메뉴 건너뛰기




Volumn 56, Issue 6, 1999, Pages 2147-2159

Expression of apoptosis regulatory genes in chronic cyclosporine nephrotoxicity favors apoptosis

Author keywords

Death genes; Fibrosis; Immunosuppression; Nephrotoxicity; Programmed cell death

Indexed keywords

CASPASE 3; CYCLOSPORIN; FAS ANTIGEN; PROTEIN BCL 2; PROTEIN P53;

EID: 0033405266     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.00794.x     Document Type: Article
Times cited : (123)

References (60)
  • 1
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • 1. Nagata S: Apoptosis by death factor. Cell 88:355-365, 1997
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 2
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • 2. Schwartzman RA, Cidlowski JA: Apoptosis: The biochemistry and molecular biology of programmed cell death. Endocr Rev 14:133-151, 1993
    • (1993) Endocr Rev , vol.14 , pp. 133-151
    • Schwartzman, R.A.1    Cidlowski, J.A.2
  • 4
    • 0028473454 scopus 로고
    • Apoptosis and the kidney
    • 4. Savill J: Apoptosis and the kidney. J Am Soc Nephrol 5:12-21, 1994
    • (1994) J Am Soc Nephrol , vol.5 , pp. 12-21
    • Savill, J.1
  • 7
    • 0025880971 scopus 로고
    • Drug-target interactions: Only the first step in the commitment to a programmed cell death?
    • 7. Dive C, Hickman JA: Drug-target interactions: Only the first step in the commitment to a programmed cell death? Br J Cancer 64:192-196, 1991
    • (1991) Br J Cancer , vol.64 , pp. 192-196
    • Dive, C.1    Hickman, J.A.2
  • 8
    • 0025732732 scopus 로고
    • Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli
    • 8. Lennon SV, Martin SJ, Cotte TG: Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli. Cell Prolif 24:203-214, 1991
    • (1991) Cell Prolif , vol.24 , pp. 203-214
    • Lennon, S.V.1    Martin, S.J.2    Cotte, T.G.3
  • 9
    • 0023897646 scopus 로고
    • Cell death in the diseased glomerulus
    • 9. Harris DJ: Cell death in the diseased glomerulus. Histopathology 12:679-683, 1988
    • (1988) Histopathology , vol.12 , pp. 679-683
    • Harris, D.J.1
  • 10
    • 0028116649 scopus 로고
    • Mesangial cell apoptosis: The major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis
    • 10. Baker AJ, Mooney A, Hughes J, Lombardi D, Johnson RJ, Savill J: Mesangial cell apoptosis: The major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis. J Clin Invest 94:2105-2116, 1994
    • (1994) J Clin Invest , vol.94 , pp. 2105-2116
    • Baker, A.J.1    Mooney, A.2    Hughes, J.3    Lombardi, D.4    Johnson, R.J.5    Savill, J.6
  • 12
    • 0030053799 scopus 로고    scopus 로고
    • Role of apoptosis in growth and differentiation of proximal tubule cells in primary cultures
    • 12. Tang MJ, Cheng YR, Lin HH: Role of apoptosis in growth and differentiation of proximal tubule cells in primary cultures. Biochem Biophys Res Commun 218:658-664, 1996
    • (1996) Biochem Biophys Res Commun , vol.218 , pp. 658-664
    • Tang, M.J.1    Cheng, Y.R.2    Lin, H.H.3
  • 13
  • 14
    • 0029821680 scopus 로고    scopus 로고
    • Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury
    • 14. Lieberthal W, Levine JS: Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury. Am J Physiol 271:F477-F488, 1996
    • (1996) Am J Physiol , vol.271
    • Lieberthal, W.1    Levine, J.S.2
  • 15
    • 0029881461 scopus 로고    scopus 로고
    • Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: Apoptosis vs. necrosis
    • 15. Lieberthal W, Triaca V, Levine J: Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: Apoptosis vs. necrosis. Am J Physiol 270:F700-F708, 1996
    • (1996) Am J Physiol , vol.270
    • Lieberthal, W.1    Triaca, V.2    Levine, J.3
  • 16
    • 0025695607 scopus 로고
    • Cellular events in experimental unilateral ischemic renal atrophy and in regeneration after contralateral nephrectomy
    • 16. Gobé GC, Axelsen RA, Searle JW: Cellular events in experimental unilateral ischemic renal atrophy and in regeneration after contralateral nephrectomy. Lab Invest 63:770-779, 1990
    • (1990) Lab Invest , vol.63 , pp. 770-779
    • Gobé, G.C.1    Axelsen, R.A.2    Searle, J.W.3
  • 18
    • 0023195534 scopus 로고
    • Genesis of renal tubular atrophy in experimental hydronephrosis in the rat: Role of apoptosis
    • 18. Gobé GC, Axelsen RA: Genesis of renal tubular atrophy in experimental hydronephrosis in the rat: Role of apoptosis. Lab Invest 56:273-281, 1987
    • (1987) Lab Invest , vol.56 , pp. 273-281
    • Gobé, G.C.1    Axelsen, R.A.2
  • 19
    • 0029035757 scopus 로고
    • Apoptosis and loss of renal tissue in polycystic kidney diseases
    • 19. Woo D: Apoptosis and loss of renal tissue in polycystic kidney diseases. N Engl J Med 333:18-25, 1995
    • (1995) N Engl J Med , vol.333 , pp. 18-25
    • Woo, D.1
  • 20
    • 0024976004 scopus 로고
    • Cyclosporine
    • 20. Kahan BD: Cyclosporine. N Engl J Med 321:1725-1738, 1989
    • (1989) N Engl J Med , vol.321 , pp. 1725-1738
    • Kahan, B.D.1
  • 21
    • 0029806297 scopus 로고    scopus 로고
    • Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy
    • 21. Bennett WM, Demattos A, Meyer MM, Andoh T, Barry J: Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy. Kidney Int 50:1089-1100, 1996
    • (1996) Kidney Int , vol.50 , pp. 1089-1100
    • Bennett, W.M.1    Demattos, A.2    Meyer, M.M.3    Andoh, T.4    Barry, J.5
  • 22
    • 0029857451 scopus 로고    scopus 로고
    • Cyclosporine nephropathy: Pathophysiology and clinical impact
    • 22. Shihab FS: Cyclosporine nephropathy: Pathophysiology and clinical impact. Semin Nephrol 16:536-547, 1996
    • (1996) Semin Nephrol , vol.16 , pp. 536-547
    • Shihab, F.S.1
  • 24
    • 0031012546 scopus 로고    scopus 로고
    • Nephrotoxicity of immunosuppressive drugs: Experimental and clinical observations
    • 24. Andoh TF, Burdmann EA, Bennett WM: Nephrotoxicity of immunosuppressive drugs: Experimental and clinical observations. Semin Nephrol 17:34-45, 1997
    • (1997) Semin Nephrol , vol.17 , pp. 34-45
    • Andoh, T.F.1    Burdmann, E.A.2    Bennett, W.M.3
  • 26
    • 0030745637 scopus 로고    scopus 로고
    • Salt-depletion enhances TGF-β1 and matrix proteins expression in rat chronic cyclosporine nephropathy
    • 26. Shihab FS, Andoh TF, Tanner AM, Bennett WM: Salt-depletion enhances TGF-β1 and matrix proteins expression in rat chronic cyclosporine nephropathy. Am J Kidney Dis 30:71-81, 1997
    • (1997) Am J Kidney Dis , vol.30 , pp. 71-81
    • Shihab, F.S.1    Andoh, T.F.2    Tanner, A.M.3    Bennett, W.M.4
  • 27
    • 0030801946 scopus 로고    scopus 로고
    • Angiotensin II blockade decreases TGF-β1 and matrix proteins in cyclosporine nephropathy
    • 27. Shihab FS, Bennett WM, Tanner AM, Andoh TF: Angiotensin II blockade decreases TGF-β1 and matrix proteins in cyclosporine nephropathy. Kidney Int 52:660-673, 1997
    • (1997) Kidney Int , vol.52 , pp. 660-673
    • Shihab, F.S.1    Bennett, W.M.2    Tanner, A.M.3    Andoh, T.F.4
  • 29
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • 29. Evan G, Littlewood T: A matter of life and cell death. Science 281:1317-1322, 1998
    • (1998) Science , vol.281 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 30
    • 0027298576 scopus 로고
    • Induction of cellular p53 activity by DNA damaging agents and growth arrest
    • 30. Zhan Q, Carrier F, Fornace AJ: Induction of cellular p53 activity by DNA damaging agents and growth arrest. Mol Cell Biol 13:4242-4250, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 4242-4250
    • Zhan, Q.1    Carrier, F.2    Fornace, A.J.3
  • 31
    • 0027319521 scopus 로고
    • p53 is required for radiation induced apoptosis in mouse thymocytes
    • 31. Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T: p53 is required for radiation induced apoptosis in mouse thymocytes. Nature 362:847-849, 1993
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 32
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • 32. Miyashita T, Reed JC: Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299, 1995
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 33
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • 33. Adams JM, Cory S: The Bcl-2 protein family: Arbiters of cell survival. Science 281:1322-1326, 1998
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 34
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog Bax that accelerates programmed cell death
    • 34. Oltvai ZN, Milliman CL, Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog Bax that accelerates programmed cell death. Cell 74:609-619, 1993
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 35
    • 0027944228 scopus 로고
    • Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis
    • 35. Zhan Q, Fan S, Bae I, Guellouf C, Liebermann DA, O'Connor PM, Fornace AJ: Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene 9:3743-3751, 1994
    • (1994) Oncogene , vol.9 , pp. 3743-3751
    • Zhan, Q.1    Fan, S.2    Bae, I.3    Guellouf, C.4    Liebermann, D.A.5    O'Connor, P.M.6    Fornace, A.J.7
  • 36
    • 0028927607 scopus 로고
    • The Fas death factor
    • 36. Nagata S, Golstein P: The Fas death factor. Science 267:1449-1456, 1995
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 37
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • 37. Thornberry N, Lazebnik Y: Caspases: Enemies within. Science 281:1312-1316, 1998
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.1    Lazebnik, Y.2
  • 38
    • 0028841040 scopus 로고
    • Apoptosis in the human allografted kidney: Analysis by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling
    • 38. Ito H, Kasaki N, Shomori K, Osaki M, Adachi H: Apoptosis in the human allografted kidney: Analysis by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling. Transplantation 60:794-798, 1995
    • (1995) Transplantation , vol.60 , pp. 794-798
    • Ito, H.1    Kasaki, N.2    Shomori, K.3    Osaki, M.4    Adachi, H.5
  • 39
    • 0029127639 scopus 로고
    • Transforming growth factor-β and extracellular proteins expression in acute and chronic rejection of human renal allografts
    • 39. Shihab FS, Yamamoto T, Nast CC, Cohen AH, Gold LI, Noble NA, Border WA: Transforming growth factor-β and extracellular proteins expression in acute and chronic rejection of human renal allografts. J Am Soc Nephrol 6:286-294, 1995
    • (1995) J Am Soc Nephrol , vol.6 , pp. 286-294
    • Shihab, F.S.1    Yamamoto, T.2    Nast, C.C.3    Cohen, A.H.4    Gold, L.I.5    Noble, N.A.6    Border, W.A.7
  • 41
    • 0030377608 scopus 로고    scopus 로고
    • Growth factors and apoptosis in neonatal ureteral obstruction
    • 41. Chevalier RL: Growth factors and apoptosis in neonatal ureteral obstruction. J Am Soc Nephrol 7:1098-1105, 1996
    • (1996) J Am Soc Nephrol , vol.7 , pp. 1098-1105
    • Chevalier, R.L.1
  • 45
    • 0029887283 scopus 로고    scopus 로고
    • The effect of ACE inhibitors on the expression of matrix genes and the role of p53 and p21 (WAF1) in experimental renal fibrosis
    • 45. Morrissey JJ, Ishidoya S, McCracken R, Klahr S: The effect of ACE inhibitors on the expression of matrix genes and the role of p53 and p21 (WAF1) in experimental renal fibrosis. Kidney Int 54(Suppl):S83-S87, 1996
    • (1996) Kidney Int , vol.54 , Issue.SUPPL.
    • Morrissey, J.J.1    Ishidoya, S.2    McCracken, R.3    Klahr, S.4
  • 46
    • 0030789576 scopus 로고    scopus 로고
    • Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis
    • 46. Sandau K, Pfeilschifter J, Brüne B: Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis. Kidney Int 52:378-386, 1997
    • (1997) Kidney Int , vol.52 , pp. 378-386
    • Sandau, K.1    Pfeilschifter, J.2    Brüne, B.3
  • 47
    • 0031062401 scopus 로고    scopus 로고
    • Expression of apoptosis-regulatory genes in renal proximal tubular epithelial cells exposed to high ambient glucose and in diabetic kidneys
    • 47. Ortiz A, Ziyadeh FN, Neilson EG: Expression of apoptosis-regulatory genes in renal proximal tubular epithelial cells exposed to high ambient glucose and in diabetic kidneys. J Invest Med 45:50-56, 1997
    • (1997) J Invest Med , vol.45 , pp. 50-56
    • Ortiz, A.1    Ziyadeh, F.N.2    Neilson, E.G.3
  • 49
    • 0000789698 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • 49. Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:384-387, 1992
    • (1992) Nature , vol.348 , pp. 384-387
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 50
    • 0031752760 scopus 로고    scopus 로고
    • Apoptosis and necrosis: Mechanisms of cell death induced by cyclosporine A in renal proximal tubular cell line
    • 50. Healy E, Dempsey M, Lally C, Ryan MP: Apoptosis and necrosis: Mechanisms of cell death induced by cyclosporine A in renal proximal tubular cell line. Kidney Int 54:1955-1966, 1998
    • (1998) Kidney Int , vol.54 , pp. 1955-1966
    • Healy, E.1    Dempsey, M.2    Lally, C.3    Ryan, M.P.4
  • 53
    • 0029874715 scopus 로고    scopus 로고
    • The inhibition of T-cell-receptor-induced Fas ligand upregulation by cyclosporine and FK 506
    • 53. Nakajima H, Oka T: The inhibition of T-cell-receptor-induced Fas ligand upregulation by cyclosporine and FK 506. Transplant Proc 28:1052-1055, 1996
    • (1996) Transplant Proc , vol.28 , pp. 1052-1055
    • Nakajima, H.1    Oka, T.2
  • 54
    • 0030018311 scopus 로고    scopus 로고
    • Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporine A and FK506
    • 54. Brunner T, Yoo NJ, Laface D, Ware CF, Green DR: Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporine A and FK506. Int Immunol 8:1017-1026, 1996
    • (1996) Int Immunol , vol.8 , pp. 1017-1026
    • Brunner, T.1    Yoo, N.J.2    Laface, D.3    Ware, C.F.4    Green, D.R.5
  • 56
    • 0031773717 scopus 로고    scopus 로고
    • Cyclosporine A induces apoptosis in murine tubular epithelial cells: Role of caspases
    • 56. Ortiz A, Lorz C, Catalán M, Ortiz A, Coca S, Egido J: Cyclosporine A induces apoptosis in murine tubular epithelial cells: Role of caspases. Kidney Int 68(Suppl):S25-S29, 1998
    • (1998) Kidney Int , vol.68 , Issue.SUPPL.
    • Ortiz, A.1    Lorz, C.2    Catalán, M.3    Ortiz, A.4    Coca, S.5    Egido, J.6
  • 59
    • 0001739436 scopus 로고    scopus 로고
    • Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell
    • 59. Leri A, Claudio PP, Li Q, Wang X, Reiss K, Wang S, Malhotra A: Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest 101:1326-1342, 1998
    • (1998) J Clin Invest , vol.101 , pp. 1326-1342
    • Leri, A.1    Claudio, P.P.2    Li, Q.3    Wang, X.4    Reiss, K.5    Wang, S.6    Malhotra, A.7
  • 60
    • 0031569094 scopus 로고    scopus 로고
    • 2+ elevation and cyclosporine A synergistically induce TGF-β1-mediated apoptosis in lymphocytes
    • 2+ elevation and cyclosporine A synergistically induce TGF-β1-mediated apoptosis in lymphocytes. J Immunol 158:2527-2534, 1997
    • (1997) J Immunol , vol.158 , pp. 2527-2534
    • Andjelic, S.1    Khanna, A.2    Suthanthiran, M.3    Nikolic-Zugic, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.