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Volumn 15, Issue 6, 2009, Pages 382-387

Bisphosphonate-related osteonecrosis: Genetic and acquired risk factors

Author keywords

Bisphosphonates; Genetic risk factors; Osteonecrosis of the jaw

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CYTOCHROME P450 2C8; ETIDRONIC ACID; PAMIDRONIC ACID; ZOLEDRONIC ACID;

EID: 68949219104     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2009.01568.x     Document Type: Review
Times cited : (55)

References (64)
  • 1
    • 33847284113 scopus 로고    scopus 로고
    • American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws
    • Advisory Task Force on Bisphosphonate-Related Ostenonecrosis of the Jaws AAoOaMS
    • Advisory Task Force on Bisphosphonate-Related Ostenonecrosis of the Jaws AAoOaMS (2007). American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg 65: 369 376.
    • (2007) J Oral Maxillofac Surg , vol.65 , pp. 369-376
  • 2
    • 0942276839 scopus 로고    scopus 로고
    • The intronic prothrombin 19911A>G polymorphism influences splicing efficiency and modulates effects of the 20210G>A polymorphism on mRNA amount and expression in a stable reporter gene assay system
    • von Ahsen N, Oellerich M (2004). The intronic prothrombin 19911A>G polymorphism influences splicing efficiency and modulates effects of the 20210G>A polymorphism on mRNA amount and expression in a stable reporter gene assay system. Blood 103: 586 593.
    • (2004) Blood , vol.103 , pp. 586-593
    • Von Ahsen, N.1    Oellerich, M.2
  • 3
    • 33644906138 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in multiple myeloma patients: Clinical features and risk factors
    • Badros A, Weikel D, Salama A et al (2006). Osteonecrosis of the jaw in multiple myeloma patients: clinical features and risk factors. J Clin Oncol 24: 945 952.
    • (2006) J Clin Oncol , vol.24 , pp. 945-952
    • Badros, A.1    Weikel, D.2    Salama, A.3
  • 4
    • 58049204529 scopus 로고    scopus 로고
    • Natural history of osteonecrosis of the jaw in patients with multiple myeloma
    • Badros A, Terpos E, Katodritou E et al (2008). Natural history of osteonecrosis of the jaw in patients with multiple myeloma. J Clin Oncol 26: 5904 5909.
    • (2008) J Clin Oncol , vol.26 , pp. 5904-5909
    • Badros, A.1    Terpos, E.2    Katodritou, E.3
  • 5
    • 32644455093 scopus 로고    scopus 로고
    • Jaw osteonecrosis associated with bisphosphonates: Multiple exposed areas and its relationship to teeth extractions. Study of 20 cases
    • Bagan JV, Jimenez Y, Murillo J et al (2006). Jaw osteonecrosis associated with bisphosphonates: multiple exposed areas and its relationship to teeth extractions. Study of 20 cases. Oral Oncol 42: 327 329.
    • (2006) Oral Oncol , vol.42 , pp. 327-329
    • Bagan, J.V.1    Jimenez, Y.2    Murillo, J.3
  • 6
    • 67449096723 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): A concise update
    • Epub ahead of print
    • Bagan J, Scully C, Sabater V, Jimenez Y (2009). Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): a concise update. Oral Oncol [Epub ahead of print].
    • (2009) Oral Oncol
    • Bagan, J.1    Scully, C.2    Sabater, V.3    Jimenez, Y.4
  • 7
    • 33644841755 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors
    • Bamias A, Kastritis E, Bamia C et al (2005). Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: incidence and risk factors. J Clin Oncol 23: 8580 8587.
    • (2005) J Clin Oncol , vol.23 , pp. 8580-8587
    • Bamias, A.1    Kastritis, E.2    Bamia, C.3
  • 8
    • 0025916366 scopus 로고
    • Effect of daily etidronate on the osteolysis of multiple myeloma
    • Belch AR, Bergsagel DE, Wilson K et al (1991). Effect of daily etidronate on the osteolysis of multiple myeloma. J Clin Oncol 9: 1397 1402.
    • (1991) J Clin Oncol , vol.9 , pp. 1397-1402
    • Belch, A.R.1    Bergsagel, D.E.2    Wilson, K.3
  • 9
    • 9044219839 scopus 로고    scopus 로고
    • Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group
    • Berenson JR, Lichtenstein A, Porter L et al (1996). Efficacy of pamidronate in reducing skeletal events in patients with advanced multiple myeloma. Myeloma Aredia Study Group. N Engl J Med 334: 488 493.
    • (1996) N Engl J Med , vol.334 , pp. 488-493
    • Berenson, J.R.1    Lichtenstein, A.2    Porter, L.3
  • 10
    • 6844252283 scopus 로고    scopus 로고
    • Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group
    • Berenson JR, Lichtenstein A, Porter L et al (1998). Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group. J Clin Oncol 16: 593 602.
    • (1998) J Clin Oncol , vol.16 , pp. 593-602
    • Berenson, J.R.1    Lichtenstein, A.2    Porter, L.3
  • 11
    • 0036729485 scopus 로고    scopus 로고
    • American Society of Clinical Oncology Clinical Practice Guidelines: The role of bisphosphonates in multiple myeloma
    • Berenson JR, Hillner BE, Kyle RA et al (2002). American Society of Clinical Oncology Clinical Practice Guidelines: the role of bisphosphonates in multiple myeloma. J Clin Oncol 20: 3719 3736.
    • (2002) J Clin Oncol , vol.20 , pp. 3719-3736
    • Berenson, J.R.1    Hillner, B.E.2    Kyle, R.A.3
  • 12
    • 33751111432 scopus 로고    scopus 로고
    • Treatment strategies for skeletal complications of cancer
    • Berenson JR, Rajdev L, Broder M (2006). Treatment strategies for skeletal complications of cancer. Cancer Biol Ther 5: 1074 1077.
    • (2006) Cancer Biol Ther , vol.5 , pp. 1074-1077
    • Berenson, J.R.1    Rajdev, L.2    Broder, M.3
  • 13
    • 36549014240 scopus 로고    scopus 로고
    • Bisphosphonates and osteomyelitis of the jaw: A pathogenic puzzle
    • Bertoldo F, Santini D, Lo CV (2007). Bisphosphonates and osteomyelitis of the jaw: a pathogenic puzzle. Nat Clin Pract Oncol 4: 711 721.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 711-721
    • Bertoldo, F.1    Santini, D.2    Lo, C.V.3
  • 14
    • 33751528987 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw - Do bisphosphonates pose a risk?
    • Bilezikian JP (2006). Osteonecrosis of the jaw - do bisphosphonates pose a risk? N Engl J Med 355: 2278 2281.
    • (2006) N Engl J Med , vol.355 , pp. 2278-2281
    • Bilezikian, J.P.1
  • 15
    • 0033993749 scopus 로고    scopus 로고
    • Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase
    • Capdevila JH, Falck JR, Harris RC (2000). Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase. J Lipid Res 41: 163 181.
    • (2000) J Lipid Res , vol.41 , pp. 163-181
    • Capdevila, J.H.1    Falck, J.R.2    Harris, R.C.3
  • 16
    • 0027411455 scopus 로고
    • Multiple myeloma: Effect of daily dichloromethylene bisphosphonate on skeletal complications
    • Clemens MR, Fessele K, Heim ME (1993). Multiple myeloma: effect of daily dichloromethylene bisphosphonate on skeletal complications. Ann Hematol 66: 141 146.
    • (1993) Ann Hematol , vol.66 , pp. 141-146
    • Clemens, M.R.1    Fessele, K.2    Heim, M.E.3
  • 17
    • 0041709185 scopus 로고    scopus 로고
    • The role of prenylated small GTP-binding proteins in the regulation of osteoclast function
    • Coxon FP, Rogers MJ (2003). The role of prenylated small GTP-binding proteins in the regulation of osteoclast function. Calcif Tissue Int 72: 80 84.
    • (2003) Calcif Tissue Int , vol.72 , pp. 80-84
    • Coxon, F.P.1    Rogers, M.J.2
  • 18
    • 33744475085 scopus 로고    scopus 로고
    • A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter
    • De Gobbi M, Viprakasit V, Hughes JR et al (2006). A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. Science 312: 1215 1217.
    • (2006) Science , vol.312 , pp. 1215-1217
    • De Gobbi, M.1    Viprakasit, V.2    Hughes, J.R.3
  • 19
    • 0020436881 scopus 로고
    • Long-term effects of dichloromethylene diphosphonate (CI2MDP) on skeletal lesions in multiple myeloma
    • Delmas PD, Charhon S, Chapuy MC et al (1982). Long-term effects of dichloromethylene diphosphonate (CI2MDP) on skeletal lesions in multiple myeloma. Metab Bone Dis Relat Res 4: 163 168.
    • (1982) Metab Bone Dis Relat Res , vol.4 , pp. 163-168
    • Delmas, P.D.1    Charhon, S.2    Chapuy, M.C.3
  • 20
    • 33745792743 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates: Evidence of increased risk after treatment with zoledronic acid
    • Dimopoulos MA, Kastritis E, Anagnostopoulos A et al (2006). Osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates: evidence of increased risk after treatment with zoledronic acid. Haematologica 91: 968 971.
    • (2006) Haematologica , vol.91 , pp. 968-971
    • Dimopoulos, M.A.1    Kastritis, E.2    Anagnostopoulos, A.3
  • 21
    • 58949104001 scopus 로고    scopus 로고
    • Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid
    • Dimopoulos MA, Kastritis E, Bamia C et al (2009). Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid. Ann Oncol 20: 117 120.
    • (2009) Ann Oncol , vol.20 , pp. 117-120
    • Dimopoulos, M.A.1    Kastritis, E.2    Bamia, C.3
  • 22
    • 21444449880 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw and bisphosphonates
    • Durie BG, Katz M, Crowley J (2005). Osteonecrosis of the jaw and bisphosphonates. N Engl J Med 353: 99 102.
    • (2005) N Engl J Med , vol.353 , pp. 99-102
    • Durie, B.G.1    Katz, M.2    Crowley, J.3
  • 23
    • 56449103037 scopus 로고    scopus 로고
    • Pharmacovigilance and reporting oversight in US FDA fast-track process: Bisphosphonates and osteonecrosis of the jaw
    • Edwards BJ, Gounder M, McKoy JM et al (2008). Pharmacovigilance and reporting oversight in US FDA fast-track process: bisphosphonates and osteonecrosis of the jaw. Lancet Oncol 9: 1166 1172.
    • (2008) Lancet Oncol , vol.9 , pp. 1166-1172
    • Edwards, B.J.1    Gounder, M.2    McKoy, J.M.3
  • 25
    • 33845346159 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids, cell signaling and angiogenesis
    • Fleming I (2007). Epoxyeicosatrienoic acids, cell signaling and angiogenesis. Prostaglandins Other Lipid Mediat 82: 60 67.
    • (2007) Prostaglandins Other Lipid Mediat , vol.82 , pp. 60-67
    • Fleming, I.1
  • 26
    • 20944438107 scopus 로고    scopus 로고
    • Functional characterization of five novel CYP2C8 variants, G171S, R186X, R186G, K247R, and K383N, found in a Japanese population
    • Hichiya H, Tanaka-Kagawa T, Soyama A et al (2005). Functional characterization of five novel CYP2C8 variants, G171S, R186X, R186G, K247R, and K383N, found in a Japanese population. Drug Metab Dispos 33: 630 636.
    • (2005) Drug Metab Dispos , vol.33 , pp. 630-636
    • Hichiya, H.1    Tanaka-Kagawa, T.2    Soyama, A.3
  • 27
    • 34447560176 scopus 로고    scopus 로고
    • Genetic polymorphism of cytochrome P450s and P-glycoprotein in the Finnish population
    • Hilli J, Rane A, Lundgren S, Bertilsson L, Laine K (2007). Genetic polymorphism of cytochrome P450s and P-glycoprotein in the Finnish population. Fundam Clin Pharmacol 21: 379 386.
    • (2007) Fundam Clin Pharmacol , vol.21 , pp. 379-386
    • Hilli, J.1    Rane, A.2    Lundgren, S.3    Bertilsson, L.4    Laine, K.5
  • 28
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn JN, Daly MJ (2005). Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 6: 95 108.
    • (2005) Nat Rev Genet , vol.6 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 29
    • 44449153039 scopus 로고    scopus 로고
    • Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates
    • Hoff AO, Toth BB, Altundag K et al (2008). Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates. J Bone Miner Res 23: 826 836.
    • (2008) J Bone Miner Res , vol.23 , pp. 826-836
    • Hoff, A.O.1    Toth, B.B.2    Altundag, K.3
  • 30
    • 36148976077 scopus 로고    scopus 로고
    • Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects
    • Ingelman-Sundberg M, Sim SC, Gomez A, Rodriguez-Antona C (2007). Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacol Ther 116: 496 526.
    • (2007) Pharmacol Ther , vol.116 , pp. 496-526
    • Ingelman-Sundberg, M.1    Sim, S.C.2    Gomez, A.3    Rodriguez-Antona, C.4
  • 31
    • 34848841461 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
    • Khosla S, Burr D, Cauley J et al (2007). Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 22: 1479 1491.
    • (2007) J Bone Miner Res , vol.22 , pp. 1479-1491
    • Khosla, S.1    Burr, D.2    Cauley, J.3
  • 32
    • 34347260332 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2007 clinical practice guideline update on the role of bisphosphonates in multiple myeloma
    • Kyle RA, Yee GC, Somerfield MR et al (2007). American Society of Clinical Oncology 2007 clinical practice guideline update on the role of bisphosphonates in multiple myeloma. J Clin Oncol 25: 2464 2472.
    • (2007) J Clin Oncol , vol.25 , pp. 2464-2472
    • Kyle, R.A.1    Yee, G.C.2    Somerfield, M.R.3
  • 33
    • 0026646339 scopus 로고
    • Randomised, placebo-controlled multicentre trial of clodronate in multiple myeloma. Finnish Leukaemia Group
    • Lahtinen R, Laakso M, Palva I, Virkkunen P, Elomaa I (1992). Randomised, placebo-controlled multicentre trial of clodronate in multiple myeloma. Finnish Leukaemia Group. Lancet 340: 1049 1052.
    • (1992) Lancet , vol.340 , pp. 1049-1052
    • Lahtinen, R.1    Laakso, M.2    Palva, I.3    Virkkunen, P.4    Elomaa, I.5
  • 34
    • 57449109100 scopus 로고    scopus 로고
    • Influence of pre- and post-transplantation responses on outcome of patients with multiple myeloma: Sequential improvement of response and achievement of complete response are associated with longer survival
    • Lahuerta JJ, Mateos MV, Martinez-Lopez J et al (2008). Influence of pre- and post-transplantation responses on outcome of patients with multiple myeloma: sequential improvement of response and achievement of complete response are associated with longer survival. J Clin Oncol 26: 5775 5782.
    • (2008) J Clin Oncol , vol.26 , pp. 5775-5782
    • Lahuerta, J.J.1    Mateos, M.V.2    Martinez-Lopez, J.3
  • 35
    • 42149184112 scopus 로고    scopus 로고
    • Inhibition of oral mucosal cell wound healing by bisphosphonates
    • Landesberg R, Cozin M, Cremers S et al (2008). Inhibition of oral mucosal cell wound healing by bisphosphonates. J Oral Maxillofac Surg 66: 839 847.
    • (2008) J Oral Maxillofac Surg , vol.66 , pp. 839-847
    • Landesberg, R.1    Cozin, M.2    Cremers, S.3
  • 36
    • 57349138489 scopus 로고    scopus 로고
    • Bisphosphonate-induced osteonecrosis of the jaws, bone markers, and a hypothesized candidate gene
    • Lehrer S, Montazem A, Ramanathan L et al (2009). Bisphosphonate-induced osteonecrosis of the jaws, bone markers, and a hypothesized candidate gene. J Oral Maxillofac Surg 67: 159 161.
    • (2009) J Oral Maxillofac Surg , vol.67 , pp. 159-161
    • Lehrer, S.1    Montazem, A.2    Ramanathan, L.3
  • 37
    • 34248648455 scopus 로고    scopus 로고
    • Intronic microRNA: Discovery and biological implications
    • Li SC, Tang P, Lin WC (2007). Intronic microRNA: discovery and biological implications. DNA Cell Biol 26: 195 207.
    • (2007) DNA Cell Biol , vol.26 , pp. 195-207
    • Li, S.C.1    Tang, P.2    Lin, W.C.3
  • 38
    • 0031977199 scopus 로고    scopus 로고
    • Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
    • Luckman SP, Hughes DE, Coxon FP, Graham R, Russell G, Rogers MJ (1998). Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. J Bone Miner Res 13: 581 589.
    • (1998) J Bone Miner Res , vol.13 , pp. 581-589
    • Luckman, S.P.1    Hughes, D.E.2    Coxon, F.P.3    Graham, R.4    Russell, G.5    Rogers, M.J.6
  • 39
    • 0042861578 scopus 로고    scopus 로고
    • Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic
    • Marx RE (2003). Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg 61: 1115 1117.
    • (2003) J Oral Maxillofac Surg , vol.61 , pp. 1115-1117
    • Marx, R.E.1
  • 40
    • 27344453813 scopus 로고    scopus 로고
    • Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: Risk factors, recognition, prevention, and treatment
    • Marx RE, Sawatari Y, Fortin M, Broumand V (2005). Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg 63: 1567 1575.
    • (2005) J Oral Maxillofac Surg , vol.63 , pp. 1567-1575
    • Marx, R.E.1    Sawatari, Y.2    Fortin, M.3    Broumand, V.4
  • 41
    • 0030227986 scopus 로고    scopus 로고
    • Comparison of the distribution of 3H-alendronate and 3H-etidronate in rat and mouse bones
    • Masarachia P, Weinreb M, Balena R, Rodan GA (1996). Comparison of the distribution of 3H-alendronate and 3H-etidronate in rat and mouse bones. Bone 19: 281 290.
    • (1996) Bone , vol.19 , pp. 281-290
    • Masarachia, P.1    Weinreb, M.2    Balena, R.3    Rodan, G.A.4
  • 42
    • 0031911183 scopus 로고    scopus 로고
    • A randomized trial of the effect of clodronate on skeletal morbidity in multiple myeloma. MRC Working Party on Leukaemia in Adults
    • McCloskey EV, MacLennan IC, Drayson MT, Chapman C, Dunn J, Kanis JA (1998). A randomized trial of the effect of clodronate on skeletal morbidity in multiple myeloma. MRC Working Party on Leukaemia in Adults. Br J Haematol 100: 317 325.
    • (1998) Br J Haematol , vol.100 , pp. 317-325
    • McCloskey, E.V.1    MacLennan, I.C.2    Drayson, M.T.3    Chapman, C.4    Dunn, J.5    Kanis, J.A.6
  • 43
    • 34147116398 scopus 로고    scopus 로고
    • Bisphosphonate complications including osteonecrosis of the jaw
    • 515
    • Mehrotra B, Ruggiero S (2006). Bisphosphonate complications including osteonecrosis of the jaw. Hematology Am Soc Hematol Educ Program 1: 356 360, 515.
    • (2006) Hematology Am Soc Hematol Educ Program , vol.1 , pp. 356-360
    • Mehrotra, B.1    Ruggiero, S.2
  • 44
    • 0025215416 scopus 로고
    • Long-term effects of parenteral dichloromethylene bisphosphonate (CL2MBP) on bone disease of myeloma patients treated with chemotherapy
    • Merlini G, Parrinello GA, Piccinini L et al (1990). Long-term effects of parenteral dichloromethylene bisphosphonate (CL2MBP) on bone disease of myeloma patients treated with chemotherapy. Hematol Oncol 8: 23 30.
    • (1990) Hematol Oncol , vol.8 , pp. 23-30
    • Merlini, G.1    Parrinello, G.A.2    Piccinini, L.3
  • 45
    • 34247218044 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: A review of 35 cases and an evaluation of its frequency in multiple myeloma patients
    • Pozzi S, Marcheselli R, Sacchi S et al (2007). Bisphosphonate-associated osteonecrosis of the jaw: a review of 35 cases and an evaluation of its frequency in multiple myeloma patients. Leuk Lymphoma 48: 56 64.
    • (2007) Leuk Lymphoma , vol.48 , pp. 56-64
    • Pozzi, S.1    Marcheselli, R.2    Sacchi, S.3
  • 46
    • 42249086269 scopus 로고    scopus 로고
    • Clinical, radiographic, and biochemical characterization of multiple myeloma patients with osteonecrosis of the jaw
    • Raje N, Woo SB, Hande K et al (2008). Clinical, radiographic, and biochemical characterization of multiple myeloma patients with osteonecrosis of the jaw. Clin Cancer Res 14: 2387 2395.
    • (2008) Clin Cancer Res , vol.14 , pp. 2387-2395
    • Raje, N.1    Woo, S.B.2    Hande, K.3
  • 47
    • 0035463593 scopus 로고    scopus 로고
    • Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: A phase III, double-blind, comparative trial
    • Rosen LS, Gordon D, Kaminski M et al (2001). Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: a phase III, double-blind, comparative trial. Cancer J 7: 377 387.
    • (2001) Cancer J , vol.7 , pp. 377-387
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 48
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M et al (2003). Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer 98: 1735 1744.
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 49
    • 36549026045 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws and bisphosphonate therapy
    • Ruggiero SL, Drew SJ (2007). Osteonecrosis of the jaws and bisphosphonate therapy. J Dent Res 86: 1013 1021.
    • (2007) J Dent Res , vol.86 , pp. 1013-1021
    • Ruggiero, S.L.1    Drew, S.J.2
  • 50
    • 2142817155 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws associated with the use of bisphosphonates: A review of 63 cases
    • Ruggiero SL, Mehrotra B, Rosenberg TJ, Engroff SL (2004). Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. J Oral Maxillofac Surg 62: 527 534.
    • (2004) J Oral Maxillofac Surg , vol.62 , pp. 527-534
    • Ruggiero, S.L.1    Mehrotra, B.2    Rosenberg, T.J.3    Engroff, S.L.4
  • 51
    • 33748751877 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw: Background and guidelines for diagnosis, staging and management
    • Ruggiero SL, Fantasia J, Carlson E (2006). Bisphosphonate-related osteonecrosis of the jaw: background and guidelines for diagnosis, staging and management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102: 433 441.
    • (2006) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.102 , pp. 433-441
    • Ruggiero, S.L.1    Fantasia, J.2    Carlson, E.3
  • 52
    • 36549072502 scopus 로고    scopus 로고
    • Bisphosphonates: An update on mechanisms of action and how these relate to clinical efficacy
    • Russell RG, Xia Z, Dunford JE et al (2007). Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. Ann N Y Acad Sci 1117: 209 257.
    • (2007) Ann N Y Acad Sci , vol.1117 , pp. 209-257
    • Russell, R.G.1    Xia, Z.2    Dunford, J.E.3
  • 53
    • 10744227993 scopus 로고    scopus 로고
    • Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients
    • Santini D, Vincenzi B, Dicuonzo G et al (2003). Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients. Clin Cancer Res 9: 2893 2897.
    • (2003) Clin Cancer Res , vol.9 , pp. 2893-2897
    • Santini, D.1    Vincenzi, B.2    Dicuonzo, G.3
  • 54
    • 53449093633 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: A genome-wide single nucleotide polymorphism analysis
    • Sarasquete ME, Garcia-Sanz R, Marin L et al (2008). Bisphosphonate- related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis. Blood 112: 2709 2712.
    • (2008) Blood , vol.112 , pp. 2709-2712
    • Sarasquete, M.E.1    Garcia-Sanz, R.2    Marin, L.3
  • 55
    • 58849116790 scopus 로고    scopus 로고
    • Effect of zoledronic acid on oral fibroblasts and epithelial cells: A potential mechanism of bisphosphonate-associated osteonecrosis
    • Scheper MA, Badros A, Chaisuparat R, Cullen KJ, Meiller TF (2009). Effect of zoledronic acid on oral fibroblasts and epithelial cells: a potential mechanism of bisphosphonate-associated osteonecrosis. Br J Haematol 144: 667 676.
    • (2009) Br J Haematol , vol.144 , pp. 667-676
    • Scheper, M.A.1    Badros, A.2    Chaisuparat, R.3    Cullen, K.J.4    Meiller, T.F.5
  • 56
    • 0020031043 scopus 로고
    • Osteonecrosis of the jaws: A complication of cancer chemotherapy
    • Schwartz HC (1982). Osteonecrosis of the jaws: a complication of cancer chemotherapy. Head Neck Surg 4: 251 253.
    • (1982) Head Neck Surg , vol.4 , pp. 251-253
    • Schwartz, H.C.1
  • 57
    • 13744250353 scopus 로고    scopus 로고
    • Clinical practice. Hypercalcemia associated with cancer
    • Stewart AF (2005). Clinical practice. Hypercalcemia associated with cancer. N Engl J Med 352: 373 379.
    • (2005) N Engl J Med , vol.352 , pp. 373-379
    • Stewart, A.F.1
  • 58
    • 69449108135 scopus 로고    scopus 로고
    • The use of bisphosphonates in multiple myeloma: Recommendations of an expert panel on behalf of the European Myeloma Network
    • in press
    • Terpos E, Sezer O, Croucher P et al (2009). The use of bisphosphonates in multiple myeloma: Recommendations of an expert panel on behalf of the European Myeloma Network. Ann Oncol (in press).
    • (2009) Ann Oncol
    • Terpos, E.1    Sezer, O.2    Croucher, P.3
  • 59
    • 38449099944 scopus 로고    scopus 로고
    • Role of the cholesterol biosynthetic pathway in osteoblastic differentiation
    • Viccica G, Vignali E, Marcocci C (2007). Role of the cholesterol biosynthetic pathway in osteoblastic differentiation. J Endocrinol Invest 30: 8 12.
    • (2007) J Endocrinol Invest , vol.30 , pp. 8-12
    • Viccica, G.1    Vignali, E.2    Marcocci, C.3
  • 60
    • 0041358697 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws associated with cancer chemotherapy
    • Wang J, Goodger NM, Pogrel MA (2003). Osteonecrosis of the jaws associated with cancer chemotherapy. J Oral Maxillofac Surg 61: 1104 1107.
    • (2003) J Oral Maxillofac Surg , vol.61 , pp. 1104-1107
    • Wang, J.1    Goodger, N.M.2    Pogrel, M.A.3
  • 61
    • 40749111524 scopus 로고    scopus 로고
    • Zoledronate, smoking, and obesity are strong risk factors for osteonecrosis of the jaw: A case-control study
    • Wessel JH, Dodson TB, Zavras AI (2008). Zoledronate, smoking, and obesity are strong risk factors for osteonecrosis of the jaw: a case-control study. J Oral Maxillofac Surg 66: 625 631.
    • (2008) J Oral Maxillofac Surg , vol.66 , pp. 625-631
    • Wessel, J.H.1    Dodson, T.B.2    Zavras, A.I.3
  • 62
    • 0036721078 scopus 로고    scopus 로고
    • Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid
    • Wood J, Bonjean K, Ruetz S et al (2002). Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid. J Pharmacol Exp Ther 302: 1055 1061.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 1055-1061
    • Wood, J.1    Bonjean, K.2    Ruetz, S.3
  • 63
    • 33747426633 scopus 로고    scopus 로고
    • Incidence, risk factors and management of osteonecrosis of the jaw in patients with multiple myeloma: A single-centre experience in 303 patients
    • Zervas K, Verrou E, Teleioudis Z et al (2006). Incidence, risk factors and management of osteonecrosis of the jaw in patients with multiple myeloma: a single-centre experience in 303 patients. Br J Haematol 134: 620 623.
    • (2006) Br J Haematol , vol.134 , pp. 620-623
    • Zervas, K.1    Verrou, E.2    Teleioudis, Z.3
  • 64
    • 0029898894 scopus 로고    scopus 로고
    • Protein prenylation: Molecular mechanisms and functional consequences
    • Zhang FL, Casey PJ (1996). Protein prenylation: molecular mechanisms and functional consequences. Annu Rev Biochem 65: 241 269.
    • (1996) Annu Rev Biochem , vol.65 , pp. 241-269
    • Zhang, F.L.1    Casey, P.J.2


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