Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 35, 2005, Pages 12305-12310

  Langenhan, Joseph M ^a   Peters, Noël R ^b   Guzei, Ilia A ^a   Hoffmann, F Michael ^a,b   Thorson, Jon S ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

Author keywords

Carbohydrate; Natural product; Sugar

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARBOHYDRATE DERIVATIVE; CARDIAC GLYCOSIDE; DIGOXIN; NATURAL PRODUCT;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG SPECIFICITY; ENZYME INHIBITION; GLYCOBIOLOGY; GLYCOSYLATION; HUMAN; HUMAN CELL; IC 50; NEOGLYCORANDOMIZATION; NONHUMAN; PRIORITY JOURNAL; RELIABILITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CARDIAC GLYCOSIDES; CELL LINE, TUMOR; DIGITOXIN; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG STABILITY; ENZYME INHIBITORS; GLYCOSYLATION; HUMANS; HYDROLYSIS; MICE; MOLECULAR STRUCTURE; NA(+)-K(+)-EXCHANGING ATPASE;

EID: 24644484805     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0503270102     Document Type: Article

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