Serum oxidative stress-induced repression of NrF2 and GSH depletion: A mechanism potentially involved in endothelial dysfunction of young smokers

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Pasini, Anna Fratta ^a   Albiero, Anna ^a   Stranieri, Chiara ^a   Cominacini, Mattia ^a   Pasini, Andrea ^a   Mozzini, Chiara ^a   Vallerio, Paola ^a   Cominacini, Luciano ^a   Garbin, Ulisse ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 PALMITOYL 2 ARACHIDONYL 3 PHOSPHORYLCHOLINE; 1-PALMITOYL-2-ARACHIDONYL-3-PHOSPHORYLCHOLINE; BIOLOGICAL MARKER; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE 1; LIPOPROTEIN; NITRIC OXIDE; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID 1 PALMITOYL 2 ARACHIDONYL SN GLYCERO 3 PHOSPHORYLCHOLINE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; ARTICLE; BLOOD; CATALYSIS; CELL CULTURE; CELL FUNCTION; CIGARETTE SMOKING; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVE SITE; ENZYME REPRESSION; FEMALE; GENETICS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; METABOLISM; MONONUCLEAR CELL; NORMAL HUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PHARMACOLOGY; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SERUM; SIGNAL TRANSDUCTION; SMOKING; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; VASODILATATION; WESTERN BLOTTING;

ADULT; BLOOD; BLOTTING, WESTERN; CATALYTIC DOMAIN; CELLS, CULTURED; CULTURE MEDIA; DRUG EFFECTS; ENDOTHELIUM, VASCULAR; FEMALE; GENETICS; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE-1; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPOPROTEINS; MALE; METABOLISM; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHARMACOLOGY; PHOSPHATIDYLCHOLINES; PHYSIOPATHOLOGY; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SERUM; SMOKING; YOUNG ADULT;

EID: 84855857730     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030291     Document Type: Article

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