem. 269, 25335-25338
20. Camps, M., Carozzi, A., Schnabel, P., Scheer, A., Parker, P. J., and Gierschik, P. (1992) Nature 360, 684-686
21. Quitterer, U., and Lohse, M. J. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 10626-10631
22. Xie, W., Samoriski, G. M., McLaughlin, J. P., Romoser, V. A., Smrcka, A., Hinkle, P. M., Bidlack, J. M., Gross, R. A., Jiang, H., and Wu, D. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 10385-10390
23. Jiang, H., Kuang, Y., Wu, Y., Xie, W., Simon, M. I., and Wu, D. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 7971-7975
24. Coward, P., Wada, H. G., Falk, M. S., Chan, S. D., Meng, F., Akil, H., and Conklin, B. R. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 352-357
25. Wu, J., Cherwinski, H., Spies, T., Phillips, J. H., and Lanier, L. L. (2000) J. Exp. Med. 192, 1059-1068
26. Zavzavadjian, J. R., Couture, S., Park, W. S., Whalen, J., Lyon, S., Lee, G., Fung, E., Mi, Q., Liu, J., Wall, E., Santat, L., Dhandapani, K., Kivork, C., Driver, A., Zhu, X., Chang, M. S., Randhawa, B., Gehrig, E., Bryan, H., Verghese, M., Maer, A., Saunders, B., Ning, Y., Subramaniam, S., Meyer, T., Simon, M. I., O'Rourke, N., Chandy, G., and Fraser, I. D. (2007) Mol. Cell Proteomics 6, 413-424
27. Rhee, S. G. (2001) Annu. Rev. Biochem. 70, 281-312
28. Ilkaeva, O., Kinch, L. N., Paulssen, R. H., and Ross, E. M. (2002) J. Biol. Chem. 277, 4294-4300
29. Kim, C. G., Park, D., and Rhee, S. G. (1996) J. Biol. Chem. 271, 21187-21192
30. Bonacci, T. M., Ghosh, M., Malik, S., and Smrcka, A. V. (2005) J. Biol. Chem. 280, 10174-10181
31. Sankaran, B., Osterhout, J., Wu, D., and Smrcka, A. V. (1998) J. Biol. Chem. 273, 7148-7154
32. Swift, S., Lorens, J., Achacoso, P., and Nolan, G. P. (2001) Curr. Protoc. Immunol., Chapter 10, Unit 10.17C
33. Morita, S., Kojima, T., and Kitamura, T. (2000) Gene Ther. 7, 1063-1066
34. Biddlecome, G. H., Berstein, G., and Ross, E. M. (1996) J. Biol. Chem. 271, 7999-8007
35. Wang, T., Dowal, L., El-Maghrabi, M. R., Rebecchi, M., and Scarlata, S. (2000) J. Biol. Chem. 275, 7466-7469
36. Watson, A. J., Katz, A., and Simon, M. I. (1994) J. Biol. Chem. 269, 22150-22156
37. Wu, D., Katz, A., and Simon, M. I. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 5297-5301
38. Rebecchi, M. J., and Pentyala, S. N. (2000) Physiol. Rev. 80, 1291-1335
39. Boyer, J. L., Graber, S. G., Waldo, G. L., Harden, T. K., and Garrison, J. C. (1994) J. Biol. Chem. 269, 2814-2819
40. Ueda, N., Iñiguez-Lluhi, J. A., Lee, E., Smrcka, A. V., Robishaw, J. D., and Gilman, A. G. (1994) J. Biol. Chem. 269, 4388-4395
41. Park, D., Jhon, D. Y., Lee, C. W., Ryu, S. H., and Rhee, S. G. (1993) J. Biol. Chem. 268, 3710-3714
42. Wu, D., Jiang, H., Katz, A., and Simon, M. I. (1993) J. Biol. Chem. 268, 3704-3709
43. Wang, T., Pentyala, S., Elliott, J. T., Dowal, L., Gupta, E., Rebecchi, M. J., and Scarlata, S. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 7843-7846
44. Lee, S. B., Shin, S. H., Hepler, J. R., Gilman, A. G., and Rhee, S. G. (1993) J. Biol. Chem. 268, 25952-25957
45. Sternweis, P. C., and Smrcka, A. V. (1993) Ciba Found. Symp. 176, 96-106; discussion 106-111
46. Jhon, D. Y., Lee, H. H., Park, D., Lee, C. W., Lee, K. H., Yoo, O. J., and Rhee, S. G. (1993) J. Biol. Chem. 268, 6654-6661
47. Philip, F., Kadamur, G., Silos, R. G., Woodson, J., and Ross, E. M. (2010) Curr. Biol. 20, 1327-1335
48. Ranganathan, R., and Ross, E. M. (1997) Curr. Biol. 7, R770-773
49. Suh, P. G., Hwang, J. I., Ryu, S. H., Donowitz, M., and Kim, J. H. (2001) Biochem. Biophys. Res. Commun. 288, 1-7
50. Fam, S. R., Paquet, M., Castleberry, A. M., Oller, H., Lee, C. J., Traynelis, S. F., Smith, Y., Yun, C. C., and Hall, R. A. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 8042-8047
51. Hwang, J. I., Kim, H. S., Lee, J. R., Kim, E., Ryu, S. H., and Suh, P. G. (2005) J. Biol. Chem. 280, 12467-12473
52. Grynkiewicz, G., Poenie, M., and Tsien, R. Y. (1985) J. Biol. Chem. 260, 3440-3450