Cyclosporine up-regulates Krüppel-like factor-4 (KLF4) in vascular smooth muscle cells and drives phenotypic modulation in vivo

Journal of Pharmacology and Experimental Therapeutics

Volumn 333, Issue 1, 2010, Pages 34-42

  Garvey, Sean M ^a   Sinden, Daniel S ^a   Schoppee Bortz, Pamela D ^a   Wamhoff, Brian R ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 8; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLOSPORIN; GELATINASE B; KRUPPEL LIKE FACTOR 4; MESSENGER RNA; MYOCARDIN; MYOSIN; SMOOTHELIN; STROMELYSIN; TRANSGELIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAROTID ARTERY; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; GENE EXPRESSION; IMMUNOFLUORESCENCE; IN VIVO STUDY; MICROSCOPY; MONOCULTURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE; UPREGULATION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; ANTIGENS, DIFFERENTIATION; AORTA; CAROTID ARTERIES; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLOSPORINE; DOWN-REGULATION; IMMUNOSUPPRESSIVE AGENTS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MYOCYTES, SMOOTH MUSCLE; RATS; RATS, SPRAGUE-DAWLEY; TUNICA MEDIA; UP-REGULATION;

EID: 77949740434     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.163949     Document Type: Article

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