A meta-analysis and systematic review on the effect of probiotics in acute diarrhea

Inflammation and Allergy - Drug Targets

Volumn 11, Issue 1, 2012, Pages 3-14

  Salari, Pooneh ^a   Nikfar, Shekoufeh ^b   Abdollahi, Mohammad ^c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Clostridium difficile; Diarrhea; Meta analysis; Probiotics; Systematic review

Indexed keywords

ANTIINFECTIVE AGENT; METRONIDAZOLE; PLACEBO; PROBIOTIC AGENT;

ACUTE DIARRHEA; AMEBIASIS; BACILLUS PUMILUS; BIFIDOBACTERIUM BREVE; BIFIDOBACTERIUM LONGUM; CLINICAL TRIAL (TOPIC); CLOSTRIDIUM BUTYRICUM; CLOSTRIDIUM DIFFICILE; DISEASE DURATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ENTERITIS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FECES; FEVER; HEADACHE; HOSPITALIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS CASEI; LACTOBACILLUS PARACASEI; LACTOBACILLUS REUTERI; LACTOBACILLUS RHAMNOSUS; MEDICAL RECORD REVIEW; META ANALYSIS; PAIN; QUALITY OF LIFE; RADIATION EXPOSURE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SACCHAROMYCES BOULARDII; STREPTOCOCCUS THERMOPHILUS; SYSTEMATIC REVIEW; VOMITING;

EID: 84855826006     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152812798889394     Document Type: Review

References (70)

1. Anonymous. http://www.who.int/mediacentre/factsheets/fs330/en/ index.html
2. Rahimi, R.; Nikfar, S.; Rezaie, A.; Abdollahi, M. A meta-analysis of the benefit of probiotics in maintaining remission of human ulcerative colitis: evidence for prevention of disease relapse and maintenance of remission. Arch. Med. Sci., 2008, 4(2), 185-190.
3. Elahi, B.; Nikfar, S.; Derakhshani, S.; Vafaie, M.; Abdollahi, M. On the benefit of probiotics in the management of pouchitis in patients underwent ileal pouch anal anastomosis: a meta-analysis of controlled clinical trials. Dig. Dis. Sci., 2007, 53, 1278-1284.
4. Nikfar, S.; Darvish-Damavandi, M.; Abdollahi, M. A review and meta-analysis of the efficacy of antibiotics and probiotics in management of pouchitis. Int. J. Pharmacol., 2010, 6(6), 826-835.
5. Rahimi, R.; Nikfar, S.; Rahimi, F.; Elahi, B.; Derakhshani, S.; Vafaie, M.; Abdollahi, M. A meta-analysis on the efficacy of probiotics for maintenance of remission and prevention of clinical and endoscopic relapse in Crohn's disease. Di. g Dis. Sci., 2008, 53(9), 2524-2531.
6. Nikfar, S.; Rahimi, R.; Rahimi, F.; Derakhshani, S.; Abdollahi, M. Efficacy of probiotics in irritable bowel syndrome: a meta-analysis of randomized, controlled trials. Dis. Colon. Rectum., 2008, 51(12), 1775-1780.
7. Ohland, CL.; MacNaughton, W.K. Probiotic bacteria and intestinal epithelial barrier function. Am. J. Physiol. Gastrointest. Liver Physiol., 2010, 298, G807-G819.
8. Jadad, A.R.; Moore, R.A.; Carroll, D.; Jenkinson, C.; Reynolds, D.J.; Gavaghan, D.J.; McQuay, H.J. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control. Clin. Trials., 1996, 17, 1-12.
9. Chen, C.C.; Kong, M.S.; Lai, M.W.; Chao, H.C.; Chang, K.W.; Chen, S.Y.; Huang, Y.C.; Chiu, C.H.; Li, W.C.; Lin, P.Y.; Chen, C.J.; Li, T.Y. Probiotics have clinical microbiologic and immunologic efficacy in acute infectious diarrhea. Pediatr. Infect. Dis. J., 2010, 29, 135-138.
10. Moal, V.L.L.; Sarrazin-Davila, L.E.; Servin, A.L. An experimental study and a randomized double-blind placebo-controlled clinical trial to evaluate the antisecretory activity of Lactobacillus acidophilus, strain LB against nonrotavirus diarrhea. Pediatrics., 2007, 120, e795.
11. Henker, J.; Laas, M.; Blokhin, B.M.; Bolbot, Y.K.; Maydannik, V.G.; Elze, M.; Wolff, C.; Schulze, J. The probiotic Escherichia coli, strain Nissle 1917(EcN) stops acute diarrhea in infants and toddlers. Eur. J. Pediatr., 2007, 166, 311-318.
12. Szymanski, H.; Pejcz, J.; Jawien, M.; Chmielarczyks, A.; Strus, M.; Heczko, P.B. Treatment of acute infectious diarrhea in infants and children with a mixture of three Lactobacillus rhamnosus, starins-a randomized double-blind placebo-controlled trial. Aliment. Pharmacol. Ther., 2006, 23, 247-253.
13. Billoo, A.G.; Memon, M.A.; Khaskheli, S.A.; Murtaza, G.; Iqbal, K.; Saeed Shekhani, M.; Siddiqi, A.Q. Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhea. World J. Gastroenterol., 2006, 12(28), 4557-4560.
14. Sarker, S.A.; Sultana, S.; Fuchs, G.J.; Alam, N.H.; Azim, T.; Brüssow, H.; Hammarström, L. Lactobacillus paracasei, strain ST11 has no effect on rotavirus but ameliorates the outcome of nonrotavirus diarrhea in children from Bangladesh. Pediatrics, 2005, 116, e221.
15. Salazar-Lindo, E.; Miranda-Langschwager, P.M.; Campos-Sanchez, M.; Chea-Woo, E.; Bradley Sack, R. Lactobacillus casei, strain GG in the treatment of infants with acute watery diarrhea: a randomized double-blind placebo controlled clinical trial [ISRCTN67363048]. BMC Pediatr., 2004, 4, 18.
16. Teran, C.G.; Teran-Escalera, C.N.; Villarroel, P. Nitazoxanide vs, probiotics for the treatment of acute rotavirus diarrhea in children: a randomized single-blind controlled trial in Bolivian children. Int. J. Infect. Dis., 2009, 13, 518-523.
17. Narayanappa, D. Randomized double blinded controlled trial to evaluate the efficacy and safety of Bifilac in patients with acute viral diarrhea. Indian J. Pediatr., 2008, 75(7), 709-713.
18. Basu, S.; Chatterjee, M.; Ganguly, S.; Chandra, P.K. Efficacy of Lactobacillus rhamnosus, GG in acute watery diarrhea of Indian children: a randomized controlled trial. J. Pediatr. Child Health, 2007, 43(12), 837-842.
19. Villarruel, G.; Rubio, D.M.; Lopez, F.; Cintoni, J.; Gurevech, R.; Romero, G.; Vandenplas, Y. Saccharomyces boulardii, in acute childhood diarrhea: a randomized placebo-controlled study. Acta. Pediatr., 2007, 96, 538-541.
20. Khanna, V.; Alam, S.; Malik, A.; Malik, A. Efficacy of tyndalized Lactobacillus acidophilus, in acute diarrhea. Indian J. Pediatr., 2005, 72(11), 935-938.
21. Kurugöl, Z.; Koturǧlu, G. Effects of Saccharomyces boulardii, in children with acute diarrhea. Acta. Pediatr., 2005, 94, 44-47.
22. Thibault, H.; Aubert-Jacquin, C.; Goulet, O. Effects of long-term consumption of a fermented infant formula (with Bifidobacterium breve, c50 and Streptococcus thermophilus, 065) on acute diarrhea in healthy infants. J. Pediatr.; Gastroenterol. Nutr., 2004, 39, 147-152.
23. Mao, M.; Yu, T.; Xiong, Y.; Wang, Z.; Liu, H.; Gotteland, M.; Brunser, O. Effect of a lactose-free milk formula supplemented with bifidobacteria and streptococci on the recovery from acute diarrhea. Asia Pac. J. Clin. Nutr., 2008, 17(1), 30-34.
24. Agustina, R.; Lukito, W.; Firmansyah, A.; Suhardjo, H.N.; Murniati, D.; Bindels, J. The effect of early nutritional supplementation with a mixture of probiotic, prebiotic fiber and micronutrients in infants with acute diarrhea in Indonesia. Asia Pac. J. Clin. Nutr., 2007, 16(3), 435-442.
25. Gaon, D.; Garcia, H.; Winter, L.; Rodríguez, N.; Quintás, R.; González, S.N.; Oliver, G. Effect of lactobacillus and Saccharomyces noulardii on persistent diarrhea in children. Medicina, 2003, 63, 293-298.
26. Rosenfeldt, V.; Michaelsen, K. F;, Jakobsen, M.; Larsen, C.N.; Møller, P.L.; Pedersen, P.; Tvede, M.; Weyrehter, H.; Valerius, N.H.; Paerregaard, A. Effect of probiotic Lactobacillus starins in young children hospitalized with acute diarrhea. Pediatr. Infect. Dis. J., 2002, 21, 411-416.
27. Basu, S.; Chattaerjee, M.; Ganguly, S.; Chandra, P.K. Effect of Lactobacillus rhamnosus, GG in persistent diarrhea in Indian children. J. Clin. Gastroenterol., 2007, 41, 756-760.
28. Pashapour, N.; Iou, S.G. Evaluation of yogurt effect on acute diarrhea in 6-24-month-old hospitalized infants. Turk. J. Pediatr., 2006, 48(2), 115-118.
29. Szajewska, H.; Skórka, A.; Dylag, M. Meta-analysis: Saccharomyces boulardii, for treating acute diarrhea in children. Aliment. Pharmacol. Ther., 2006, 25, 257-264.
30. Van Niel, C.W.; Feudtner, C.; Garrison, M.M.; Christakis, D.A. Lactobacillus therapy for acute infectious diarrhea in children: a meta-analysis. Pediatrics, 2002, 109, 678.
31. Huang, J.S.; Bousvaros, A.; Lee, J.W.; Diaz, A.; Davidson, E.J. Efficacy of probiotic use in acute diarrhea in children. A metaanalysis. Dig. Dis. Sci., 2002, 47(11), 2625-2634.
32. Grandy, G.; Medina, M.; Soria, R.; Terán, C.G.; Araya, M. Probiotics in the treatment of acute rotavirus diarrhea. A randomized double-blind controlled trial using two different probiotic preparations in Bolivian children. BMC Infect. Dis., 2010, 10, 253.
33. Sazawal, S.; Dhingra, U.; Hiremath, G.; Sarkar, A.; Dhingra, P.; Dutta, A.; Verma, P.; Menon, V.P.; Black, R.E. Prebiotic and probiotic fortified milk in prevention of morbidities among children: community-based randomized double-blind controlled trial. PLoS One, 2010, 5(8), e12164.
34. Misra, S.; Sabui, T.K.; Pal, N.K. A randomized controlled trial to evaluate the efficacy of Lactobacillus GG in infantile diarrhea. J. Pediatr., 2009, 155, 129-132.
35. Lei, V.; Friis, H.; Michaelsen, K.F. Spontaneously fermented millet product as a natural probiotic treatment for diarrhea in young children: an intervention study in Northern Ghana. Int. J. Food Microbiol., 2006, 110, 246-253.
36. Grossi, E.; Buresta, R.; Abbiati, R.; Cerutti, R. Clinical trial on the efficacy of a new symbiotic formulation Flortec in patients with acute diarrhea. A multicenter randomized study in primary care. J. Clin. Gastroenterol., 2010, 44, S35-S41.
37. Xiao, S.D.; Zhang, D.Z.; Lu, H.; Jiang, S.H.; Liu, H.Y.; Wang, G.S.; Xu, G.M.; Zhang, Z.B.; Lin, G.J.; Wang, G.L. Multicenter randomized controlled trial of heat-killed Lactobacillus acidophilus, LB in patients with chronic diarrhea. Adv. Ther., 2003, 20(5), 253-260.
38. Margreiter, M.; Ludl, K.; Phleps, W.; Kaehler, S.T. Therapeutic value of a Lactobacillus gasseri, and Bifidobacterium longum, fixed bacterium combination in acute diarrhea: a randomized doubleblind controlled trial. Int. J. Clin. Pharmacol. Ther., 2006, 44(5), 207-215.
39. Briand, V.; Buffet, P.; Genty, S.; Lacombe, K.; Godineau, N.; Salomon, J.; Vandemelbrouck, E.; Ralaimazava, P.; Goujon, C.; Matheron, S.; Fontanet, A.; Bouchaud, O. Absence of efficacy of nonviable Lactobacillus acidophilus, for the prevention of travelers diarrhea: a randomized double-blind controlled study. Clin. Infect. Dis., 2006, 43, 1170-1175.
40. Pereg, D.; Kimhi, O.; Tirosh, A.; Orr, N.; Kayouf, R.; Lishner, M. The effect of fermented yogurt on the prevention of diarrhea in a healthy adult population. Am. J. Infect. Control., 2005, 33, 122-125.
41. Zaharoni, H.; Rimon, E.; Vardi, H.; Friger, M.; Bolotin, A.; Shahar, D.R. Probiotics improve bowel movements in hospitalized elderly patients-the PROAGE study. J. Nutr. Health Aging, 2011, 15(3), 215-220.
42. Mansour-Ghanaei, F.; Dehbashi, N.; Yazdanparast, K.; Shafaghi, A. Efficacy od Saccharomyces boulardii, with antibiotics in acute amoebiasis. World J. Gastroenterol., 2003, 9(8), 1832-1833.
43. Dinleyci, E.C.; Eren, M.; Yargic, Z.A.; Dogan, N.; Vandenplas, Y. Clinical efficacy of Saccharomyces boulardii, and metronidazole compared to metronidazole alone in children with acute bloody diarrhea caused by amebiasis: a prospective randomized open label study. Am. J. Trop. Med. Hyg., 2009, 80(6), 953-955.
44. Savas-Erdeve, S.; Gökay, S.; Dallar, Y. Efficacy and safety of Saccharomyces boulardii, in amebiasis-associated diarrhea in children. Turk. J. Pediatr., 2009, 51(3), 220-224.
45. Fekety, R. Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis. American College of Gastroenterology, Practice Parameters Committee. Am. J. Gastroenterol., 1997, 92, 739-750.
46. Wilcox, M.H. Treatment of Clostridium difficile, infection. J. Antimicrob. Chemother., 1998, 41(Suppl C), 41-46.
47. Biller, J.A.; Katz, A.J.; Flores, A.F.; Buie, T.M.; Gorbach, S.L. Treatment of recurrent Clostridium difficile, colitis with Lactobacillus GG. J. Pediatr. Gastroenterol. Nutr., 1995, 21, 224-226.
48. Bennet, R.; Gorbach, S.; Goldin, B. Treatment of relapsing C. difficile diarrhea with Lactobacillus GG. Nutr. Today, 1996, 31(Suppl), 35-38S.
49. Surawicz, C.M.; McFarland, L.V.; Greenberg, R.N.; Rubin, M.; Fekety, R.; Mulligan, M.E.; Garcia, R.J.; Brandmarker, S.; Bowen, K.; Borjal, D.; Elmer, G.M. The search for a better treatment for recurrent Clostridium difficile, disease: use of high-dose vancomycin combined with Saccharomyces boulardii. Clin. Infect. Dis., 2000, 31, 1012-1017.
50. Wullt, M.; Hagslatt, M.L.J.; Odenholt, I. Lactobacillus plantarum, 299v for the treatment of recurrent clostridium difficile-associated diarrhea: a double-blind, placebo-controlled trial. Scand. J. Infect. Dis., 2003, 35, 365-367.
51. Plummer, S.; Weaver, M.A.; Harris, J.C.; Dee, P.; Hunter. J. Clostridium difficile, pilot study: effects of probiotic supplementation on the incidence of C. difficile diarrhea. Int. Microbiol., 2004, 7, 59-62.
52. Naaber, P.; Smidt, I.; Štšepetova, J.; Brilene, T.; Annuk, H.; Mikelsaar, M. Inhibition of Clostridium difficile, strains by intestinal Lactobacillus species. J. Med. Microbiol., 2004, 53, 551-554.
53. Framm, S.R.; Soave, R. Agents of diarrhea. Med. Clin. North Am., 1997, 81, 427-447.
54. Smith, P.D.; Quinn, T.C.; Strober, W.; Janoff, E.N.; Masur, H. Gastrointestinal infections in AIDS. Ann. Intern. Med., 1992, 116, 63-77.
55. Navin, T.; Weber, R.; Vugia, D.; Rimland, D.; Roberts, J.M.; Addiss, D.G.; Visvesvara, G. S.; Wahlquist, S.P.; Hogan, S.E.; Gallagher, L.E.; Juranek, D.D.; Schwartz, D.A.; Wilcox, C.M.; Stewart, J.M.; Thompson, S.E. 3rd, Bryan, R.T. Declining CD4+ T Lymphocyte counts are associated with increased risk of enteric parasitosis and chronic diarrhea: results of a 3-year longitudinal study. J. Acquir. Immune. Defic. Syndr. Hum. Retrovirol., 1999, 20, 154-159.
56. Weber, R.; Ledergerber, B.; Zbinden, R.; Altwegg, M.; Pfyffer, G.E.; Spycher, M.A.; Briner, J.; Kaiser, L.; Opravil, M.; Meyenberger, C.; Flepp, M. Enteric infections and diarrhea in human immunodeficiency virus-infected persons: prospective community-based cohort study. Swiss HIV Cohort Study. Arch. Intern. Med., 1999, 159, 1473-1480.
57. Salminen, M.K.; Tynkkynen, S.; Rautelin, H.; Poussa, T.; Saxelin, M.; Ristola, M.; Valtonene, V.; Järvinen, A. The efficacy and safety of probiotic Lactobacillus rhamnosus, GG on prolonged noninfectious diarrhea in HIV patients on antiretroviral therapy: a randomized placebo-controlled crossover study. HIV. Clin. Trials, 2004, 5(4), 183-191.
58. Trois, L.; Cardoso, E.M.; Miura, E. Use of probiotics in HIVinfected children: a randomized double-blind controlled study. J. Trop. Pediatr., 2008, 54(1), 19-24.
59. Anukam, K.C.; Osazuwa, E.O.; Osadolor, H.B.; Bruce, A.W.; Reid, G. Yogurt containing probiotic Lactobacillus rhamnosus, GR-1 and L. reuteri RC-14 helps resolve moderate diarrhea and increases CD4 count in HIV/AIDS patients. J. Clin. Gastroenterol., 2008, 42, 239-243.
60. Urbancsek, H.; Kazar, T.; Mezes, I.; Neumann, K. Results of a double-blind randomized study to evaluate the efficacy and safety of antibiophilus® in patients with radiation-induced diarrhea. Eur. J. Gastroenterol. Hepatol., 2001, 13(4), 391-396.
61. Delia, P.; Sansotta, G.; Donato, V.; Forsina, P.; Messina, G.; De Renzis, C.; Famularo, G. Use of probiotics for prevention of radiation-induced diarrhea. World J. Gastroenterol., 2007, 13(6), 912-915.
62. Giralt, J.; Regadera, J.P.; Verges, R.; Romero, J.; de la Fuente, I.; Biete, A.; Villoria, J.; Cobo, J.M.; Guarner, F. Effects of probiotic Lactobacillus casei, DN-114001 in prevention of radiation-induced diarrhea: results from multicenter randomized placebo-controlled nutritional trial. Int. J. Radiat. Oncol. Biol. Phys., 2008, 71(4), 1213-1239.
63. Österlund, P.; Ruotsalainen, T.; Korpela, R.; Saxelin, M.; Ollus, A.; Valta, P.; Kouri, M.; Elomaa, I.; Joensuu, H. Lactobacillus supplementation for diarrhea related to chemotherapy of colorectal cancer: a randomized study. Br. J. Cancer, 2007, 97, 1028-1034.
64. Bassetti, S.; Frei, R.; Zimmarli, W. Fungemia with Saccharomyces cerevisiae after treatment with S. boulardii. Am. J. Med., 1998, 105, 71-72.
65. Rijnders, B.J.A.; Van Wijngaerden, E.; Verwaest, C.; Peetermans, W.E. Saccharomyces fungemia compli cating S. boulardii, treatment in a non-immunocompromised host. Intensive Care Med., 2000, 26, 825.
66. Zunic, P.; Lacotte, J.; Pegoix, M.; Buteux, G.; Leroy, G.; Mosquet, B.; Moulin, M. Saccharomyces boulardii, fungemia. Apropos of a case. Therapie, 1991, 46, 498-499.
67. Ghasemi-Niri, S.F., Abdolghaffari, A.H., Fallah-Benakohal, S., Hosseinpour-Feizi, M., Mahdaviani, P., Jamalifar, H., Baeeri, M., Dehghan, G., Abdollahi, M. On the benefit of whey-cultured Lactobacillus casei, in murine colitis. J. Physiol. Pharmacol., 2011, 62(3), 341-6.
68. Baghaei, A., Esmaily, H., Abdolghaffari, A.H., Baeeri, M., Gharibdoost, F., Abdollahi, M. Efficacy of Setarud (IMOD®), a novel drug with potent anti-toxic stress potential in rat inflammatory bowel disease and comparison with dexamethasone and infliximab. Indian J. Biochem. Biophys. 2010, 47, 219-226.
69. Nikfar, S., Mirfazaelian, H., Abdollahi, M. Efficacy and tolerability of immunoregulators and antibiotics in fistulizing Crohn's disease: A systematic review and meta-analysis of placebo-controlled trials. Curr. Pharm. Des. 2010, 16, 3684-3698.
70. Rezaie, A., Parker, R.D., Abdollahi, M. Oxidative stress and pathogenesis of inflammatory bowel disease: an epiphenomenon or the cause? Dig. Dis. Sci., 2007, 52(9), 2015-21.