-
1
-
-
0038509089
-
Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group
-
Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol 2003;121:749-57.
-
(2003)
Br J Haematol
, vol.121
, pp. 749-757
-
-
-
2
-
-
8944220233
-
A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome
-
Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996;335:91-7.
-
(1996)
N Engl J Med
, vol.335
, pp. 91-97
-
-
Attal, M.1
Harousseau, J.L.2
Stoppa, A.M.3
-
3
-
-
0012689130
-
Impact on survival of high-dose therapy with autologous stem cell support in patients younger than 60years with newly diagnosed multiple myeloma: a population-based study. Nordic Myeloma Study Group
-
Lenhoff S, Hjorth M, Holmberg E, et al. Impact on survival of high-dose therapy with autologous stem cell support in patients younger than 60years with newly diagnosed multiple myeloma: a population-based study. Nordic Myeloma Study Group. Blood 2000;95:7-11.
-
(2000)
Blood
, vol.95
, pp. 7-11
-
-
Lenhoff, S.1
Hjorth, M.2
Holmberg, E.3
-
4
-
-
33645812337
-
Impact of age on survival after intensive therapy for multiple myeloma: a population-based study by the Nordic Myeloma Study Group
-
Lenhoff S, Hjorth M, Westin J, et al. Impact of age on survival after intensive therapy for multiple myeloma: a population-based study by the Nordic Myeloma Study Group. Br J Haematol 2006;133:389-96.
-
(2006)
Br J Haematol
, vol.133
, pp. 389-396
-
-
Lenhoff, S.1
Hjorth, M.2
Westin, J.3
-
5
-
-
37449025229
-
Cyclophosphamide plus dexamethasone is an efficient initial treatment before high-dose melphalan and autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: results of a randomized comparison with vincristine, doxorubicin, and dexamethasone
-
Mellqvist UH, Lenhoff S, Johnsen HE, Hjorth M, Holmberg E, Juliusson G, Tangen JM, Westin J. Cyclophosphamide plus dexamethasone is an efficient initial treatment before high-dose melphalan and autologous stem cell transplantation in patients with newly diagnosed multiple myeloma: results of a randomized comparison with vincristine, doxorubicin, and dexamethasone. Cancer 2008;112:129-35.
-
(2008)
Cancer
, vol.112
, pp. 129-135
-
-
Mellqvist, U.H.1
Lenhoff, S.2
Johnsen, H.E.3
Hjorth, M.4
Holmberg, E.5
Juliusson, G.6
Tangen, J.M.7
Westin, J.8
-
6
-
-
34249945940
-
Patterns of survival in multiple myeloma: a population-based study of patients diagnosed in Sweden from 1973 to 2003
-
Kristinsson SY, Landgren O, Dickman PW, Derolf AR, Bjorkholm M. Patterns of survival in multiple myeloma: a population-based study of patients diagnosed in Sweden from 1973 to 2003. J Clin Oncol 2007;25:1993-9.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1993-1999
-
-
Kristinsson, S.Y.1
Landgren, O.2
Dickman, P.W.3
Derolf, A.R.4
Bjorkholm, M.5
-
7
-
-
41949114641
-
Recent major improvement in long-term survival of younger patients with multiple myeloma
-
Brenner H, Gondos A, Pulte D. Recent major improvement in long-term survival of younger patients with multiple myeloma. Blood 2008;111:2521-6.
-
(2008)
Blood
, vol.111
, pp. 2521-2526
-
-
Brenner, H.1
Gondos, A.2
Pulte, D.3
-
8
-
-
41949130070
-
Improved survival in multiple myeloma and the impact of novel therapies
-
Kumar SK, Rajkumar SV, Dispenzieri A, et al. Improved survival in multiple myeloma and the impact of novel therapies. Blood 2007;111:2516-20.
-
(2007)
Blood
, vol.111
, pp. 2516-2520
-
-
Kumar, S.K.1
Rajkumar, S.V.2
Dispenzieri, A.3
-
9
-
-
67650726486
-
Multiple myeloma
-
Raab MS, Podar K, Breitkreutz I, Richardson PG, Anderson KC. Multiple myeloma. Lancet 2009;374:324-39.
-
(2009)
Lancet
, vol.374
, pp. 324-339
-
-
Raab, M.S.1
Podar, K.2
Breitkreutz, I.3
Richardson, P.G.4
Anderson, K.C.5
-
10
-
-
62549132481
-
Treatment of newly diagnosed myeloma
-
Palumbo A, Rajkumar SV. Treatment of newly diagnosed myeloma. Leukemia 2009;23:449-56.
-
(2009)
Leukemia
, vol.23
, pp. 449-456
-
-
Palumbo, A.1
Rajkumar, S.V.2
-
11
-
-
77950421708
-
Melphalan 200mg/m(2) versus melphalan 100mg/m(2) in newly diagnosed myeloma patients: a prospective, multicenter phase 3 study
-
Palumbo A, Bringhen S, Bruno B, et al. Melphalan 200mg/m(2) versus melphalan 100mg/m(2) in newly diagnosed myeloma patients: a prospective, multicenter phase 3 study. Blood 2010;115:1873-9.
-
(2010)
Blood
, vol.115
, pp. 1873-1879
-
-
Palumbo, A.1
Bringhen, S.2
Bruno, B.3
-
12
-
-
33748778465
-
Intensive therapy for multiple myeloma in patients younger than 60years. Long-term results focusing on the effect of the degree of response on survival and relapse pattern after transplantation
-
Lenhoff S, Hjorth M, Turesson I, et al. Intensive therapy for multiple myeloma in patients younger than 60years. Long-term results focusing on the effect of the degree of response on survival and relapse pattern after transplantation. Haematologica 2006;91:1228-33.
-
(2006)
Haematologica
, vol.91
, pp. 1228-1233
-
-
Lenhoff, S.1
Hjorth, M.2
Turesson, I.3
-
13
-
-
77955832716
-
Improved survival of multiple myeloma patients with late relapse after high-dose treatment and stem cell support, a population-based study of 348 patients in Denmark in 1994-2004
-
Vangsted AJ, Klausen TW, Andersen NF, Abildgaard N, Gang AO, Gregersen H, Vogel U, Gimsing P. Improved survival of multiple myeloma patients with late relapse after high-dose treatment and stem cell support, a population-based study of 348 patients in Denmark in 1994-2004. Eur J Haematol 2010;85:209-16.
-
(2010)
Eur J Haematol
, vol.85
, pp. 209-216
-
-
Vangsted, A.J.1
Klausen, T.W.2
Andersen, N.F.3
Abildgaard, N.4
Gang, A.O.5
Gregersen, H.6
Vogel, U.7
Gimsing, P.8
-
14
-
-
51649083847
-
First thalidomide clinical trial in multiple myeloma: a decade
-
van RF, Dhodapkar M, Shaughnessy JD Jr, et al. First thalidomide clinical trial in multiple myeloma: a decade. Blood 2008;112:1035-8.
-
(2008)
Blood
, vol.112
, pp. 1035-1038
-
-
van, R.F.1
Dhodapkar, M.2
Shaughnessy Jr., J.D.3
-
15
-
-
33845518467
-
Bortezomib appears to overcome the poor prognosis conferred by chromosome 13 deletion in phase 2 and 3 trials
-
Jagannath S, Richardson PG, Sonneveld P, Schuster MW, Irwin D, Stadtmauer EA, Facon T, Harousseau JL, Cowan JM, Anderson KC. Bortezomib appears to overcome the poor prognosis conferred by chromosome 13 deletion in phase 2 and 3 trials. Leukemia 2007;21:151-7.
-
(2007)
Leukemia
, vol.21
, pp. 151-157
-
-
Jagannath, S.1
Richardson, P.G.2
Sonneveld, P.3
Schuster, M.W.4
Irwin, D.5
Stadtmauer, E.A.6
Facon, T.7
Harousseau, J.L.8
Cowan, J.M.9
Anderson, K.C.10
-
16
-
-
78049501226
-
Bortezomib plus dexamethasone induction improves outcome of patients with t(4;14) myeloma but not outcome of patients with del(17p)
-
Avet-Loiseau H, Leleu X, Roussel M, et al. Bortezomib plus dexamethasone induction improves outcome of patients with t(4;14) myeloma but not outcome of patients with del(17p). J Clin Oncol 2010;28:4630-4.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4630-4634
-
-
Avet-Loiseau, H.1
Leleu, X.2
Roussel, M.3
-
17
-
-
34248347478
-
The pharmacogenetics of CYP2C9 and CYP2C19: ethnic variation and clinical significance
-
Rosemary J, Adithan C. The pharmacogenetics of CYP2C9 and CYP2C19: ethnic variation and clinical significance. Curr Clin Pharmacol 2007;2:93-109.
-
(2007)
Curr Clin Pharmacol
, vol.2
, pp. 93-109
-
-
Rosemary, J.1
Adithan, C.2
-
18
-
-
58149339953
-
Clinical pharmacogenetics and potential application in personalized medicine
-
Zhou SF, Di YM, Chan E, et al. Clinical pharmacogenetics and potential application in personalized medicine. Curr Drug Metab 2008;9:738-84.
-
(2008)
Curr Drug Metab
, vol.9
, pp. 738-784
-
-
Zhou, S.F.1
Di, Y.M.2
Chan, E.3
-
20
-
-
32644465703
-
Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19
-
Timm R, Kaiser R, Lotsch J, Heider U, Sezer O, Weisz K, Montemurro M, Roots I, Cascorbi I, et al. Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19. Pharmacogenomics J 2005;5:365-73.
-
(2005)
Pharmacogenomics J
, vol.5
, pp. 365-373
-
-
Timm, R.1
Kaiser, R.2
Lotsch, J.3
Heider, U.4
Sezer, O.5
Weisz, K.6
Montemurro, M.7
Roots, I.8
Cascorbi, I.9
-
21
-
-
33947538297
-
Influence of genetic polymorphisms in CYP3A4, CYP3A5, GSTP1, GSTM1, GSTT1 and MDR1 genes on survival and therapy-related toxicity in multiple myeloma
-
Schilthuizen C, Broyl A, van der Holt B, de KY, Lokhorst H, Sonneveld P. Influence of genetic polymorphisms in CYP3A4, CYP3A5, GSTP1, GSTM1, GSTT1 and MDR1 genes on survival and therapy-related toxicity in multiple myeloma. Haematologica 2007;92:277-8.
-
(2007)
Haematologica
, vol.92
, pp. 277-278
-
-
Schilthuizen, C.1
Broyl, A.2
van der Holt, B.3
de, K.Y.4
Lokhorst, H.5
Sonneveld, P.6
-
22
-
-
77955951914
-
No influence of the polymorphisms CYP2C19 and CYP2D6 on the efficacy of cyclophosphamide, thalidomide, and bortezomib in patients with Multiple Myeloma
-
Vangsted AJ, Soeby K, Klausen TW, Abildgaard N, Andersen NF, Gimsing P, Gregersen H, Vogel U, Werge T, Rasmussen HB. No influence of the polymorphisms CYP2C19 and CYP2D6 on the efficacy of cyclophosphamide, thalidomide, and bortezomib in patients with Multiple Myeloma. BMC Cancer 2010;10:404.
-
(2010)
BMC Cancer
, vol.10
, pp. 404
-
-
Vangsted, A.J.1
Soeby, K.2
Klausen, T.W.3
Abildgaard, N.4
Andersen, N.F.5
Gimsing, P.6
Gregersen, H.7
Vogel, U.8
Werge, T.9
Rasmussen, H.B.10
-
23
-
-
77955573688
-
Genetic polymorphisms associated with outcome in multiple myeloma patients receiving high-dose melphalan
-
Dumontet C, Landi S, Reiman T, et al. Genetic polymorphisms associated with outcome in multiple myeloma patients receiving high-dose melphalan. Bone Marrow Transplant 2010;45:1316-24.
-
(2010)
Bone Marrow Transplant
, vol.45
, pp. 1316-1324
-
-
Dumontet, C.1
Landi, S.2
Reiman, T.3
-
24
-
-
0036285336
-
Thalidomide metabolism by the CYP2C subfamily
-
Ando Y, Fuse E, Figg WD. Thalidomide metabolism by the CYP2C subfamily. Clin Cancer Res 2002;8:1964-73.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1964-1973
-
-
Ando, Y.1
Fuse, E.2
Figg, W.D.3
-
25
-
-
0032100604
-
Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent
-
Bauer KS, Dixon SC, Figg WD. Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent. Biochem Pharmacol 1998;55:1827-34.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1827-1834
-
-
Bauer, K.S.1
Dixon, S.C.2
Figg, W.D.3
-
26
-
-
36348965389
-
Polymorphisms of CYP2C19 gene are associated with the efficacy of thalidomide based regimens in multiple myeloma
-
Li Y, Hou J, Jiang H, Wang D, Fu W, Yuan Z, Chen Y, Zhou L. Polymorphisms of CYP2C19 gene are associated with the efficacy of thalidomide based regimens in multiple myeloma. Haematologica 2007;92:1246-9.
-
(2007)
Haematologica
, vol.92
, pp. 1246-1249
-
-
Li, Y.1
Hou, J.2
Jiang, H.3
Wang, D.4
Fu, W.5
Yuan, Z.6
Chen, Y.7
Zhou, L.8
-
27
-
-
70349243697
-
Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells
-
Hideshima T, Ikeda H, Chauhan D, et al. Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells. Blood 2009;114:1046-52.
-
(2009)
Blood
, vol.114
, pp. 1046-1052
-
-
Hideshima, T.1
Ikeda, H.2
Chauhan, D.3
-
28
-
-
18844383217
-
Human metabolism of the proteasome inhibitor bortezomib: identification of circulating metabolites
-
Pekol T, Daniels JS, Labutti J, Parsons I, Nix D, Baronas E, Hsieh F, Gan LS, Miwa G. Human metabolism of the proteasome inhibitor bortezomib: identification of circulating metabolites. Drug Metab Dispos 2005;33:771-7.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 771-777
-
-
Pekol, T.1
Daniels, J.S.2
Labutti, J.3
Parsons, I.4
Nix, D.5
Baronas, E.6
Hsieh, F.7
Gan, L.S.8
Miwa, G.9
-
29
-
-
27544462180
-
Relative contributions of the five major human cytochromes P450, 1A2, 2C9, 2C19, 2D6, and 3A4, to the hepatic metabolism of the proteasome inhibitor bortezomib
-
Uttamsingh V, Lu C, Miwa G, Gan LS. Relative contributions of the five major human cytochromes P450, 1A2, 2C9, 2C19, 2D6, and 3A4, to the hepatic metabolism of the proteasome inhibitor bortezomib. Drug Metab Dispos 2005;33:1723-8.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1723-1728
-
-
Uttamsingh, V.1
Lu, C.2
Miwa, G.3
Gan, L.S.4
-
30
-
-
0029869752
-
Interactions of melphalan with glutathione and the role of glutathione S-transferase
-
Awasthi S, Bajpai KK, Piper JT, et al. Interactions of melphalan with glutathione and the role of glutathione S-transferase. Drug Metab Dispos 1996;24:371-4.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 371-374
-
-
Awasthi, S.1
Bajpai, K.K.2
Piper, J.T.3
-
31
-
-
0141593518
-
Polymorphic variation in GSTP1 modulates outcome following therapy for multiple myeloma
-
Dasgupta RK, Adamson PJ, Davies FE, et al. Polymorphic variation in GSTP1 modulates outcome following therapy for multiple myeloma. Blood 2003;102:2345-50.
-
(2003)
Blood
, vol.102
, pp. 2345-2350
-
-
Dasgupta, R.K.1
Adamson, P.J.2
Davies, F.E.3
-
32
-
-
36048948903
-
Response to chemotherapy and tandem autologous transplantation of multiple myeloma patients and GSTP1 and TYMS polymorphisms
-
Maggini V, Buda G, Galimberti S, et al. Response to chemotherapy and tandem autologous transplantation of multiple myeloma patients and GSTP1 and TYMS polymorphisms. Leuk Res 2008;32:49-53.
-
(2008)
Leuk Res
, vol.32
, pp. 49-53
-
-
Maggini, V.1
Buda, G.2
Galimberti, S.3
-
33
-
-
34548723286
-
Intermediate-dose melphalan compared with myeloablative treatment in multiple myeloma: long-term follow-up of the Dutch Cooperative Group HOVON 24 trial
-
Sonneveld P, van der Holt B, Segeren CM, et al. Intermediate-dose melphalan compared with myeloablative treatment in multiple myeloma: long-term follow-up of the Dutch Cooperative Group HOVON 24 trial. Haematologica 2007;92:928-35.
-
(2007)
Haematologica
, vol.92
, pp. 928-935
-
-
Sonneveld, P.1
van der Holt, B.2
Segeren, C.M.3
-
34
-
-
47349110179
-
Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition
-
Zhou SF. Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition. Xenobiotica 2008;8:802-32.
-
(2008)
Xenobiotica
, vol.8
, pp. 802-832
-
-
Zhou, S.F.1
-
35
-
-
0027507266
-
P-glycoprotein expression in human plasma cell myeloma: correlation with prior chemotherapy
-
Grogan TM, Spier CM, Salmon SE, Matzner M, Rybski J, Weinstein RS, Scheper RJ, Dalton WS. P-glycoprotein expression in human plasma cell myeloma: correlation with prior chemotherapy. Blood 1993;81:490-5.
-
(1993)
Blood
, vol.81
, pp. 490-495
-
-
Grogan, T.M.1
Spier, C.M.2
Salmon, S.E.3
Matzner, M.4
Rybski, J.5
Weinstein, R.S.6
Scheper, R.J.7
Dalton, W.S.8
-
36
-
-
0038323843
-
Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities
-
Morita N, Yasumori T, Nakayama K. Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities. Biochem Pharmacol 2003;65:1843-52.
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 1843-1852
-
-
Morita, N.1
Yasumori, T.2
Nakayama, K.3
-
37
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, Gottesman MM. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 2007;315:525-8.
-
(2007)
Science
, vol.315
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.W.3
Sauna, Z.E.4
Calcagno, A.M.5
Ambudkar, S.V.6
Gottesman, M.M.7
-
38
-
-
33749989048
-
MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells
-
Salama NN, Yang Z, Bui T, Ho RJ. MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells. J Pharm Sci 2006;95:2293-308.
-
(2006)
J Pharm Sci
, vol.95
, pp. 2293-2308
-
-
Salama, N.N.1
Yang, Z.2
Bui, T.3
Ho, R.J.4
-
39
-
-
34247889831
-
MDR1 polymorphism influences the outcome of multiple myeloma patients
-
Buda G, Maggini V, Galimberti S, et al. MDR1 polymorphism influences the outcome of multiple myeloma patients. Br J Haematol 2007;137:454-6.
-
(2007)
Br J Haematol
, vol.137
, pp. 454-456
-
-
Buda, G.1
Maggini, V.2
Galimberti, S.3
-
40
-
-
42149099346
-
MDR1 diplotypes as prognostic markers in multiple myeloma
-
Maggini V, Buda G, Martino A, Presciuttini S, Galimberti S, Orciuolo E, Barale R, Petrini M, Rossi AM. MDR1 diplotypes as prognostic markers in multiple myeloma. Pharmacogenet Genomics 2008;18:383-9.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 383-389
-
-
Maggini, V.1
Buda, G.2
Martino, A.3
Presciuttini, S.4
Galimberti, S.5
Orciuolo, E.6
Barale, R.7
Petrini, M.8
Rossi, A.M.9
-
41
-
-
68449090715
-
ABCB1 (MDR1) rs1045642 is associated with increased overall survival in plasma cell myeloma
-
Drain S, Catherwood MA, Orr N, Galligan L, Rea IM, Hodkinson C, Drake MB, Kettle PJ, Morris TC, Alexander HD. ABCB1 (MDR1) rs1045642 is associated with increased overall survival in plasma cell myeloma. Leuk Lymphoma 2009;50:566-70.
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 566-570
-
-
Drain, S.1
Catherwood, M.A.2
Orr, N.3
Galligan, L.4
Rea, I.M.5
Hodkinson, C.6
Drake, M.B.7
Kettle, P.J.8
Morris, T.C.9
Alexander, H.D.10
-
42
-
-
77956962955
-
Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin
-
Buda G, Ricci D, Huang CC, Favis R, Cohen N, Zhuang SH, Harousseau JL, Sonneveld P, Blade J, Orlowski RZ. Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin. Ann Hematol 2010;89:1133-40.
-
(2010)
Ann Hematol
, vol.89
, pp. 1133-1140
-
-
Buda, G.1
Ricci, D.2
Huang, C.C.3
Favis, R.4
Cohen, N.5
Zhuang, S.H.6
Harousseau, J.L.7
Sonneveld, P.8
Blade, J.9
Orlowski, R.Z.10
-
43
-
-
33845530328
-
Association of folate transporter SLC19A1 polymorphisms with the outcome of multiple myeloma after chemotherapy and tandem autologous transplantation
-
Maggini V, Buda G, Galimberti S, et al. Association of folate transporter SLC19A1 polymorphisms with the outcome of multiple myeloma after chemotherapy and tandem autologous transplantation. Leukemia 2007;21:176-8.
-
(2007)
Leukemia
, vol.21
, pp. 176-178
-
-
Maggini, V.1
Buda, G.2
Galimberti, S.3
-
44
-
-
0035807079
-
Repair of DNA interstrand cross-links
-
Dronkert ML, Kanaar R. Repair of DNA interstrand cross-links. Mutat Res 2001;486:217-47.
-
(2001)
Mutat Res
, vol.486
, pp. 217-247
-
-
Dronkert, M.L.1
Kanaar, R.2
-
45
-
-
0036660428
-
Repair of DNA interstrand crosslinks as a mechanism of clinical resistance to melphalan in multiple myeloma
-
Spanswick VJ, Craddock C, Sekhar M, Mahendra P, Shankaranarayana P, Hughes RG, Hochhauser D, Hartley JA. Repair of DNA interstrand crosslinks as a mechanism of clinical resistance to melphalan in multiple myeloma. Blood 2002;100:224-9.
-
(2002)
Blood
, vol.100
, pp. 224-229
-
-
Spanswick, V.J.1
Craddock, C.2
Sekhar, M.3
Mahendra, P.4
Shankaranarayana, P.5
Hughes, R.G.6
Hochhauser, D.7
Hartley, J.A.8
-
46
-
-
0034054019
-
Nucleotide excision repair and human syndromes
-
de Boer J, Hoeijmakers JH. Nucleotide excision repair and human syndromes. Carcinogenesis 2000;21:453-60.
-
(2000)
Carcinogenesis
, vol.21
, pp. 453-460
-
-
de Boer, J.1
Hoeijmakers, J.H.2
-
47
-
-
0030768038
-
Nucleotide excision repair in mammalian cells
-
Wood RD. Nucleotide excision repair in mammalian cells. J Biol Chem 1997;272:23465-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 23465-23468
-
-
Wood, R.D.1
-
48
-
-
0036319509
-
Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts
-
Rockenbauer E, Bendixen MH, Bukowy Z, Yin J, Jacobsen NR, Hedayati M, Vogel U, Grossman L, Bolund L, Nexo BA. Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts. Carcinogenesis 2002;23:1149-53.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1149-1153
-
-
Rockenbauer, E.1
Bendixen, M.H.2
Bukowy, Z.3
Yin, J.4
Jacobsen, N.R.5
Hedayati, M.6
Vogel, U.7
Grossman, L.8
Bolund, L.9
Nexo, B.A.10
-
49
-
-
0037633990
-
A specific haplotype of single nucleotide polymorphisms on chromosome 19q13.2-3 encompassing the gene RAI is indicative of post-menopausal breast cancer before age 55
-
Nexo BA, Vogel U, Olsen A, Ketelsen T, Bukowy Z, Thomsen BL, Wallin H, Overvad K, Tjonneland A. A specific haplotype of single nucleotide polymorphisms on chromosome 19q13.2-3 encompassing the gene RAI is indicative of post-menopausal breast cancer before age 55. Carcinogenesis 2003;24:899-904.
-
(2003)
Carcinogenesis
, vol.24
, pp. 899-904
-
-
Nexo, B.A.1
Vogel, U.2
Olsen, A.3
Ketelsen, T.4
Bukowy, Z.5
Thomsen, B.L.6
Wallin, H.7
Overvad, K.8
Tjonneland, A.9
-
50
-
-
9144230618
-
Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer
-
Vogel U, Laros I, Jacobsen NR, et al. Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer. Mutat Res 2004;2:65-74.
-
(2004)
Mutat Res
, vol.2
, pp. 65-74
-
-
Vogel, U.1
Laros, I.2
Jacobsen, N.R.3
-
51
-
-
0034812088
-
XRCC1, XRCC3, XPD gene polymorphisms, smoking and (32)P-DNA adducts in a sample of healthy subjects
-
Matullo G, Palli D, Peluso M, et al. XRCC1, XRCC3, XPD gene polymorphisms, smoking and (32)P-DNA adducts in a sample of healthy subjects. Carcinogenesis 2001;22:1437-45.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1437-1445
-
-
Matullo, G.1
Palli, D.2
Peluso, M.3
-
52
-
-
0036122950
-
Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes
-
Qiao Y, Spitz MR, Shen H, Guo Z, Shete S, Hedayati M, Grossman L, Mohrenweiser H, Wei Q. Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes. Carcinogenesis 2002;23:295-9.
-
(2002)
Carcinogenesis
, vol.23
, pp. 295-299
-
-
Qiao, Y.1
Spitz, M.R.2
Shen, H.3
Guo, Z.4
Shete, S.5
Hedayati, M.6
Grossman, L.7
Mohrenweiser, H.8
Wei, Q.9
-
53
-
-
34250816848
-
Expression of the RAI gene is conducive to apoptosis: studies of induction and interference
-
Laska MJ, Strandbygard D, Kjeldgaard A, Mains M, Corydon TJ, Memon AA, Sorensen BS, Vogel U, Jensen UB, Nexo BA. Expression of the RAI gene is conducive to apoptosis: studies of induction and interference. Exp Cell Res 2007;313:2611-21.
-
(2007)
Exp Cell Res
, vol.313
, pp. 2611-2621
-
-
Laska, M.J.1
Strandbygard, D.2
Kjeldgaard, A.3
Mains, M.4
Corydon, T.J.5
Memon, A.A.6
Sorensen, B.S.7
Vogel, U.8
Jensen, U.B.9
Nexo, B.A.10
-
54
-
-
70249134606
-
Enforced expression of PPP1R13L increases tumorigenesis and invasion through p53-dependent and p53-independent mechanisms
-
Laska MJ, Lowe SW, Zender L, Hearn S, Vogel U, Jensen UB, Bric A, Nexo BA. Enforced expression of PPP1R13L increases tumorigenesis and invasion through p53-dependent and p53-independent mechanisms. Mol Carcinog 2009;48:832-42.
-
(2009)
Mol Carcinog
, vol.48
, pp. 832-842
-
-
Laska, M.J.1
Lowe, S.W.2
Zender, L.3
Hearn, S.4
Vogel, U.5
Jensen, U.B.6
Bric, A.7
Nexo, B.A.8
-
55
-
-
0031473229
-
ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes
-
Whitehead CM, Winkfein RJ, Fritzler MJ, Rattner JB. ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes. Chromosoma 1997;106:493-502.
-
(1997)
Chromosoma
, vol.106
, pp. 493-502
-
-
Whitehead, C.M.1
Winkfein, R.J.2
Fritzler, M.J.3
Rattner, J.B.4
-
56
-
-
0030054975
-
cDNA cloning and characterization of a novel nucleolar protein
-
Ochs RL, Stein TW Jr, Chan EK, Ruutu M, Tan EM. cDNA cloning and characterization of a novel nucleolar protein. Mol Biol Cell 1996;7:1015-24.
-
(1996)
Mol Biol Cell
, vol.7
, pp. 1015-1024
-
-
Ochs, R.L.1
Stein Jr., T.W.2
Chan, E.K.3
Ruutu, M.4
Tan, E.M.5
-
57
-
-
0033603051
-
CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells
-
Yamazaki T, Hamano Y, Tashiro H, Itoh K, Nakano H, Miyatake S, Saito T. CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells. J Biol Chem 1999;274:18173-80.
-
(1999)
J Biol Chem
, vol.274
, pp. 18173-18180
-
-
Yamazaki, T.1
Hamano, Y.2
Tashiro, H.3
Itoh, K.4
Nakano, H.5
Miyatake, S.6
Saito, T.7
-
58
-
-
61749101063
-
Association of a single nucleotide polymorphic variation in the human chromosome 19q13.3 with drug responses in the NCI60 cell lines
-
Nissen KK, Vogel U, Nexo BA. Association of a single nucleotide polymorphic variation in the human chromosome 19q13.3 with drug responses in the NCI60 cell lines. Anticancer Drugs 2009;20:174-8.
-
(2009)
Anticancer Drugs
, vol.20
, pp. 174-178
-
-
Nissen, K.K.1
Vogel, U.2
Nexo, B.A.3
-
59
-
-
0033048966
-
Identification of a novel inhibitor of nuclear factor-kappaB, RelA-associated inhibitor
-
Yang JP, Hori M, Sanda T, Okamoto T. Identification of a novel inhibitor of nuclear factor-kappaB, RelA-associated inhibitor. J Biol Chem 1999;274:15662-70.
-
(1999)
J Biol Chem
, vol.274
, pp. 15662-15670
-
-
Yang, J.P.1
Hori, M.2
Sanda, T.3
Okamoto, T.4
-
60
-
-
0037312920
-
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human
-
Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, et al. iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human. Nat Genet 2003;33:162-7.
-
(2003)
Nat Genet
, vol.33
, pp. 162-167
-
-
Bergamaschi, D.1
Samuels, Y.2
O'Neil, N.J.3
Trigiante, G.4
Crook, T.5
Hsieh, J.K.6
-
61
-
-
0032061317
-
XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
-
Liu N, Lamerdin JE, Tebbs RS, et al. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol Cell 1998;1:783-93.
-
(1998)
Mol Cell
, vol.1
, pp. 783-793
-
-
Liu, N.1
Lamerdin, J.E.2
Tebbs, R.S.3
-
62
-
-
0035802230
-
In vitro evidence for homologous recombinational repair in resistance to melphalan
-
Wang ZM, Chen ZP, Xu ZY, Christodoulopoulos G, Bello V, Mohr G, Aloyz R, Panasci LC. In vitro evidence for homologous recombinational repair in resistance to melphalan. J Natl Cancer Inst 2001;93:1473-8.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1473-1478
-
-
Wang, Z.M.1
Chen, Z.P.2
Xu, Z.Y.3
Christodoulopoulos, G.4
Bello, V.5
Mohr, G.6
Aloyz, R.7
Panasci, L.C.8
-
63
-
-
33846807527
-
Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation
-
Vangsted A, Gimsing P, Klausen TW, Nexo BA, Wallin H, Andersen P, Hokland P, Lillevang ST, Vogel U. Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation. Int J Cancer 2007;120:1036-45.
-
(2007)
Int J Cancer
, vol.120
, pp. 1036-1045
-
-
Vangsted, A.1
Gimsing, P.2
Klausen, T.W.3
Nexo, B.A.4
Wallin, H.5
Andersen, P.6
Hokland, P.7
Lillevang, S.T.8
Vogel, U.9
-
64
-
-
79956150198
-
The importance of a sub-region on chromosome 19q13.3 for prognosis of multiple myeloma patients after high-dose treatment and stem cell support: a linkage disequilibrium mapping in RAI and CD3EAP
-
Vangsted AJ, Klausen TW, Gimsing P, Abildgaard N, Andersen NF, Gregersen H, Nexo BA, Vogel UB. The importance of a sub-region on chromosome 19q13.3 for prognosis of multiple myeloma patients after high-dose treatment and stem cell support: a linkage disequilibrium mapping in RAI and CD3EAP. Ann Hematol 2011;90:675-84.
-
(2011)
Ann Hematol
, vol.90
, pp. 675-684
-
-
Vangsted, A.J.1
Klausen, T.W.2
Gimsing, P.3
Abildgaard, N.4
Andersen, N.F.5
Gregersen, H.6
Nexo, B.A.7
Vogel, U.B.8
-
65
-
-
34547677725
-
Immunodeficiency and immunotherapy in multiple myeloma
-
Pratt G, Goodyear O, Moss P. Immunodeficiency and immunotherapy in multiple myeloma. Br J Haematol 2007;138:563-79.
-
(2007)
Br J Haematol
, vol.138
, pp. 563-579
-
-
Pratt, G.1
Goodyear, O.2
Moss, P.3
-
66
-
-
0033868516
-
High-producer haplotypes of tumor necrosis factor alpha and lymphotoxin alpha are associated with an increased risk of myeloma and have an improved progression-free survival after treatment
-
Davies FE, Rollinson SJ, Rawstron AC, Roman E, Richards S, Drayson M, Child JA, Morgan GJ. High-producer haplotypes of tumor necrosis factor alpha and lymphotoxin alpha are associated with an increased risk of myeloma and have an improved progression-free survival after treatment. J Clin Oncol 2000;18:2843-51.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2843-2851
-
-
Davies, F.E.1
Rollinson, S.J.2
Rawstron, A.C.3
Roman, E.4
Richards, S.5
Drayson, M.6
Child, J.A.7
Morgan, G.J.8
-
67
-
-
64949158459
-
The polymorphism IL-1beta T-31C is associated with a longer overall survival in patients with multiple myeloma undergoing auto-SCT
-
Vangsted AJ, Klausen TW, Ruminski W, et al. The polymorphism IL-1beta T-31C is associated with a longer overall survival in patients with multiple myeloma undergoing auto-SCT. Bone Marrow Transplant 2009;43:539-45.
-
(2009)
Bone Marrow Transplant
, vol.43
, pp. 539-545
-
-
Vangsted, A.J.1
Klausen, T.W.2
Ruminski, W.3
-
68
-
-
75549091673
-
The IL-1 family: regulators of immunity
-
Sims JE, Smith DE. The IL-1 family: regulators of immunity. Nat Rev Immunol 2010;10:89-102.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 89-102
-
-
Sims, J.E.1
Smith, D.E.2
-
69
-
-
0032428364
-
Interleukin-1 in multiple myeloma: producer cells and their role in the control of IL-6 production
-
Costes V, Portier M, Lu ZY, Rossi JF, Bataille R, Klein B. Interleukin-1 in multiple myeloma: producer cells and their role in the control of IL-6 production. Br J Haematol 1998;103:1152-60.
-
(1998)
Br J Haematol
, vol.103
, pp. 1152-1160
-
-
Costes, V.1
Portier, M.2
Lu, Z.Y.3
Rossi, J.F.4
Bataille, R.5
Klein, B.6
-
70
-
-
0032954020
-
Comparison of interleukin-1 beta expression by in situ hybridization in monoclonal gammopathy of undetermined significance and multiple myeloma
-
Lacy MQ, Donovan KA, Heimbach JK, Ahmann GJ, Lust JA. Comparison of interleukin-1 beta expression by in situ hybridization in monoclonal gammopathy of undetermined significance and multiple myeloma. Blood 1999;93:300-5.
-
(1999)
Blood
, vol.93
, pp. 300-305
-
-
Lacy, M.Q.1
Donovan, K.A.2
Heimbach, J.K.3
Ahmann, G.J.4
Lust, J.A.5
-
71
-
-
32144455365
-
Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context
-
Chen H, Wilkins LM, Aziz N, et al. Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context. Hum Mol Genet 2006;15:519-29.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 519-529
-
-
Chen, H.1
Wilkins, L.M.2
Aziz, N.3
-
72
-
-
80055101222
-
Single nucleotide polymorphisms in the promoter region of the IL1B gene influence outcome in multiple myeloma patients treated with high-dose chemotherapy independently of relapse treatment with thalidomide and bortezomib
-
Vangsted AJ, Klausen TW, Abildgaard N, Anderson NF, Gimsing P, Gregersen H, Nexø BA, Vogel U. Single nucleotide polymorphisms in the promoter region of the IL1B gene influence outcome in multiple myeloma patients treated with high-dose chemotherapy independently of relapse treatment with thalidomide and bortezomib. Annals of Haematology 2011;doi:.
-
(2011)
Annals of Haematology
-
-
Vangsted, A.J.1
Klausen, T.W.2
Abildgaard, N.3
Anderson, N.F.4
Gimsing, P.5
Gregersen, H.6
Nexø, B.A.7
Vogel, U.8
-
73
-
-
0031657551
-
How cells respond to interferons
-
Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD. How cells respond to interferons. Annu Rev Biochem 1998;67:227-64.
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
74
-
-
79551617380
-
Interferon-alpha in the Treatment of Multiple Myeloma
-
Khoo TL, Vangsted AJ, Gibson J. Interferon-alpha in the Treatment of Multiple Myeloma. Curr Drug Targets 2011;15:437-46.
-
(2011)
Curr Drug Targets
, vol.15
, pp. 437-446
-
-
Khoo, T.L.1
Vangsted, A.J.2
Gibson, J.3
-
75
-
-
0035496921
-
Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma
-
Chen Q, Gong B, Mahmoud-Ahmed AS, Zhou A, Hsi ED, Hussein M, Almasan A. Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma. Blood 2001;98:2183-92.
-
(2001)
Blood
, vol.98
, pp. 2183-2192
-
-
Chen, Q.1
Gong, B.2
Mahmoud-Ahmed, A.S.3
Zhou, A.4
Hsi, E.D.5
Hussein, M.6
Almasan, A.7
-
76
-
-
0030881360
-
Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression
-
Jelinek DF, Aagaard-Tillery KM, Arendt BK, Arora T, Tschumper RC, Westendorf JJ. Differential human multiple myeloma cell line responsiveness to interferon-alpha. Analysis of transcription factor activation and interleukin 6 receptor expression. J Clin Invest 1997;99:447-56.
-
(1997)
J Clin Invest
, vol.99
, pp. 447-456
-
-
Jelinek, D.F.1
Aagaard-Tillery, K.M.2
Arendt, B.K.3
Arora, T.4
Tschumper, R.C.5
Westendorf, J.J.6
-
77
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell JE Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994;264:1415-21.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.R.3
-
78
-
-
36849082588
-
Non-conventional signal transduction by type 1 interferons: the NF-kappaB pathway
-
Du Z, Wei L, Murti A, Pfeffer SR, Fan M, Yang CH, Pfeffer LM. Non-conventional signal transduction by type 1 interferons: the NF-kappaB pathway. J Cell Biochem 2007;102:1087-94.
-
(2007)
J Cell Biochem
, vol.102
, pp. 1087-1094
-
-
Du, Z.1
Wei, L.2
Murti, A.3
Pfeffer, S.R.4
Fan, M.5
Yang, C.H.6
Pfeffer, L.M.7
-
79
-
-
33644920953
-
Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321
-
Barlogie B, Kyle RA, Anderson KC, et al. Standard chemotherapy compared with high-dose chemoradiotherapy for multiple myeloma: final results of phase III US Intergroup Trial S9321. J Clin Oncol 2006;24:929-36.
-
(2006)
J Clin Oncol
, vol.24
, pp. 929-936
-
-
Barlogie, B.1
Kyle, R.A.2
Anderson, K.C.3
-
80
-
-
7344264989
-
A randomized trial of maintenance interferon following high-dose chemotherapy in multiple myeloma: long-term follow-up results
-
Cunningham D, Powles R, Malpas J, et al. A randomized trial of maintenance interferon following high-dose chemotherapy in multiple myeloma: long-term follow-up results. Br J Haematol 1998;102:495-502.
-
(1998)
Br J Haematol
, vol.102
, pp. 495-502
-
-
Cunningham, D.1
Powles, R.2
Malpas, J.3
-
81
-
-
0034933036
-
Interferon as therapy for multiple myeloma: an individual patient data overview of 24 randomized trials and 4012 patients
-
Interferon as therapy for multiple myeloma: an individual patient data overview of 24 randomized trials and 4012 patients. Br J Haematol 2001;113:1020-34.
-
(2001)
Br J Haematol
, vol.113
, pp. 1020-1034
-
-
-
82
-
-
70349092296
-
A polymorphism in NFKB1 is associated with improved effect of interferon-{alpha} maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support
-
Vangsted AJ, Klausen TW, Gimsing P, Andersen NF, Abildgaard N, Gregersen H, Vogel U. A polymorphism in NFKB1 is associated with improved effect of interferon-{alpha} maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support. Haematologica 2009;94:1274-81.
-
(2009)
Haematologica
, vol.94
, pp. 1274-1281
-
-
Vangsted, A.J.1
Klausen, T.W.2
Gimsing, P.3
Andersen, N.F.4
Abildgaard, N.5
Gregersen, H.6
Vogel, U.7
-
83
-
-
0035933772
-
Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity
-
Keifer JA, Guttridge DC, Ashburner BP, Baldwin AS Jr. Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity. J Biol Chem 2001;276:22382-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 22382-22387
-
-
Keifer, J.A.1
Guttridge, D.C.2
Ashburner, B.P.3
Baldwin Jr., A.S.4
-
84
-
-
0037097595
-
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications
-
Mitsiades N, Mitsiades CS, Poulaki V, Chauhan D, Richardson PG, Hideshima T, Munshi NC, Treon SP, Anderson KC. Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications. Blood 2002;99:4525-30.
-
(2002)
Blood
, vol.99
, pp. 4525-4530
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Richardson, P.G.5
Hideshima, T.6
Munshi, N.C.7
Treon, S.P.8
Anderson, K.C.9
-
86
-
-
0033168605
-
Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
-
Corral LG, Haslett PA, Muller GW, Chen R, Wong LM, Ocampo CJ, Patterson RT, Stirling DI, Kaplan G. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol 1999;163:380-6.
-
(1999)
J Immunol
, vol.163
, pp. 380-386
-
-
Corral, L.G.1
Haslett, P.A.2
Muller, G.W.3
Chen, R.4
Wong, L.M.5
Ocampo, C.J.6
Patterson, R.T.7
Stirling, D.I.8
Kaplan, G.9
-
87
-
-
0029925419
-
Thalidomide selectively modulates the density of cell surface molecules involved in the adhesion cascade
-
Geitz H, Handt S, Zwingenberger K. Thalidomide selectively modulates the density of cell surface molecules involved in the adhesion cascade. Immunopharmacology 1996;3:213-21.
-
(1996)
Immunopharmacology
, vol.3
, pp. 213-221
-
-
Geitz, H.1
Handt, S.2
Zwingenberger, K.3
-
88
-
-
0037105593
-
Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma
-
Neben K, Mytilineos J, Moehler TM, Preiss A, Kraemer A, Ho AD, Opelz G, Goldschmidt H. Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma. Blood 2002;100:2263-5.
-
(2002)
Blood
, vol.100
, pp. 2263-2265
-
-
Neben, K.1
Mytilineos, J.2
Moehler, T.M.3
Preiss, A.4
Kraemer, A.5
Ho, A.D.6
Opelz, G.7
Goldschmidt, H.8
-
89
-
-
77957021714
-
Role of the TNF-alpha promoter polymorphisms for development of multiple myeloma and clinical outcome in thalidomide plus dexamethasone
-
Du J, Yuan Z, Zhang C, Fu W, Jiang H, Chen B, Hou J. Role of the TNF-alpha promoter polymorphisms for development of multiple myeloma and clinical outcome in thalidomide plus dexamethasone. Leuk Res 2010;34:1453-8.
-
(2010)
Leuk Res
, vol.34
, pp. 1453-1458
-
-
Du, J.1
Yuan, Z.2
Zhang, C.3
Fu, W.4
Jiang, H.5
Chen, B.6
Hou, J.7
-
90
-
-
79955738089
-
Polymorphisms of nuclear factor-{kappa}B family genes are associated with development of multiple myeloma and treatment outcome in patients receiving bortezomib-based regimens
-
Du J, Huo J, Shi J, Yuan Z, Zhang C, Fu W, Jiang H, Yi Q, Hou J. Polymorphisms of nuclear factor-{kappa}B family genes are associated with development of multiple myeloma and treatment outcome in patients receiving bortezomib-based regimens. Haematologica 2011;96:729-37.
-
(2011)
Haematologica
, vol.96
, pp. 729-737
-
-
Du, J.1
Huo, J.2
Shi, J.3
Yuan, Z.4
Zhang, C.5
Fu, W.6
Jiang, H.7
Yi, Q.8
Hou, J.9
-
91
-
-
33749439349
-
MBL2 polymorphism and risk of severe infections in multiple myeloma patients receiving high-dose melphalan and autologous stem cell transplantation
-
Molle I, Peterslund NA, Thiel S, Steffensen R. MBL2 polymorphism and risk of severe infections in multiple myeloma patients receiving high-dose melphalan and autologous stem cell transplantation. Bone Marrow Transplant 2006;38:555-60.
-
(2006)
Bone Marrow Transplant
, vol.38
, pp. 555-560
-
-
Molle, I.1
Peterslund, N.A.2
Thiel, S.3
Steffensen, R.4
-
92
-
-
46749140594
-
Infectious complications after chemotherapy and stem cell transplantation in multiple myeloma: implications of Fc gamma receptor and myeloperoxidase promoter polymorphisms
-
Molle I, Ostergaard M, Melsvik D, Nyvold CG. Infectious complications after chemotherapy and stem cell transplantation in multiple myeloma: implications of Fc gamma receptor and myeloperoxidase promoter polymorphisms. Leuk Lymphoma 2008;49:1116-22.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 1116-1122
-
-
Molle, I.1
Ostergaard, M.2
Melsvik, D.3
Nyvold, C.G.4
-
93
-
-
60549116502
-
[Bisphosphonate-associated osteonecrosis of the jaw in patients with multiple myeloma]
-
Lund T, Gregersen H, Vangsted A, Marker P, Abildgaard N. [Bisphosphonate-associated osteonecrosis of the jaw in patients with multiple myeloma]. Ugeskr Laeger 2009;2:50-2.
-
(2009)
Ugeskr Laeger
, vol.2
, pp. 50-52
-
-
Lund, T.1
Gregersen, H.2
Vangsted, A.3
Marker, P.4
Abildgaard, N.5
-
94
-
-
0042861578
-
Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic
-
Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg 2003;61:1115-7.
-
(2003)
J Oral Maxillofac Surg
, vol.61
, pp. 1115-1117
-
-
Marx, R.E.1
-
96
-
-
79960838263
-
A peroxisome proliferator-activated receptor gamma (PPARG) polymorphism is associated with zoledronic acid-related osteonecrosis of the jaw in multiple myeloma patients: analysis by DMET microarray profiling
-
Di Martino MT, Arbitrio M, Guzzi PH, et al. A peroxisome proliferator-activated receptor gamma (PPARG) polymorphism is associated with zoledronic acid-related osteonecrosis of the jaw in multiple myeloma patients: analysis by DMET microarray profiling. Br J Haematol 2011;154:529-33.
-
(2011)
Br J Haematol
, vol.154
, pp. 529-533
-
-
Di Martino, M.T.1
Arbitrio, M.2
Guzzi, P.H.3
-
97
-
-
0035851187
-
PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen ED, Spiegelman BM. PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 2001;276:37731-4.
-
(2001)
J Biol Chem
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
98
-
-
58149380751
-
Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping
-
Johnson DC, Corthals S, Ramos C, et al. Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping. Blood 2008;112:4924-34.
-
(2008)
Blood
, vol.112
, pp. 4924-4934
-
-
Johnson, D.C.1
Corthals, S.2
Ramos, C.3
-
99
-
-
63849240546
-
Dysfunctional homologous recombination mediates genomic instability and progression in myeloma
-
Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC. Dysfunctional homologous recombination mediates genomic instability and progression in myeloma. Blood 2009;113:2290-7.
-
(2009)
Blood
, vol.113
, pp. 2290-2297
-
-
Shammas, M.A.1
Shmookler Reis, R.J.2
Koley, H.3
Batchu, R.B.4
Li, C.5
Munshi, N.C.6
-
100
-
-
33644844811
-
Identification of two groups of smoldering multiple myeloma patients who are either high or low producers of interleukin-1
-
Xiong Y, Donovan KA, Kline MP, Gornet MK, Moon-Tasson LL, Lacy MQ, Dispenzieri A, Gertz MA, Greipp PR, Lust JA. Identification of two groups of smoldering multiple myeloma patients who are either high or low producers of interleukin-1. J Interferon Cytokine Res 2006;26:83-95.
-
(2006)
J Interferon Cytokine Res
, vol.26
, pp. 83-95
-
-
Xiong, Y.1
Donovan, K.A.2
Kline, M.P.3
Gornet, M.K.4
Moon-Tasson, L.L.5
Lacy, M.Q.6
Dispenzieri, A.7
Gertz, M.A.8
Greipp, P.R.9
Lust, J.A.10
-
101
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
Ghiringhelli F, Apetoh L, Tesniere A, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 2009;15:1170-8.
-
(2009)
Nat Med
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
-
103
-
-
79955461011
-
Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study
-
Moreau P, Pylypenko H, Grosicki S, et al. Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study. Lancet Oncol 2011;12:431-40.
-
(2011)
Lancet Oncol
, vol.12
, pp. 431-440
-
-
Moreau, P.1
Pylypenko, H.2
Grosicki, S.3
-
104
-
-
20644460600
-
International staging system for multiple myeloma
-
Greipp PR, San Miguel J, Durie BG, et al. International staging system for multiple myeloma. J Clin Oncol 2005;23:3412-20.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3412-3420
-
-
Greipp, P.R.1
San Miguel, J.2
Durie, B.G.3
-
105
-
-
77449136592
-
Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment
-
Rodriguez-Antona C, Gomez A, Karlgren M, Sim SC, Ingelman-Sundberg M. Molecular genetics and epigenetics of the cytochrome P450 gene family and its relevance for cancer risk and treatment. Hum Genet 2010;127:1-17.
-
(2010)
Hum Genet
, vol.127
, pp. 1-17
-
-
Rodriguez-Antona, C.1
Gomez, A.2
Karlgren, M.3
Sim, S.C.4
Ingelman-Sundberg, M.5
-
106
-
-
54949144309
-
Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
-
Zanger UM, Turpeinen M, Klein K, Schwab M. Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation. Anal Bioanal Chem 2008;392:1093-108.
-
(2008)
Anal Bioanal Chem
, vol.392
, pp. 1093-1108
-
-
Zanger, U.M.1
Turpeinen, M.2
Klein, K.3
Schwab, M.4
-
107
-
-
0037739753
-
High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
-
Child JA, Morgan GJ, Davies FE, Owen RG, Bell SE, Hawkins K, Brown J, Drayson MT, Selby PJ. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003;348:1875-83.
-
(2003)
N Engl J Med
, vol.348
, pp. 1875-1883
-
-
Child, J.A.1
Morgan, G.J.2
Davies, F.E.3
Owen, R.G.4
Bell, S.E.5
Hawkins, K.6
Brown, J.7
Drayson, M.T.8
Selby, P.J.9
-
108
-
-
34548539381
-
Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression
-
Orlowski RZ, Nagler A, Sonneveld P, et al. Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression. J Clin Oncol 2007;25:3892-901.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3892-3901
-
-
Orlowski, R.Z.1
Nagler, A.2
Sonneveld, P.3
-
109
-
-
30644463628
-
The P2X7 receptor gene polymorphism 1513 A-->C has no effect on clinical prognostic markers and survival in multiple myeloma
-
Paneesha S, Starczynski J, Pepper C, Delgado J, Hooper L, Fegan C, Pratt G. The P2X7 receptor gene polymorphism 1513 A-->C has no effect on clinical prognostic markers and survival in multiple myeloma. Leuk Lymphoma 2006;47:281-4.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 281-284
-
-
Paneesha, S.1
Starczynski, J.2
Pepper, C.3
Delgado, J.4
Hooper, L.5
Fegan, C.6
Pratt, G.7
-
110
-
-
69549116517
-
MDR1 C3435T polymorphism indicates a different outcome in advanced multiple myeloma
-
Buda G, Martino A, Maggini V, et al. MDR1 C3435T polymorphism indicates a different outcome in advanced multiple myeloma. Acta Haematol 2009;122:42-5.
-
(2009)
Acta Haematol
, vol.122
, pp. 42-45
-
-
Buda, G.1
Martino, A.2
Maggini, V.3
-
111
-
-
77954699156
-
The G-Allele of the PSMA6-8C>G polymorphism is associated with poor outcome in multiple myeloma independently of circulating proteasome serum levels
-
Bachmann HS, Novotny J, Sixt S, Liebisch P, Frey UH, Duhrsen U, Siffert W, Nuckel H. The G-Allele of the PSMA6-8C>G polymorphism is associated with poor outcome in multiple myeloma independently of circulating proteasome serum levels. Eur J Haematol 2010;85:108-13.
-
(2010)
Eur J Haematol
, vol.85
, pp. 108-113
-
-
Bachmann, H.S.1
Novotny, J.2
Sixt, S.3
Liebisch, P.4
Frey, U.H.5
Duhrsen, U.6
Siffert, W.7
Nuckel, H.8
-
112
-
-
53449093633
-
Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis
-
Sarasquete ME, Gonzalez M, San Miguel JF, Garcia-Sanz R. Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis. Blood 2008;112:2709-12.
-
(2008)
Blood
, vol.112
, pp. 2709-2712
-
-
Sarasquete, M.E.1
Gonzalez, M.2
San Miguel, J.F.3
Garcia-Sanz, R.4
-
113
-
-
78049528598
-
Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial
-
Broyl A, Corthals SL, Jongen JL, et al. Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial. Lancet Oncol 2010;11:1057-65.
-
(2010)
Lancet Oncol
, vol.11
, pp. 1057-1065
-
-
Broyl, A.1
Corthals, S.L.2
Jongen, J.L.3
-
114
-
-
79951672140
-
Genetic variation associated with bortezomib-induced peripheral neuropathy
-
Favis R, Sun Y, van de Velde H, Broderick E, Levey L, Meyers M, Mulligan G, Harousseau JL, Richardson PG, Ricci DS. Genetic variation associated with bortezomib-induced peripheral neuropathy. Pharmacogenet Genomics 2011;21:121-9.
-
(2011)
Pharmacogenet Genomics
, vol.21
, pp. 121-129
-
-
Favis, R.1
Sun, Y.2
van de Velde, H.3
Broderick, E.4
Levey, L.5
Meyers, M.6
Mulligan, G.7
Harousseau, J.L.8
Richardson, P.G.9
Ricci, D.S.10
-
115
-
-
79952322815
-
Genetic factors underlying the risk of thalidomide-related neuropathy in patients with multiple myeloma
-
Johnson DC, Corthals SL, Walker BA, et al. Genetic factors underlying the risk of thalidomide-related neuropathy in patients with multiple myeloma. J Clin Oncol 2011;29:797-804.
-
(2011)
J Clin Oncol
, vol.29
, pp. 797-804
-
-
Johnson, D.C.1
Corthals, S.L.2
Walker, B.A.3
|