Distribution and excretion of radiolabeled temoporfin in a murine tumor model

Photochemistry and Photobiology

Volumn 63, Issue 6, 1996, Pages 885-891

  Whelpton, Robin ^a   Michael Titus, Adina T ^a   Jamdar, Ravi P ^a   Abdillahi, Kaltun ^a   Grahn, Michael F ^b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE;

CARBON; MESOPORPHYRIN; PHOTOSENSITIZING AGENT; TEMOPORFIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; COLORECTAL TUMOR; FEMALE; HALF LIFE TIME; METABOLISM; MOUSE; TISSUE DISTRIBUTION;

ANIMALS; CARBON RADIOISOTOPES; COLORECTAL NEOPLASMS; FEMALE; HALF-LIFE; MESOPORPHYRINS; MICE; MICE, INBRED BALB C; PHOTOSENSITIZING AGENTS; TISSUE DISTRIBUTION;

EID: 0030155969     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1996.tb09646.x     Document Type: Article

References (22)

1. Dougherty, T. J., W. R. Potter and D. Bellnier (1990) Photodynamic therapy for the treatment of cancer: current status and advances. In Photodynamic Therapy of Neoplastic Disease, Vol. I (Edited by D. Kessel), pp. 1-19. CRC Press, Boca Raton, FL.
2. Gomer, C. J. (1991) Preclinical examination of first and second generation photosensitizers used in pholodynamic therapy. Photochem, Photobiol. 54, 1093-1107.
3. Bonnett, R., R. D. White, U.-J. Winfield and M. C. Berenbaum (1989) Hydroporphyrins of the meso-tetra(hydroxyphenyl)-porphyrin series as tumour photosensitizers. Biochem. J. 261, 277-280.
4. Ris, H.-B., H. J. Altermatt, R. Inderbitzi, R. Hess, B. Nachbur, J. C. M. Stewart, Q. Wang, C. K. Lim, R. Bonnett, M. C. Berenbaum and U. Althaus (1991) Photodynamic therapy with chlorins for diffuse malignant mesothelioma: initial clinical results. Br. J. Cancer 64, 1116-1120
5. Berenbaum, M C., S. L. Akande, R. Bonnett, H. Kaur, S. Ioannou, R. D. White and U.-J. Winfield (1986) Meso-tetra(hydroxyphenyl)porphyrins, a new class of potent tumour photosensitizers with favourable selectivity. Br. J. Cancer 54, 717-725.
6. Berenbaum, M. C., R. Bonnett, E. B. Chevretton, S L. Akande-Adebakin and M. Ruston (1993) Selectivity of meso-tetra(hydroxyphenyl)porphyrins and chlorins and of Photofrin II in causing photodamage in tumor, skin, muscle and bladder. The concept of cost-benefit in analyzing the results. Lasers Med. Sci. 8, 235-243.
7. Ris, H.-B., H. J. Altermatt, B. Nachbur, J. C. M. Stewart, Q. Wang, C. K. Lim, R. Bonnett and U. Althaus (1993) Effect of drug-light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma. Int. J. Cancer 53, 141-146.
8. Ma, L. W., J. Moan and K. Berg (1994) Evaluation of a new photosensitizer, meso-tetra-hydroxyphenyl-chlorin, for use in photodynamic therapy: a comparison of its photobiological properties with those of two other photosensitizers. Int. J. Cancer 57, 883-888.
9. Lofgren, L. A., A. M. Ronn, A L. Abramson, M. J. Shikowitz, M. Nouri, C. J. Lee, J. Batti and B. M. Steinberg (1994) Photodynamic therapy using in-tetra(hydroxyphenyl) chlorin. An animal model. Arch. Otolaryngol. Head & Neck Surg. 120, 1355-1362.
10. Whelpton, R., A. T. Michael-Titus, S. S. Basra and M. Grahn (1995) Distribution of temoporfin, a new photosensitizer for the photodynamic therapy of cancer, in a murine tumor model Photochem. Photobiol. 61, 397-401.
11. Whelpton, R. (1988) Micro-computer pharmacokinetic curve fitting using the method of residuals with on screen line drawing. Br. J. Pharmacol. 95, 907P.
12. Nielsen-Kudsk, F. (1985) A microcomputer program in BASIC for the iterative, non-linear data-fitting to pharmacokinetic functions. Int. J. Biomed. Comput. 14, 95-107.
13. Gibaldi, M. and D. Perrier (1975) Pharmacokinetics. In Drugs and the Pharmaceutical Sciences, Vol. 1 (Edited by J. Swarbrick), pp. 62-65. Marcel Dekker, New York.
14. Kessel, D., K. Woodburn, D. Decker and E. Sykes (1995) Fractionation of Cremophor EL delineates components responsible for plasma lipoprotein alterations and multidrug resistance reversal. Oncol. Res. 7, 207-212.
15. Michael-Titus, A. T., R. Whelpton and Z. Yaqub (1995) Binding of temoporfin to the lipoprotein fractions of human serum. Br. J. Clin. Pharmacol. 40, 594-597.
16. De Smidt, P. C., A. J. Versluis and Th. J C. Van Berkel (1992) Transport of sulfonated tetraphenylporphine by lipoproteins in the hamster. Biochem. Pharmacol. 43, 2567-2573.
17. Wang, Q., H. J. Altermatt, H.-B. Ris, B. E. Reynolds, J. C. M. Stewart, R. Bonnett and C. K. Lim (1993) Determination of 5,10,15,20-tetra-(in-hydroxyphenyl)chlorin in tissues by high performance liquid chromatography. Biomed Chromatogr. 7, 155-157.
18. Jones, R. M., Q. Wang, J. H. Lamb, B. D. Djelal, R. Bonnett and C. K. Lim (1996) Identification of photochemical oxidation products of 5,10,15.20-tetra(m-hydroxyphenyl)chlorin by on-line high-performance liquid chromatography - electrospray ionization tandem mass spectrometry J. Chromatogr. A. 772, 257-265.
19. Ansell, J. K., M. L. De Jode, M. F. Grahn, J. Maudsley and N. S Williams (1995) Correlation of photodynamic effect with surface fluorescence and drug assay. Lasers Surg. Med. 7, 41.
20. Ferrario, A., D. Kessel and C. J. Gomer (1992) Metabolic properties and photosensitizing responsiveness of mono-L-aspartyl chlorine in a mouse-tumor model. Cancer Res. 52, 2890-2893.
21. Dougherty, T. J (1993) Photodynamic therapy. Photochem. Photobiol. 58, 895-900.
22. Bellnier, D. A , Y.-K. Ho, R. K. Pandey, J. R. Missen and T. J. Dougherty (1989) Distribution and elimination of photofrin II in mice. Photochem. Photobiol. 50 221-228.