Pharmacokinetics of Tetra(m-hydroxyphenyl)chlorin in Human Plasma and Individualized Light Dosimetry in Photodynamic Therapy

Photochemistry and Photobiology

Volumn 67, Issue 5, 1998, Pages 596-602

  Glanzmann, Thomas ^a   Hadjur, Christophe ^a   Zellweger, Matthieu ^a   Grosjean, Pierre ^b   Forrer, Martin ^a   Ballini, Jean Pierre ^a   Monnier, Philippe ^b   Van Den Bergh, Hubert ^a   Lim, Chang Kee ^c   Wagnières, Georges ^a  

^a EPFL   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MESOPORPHYRIN; RADIOSENSITIZING AGENT; TEMOPORFIN;

ARTICLE; BLOOD; CLINICAL TRIAL; FEMALE; HUMAN; MALE; PHOTOCHEMOTHERAPY; RADIATION RESPONSE; SPECTROFLUOROMETRY;

DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; MALE; MESOPORPHYRINS; PHOTOCHEMOTHERAPY; RADIATION-SENSITIZING AGENTS; SPECTROMETRY, FLUORESCENCE;

EID: 0032058984     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1998.tb09099.x     Document Type: Article

References (35)

1. van den Bergh, H. (1997) Photochemotherapy: PDT and other modalities. In Photochemotherapy: Photodynamic Therapy and Other Modalities III: Vol. 3191 (Edited by B. E. K. Berg, Z. Malik and J. Moan), pp. 2-20. Proc. SPIE.
2. Stables, G. I. and D. V. Ash (1995) Photodynamic therapy. Cancer Treatment Rev. 21, 311-323.
3. Schuitmaker, J. J., P. Baas, H. L. L. M. v. Leengoed, F. W. v. d. Muelen, W. Star and N. v. Zandwijk (1996) Photodynamic therapy: a promising new modality for the treatment of cancer. J. Photochem. Photobiol. B: Biol. 34, 3-12.
4. Monnier, P., M. Savary, C. Fontolliet, G. Wagnières, A. Châtelain, P. Cornaz, C. Depeursinge and H. van den Bergh (1990) Photodetection and photodynamic therapy of 'early' squamous cell carcinomas of the pharynx, oesophagus and tracheo-bronchial tree. Lasers Med. Sci. 5, 149-169.
5. Grosjean, P., J.-F. Savary, G. Wagnières, J. Mizeret, A. Woodtli, J.-F. Theumann, C. Fontolliet, H. van den Bergh and P. Monnier (1996) Tetra(m-hydroxyphenyl)chlorin clinical photodynamic therapy of early bronchial and oesophageal cancers. Lasers Med. Sci. 11, 227-235.
6. Grosjean, P., J.-F. Savary, J. Mizeret, G. Wagnières, A. Woodtli, J.-F. Theumann, C. Fontolliet, H. van den Bergh and P. Monnier (1996) Photodynamic therapy for cancer of the upper aerodigestive tract using tetra (m-hydroxphenyl)chlorin. J. Clin Laser Med. Surg. 14/5, 281-287.
7. Savary, J. F., P. Monnier, C. Fontolliet, J. Mizeret, G. Wagnières, D. Braichotte and H. van den Bergh (1997) Photodynamic therapy for early squamous-cell carcinomas of the esophagus, bronchi, and mouth with m-tetra(hydroxyphenyl) chlorin. Arch. Otolaryngol. Head Neck Surg. 123, 162-168.
8. Ris, H. B., H. J. Altermatt, B. Nachbur, C. M. Stewart, Q. Wang, C. K. Lim, R. Bonnett and U. Althaus (1996) Intraoperative photodynamic therapy with m-tetrahydroxyphenylchlorin for chest malignancies. Lasers Surg. Med. 18, 39-45.
9. Bonnett, R., R. D. White, U.-J. Winfield and M. C. Berenbaum (1989) Hydroporphyrins of the meso-tetra(hydroxyphenyl)porphyrin series as tumor photosentisizers. Biochem. J. 261, 277-280.
10. Wagnières, G., C. Hadjur, P. Grosjean, D. Braichotte, J.-F. Savary, P. Monnier and H. van den Bergh (1998) Clinical evaluation of the cutaneous phototoxicity of a second generation photosensitizer for PDT: mTHPC. Photochem. Photobiol. (In press)
11. Braichotte, D., J. F. Savary, T. Glanzmann, P. Westermann, S. Folli, G. Wagnières, P. Monnier and H. van den Bergh (1995) Clinical pharmacokinetic studies of tetra(meta-hydroxyphenol)chlorin in squamous-cell carcinoma by fluorescence spectroscopy at 2 wavelengths. Int. J. Cancer 63, 198-204.
12. McLeod, H. L. and W. E. Evans (1995) Clinical pharmacokinetics of anticancer drugs. In Handbook of Pharmacokinetic/ Pharmacodynamic Correlation (Edited by H. Derendorf and G. Hochhaus), pp. 389-414. CRC Press, Boca Raton, FL.
13. Braichotte, D., J.-F. Savary, T. Glanzmann, P. Monnier, G. Wagnières and H. van den Bergh (1996) Optimizing light dosimetry in photodynamic therapy of the bronchi by fluorescence spectroscopy. Lasers Med. Sci. 11, 247-254.
14. Braichotte, D. R., J. F. Savary, P. Monnier and H. E. van den Bergh (1996) Optimizing light dosimetry in photodynamic therapy of early-stage carcinomas of the esophagus using fluorescence spectroscopy. Lasers Surg. Med. 19, 340-346.
15. Miller, J. N. (1992) VI: the method of standard additions. Spectrosc. Europe 4, 26-27.
16. Sun, Y., L. W. Oberley and Y. Li (1988) A simple method for clinical assay of superoxide dismutase. Clin. Chem. 43, 497-500.
17. Glanzmann, T., J.-P. Ballini, P. Jichlinski, P. Grosjean, H. van den Bergh and G. Wagnières (1996) Tissue characterization by time-resolved fluorescence spectroscopy of endogenous and exogenous fluorochromes: apparatus design and preliminary in vivo and ex vivo results. In Optical Biopsies and Microscopic Techniques, Vol. 2926 (Edited by I. Bigio), pp 41-50. Proc. SPIE.
18. Wagnières, G., C. Hadjur, A. Woodtli, J. Mizeret, P. Grosjean, D. Braichotte, M. Forrer, J.-F. Theumann, P. Monnier and H. van den Bergh (1998) Clinical evaluation of the phototoxic effects on cancers and normal tissues in PDT with mTHPC. Submitted to Photochem. Photobiol.
19. Taylor, J. R. (1982) An Introduction to Error Analysis, Chapter 9. University Science Books, Mill Valley.
20. Westermann, P., T. Glanzmann, S. Andrejevic, D. Braichotte, J.-P. Mach, M. Forrer, G. Wagnières, H. van den Bergh and S. Folli (1998) Longer circulating half-life and higher tumor selectivity on m-THPC conjugated to polyethylene glycol, as compared to the free form of this photosensitizer. Int. J. Cancer. (In press)
21. Barberi, M., H. Rezzoug, J. L. Merlin and F. Guillemin (1997) Sensitive isocratic liquid chromatographic assay for the determination of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin in plasma and tissue with electrochemical detection. J. Chromatogr. B 688, 331-338.
22. Lofgren, L. A., A. M. Ronn, A. L. Abramson, M. J. Shikowitz, M. Nouri, C. J. Lee, J. Batti and B. M. Steinberg (1994) Photodynamic therapy using m-tetra(hydroxylphenyl) chlorin. Arch. Otolaryngol. Head Neck Surg. 120, 1355-1362.
23. Whelpton, R., A. T. Michael-Titus, S. S. Basra and M. Grahn (1995) Distribution of temoporfin, a new photosensitizer for the photodynamic therapy of cancer, in a murine tumor-model. Photochem. Photobiol. 61(4), 397-401.
24. Ma, L., J. Moan and K. Berg (1994) Evlauation of a new photosensitizer, meso-tetra-hydroxyphenyl-chlorin, for use in photodynamic therapy: a comparison of its photobiological properties with those of two other photosensitizers. Int. J. Cancer 57, 883-888.
25. Egger, N. G., M. Montamedi, M. Powsang, E. Orihuela and K. E. Anderson (1996) Accumulation of porphyrins in plasma and tissues of dogs after delta-aminolevulinic-acid administration -implications for photodynamic therapy. Pharmacology 52, 362-370.
26. Glanzmann, T. (1996) Fluorescence studies of mTHPC and their application in PDT. The Rank Prize Funds, Mini-Symposium on Photodynamic Therapy.
27. Ronn, A. M., M. Nouri, L. A. Lofgren, B. M. Steinberg, A. Westerborn, T. Windahl, M. J. Shikowitz and A. L. Abramson (1996) Human tissue-levels and plasma pharmacokinetics of temoporfin (Foscan(R), Mthpc). Lasers Med. Sci. 11, 267-272.
28. Lee, P. I. D. and G. L. Amidon (1996) Drug distribution into tissue - tissue penetration. In Pharmacokinetic Analysis, pp. 213-236. Technomic Publishing, Lancaster.
29. Boyle, R. W. and D. Dolphin (1996) Structure and biodistribution relationships of photodynamic sensitizers. Photochem. Photobiol. 64(3), 469-485.
30. Mazière, J. C., P. Molière and R. Santus (1991) The role of the low density lipoprotein receptor pathway in the delivery of lipophilic photosensitizers in the photodynamic therapy of tumours. J. Photochem. Photobiol. B: Biol. 8, 351-360.
31. Reddi, E. (1997) Role of delivery vehicles for photosensitizers in the photodynamic therapy of tumours. J. Photochem. Photobiol. B: Biol. 37, 189-195.
32. Whelpton, R., A. T. Michael-Titus, R. P. Jamdar, K. Abdillahi and M. F. Grahn (1996) Distribution and excretion of radiolabeled temoporfin in a murine tumor model. Photochem. Photobiol. 63(6), 885-891.
33. Ronn, A. M., J. Batti, C. J. Lee, D. Yoo, M. E. Siegel, M. Nouri, L. A. Lofgren and b. M. Steinberg (1997) Comparative biodistribution of meta-tetra(hydroxyphenyl) chlorin in multiple-species - clinical implications for photodynamic therapy. Lasers Surg. Med. 20, 437-442.
34. Wang, Q., H. Altermatt, H.-B. Ris, B. Reynolds, J. Stewart, R. Bonnett and C. K. Lim (1993) Determination of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin in tissues by high performance liquid chromatography. Biomed. Chromatogr. 7, 155-157.
35. Menezes da Silva, F. A. and E. L. Newman (1995) Time-dependent photodynamic damage to blood vessels: correlation with serum photosensitizer levels. Photochem. Photobiol. 61(4), 414-416.