In vitro release from oil injectables for intra-articular administration: Importance of interfacial area, diffusivity and partitioning

European Journal of Pharmaceutical Sciences

Volumn 45, Issue 3, 2012, Pages 351-357

  Thing, Mette ^a   Larsen, Claus ^a   Østergaard, Jesper ^a   Jensen, Henrik ^a   Larsen, Susan Weng ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Diffusivity; In vitro release; Intra articular; Lipophilic solution; Multimodal analgesia

Indexed keywords

CASTOR OIL; DRUG VEHICLE; MEDIUM CHAIN TRIACYLGLYCEROL; NAPROXEN; PIROXICAM; ROPIVACAINE;

ARTICLE; CONCENTRATION (PARAMETERS); DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; DRUG TRANSPORT; IN VITRO STUDY; INTRAARTICULAR DRUG ADMINISTRATION; OIL FORMULATION; PH; PRIORITY JOURNAL; VISCOSITY;

AMIDES; DELAYED-ACTION PREPARATIONS; DIFFUSION; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INJECTIONS, INTRA-ARTICULAR; MODELS, CHEMICAL; NAPROXEN; OILS; PHARMACEUTICAL PREPARATIONS; PHARMACEUTICAL VEHICLES; PIROXICAM; TECHNOLOGY, PHARMACEUTICAL; VISCOSITY; WATER;

EID: 84855795838     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.12.006     Document Type: Article

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