Efficient skin permeation of soluble proteins via flexible and functional nano-carrier

Journal of Controlled Release

Volumn 157, Issue 2, 2012, Pages 272-278

  Choi, Won Il ^a   Lee, Jong Hyun ^a   Kim, Ja Young ^a   Kim, Jin Chul ^b   Kim, Young Ha ^a   Tae, Giyoong ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Kangwon National University   (South Korea)

Author keywords

Chitosan; Nano carrier; Pluronic; Proteins; Transdermal

Indexed keywords

BIOMACROMOLECULES; DELIVERY VEHICLE; GALACTOSIDASES; HUMAN CADAVER SKINS; HUMAN SKIN; HYDROPHILIC MACROMOLECULES; HYDROPHILIC PROTEIN; IN-VITRO; NANOCARRIERS; NANOGELS; PERMEATION EXPERIMENTS; PLURONIC F-127; PLURONICS; RESERVOIR CHARACTERISTIC; SKIN PERMEATION; SOLUBLE PROTEINS; TRANSCUTANEOUS DELIVERY; TRANSDERMAL; TRANSDERMAL ADMINISTRATION; VERY LOW PERMEABILITY;

CHITOSAN; DRUG PRODUCTS; HYDROPHILICITY; MACROMOLECULES;

PROTEINS;

BETA GALACTOSIDASE; BOVINE SERUM ALBUMIN; CHITOSAN DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE; INSULIN; NANOCARRIER; POLOXAMER;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STABILITY; HISTOLOGY; HUMAN; HUMAN TISSUE; HYDROPHILICITY; IN VITRO STUDY; PRIORITY JOURNAL; SKIN PENETRATION; SKIN PERMEABILITY; STRATUM CORNEUM; SURFACE CHARGE; TRANSDERMAL DRUG ADMINISTRATION;

ADMINISTRATION, CUTANEOUS; CHITOSAN; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INSULIN; MALE; MIDDLE AGED; NANOSTRUCTURES; PERMEABILITY; POLOXAMER; SERUM ALBUMIN, BOVINE; SKIN; SKIN ABSORPTION;

EID: 84855805079     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.08.013     Document Type: Article

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