Alternative splicing regulates Kv3.1 polarized targeting to adjust maximal spiking frequency

Journal of Biological Chemistry

Volumn 287, Issue 3, 2012, Pages 1755-1769

  Gu, Yuanzheng ^a   Barry, Joshua ^a   McDougel, Robert ^a   Terman, David ^a   Gu, Chen ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTION POTENTIALS; ALTERNATIVE SPLICING; BIOPHYSICAL PROPERTIES; CHANNEL BLOCKERS; DIGITAL OUTPUT; ELECTROSTATIC REPULSION; FIRING FREQUENCY; HIPPOCAMPAL NEURONS; INPUT-OUTPUT; NEURONAL FIRINGS; SPLICE VARIANTS; SYNAPTIC INPUT;

COMPUTER SIMULATION; ELECTROPHYSIOLOGY; POTASSIUM;

FREQUENCY RESPONSE;

POTASSIUM CHANNEL KV1.2; POTASSIUM CHANNEL KV3.1; POTASSIUM CHANNEL KV3.1A; POTASSIUM CHANNEL KV3.1B; POTASSIUM CHANNEL KV4.2; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CARBOXY TERMINAL SEQUENCE; COMPUTER SIMULATION; CONTROLLED STUDY; DENDRITE; DEPOLARIZATION; HIPPOCAMPUS; MUTAGENESIS; NERVE CELL CULTURE; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE EXCITABILITY; NERVE FIBER; NONHUMAN; POINT MUTATION; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN TARGETING; RAT; SEQUENCE ALIGNMENT; SPIKE WAVE; SPIKING FREQUENCY; SYNAPTIC POTENTIAL;

ALTERNATIVE SPLICING; ANIMALS; AXONS; DENDRITES; HEK293 CELLS; HIPPOCAMPUS; HUMANS; MUTAGENESIS; NERVE TISSUE PROTEINS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RATS; SHAW POTASSIUM CHANNELS;

EID: 84855841410     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.299305     Document Type: Article

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