A novel targeting signal for proximal clustering of the Kv2.1 K+ channel in hippocampal neurons

Neuron

Volumn 25, Issue 2, 2000, Pages 385-397

  Lim, Seung T ^a   Antonucci, Dana E ^a   Scannevin, Robert H ^a   Trimmer, James S ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHIMERA; CYTOPLASM; DENDRITE; GENE DELETION; HIPPOCAMPUS; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION;

EID: 0033757858     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80902-2     Document Type: Article

References (53)

1. Rat hippocampal neurons in dispersed cell culture
2. Delayed rectifier currents in rat globus pallidus neurons are attributable to Kv2.1 and Kv3.1/3.2 K(+) channels
3. Generation and characterization of subtype-specific monoclonal antibodies to K+ channel α- and β-subunit polypeptides
4. Localization of postsynapfic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A
5. Voltage-gated potassium channel genes
6. The internalization signal and the phosphorylation site of transferrin receptor are distinct from the main basolateral sorting information
7. Intracellular routing of wild-type and mutated polymeric immunoglobulin receptor in hippocampal neurons in culture
8. Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture
9. + channel, Kv2.1, is apposed to astrocytic processes and is associated with inhibitory postsynaptic membranes in hippocampal and cortical principal neurons and inhibitory interneurons
10. Molecular diversity of Kv α and β subunits expression in canine gastrointestinal smooth muscles
11. Release and sequestration of calcium by ryanodine-sensifive stores in rat hippocampal neurones
12. Rat hippocampal neurons in low-density culture
13. Synapfic PDZ domaincontaining proteins
14. Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits
15. + channel regulation of signal propagation in dendrites of hippocampal pyramidal cells
16. Localization of TGN38 to the trans-Golgi network: Involvement of a cytoplasmic tyrosine-containing sequence
17. + channels of the Shab subfamily
18. The polarized sorting of membrane proteins expressed in cultured hippocampal neurons using viral vectors
19. Post-Golgi biosynthetic trafficking
20. Organization and regulation of proteins at synapses
21. Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases
22. Calcium-containing organelles display unique reactivity to chemical stimulation in cultured hippocampal neurons
23. Ultrastructural localization of Shaker-related potassium channel subunits and synapse-associated protein 90 to septate-like junctions in rat cerabellar Pinceaux
24. Determination of the subunit stoichiometry of a voltage-activated potassium channel
25. Differential spatiotemporal expression of K+ channel polypeptides in rat hippocampal neurons developing in situ and in vitro
26. Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein
27. SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo
28. Identification of the Kv2.1 K+ channel as a major component of the delayed rectifier K+ current in rat hippocampal neurons
29. Phosphorylation of the Kv2.1 K+ channel alters voltage-dependent activation
30. Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits
31. The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts
32. Voltage-gated potassium channels: From hyperexcitability to excitement
33. Association and colocalization of K+ channel α- and β-subunit polypeptides in rat brain
34. Association and colocalization of Kvb1.1 and Kvb2 with Kv1 α subunits in mammalian brain K+ channel complexes
35. Identification of a cytoplasmic domain important in the polarized expression and clustering of the Kv2.1 K+ channel
36. Subunit combinations defined for K+ channel Kv1 subtypes in synaptic membranes from bovine brain
37. + channels in PC12 cells
38. Glutamate receptor anchoring proteins and the molecular organization of excitatory synapses
39. Properties of Kv2.1 K+ channels expressed in transfected mammalian cells
40. Beta subunits promote K+ channel surface expression through effects early in biosynthesis
41. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains
42. Axon/dendrite targeting of metabotropic glutamate receptors by their cytoplasmic carboxyterminal domains
43. Action potential initiation and backpropagation in neurons of the mammalian CNS
44. Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain
45. Essential role for dlg in synaptic clustering of Shaker K+ channels in vivo
46. Synaptic clustering of the cell adhesion molecule Fasciclin II by Discs-large and its role in the regulation of presynaptic structure
47. Immunological identification and characterization of a delayed rectifier K+ channel polypeptide in rat brain
48. Regulation of ion channel expression by cytoplasmic subunits
49. Sorting out receptor trafficking
50. Alteration and restoration of K+ channel function by deletions at the N- and C-termini
51. Identification of a somatodendritic targeting signal in the cytoplasmic domain of the transferrin receptor
52. Synaptic clustering of Fascilin II and Shaker: Essential targeting sequences and role of Dlg