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European Journal of Medicinal Chemistry

Volumn 47, Issue 1, 2012, Pages 424-431

Design, synthesis and biological evaluation of novel glycosylated diphyllin derivatives as topoisomerase II inhibitors

(5) Shi, Da Kuo a Zhang, Wei b Ding, Ning b Li, Ming a Li, Ying Xia b

a OCEAN UNIVERSITY OF CHINA (China)

b FUDAN UNIVERSITY (China)

Author keywords

Anticancer; Diphyllin; Structure activity relationship; Synthesis; Topo II inhibitors

Indexed keywords

4 O ALPHA ARABINOSYLDIPHYLLIN; 4 O BETA DEXTRO FUCOPYRANOSYLDIPHYLLIN; 4 O BETA DEXTRO GALACTOPYRANOSYLDIPHYLLIN; 4 O BETA DEXTRO GLUCOPYRANOSYLDIPHYLLIN; 4 O BETA DEXTRO XYLOSYLDIPHYLLIN; 4',6' ACETONIDE 4 O BETA DEXTRO GLUCOPYRANOSYLDIPHYLLIN; 4',6' ETHYDENIDE 4 O BETA DEXTRO GLUCOPYRANOSYLDIPHYLLIN; 4',6' ISOBUTYLDENIDE 4 O BETA DEXTRO GLUCOPYRANOSYLDIPHYLLIN; 6' O BENZYL 4 O BETA DEXTRO GALACTOPYRANOSYLDIPHYLLIN; 6' O BENZYL 4 O BETA DEXTRO GLUCOPYRANOSYLDIPHYLLIN; 6' O METHYL 4 O BETA DEXTRO GALACTOPYRANOSYLDIPHYLLIN; 6' O METHYL 4 O BETA DEXTRO GLUCOPYRANOSYLDIPHYLLIN; ANTINEOPLASTIC AGENT; DIPROPHYLLINE; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; GLYCOSYLATED DIPHYLLIN DERIVATIVE; GYRASE INHIBITOR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN MCF 7; COLON CARCINOMA; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DIOXOLANES; DNA FRAGMENTATION; DNA TOPOISOMERASES, TYPE II; DRUG DESIGN; DRUG RESISTANCE, MULTIPLE; GLYCOSYLATION; HUMANS; LIGNANS; STRUCTURE-ACTIVITY RELATIONSHIP; TOPOISOMERASE II INHIBITORS;

EID: 84855780553 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.11.011 Document Type: Article

Times cited : (28)

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