Nitric oxide-mediated protection of endothelial cells from hydrogen peroxide is mediated by intracellular zinc and glutathione

American Journal of Physiology - Cell Physiology

Volumn 296, Issue 4, 2009, Pages

  Cortese Krott, Miriam M ^a,b   Suschek, Christoph V ^b   Wetzel, Wiebke ^c   Kröncke, Klaus Dietrich ^a   Kolb Bachofen, Victoria ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c Institute of Biochemistry and Molecular Biology II   (Germany)

Author keywords

Glutamate cysteine ligase; Inducible nitric oxide synthase; Nrf2; Oxidative stress; Zinc signaling

Indexed keywords

ANTIOXIDANT; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; NITRIC OXIDE; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MTF 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ZINC;

AMINO ACID CELL LEVEL; ANIMAL CELL; ARTICLE; CELL LEVEL; CELL PROTECTION; CHELATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVE SITE; GENE EXPRESSION; GENE EXPRESSION REGULATION; INFLAMMATION; LASER MICROSCOPY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SYNTHESIS; TRANSCRIPTION INITIATION; ZINC CELL LEVEL;

ANIMALS; CELL SURVIVAL; CHELATING AGENTS; CYTOPROTECTION; ENDOTHELIAL CELLS; ETHYLAMINES; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MALE; NF-E2-RELATED FACTOR 2; NITRIC OXIDE; NITRIC OXIDE DONORS; OXIDANTS; OXIDATIVE STRESS; PYRIMIDINES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TIME FACTORS; TRIAZENES; ZINC;

RATTUS;

EID: 65649150412     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00643.2008     Document Type: Article

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