Novel diamino imidazole and pyrrole-containing polyamides: Synthesis and DNA binding studies of mono- and diamino-phenyl-ImPyIm polyamides designed to target 5′-ACGCGT-3′

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 2, 2012, Pages 693-701

  Satam, Vijay ^a   Babu, Balaji ^a   Chavda, Sameer ^a   Savagian, Mia ^a   Sjoholm, Robert ^a   Tzou, Samuel ^a   Liu, Yang ^b   Kiakos, Konstantinos ^c   Lin, Shicai ^c   David Wilson, W ^b   Hartley, John A ^c   Lee, Moses ^a  

^a HOPE COLLEGE   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

ACGCGT; Cell cycle box; Diamino; Dicationic; Gene control; MCB; Mlu1; Polyamides

Indexed keywords

4 BENZAMIDO 1 METHYLIMIDAZOLE 2 CARBOXYLIC ACID; AMINO TERMINAL TELOPEPTIDE; DEOXYRIBONUCLEASE I; DIAMINO PHENYL IMIDAZOLEPYRROLEIMIDAZOLE POLYAMIDE; ETHYL 4 BENZAMIDO 1 METHYLIMIDAZOLE 2 CARBOXYLATE; IMIDAZOLE DERIVATIVE; MONOAMINO PHENYL IMIDAZOLEPYRROLEIMIDAZOLE POLYAMIDE; POLYAMIDE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

AFFINITY LABELING; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; DENATURATION; DNA BINDING; DNA FOOTPRINTING; DNA SEQUENCE; DNA SYNTHESIS;

BASE SEQUENCE; BENZAMIDES; CALORIMETRY; CIRCULAR DICHROISM; DEOXYRIBONUCLEASE I; DISTAMYCINS; DNA; IMIDAZOLES; NYLONS; PYRROLES; SURFACE PLASMON RESONANCE;

EID: 84855774423     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.12.010     Document Type: Article

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