In vitro assessment of drug release rates from oil depot formulations intended for intra-articular administration

European Journal of Pharmaceutical Sciences

Volumn 29, Issue 5, 2006, Pages 348-354

  Larsen, Susan Weng ^a   Østergaard, Jesper ^a   Friberg Johansen, Henrik ^a   Jessen, Marit N B ^a   Larsen, Claus ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Depot formulation; Diffusion; Drug release; Intra articular drug delivery; Oil solution; Rotating dialysis cell

Indexed keywords

ATENOLOL; LIDOCAINE; NAPROXEN; SESAME SEED OIL; WATER;

ARTICLE; COMPARTMENT MODEL; DRUG ADMINISTRATION ROUTE; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG RELEASE; IN VITRO STUDY; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; SOLUBILITY;

DELAYED-ACTION PREPARATIONS; DIALYSIS; HYDROGEN-ION CONCENTRATION; INJECTIONS, INTRA-ARTICULAR; KINETICS; LIDOCAINE; MODELS, BIOLOGICAL; NAPROXEN; ROTATION; SESAME OIL;

EID: 33750694953     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2006.07.002     Document Type: Article

References (21)

1. Benson H.A.E., and Prankerd R.J. Optimisation of drug delivery. 6. Modified-release parenterals. Aust. J. Hosp. Pharm. 28 (1998) 99-104
2. Burgess D.J., Hussain A.S., Ingallinera T.S., and Chen M.-L. Assuring quality and performance of sustained and controlled release parenterals: workshop report, co-sponsored by FDA and USP. Pharm. Res. 19 (2002) 1761-1768
3. Burgess, D.J., Crommelin, D.J.A., Hussain, A.S., Chen, M.-L., 2004. Assuring quality and performance of sustained and controlled release parenterals: EUFEPS workshop report. AAPS PharmSci. 6, article 11.
4. Chien Y.M. Long-acting parenteral drug formulations. J. Parenter. Sci. Technol. 35 (1981) 106-139
5. Dibbern H.W., and Wirbitzki E. Possibilities for determinating the active substance release from hydrophobic carriers especially as suppositories. Pharm. Ind. 45 (1983) 985-990
6. Elmquist W.E., Chan K.K.H., and Sawchuk R.J. Transsynovial drug distribution: synovial mean transit time of diclofenac and other non-steroidal anti-inflammatory drugs. Pharm. Res. 11 (1994) 1689-1697
7. Florence A.T., and Attwood D. Physicochemical Principles of Pharmacy. 3rd ed. (1998), Palgrave, Houndmills, England pp. 183-186
8. Fredholt K., Larsen D.H., and Larsen C. Modification of in vitro drug release rate from oily parenteral depots using a formulation approach. Eur. J. Pharm. Sci. 11 (2000) 231-237
9. Hirano K., Ichihashi T., and Yamada H. Studies on the absorption of practically water-insoluble drugs following injection. I. Intramuscular absorption from water-immiscible oil solutions in rats. Chem. Pharm. Bull. 29 (1981) 519-531
10. Hirano K., Ichihashi T., and Yamada H. Studies on the absorption of practically water-insoluble drugs following injection V: subcutaneous absorption in rats from solutions in water immiscible oils. J. Pharm. Sci. 71 (1982) 495-500
11. Hunneyball I.M. Intra-articular administration of drugs. Pharm. Int. 5 (1986) 118-122
12. Larsen D.H., Fredholt K., and Larsen C. Assessment of rate of drug release from oil vehicle using a rotating dialysis cell. Eur. J. Pharm. Sci. 11 (2000) 223-229
13. Larsen D.B., Parshad H., Fredholt K., and Larsen C. Characteristics of drug substances in oily solutions. Drug release rate, partitioning and solubility. Int. J. Pharm. 232 (2002) 107-117
14. Østergaard J., Larsen S.W., Parshad H., and Larsen C. Bupivacaine salts of diflunisal and other aromatic hydroxycarboxylic acids: aqueous solubility and release characteristics from solutions and suspensions using a rotating dialysis cell model. Eur. J. Pharm. Sci. 26 (2005) 280-287
15. Pedersen B.T., Østergaard J., Larsen S.W., and Larsen C. Characterization of the rotating dialysis cell as an in vitro model potentially useful for simulation of the pharmacokinetic fate of intra-articularly administered drugs. Eur. J. Pharm. Sci. 25 (2005) 73-79
16. Rotonda M.I.L., Cappello B., Grimaldi M., Silipo C., and Vittoria A. Analisi correlative fra bilancio idrofilo-lipofilo, coefficiente di diffusione e concentrazione idrogenionica in una serie di farmaci antiinfiammatori non steroidei. Farmaco Ed. Sci. 43 (1988) 439-456
17. Sasaki H., Takakura Y., Hashida M., Kimura T., and Sezaki H. Antitumor activity of lipophilic prodrugs of mitomycin C entrapped in liposome or O/W emulsion. J. Pharm. Dyn. 7 (1984) 120-130
18. Simkin P.A., Wu M.P., and Foster D.M. Articular pharmacokinetics of protein-bound antirheumatic agents. Clin. Pharmacokinet. 25 (1993) 342-350
19. Wallis W.J., and Simkin P.A. Antirheumatic drug concentrations in human synovial fluid and synovial tissue. Observations on extravascular pharmacokinetics. Clin. Pharmacokinet. 8 (1983) 496-522
20. Yunker M.H., and Borodkin S. Determination of rate constants for in vitro three-compartment transfer using a two-phase system. J. Pharm. Sci. 60 (1971) 52-56
21. Zuidema J., Kadir F., Titulaer H.A.C., and Oussoren C. Release and absorption rates of intramuscularly and subcutaneously injected pharmaceuticals (II). Int. J. Pharm. 105 (1994) 189-207