Cigarette smoking blocks the protective expression of Nrf2/ARE pathway in peripheral mononuclear cells of young heavy smokers favouring inflammation

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Garbin, Ulisse ^a   Pasini, Anna Fratta ^a   Stranieri, Chiara ^a   Cominacini, Mattia ^a   Pasini, Andrea ^a   Manfro, Stefania ^a   Lugoboni, Fabio ^b   Mozzini, Chiara ^a   Guidi, GianCesare ^a   Faccini, Giovanni ^a   Cominacini, Luciano ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b G B ROSSI UNIVERSITY HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOLIPID; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; ANTIOXIDANT; BIOLOGICAL MARKER; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; I KAPPA B; INTERLEUKIN 6; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NFE2L2 PROTEIN, HUMAN; OXIDIZED L ALPHA 1 PALMITOYL 2 ARACHIDONOYL SN GLYCERO 3 PHOSPHORYLCHOLINE; OXIDIZED-L-ALPHA-1-PALMITOYL-2-ARACHIDONOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE; PHOSPHATIDYLCHOLINE;

ADULT; ARTICLE; ATHEROSCLEROSIS; CIGARETTE SMOKING; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; MALE; NORMAL HUMAN; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; VOLUNTEER; ADOLESCENT; BLOOD; BLOOD DONOR; CELL PROTECTION; DNA RESPONSIVE ELEMENT; ENZYMOLOGY; GENETICS; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; SMOKING;

ADOLESCENT; ADULT; ANTIOXIDANTS; BIOLOGICAL MARKERS; BLOOD DONORS; CYTOPROTECTION; ENZYME ACTIVATION; FEMALE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE-1; HUMANS; I-KAPPA B PROTEINS; INFLAMMATION; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MALE; NADPH OXIDASE; NF-E2-RELATED FACTOR 2; NF-KAPPA B; PHOSPHATIDYLCHOLINES; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS; SMOKING; YOUNG ADULT;

EID: 77949517866     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008225     Document Type: Article

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