DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation

DNA Repair

Volumn 11, Issue 2, 2012, Pages 177-184

  Jung, Yong Sam ^a   Qian, Yingjuan ^a   Chen, Xinbin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

E3 ligase; Mdm2; PolH; Ubiquitination; UV

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DNA DIRECTED DNA POLYMERASE ETA; PROTEIN MDM2; PROTEIN P53;

ARTICLE; CONTROLLED STUDY; ENZYME DEGRADATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UBIQUITINATION; ULTRAVIOLET IRRADIATION;

CELL DEATH; CELL LINE; CELL SURVIVAL; DNA-DIRECTED DNA POLYMERASE; GENE KNOCKDOWN TECHNIQUES; HUMANS; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MDM2; UBIQUITINATION; ULTRAVIOLET RAYS;

EID: 84855850825     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2011.10.017     Document Type: Article

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