Cyclosporin A increases expression of matrix metalloproteinase 9 and 2 and invasiveness in vitro of the first-trimester human trophoblast cells via the mitogen-activated protein kinase pathway

Human Reproduction

Volumn 22, Issue 10, 2007, Pages 2743-2750

  Zhou, Wen Hui ^a,b   Du, Mei Rong ^a   Dong, Lin ^a   Zhu, Xiao Yong ^a   Yang, Jin Ying ^a   He, Ying Yan ^a   Li, Da Jin ^a,c  

^a FUDAN UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

^c HAINAN MEDICAL UNIVERSITY   (China)

Author keywords

Cyclosporin A; Invasiveness; MAPK; Matrix metalloproteinase; Trophoblast cell

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYCLOSPORIN A; GELATINASE A; GELATINASE B; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL TISSUE; ARTICLE; CELL INVASION; CELL ISOLATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL CULTURE; IN VITRO STUDY; NONHUMAN; PLACENTA; PREGNANCY COMPLICATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TROPHOBLAST; ZYMOGRAPHY;

EID: 34548063101     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dem097     Document Type: Article

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