Assessment of drug release from oil depot formulations using an in vitro model - Potential applicability in accelerated release testing

Drug Development and Industrial Pharmacy

Volumn 34, Issue 3, 2008, Pages 297-304

  Larsen, Susan Weng ^a   Jessen, Marit N B ^a   Østergaard, Jesper ^a   Larsen, Claus ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Depot formulation; In vitro release testing; Intra articular drug delivery; Oil solution; Rotating dialysis cell

Indexed keywords

BUPIVACAINE; CASTOR OIL; FLURBIPROFEN; IMWITOR 742; KETOPROFEN; LIDOCAINE; MEDIUM CHAIN TRIACYLGLYCEROL; MYRISTIC ACID ISOPROPYL ESTER; MYRITOL 318 PH; NAPROXEN; OCTANOIC ACID; OIL; PRILOCAINE; ROPIVACAINE; SALICYLAMIDE; SESAME SEED OIL; SOFTIGEN 701; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; PARAMETER; QUALITY CONTROL; REACTION ANALYSIS; REACTION TIME; ROTATION;

CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; HYDROPHOBICITY; INJECTIONS, INTRA-ARTICULAR; KINETICS; MODELS, CHEMICAL; OILS; PHARMACEUTICAL PREPARATIONS; QUALITY CONTROL; TECHNOLOGY, PHARMACEUTICAL; VEHICLES; WATER;

EID: 41149124993     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040701655994     Document Type: Article

References (25)

1. Akers, M. J. (2002). Excipient-drug interactions in parenteral formulations. J. Pharm. Sci., 91, 2283-2300.
2. Benson, H. A. E., & Prankerd, R. J. (1998). Optimisation of drug delivery. 6. Modified-release parenterals. Aust. J. Hosp. Pharm., 28, 99-104.
3. Burgess, D. J., Hussain, A. S., Ingallinera, T. S., & Chen, M. L. (2002). Assuring quality and performance of sustained and controlled release parenterals: AAPS workshop report, co-sponsored by FDA and USP. Pharm. Res., 19, 1761-1768.
4. Burgess, D. J., Crommelin, D. J. A., Hussain, A. S., & Chen, M. L. (2004a). Assuring quality and performance of sustained and controlled release parenterals. Eur. J. Pharm. Sci., 21, 679-690.
5. Burgess, D. J., Crommelin, D. J. A., Hussain, A. S., & Chen, M. L. (2004b). Assuring quality and performance of sustained and controlled release parenterals: EUFEPS workshop report. AAPS PharmSci, 6, E11.
6. Chien, Y. W. (1981). Long-acting parenteral drug formulations. J. Parenter. Sci. Technol., 35, 106-139.
7. D'Souza, S. S., & DeLuca, P. P. (2006). Methods to assess in vitro drug release from injectable polymeric particulate systems. Pharm. Res., 23, 460-474.
8. Dibbern, H. W., & Wirbitzki, E. (1983). Possibilities for determinating the active substance release from hydrophobic carriers especially as suppositories. Pharm. Ind., 45, 985-990.
9. Fredholt, K., Larsen, D. H., & Larsen, C. (2000). Modification of in vitro drug release rate from oily parenteral depots using a formulation approach. Eur J. Pharm. Sci., 11, 231-237.
10. Iyer, S. S., Barr, W. H., & Karnes, H. T. (2006). Profiling in vitro drug release from subcutaneous implants: A review of current status and potential implications on drug product development. Biopharm. Drug Dispos., 27, 157-170.
11. Larsen, D. B., Fredholt, K., & Larsen, C. (2001). Addition of hydrogen bond donating excipients to oil solution: Effect on in vitro drug release rate and viscosity. Eur. J. Pharm., Sci., 13 (4), 403-410.
12. Larsen, D. B., Parshad, H., Fredholt, K., & Larsen, C. (2002). Characteristics of drug substances in oily solutions. Drug release rate, partitioning and solubility. Int. J. Pharm., 232, 107-117.
13. Larsen, D. H., Fredholt, K., & Larsen, C. (2000). Assessment of rate of drug release from oil vehicle using a rotating dialysis cell. Eur. J. Pharm. Sci., 11, 223-229.
14. Larsen, S. W., Thomsen, A. E., Rinvar, E., Friis, G. J., & Larsen, C. (2001). Effect of drug lipophilicity on in vitro release rate from oil vehicles using nicotinic acid esters as model prodrug derivatives. Int. J. Pharm., 216, 83-93.
15. Larsen, S. W., Østergaard, J., Friberg-Johansen, H., Jessen, M. N., & Larsen, C. (2006). In vitro assessment of drug release rates from oil depot formulations intended for intra-articular administration. Eur. J. Pharm. Sci., 29, 348-354.
16. Møiniche, S., Mikkelsen, S. M., Wetterslev, J., & Dahl, J. (1999). A systemic review of intra-articular local anesthesia for postoperative pain relief after arthroscopic knee surgery. Reg. Anesth. Pain Med., 24, 430-437.
17. Østergaard, J., Larsen, S. W., Parshad, H., & Larsen, C. (2005). Bupivacaine salts of diflunisal and other aromatic hydroxycarboxylic acids: aqueous solubility and release characteristics from solutions and suspensions using a rotating dialysis cell model. Eur. J. Pharm. Sci., 26, 280-287.
18. Pedersen, B. T., Østergaard, J., Larsen, S. W., & Larsen, C. (2005). Characterization of the rotating dialysis cell as an in vitro model potentially useful for simulation of the pharmacokinetic fate of intra-articularly administered drugs. Eur. J. Pharm. Sci., 25, 73-79.
19. Simkin, P. A., Wu, M. P., & Foster, D. M. (1993). Articular pharmacokinetics of protein-bound antirheumatic agents. Clin. Pharmacokinet., 25, 342-350.
20. Strickley, R. G. (2004). Solubilizing excipients in oral and injectable formulations. Pharm. Res., 21, 201-230.
21. Wade, A., & Weller, P. J. (1994). Handbook of pharmaceutical excipients (2nd ed.). London: The Pharmaceutical Press.
22. Wallis, W. J., Simkin, P. A., & Nelp, W. B. (1987). Protein traffic in human synovial effusions. Arthritis Rheum., 30, 57-63.
23. Washington, C. (1989). Evaluation of non-sink dialysis methods for the measurement of drug release from colloids: Effects of drug partition. Int. J. Pharm., 56, 71-74.
24. Washington, C. (1990). Drug release from microdisperse systems: A critical review. Int. J. Pharm., 58, 1-12.
25. Zuidema, J., Kadir, F., Titulaer, H. A. C., & Oussoren, C. (1994). Release and absorption rates of intramuscularly and subcutaneously injected pharmaceuticals (II). Int. J. Pharm., 105, 189-207.