Hx, a novel fluorescent, minor groove and sequence specific recognition element: Design, synthesis, and DNA binding properties of p - anisylbenzimidazole-imidazole/pyrrole-containing polyamides

Biochemistry

Volumn 50, Issue 15, 2011, Pages 3127-3136

  Chavda, Sameer ^a   Liu, Yang ^b   Babu, Balaji ^a   Davis, Ryan ^a   Sielaff, Alan ^a   Ruprich, Jennifer ^a   Westrate, Laura ^a   Tronrud, Christopher ^a   Ferguson, Amanda ^a   Franks, Andrew ^a   Tzou, Samuel ^a   Adkins, Chandler ^d   Rice, Toni ^a   MacKay, Hilary ^a   Kluza, Jerome ^c   Tahir, Sharjeel A ^c   Lin, Shicai ^c   Kiakos, Konstantinos ^c   Bruce, Chrystal D ^d   Wilson, W David ^b   Hartley, John A ^c   Lee, Moses ^a   more..

^a HOPE COLLEGE   (United States)

^b GEORGIA STATE UNIVERSITY   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d Erskine College   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; BINDING CONSTANT; BINDING DATA; BIOPHYSICAL CHARACTERIZATION; CIRCULAR DICHROISM; DENSITY-FUNCTIONAL CALCULATIONS; DISTAMYCIN; DNA RECOGNITION; DNA-BINDING PROPERTIES; ELECTROSTATIC SURFACES; FLUORESCENT PROBES; FOOTPRINTING; IN-CELL; ISOTHERMAL TITRATION CALORIMETRY; LOW MOLECULAR WEIGHT; MINOR GROOVES; RECOGNITION ELEMENT; SPECIFIC RECOGNITION; THEORETICAL FRAMEWORK; TRIAMIDES;

AMIDES; BINDING ENERGY; DENSITY FUNCTIONAL THEORY; DICHROISM; DNA; FLUORESCENCE; IODINE; NUCLEIC ACIDS; POLYAMIDES; POTASSIUM COMPOUNDS; PROBES; SURFACE PLASMON RESONANCE;

DNA SEQUENCES;

4 ANISYLBENZIMIDAZOLECARBOXAMIDO; AMIDE; DEOXYRIBONUCLEASE I; DISTAMYCIN A; IMIDAZOLE; POLYAMIDE; PYRROLE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CELL ACTIVITY; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CONCEPTUAL FRAMEWORK; DENSITY FUNCTIONAL THEORY; DNA BINDING; DNA FOOTPRINTING; DNA SEQUENCE; FLUORESCENCE; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR MODEL; MOLECULAR WEIGHT; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE; SYNTHESIS; THERMAL ANALYSIS;

BASE SEQUENCE; CALORIMETRY; CIRCULAR DICHROISM; DEOXYRIBONUCLEASE I; DNA; DRUG DESIGN; FLUORESCENT DYES; IMIDAZOLES; MICROCOCCAL NUCLEASE; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NYLONS; PYRROLES; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE;

EID: 79953878855     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi102028a     Document Type: Article

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