Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis

American Journal of Gastroenterology

Volumn 92, Issue 5, 1997, Pages 739-750

  Fekety, Robert ^a  

^a UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM DIFFICILE; COLITIS; DIARRHEA; ENDOSCOPY; ENZYME IMMUNOASSAY; FECES MICROFLORA; HUMAN; INTESTINE MUCOSA; PATHOPHYSIOLOGY; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; SCREENING TEST; SHORT SURVEY; TREATMENT PLANNING;

ANTI-BACTERIAL AGENTS; CLOSTRIDIUM DIFFICILE; DIARRHEA; ENTEROCOLITIS, PSEUDOMEMBRANOUS; HUMANS; RECURRENCE;

EID: 0030969261     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (63)

1. Bartlett JG. Treatment of Clostridium difficile colitis. Gastroenterology 1985;89:1192-5.
2. Fekety R, Shah A. Diagnosis and treatment of C. difficile colitis. JAMA 1993;269:71-5.
3. Kelly CP, Pothoulakis C, LaMont JT. Clostridium difficile colitis. N Engl J Med 1994;330:257-62.
4. Fekety R. Antibiotic-associated colitis. In: Mandell G, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases, 4th ed. New York: Churchill Livingstone, 1996, pp 978-806.
5. Mitty RD, LaMont T. Clostridium difficile diarrhea: Pathogenesis, epidemiology, and treatment. Gastroenterologist 1994;2:61-9.
6. Bartlett JG. Clostridium difficile: History of its role as an enteric pathogen and the current state of knowledge about the organism. Clin Infect Dis 1994;18(suppl 4):S265-72.
7. Cudmore M, Silva J, Fekety R, et al. Clostridium difficile colitis associated with cancer chemotherapy. Arch Intern Med 1982;142: 333-5.
8. Johnson S, Gerding D. Clostridium difficile. In: Mayhall CG, ed. Hospital epidemiology and infection control. Baltimore: Williams & Wilkins, 1996, pp 399-408.
9. Riegler M, Sedivy R, Pothoulakis C, et al. Clostridium difficile toxin B is more potent than toxin A in damaging human colonic mucosa in vitro. J Clin Invest 1995;95:2004-11.
10. Qualman S, Petric M, Karmali M, et al. Clostridium difficile invasion and toxin circulation in fatal pediatric pseudomembranous colitis. Am J Clin Pathol 1990;94:410-6.
11. McFarland LV, Mulligan ME, Kwok RY, et al. Nosocomial acquisition of Clostridium difficile. N Engl J Med 1989;320:204-10.
12. Wilcox M. Cleaning up Clostridium difficile infection. Lancet 1996; 348:767-8.
13. Fekety R. Staphylococcal enterocolitis and diarrhea. In: Crossley K, Archer G, eds. Staphylococcal infections. New York: Churchill Livingstone, 1997.
14. Kim K-H, Fekety R, Batts DH, et al. Isolation of Clostridium difficile from the environment and contacts of patients with antibiotic-induced colitis. J Infect Dis 1981;143:42-50.
15. Medich DS, Lee KK, Simmons RL, et al. Laparotomy for fulminant pseudomembranous colitis. Arch Surg 1992;127:847-52.
16. Triadifopoulos G, Hailstone AE. Acute abdomen as presentation of pseudomembranous colitis. Gastroenterology 1991;100:685-91.
17. Tedesco FJ. Antibiotic-associated pseudomembranous colitis with negative proctosigmoidoscopic examination. Gastroenterology 1979; 77:295-7.
18. Gerding DM, Brazier JS. Optimal methods for identifying Clostridium difficile infections. Clin Infect Dis 1993;16(suppl 4):S439-42.
19. Martirosian G, Meisel-Mikolajczyk F, Stanczak J, et al. Toxigenicity of Clostridium difficile strains isolated in the surgical ward. Acta Microbiol Pol 1995;44:47-53.
20. Staneck JL, Weckbach LS, Allen SD, et al. Multicenter evaluation of four methods for Clostridium difficile detection: ImmunoCard C. difficile, cytotoxin assay, culture, and latex agglutination. J Clin Microbiol 1996;34:2718-21.
21. Barbut F, Kajzer C, Planas N, et al. Comparison of three enzyme immunoassays, a cytotoxicity assay, and toxigenic culture for diagnosis of Clostridium difficile-associated diarrhea. J Clin Microbiol 1993; 31:963-7.
22. Fekety R, Silva J, Kauffman C, et al. Treatment of antibiotic-associated Clostridium difficile colitis with oral vancomycin: Comparison of two dosage regimens. Am J Med 1989;86:15-9.
23. Lyerly DM, Barroso LA, Wilkins TD. Identification of the latex-test reactive protein of C. difficile as glutamate dehydrogenase. J Clin Microbiol 1988;29:2639-42.
24. George WL, Sutter VL, Citron D, et al. Selective and differential medium for isolation of Clostridium difficile. J Clin Microbiol 1979; 9:214-9.
25. Fekety R. Antibiotic-associated diarrhea and colitis. Curr Opin Infect Dis 1995;8:391-7.
26. Anglim A, Farr B. Nosocomial gastrointestinal infections. In: Mayhall CG, ed. Hospital epidemiology and infection control. Baltimore: Williams & Wilkins, 1966, pp 196-225.
27. Marx CE, Morris A, Wilson ML, et al. Fecal leukocytes in stool specimens submitted for Clostridium difficile toxin assay. Diagn Microbiol Infect Dis 1993;16:313-5.
28. Guerrant RL, Araiys V, Soares E, et al. Measurement of fecal lactoferrin as a marker of fecal leukocytes. J Clin Microbiol 1992;30: 1238-42.
29. Miller JR, Barrett LJ, Kotloff K, et al. A rapid test for infectious and inflammatory enteritis. Arch Intern Med 1994;154:2660-4.
30. Boland GW, Lee MJ, Cats A, et al. Pseudomembranous colitis: Diagnostic sensitivity of the abdominal plain radiograph. Clin Radiol 1994; 49:473-475.
31. Boland GW, Lee MJ, Cats AM, et al. Antibiotic-induced diarrhea: Specificity of abdominal CT for the diagnosis of Clostridium difficile disease. Radiology 1994;191:103-6.
32. Novak E, Lee JE, Seckman CE, et al. Unfavorable effect of atropine-diphenoxylate (Lomotil) therapy in lincomycin-caused diarrhea. JAMA 1976;235:1451.
33. Teasley DG, Gerding DN, Olson MN, et al. Prospective randomized trial of metronidazole versus vancomycin for the treatment of C. difficile associated diarrhea and colitis. Lancet 1983;2:1043-6.
34. Bolton RP, Culshaw MA. Fecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile. Gut 1986;183:1169-72.
35. Johnson S, Homann SR, Betten KM, et al. Treatment of asymptomatic Clostridium difficile carriers (fecal excretors) with vancomycin or oral metronidazole. Ann Intern Med 1992;117:297305.
36. Hospital Infection Control Advisory Committee. Recommendations for preventing the spread of vancomycin-resistant enterococci. Am J Infect Control 1995;23:87-94.
37. Fekety R. Unpublished data.
38. Tsutaoka B, Hansen J, Johnson D, et al. Antibiotic-associated pseudomembranous enteritis due to Clostridium difficile. Clin Infect Dis 1994;18:982-4.
39. Larkin S, Williams D, Osterholm M, et al. Toxic shock syndrome: Clinical, laboratory, and pathological findings in nine fatal cases. Ann Intern Med 1982;96:858-64.
40. Larkin S, Williams D, Osterholm M, et al. Toxic shock syndrome: Clinical, laboratory, and pathologic findings in nine fatal cases. Ann Intern Med 96;1992:858-97.
41. Takesue Y, Yokoyama T, Kodama T, et al. Toxin involvement in methicillin-resistant Staphylococcus aureus enteritis in gastroenterological surgery. Gastroenterol Jpn 1991;26:716-9.
42. Batts D, Silva J, Fekety R. Staphylococcal enterocolitis. In: Current chemotherapy and infectious diseases. Proceedings of the 11th ICC and the 19th ICAAC, Washington, D.C. American Society of Microbiology 1980:994-5.
43. Pasic M, Jost R, Carell T, et al. Intracolonic vancomycin for pseudomembranous colitis. N Engl J Med 1993;329:583 (letter).
44. Dudley MN, McLaughlin JC, Carrington J, et al. Oral bacitracin vs vancomycin therapy for Clostridium difficile-induced diarrhea. A randomized double blind trial. Arch Intern Med 1986;146:1101-4.
45. de Lalla F, Nicolin R, Rinaldi E, et al. Prospective study of oral teicoplanin versus oral vancomycin for therapy of pseudomembranous colitis and Clostridium difficile- associated diarrhea. Antimicrob Agents Chemother 1992;36:2192-6.
46. Kreutzer EW, Milligan FD. Treatment of antibiotic-associated pseudomembranous colitis with cholestyramine resin. Johns Hopkins Med J 1978;143:67-72.
47. Jobe B, Grasely A, Deveney K, et al. Clostridium difficile colitis: An increasing hospital-acquired illness. Am J Surg 1995;169:480-3.
48. Fekety R, McFarland LV, Surawicz CM, et al. Recurrent Clostridium difficile disease. Clin Infect Dis (in press).
49. Leung DY, Kelly CP, Boguniewicz M, et al. Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin. J Pediatr 1991;118:633-7.
50. Hassett J, Meyers S, McFarland L, et al. Recurrent Clostridium difficile infection in a patient with selective IgG1 deficiency treated with intravenous immune globulin and Saccharomyces boulardii Clin Infect Dis 1995;20(suppl 2):S266-8.
51. Onderdonk AB, Cisnoeros RL, Bartlett JG. Clostridium difficile in gnotobiotic mice. Infect Immun 1980;28:277-82.
52. Wilson K, Perini F. Role of competition for nutrients in suppression of Clostridium difficile by the colonic microflora. Infect Immun 1988; 56:2610-4.
53. Tedesco FJ. Treatment of recurrent antibiotic-associated pseudomembranous colitis. Am J Gastroenterol 1982;77:220-1.
54. Buggy BP, Fekety R, Silva J. Therapy of relapsing Clostridium difficile-associated diarrhea with the combination of vancomycin and rifampin. J Clin Gastroenterol 1987;9:155-9.
55. Gorbach SL. Successful treatment of relapsing Clostridium difficile colitis with Lactobacillus GG. Lancet 1987;2:1519.
56. Schwan A, Sjolins, Trottestam U, et al. Relapsing Clostridium difficile enterocolitis cured by rectal infusion of normal feces. Scand J Infect Dis 1984;16:211-5.
57. Tvede M, Rask-Madsen J. Bacteriotherapy for chronic relapsing Clostridium difficile diarrhoea in six patients. Lancet 1898;1:1156-60.
58. McFarland LV, Surawicz CM, Greenberg RN, et al. A randomized placebo-controlled trial of Saccharomyces boulardii in combination with standard antibiotics for Clostridium difficile disease. JAMA 1994; 271:1913-8.
59. Pothoulakis C, Kelly CP, Joshi MA, et al. Saccharomyces boulardii inhibits Clostridium difficile binding and enterotoxicity in rat ileum. Gastroenterology 1993;104:1108-15.
60. McFarland LV. Saccharomyces boulardii is not Saccharomyces cerevisiae. Clin Infect Dis 1996;22:200-1.
61. Warny M, Denie C, Delmee M, et al. Gamma globulin administration in relapsing Clostridium difficile induced pseudomembranous colitis with a defective antibody response to toxin A. Acta Clin Belg 1995; 50:36-9.
62. Johnson S, Gerding DN, Olson MM, et al. Prospective, controlled study of vinyl glove use to interrupt Clostridium difficile nosocomial transmission. Am J Med 1990;88:137-40.
63. Bettin K, Clabots C, Mathie P, et al. Effectiveness of liquid soap vs. chlorhexidine gluconate for the removal of Clostridium difficile from bare hands and gloved hands. Infect Control Hosp Epidemiol 1994; 15:697-702.