SCOPUS 정보 검색 플랫폼

Volumn 20, Issue 2, 2012, Pages 614-621

Novel inhibitors of surface layer processing in Clostridium difficile

(4) Tam Dang, T H a Fagan, Robert P a Fairweather, Neil F a Tate, Edward W a

a IMPERIAL COLLEGE LONDON (United Kingdom)

Author keywords

Activity based probe; Activity based protein profiling; Clostridium difficile; Protease inhibitor; Surface layer protein

Indexed keywords

BACTERIAL PROTEIN; CWP84 INHIBITOR; PAPAIN; PROTEIN CWP84; PROTEINASE INHIBITOR; SURFACE LAYER A PROTEIN; UNCLASSIFIED DRUG;

ACTIVITY BASED PROBE; ARTICLE; BACTERIAL CELL; CARBOXY TERMINAL SEQUENCE; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; DRUG DESIGN; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; IN VIVO STUDY; MOLECULAR PROBE; NONHUMAN; PROTEIN PROCESSING;

BACTERIAL PROTEINS; CLOSTRIDIUM DIFFICILE; CYSTEINE ENDOPEPTIDASES; HOST-PATHOGEN INTERACTIONS; PEPTIDES; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM DIFFICILE;

EID: 84855821826 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2011.06.042 Document Type: Article

Times cited : (8)

References (47)

1
- 0000795948
- O.T.E. Hall IC Am. J. Dis. Child. 49 1935 390
- (1935) Am. J. Dis. Child. , vol.49 , pp. 390
- Hall Ic, O.T.E.¹

2
- 55249105923
- C.P. Kelly, and J.T. LaMont N. Eng. J. Med. 359 2008 1932
- (2008) N. Eng. J. Med. , vol.359 , pp. 1932
- Kelly, C.P.¹ Lamont, J.T.²

3
- 67649391053
- M. Rupnik, M.H. Wilcox, and D.N. Gerding Nat. Rev. Microbiol. 7 2009 526
- (2009) Nat. Rev. Microbiol. , vol.7 , pp. 526
- Rupnik, M.¹ Wilcox, M.H.² Gerding, D.N.³

4
- 34247184821
- J.G. Bartlett J. Clin. Gastroenterol. 41 2007 S24
- (2007) J. Clin. Gastroenterol. , vol.41 , pp. 24
- Bartlett, J.G.¹

5
- 84855795326
- Thelestam, M.; Chaves-Olarte, E. Cytotoxic effects of the Clostridium difficile toxins, 2000.
- (2000) Cytotoxic Effects of the Clostridium Difficile Toxins
- Thelestam, M.¹ Chaves-Olarte, E.²

6
- 77957988127
- S.A. Kuehne, S.T. Cartman, J.T. Heap, M.L. Kelly, A. Cockayne, and N.P. Minton Nature 467 2010 711
- (2010) Nature , vol.467 , pp. 711
- Kuehne, S.A.¹ Cartman, S.T.² Heap, J.T.³ Kelly, M.L.⁴ Cockayne, A.⁵ Minton, N.P.⁶

7
- 33947260554
- T. Jank, T. Giesemann, and K. Aktories Glycobiology 17 2007 15R
- (2007) Glycobiology , vol.17
- Jank, T.¹ Giesemann, T.² Aktories, K.³

8
- 0034525733
- C. Pothoulakis Ann. N.Y. Acad. Sci. 915 2000 347
- (2000) Ann. N.Y. Acad. Sci. , vol.915 , pp. 347
- Pothoulakis, C.¹

9
- 0020003645
- N.M. Sullivan, S. Pellett, and T.D. Wilkins Infect. Immun. 35 1982 1032
- (1982) Infect. Immun. , vol.35 , pp. 1032
- Sullivan, N.M.¹ Pellett, S.² Wilkins, T.D.³

10
- 0025093524
- S.P. Borriello, H.A. Davies, S. Kamiya, P.J. Reed, and S. Seddon Rev. Infect. Dis. 12 1990 S185
- (1990) Rev. Infect. Dis. , vol.12 , pp. 185
- Borriello, S.P.¹ Davies, H.A.² Kamiya, S.³ Reed, P.J.⁴ Seddon, S.⁵

11
- 0028132771
- T. Karjalainen, M.C. Barc, A. Collignon, S. Trolle, H. Boureau, J. Cottelaffitte, and P. Bourlioux Infect. Immun. 62 1994 4347
- (1994) Infect. Immun. , vol.62 , pp. 4347
- Karjalainen, T.¹ Barc, M.C.² Collignon, A.³ Trolle, S.⁴ Boureau, H.⁵ Cottelaffitte, J.⁶ Bourlioux, P.⁷

12
- 0033817386
- M. Cerquetti, A. Molinari, A. Sebastianelli, M. Diociaiuti, R. Petruzzelli, C. Capo, and P. Mastrantonio Microb. Pathog. 28 2000 363
- (2000) Microb. Pathog. , vol.28 , pp. 363
- Cerquetti, M.¹ Molinari, A.² Sebastianelli, A.³ Diociaiuti, M.⁴ Petruzzelli, R.⁵ Capo, C.⁶ Mastrantonio, P.⁷

13
- 0021126857
- T. Kawata, A. Takeoka, K. Takumi, and K. Masuda FEMS Microbiol. Lett. 24 1984 323
- (1984) FEMS Microbiol. Lett. , vol.24 , pp. 323
- Kawata, T.¹ Takeoka, A.² Takumi, K.³ Masuda, K.⁴

14
- 0026035298
- A. Takeoka, K. Takumi, T. Koga, and T. Kawata J. Gen. Microbiol. 137 1991 261
- (1991) J. Gen. Microbiol. , vol.137 , pp. 261
- Takeoka, A.¹ Takumi, K.² Koga, T.³ Kawata, T.⁴

15
- 0034971793
- E. Calabi, S. Ward, B. Wren, T. Paxton, M. Panico, H. Morris, A. Dell, G. Dougan, and N. Fairweather Mol. Microbiol. 40 2001 1187
- (2001) Mol. Microbiol. , vol.40 , pp. 1187
- Calabi, E.¹ Ward, S.² Wren, B.³ Paxton, T.⁴ Panico, M.⁵ Morris, H.⁶ Dell, A.⁷ Dougan, G.⁸ Fairweather, N.⁹

16
- 0035077376
- A.-J. Waligora, C. Hennequin, P. Mullany, P. Bourlioux, A. Collignon, and T. Karjalainen Infect. Immun. 69 2001 2144
- (2001) Infect. Immun. , vol.69 , pp. 2144
- Waligora, A.-J.¹ Hennequin, C.² Mullany, P.³ Bourlioux, P.⁴ Collignon, A.⁵ Karjalainen, T.⁶

17
- 0038782147
- M.P. Savariau-Lacomme, C. Lebarbier, T. Karjalainen, A. Collignon, and C. Janoir J. Bacteriol. 185 2003 4461
- (2003) J. Bacteriol. , vol.185 , pp. 4461
- Savariau-Lacomme, M.P.¹ Lebarbier, C.² Karjalainen, T.³ Collignon, A.⁴ Janoir, C.⁵

18
- 0036785598
- E. Calabi, F. Calabi, A.D. Phillips, and N.F. Fairweather Infect. Immun. 70 2002 5770
- (2002) Infect. Immun. , vol.70 , pp. 5770
- Calabi, E.¹ Calabi, F.² Phillips, A.D.³ Fairweather, N.F.⁴

19
- 45249092259
- A. Wright, D. Drudy, L. Kyne, K. Brown, and N.F. Fairweather J. Med. Microbiol. 57 2008 750
- (2008) J. Med. Microbiol. , vol.57 , pp. 750
- Wright, A.¹ Drudy, D.² Kyne, L.³ Brown, K.⁴ Fairweather, N.F.⁵

20
- 20644450358
- A. Wright, R. Wait, S. Begum, B. Crossett, J. Nagy, K. Brown, and N. Fairweather Proteomics 5 2005 2443
- (2005) Proteomics , vol.5 , pp. 2443
- Wright, A.¹ Wait, R.² Begum, S.³ Crossett, B.⁴ Nagy, J.⁵ Brown, K.⁶ Fairweather, N.⁷

21
- 60649099858
- R.P. Fagan, D. Albesa-Jove, O. Qazi, D.I. Svergun, K.A. Brown, and N.F. Fairweather Mol. Microbiol. 71 2009 1308
- (2009) Mol. Microbiol. , vol.71 , pp. 1308
- Fagan, R.P.¹ Albesa-Jove, D.² Qazi, O.³ Svergun, D.I.⁴ Brown, K.A.⁵ Fairweather, N.F.⁶

22
- 0031980139
- I. Poilane, T. Karjalainen, M.C. Barc, P. Bourlioux, and A. Collignon Can. J. Microbiol. 44 1998 157
- (1998) Can. J. Microbiol. , vol.44 , pp. 157
- Poilane, I.¹ Karjalainen, T.² Barc, M.C.³ Bourlioux, P.⁴ Collignon, A.⁵

23
- 0019507583
- E.K. Steffen, and D.J. Hentges J. Clin. Microbiol. 14 1981 153
- (1981) J. Clin. Microbiol. , vol.14 , pp. 153
- Steffen, E.K.¹ Hentges, D.J.²

24
- 34548124567
- J.T. Heap, O.J. Pennington, S.T. Cartman, G.P. Carter, and N.P. Minton J. Microbiol. Methods 70 2007 452
- (2007) J. Microbiol. Methods , vol.70 , pp. 452
- Heap, J.T.¹ Pennington, O.J.² Cartman, S.T.³ Carter, G.P.⁴ Minton, N.P.⁵

25
- 67349114409
- D. Lyras, J.R. O'Connor, P.M. Howarth, S.P. Sambol, G.P. Carter, T. Phumoonna, R. Poon, V. Adams, G. Vedantam, S. Johnson, D.N. Gerding, and J.I. Rood Nature 458 2009 1176
- (2009) Nature , vol.458 , pp. 1176
- Lyras, D.¹ O'Connor, J.R.² Howarth, P.M.³ Sambol, S.P.⁴ Carter, G.P.⁵ Phumoonna, T.⁶ Poon, R.⁷ Adams, V.⁸ Vedantam, G.⁹ Johnson, S.¹⁰ Gerding, D.N.¹¹ Rood, J.I.¹²

26
- 77950645757
- A.F. Berry, W.P. Heal, A.K. Tarafder, T. Tolmachova, R.A. Baron, M.C. Seabra, and E.W. Tate ChemBioChem 11 2010 771
- (2010) ChemBioChem , vol.11 , pp. 771
- Berry, A.F.¹ Heal, W.P.² Tarafder, A.K.³ Tolmachova, T.⁴ Baron, R.A.⁵ Seabra, M.C.⁶ Tate, E.W.⁷

27
- 78650363876
- W.P. Heal, T.H. Dang, and E.W. Tate Chem. Soc. Rev. 40 2011 246
- (2011) Chem. Soc. Rev. , vol.40 , pp. 246
- Heal, W.P.¹ Dang, T.H.² Tate, E.W.³

28
- 51349154761
- W.P. Heal, S.R. Wickramasinghe, and E.W. Tate Curr. Drug Discov. Technol. 5 2008 200
- (2008) Curr. Drug Discov. Technol. , vol.5 , pp. 200
- Heal, W.P.¹ Wickramasinghe, S.R.² Tate, E.W.³

29
- 77249157733
- J.C. Thomas, J.L. Green, R.I. Howson, P. Simpson, D.K. Moss, S.R. Martin, A.A. Holder, E. Cota, and E.W. Tate Mol. Biosyst. 6 2010 494
- (2010) Mol. Biosyst. , vol.6 , pp. 494
- Thomas, J.C.¹ Green, J.L.² Howson, R.I.³ Simpson, P.⁴ Moss, D.K.⁵ Martin, S.R.⁶ Holder, A.A.⁷ Cota, E.⁸ Tate, E.W.⁹

30
- 33746467082
- P. Thongyoo, E.W. Tate, and R.J. Leatherbarrow Chem. Commun. 2006 2848
- (2006) Chem. Commun. , pp. 2848
- Thongyoo, P.¹ Tate, E.W.² Leatherbarrow, R.J.³

31
- 34547566772
- P. Thongyoo, A.M. Jaulent, E.W. Tate, and R.J. Leatherbarrow ChemBioChem 8 2007 1107
- (2007) ChemBioChem , vol.8 , pp. 1107
- Thongyoo, P.¹ Jaulent, A.M.² Tate, E.W.³ Leatherbarrow, R.J.⁴

32
- 41549150296
- P. Thongyoo, N. Roque-Rosell, R.J. Leatherbarrow, and E.W. Tate Org. Biomol. Chem. 6 2008 1462
- (2008) Org. Biomol. Chem. , vol.6 , pp. 1462
- Thongyoo, P.¹ Roque-Rosell, N.² Leatherbarrow, R.J.³ Tate, E.W.⁴

33
- 70350059832
- P. Thongyoo, C. Bonomelli, R.J. Leatherbarrow, and E.W. Tate J. Med. Chem. 52 2009 6197
- (2009) J. Med. Chem. , vol.52 , pp. 6197
- Thongyoo, P.¹ Bonomelli, C.² Leatherbarrow, R.J.³ Tate, E.W.⁴

34
- 77949799228
- T.H. Dang, L. de la Riva, R.P. Fagan, E.M. Storck, W.P. Heal, C. Janoir, N.F. Fairweather, and E.W. Tate ACS Chem. Biol. 5 2010 279
- (2010) ACS Chem. Biol. , vol.5 , pp. 279
- Dang, T.H.¹ De La Riva, L.² Fagan, R.P.³ Storck, E.M.⁴ Heal, W.P.⁵ Janoir, C.⁶ Fairweather, N.F.⁷ Tate, E.W.⁸

35
- 71749087319
- J.M. Kirby, H. Ahern, A.K. Roberts, V. Kumar, Z. Freeman, K.R. Acharya, and C.C. Shone J. Biol. Chem. 284 2009 34666
- (2009) J. Biol. Chem. , vol.284 , pp. 34666
- Kirby, J.M.¹ Ahern, H.² Roberts, A.K.³ Kumar, V.⁴ Freeman, Z.⁵ Acharya, K.R.⁶ Shone, C.C.⁷

36
- 53749083462
- P.J. Lupardus, A. Shen, M. Bogyo, and K.C. Garcia Science 322 2008 265
- (2008) Science , vol.322 , pp. 265
- Lupardus, P.J.¹ Shen, A.² Bogyo, M.³ Garcia, K.C.⁴

37
- 78649357145
- A.W. Puri, P.J. Lupardus, E. Deu, V.E. Albrow, K.C. Garcia, M. Bogyo, and A. Shen Chem. Biol. 17 2011 1201
- (2011) Chem. Biol. , vol.17 , pp. 1201
- Puri, A.W.¹ Lupardus, P.J.² Deu, E.³ Albrow, V.E.⁴ Garcia, K.C.⁵ Bogyo, M.⁶ Shen, A.⁷

38
- 67650290548
- A. Shen, P.J. Lupardus, V.E. Albrow, A. Guzzetta, J.C. Powers, K.C. Garcia, and M. Bogyo Nat. Chem. Biol. 5 2009 469
- (2009) Nat. Chem. Biol. , vol.5 , pp. 469
- Shen, A.¹ Lupardus, P.J.² Albrow, V.E.³ Guzzetta, A.⁴ Powers, J.C.⁵ Garcia, K.C.⁶ Bogyo, M.⁷

39
- 79952360670
- A. Shen, P.J. Lupardus, M.M. Gersch, A.W. Puri, V.E. Albrow, K.C. Garcia, and M. Bogyo Nat. Struct. Mol. Biol. 18 2011 364
- (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 364
- Shen, A.¹ Lupardus, P.J.² Gersch, M.M.³ Puri, A.W.⁴ Albrow, V.E.⁵ Garcia, K.C.⁶ Bogyo, M.⁷

40
- 0036302998
- E. Calabi, and N. Fairweather J. Bacteriol. 184 2002 3886
- (2002) J. Bacteriol. , vol.184 , pp. 3886
- Calabi, E.¹ Fairweather, N.²

41
- 35048837277
- C. Janoir, S. Pechine, C. Grosdidier, and A. Collignon J. Bacteriol. 189 2007 7174
- (2007) J. Bacteriol. , vol.189 , pp. 7174
- Janoir, C.¹ Pechine, S.² Grosdidier, C.³ Collignon, A.⁴

42
- 79959365481
- L. De la Riva, S. Willing, E.W. Tate, and N. Fairweather J. Bacteriol. 193 2011 3276
- (2011) J. Bacteriol. , vol.193 , pp. 3276
- De La Riva, L.¹ Willing, S.² Tate, E.W.³ Fairweather, N.⁴

43
- 84886522889
- W.P. Heal, S.R. Wickramasinghe, P.W. Bowyer, A.A. Holder, D.F. Smith, R.J. Leatherbarrow, and E.W. Tate Chem. Commun. 2008 480
- (2008) Chem. Commun. , pp. 480
- Heal, W.P.¹ Wickramasinghe, S.R.² Bowyer, P.W.³ Holder, A.A.⁴ Smith, D.F.⁵ Leatherbarrow, R.J.⁶ Tate, E.W.⁷

44
- 45449094211
- W.P. Heal, S.R. Wickramasinghe, R.J. Leatherbarrow, and E.W. Tate Org. Biomol. Chem. 6 2008 2308
- (2008) Org. Biomol. Chem. , vol.6 , pp. 2308
- Heal, W.P.¹ Wickramasinghe, S.R.² Leatherbarrow, R.J.³ Tate, E.W.⁴

45
- 76249116706
- W.P. Heal, and E.W. Tate Org. Biomol. Chem. 8 2010 731
- (2010) Org. Biomol. Chem. , vol.8 , pp. 731
- Heal, W.P.¹ Tate, E.W.²

46
- 79955036748
- W.P. Heal, B. Jovanovic, S. Bessin, M.H. Wright, A.I. Magee, and E.W. Tate Chem. Commun. 47 2011 4081
- (2011) Chem. Commun. , vol.47 , pp. 4081
- Heal, W.P.¹ Jovanovic, B.² Bessin, S.³ Wright, M.H.⁴ Magee, A.I.⁵ Tate, E.W.⁶

47
- 33745550745
- M. Sebaihia, B.W. Wren, P. Mullany, N.F. Fairweather, N. Minton, R. Stabler, N.R. Thomson, A.P. Roberts, A.M. Cerdeno-Tarraga, H. Wang, M.T. Holden, A. Wright, C. Churcher, M.A. Quail, S. Baker, N. Bason, K. Brooks, T. Chillingworth, A. Cronin, P. Davis, L. Dowd, A. Fraser, T. Feltwell, Z. Hance, S. Holroyd, K. Jagels, S. Moule, K. Mungall, C. Price, E. Rabbinowitsch, S. Sharp, M. Simmonds, K. Stevens, L. Unwin, S. Whithead, B. Dupuy, G. Dougan, B. Barrell, and J. Parkhill Nat. Genet. 38 2006 779
- (2006) Nat. Genet. , vol.38 , pp. 779
- Sebaihia, M.¹ Wren, B.W.² Mullany, P.³ Fairweather, N.F.⁴ Minton, N.⁵ Stabler, R.⁶ Thomson, N.R.⁷ Roberts, A.P.⁸ Cerdeno-Tarraga, A.M.⁹ Wang, H.¹⁰ Holden, M.T.¹¹ Wright, A.¹² Churcher, C.¹³ Quail, M.A.¹⁴ Baker, S.¹⁵ Bason, N.¹⁶ Brooks, K.¹⁷ Chillingworth, T.¹⁸ Cronin, A.¹⁹ Davis, P.²⁰ more..

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.