14-3-3σ regulation by p53 mediates a chemotherapy response to 5-fluorouracil in MCF-7 breast cancer cells via Akt inactivation

FEBS Letters

Volumn 586, Issue 2, 2012, Pages 163-168

  Zheng, Guopei ^b   Xiong, Yan ^a   Yi, Sisi ^b   Zhang, Weijia ^b   Peng, Bo ^b   Zhang, Qiong ^a   He, Zhimin ^a,b  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b Central South University   (China)

Author keywords

14 3 3 ; Akt; Breast cancer; Drug resistance; Methylation; p53

Indexed keywords

CISPLATIN; FLUOROURACIL; MITOXANTRONE; NUCLEAR FACTOR KAPPA B P50; NUCLEIC ACID BINDING PROTEIN; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; STRATIFIN; SURVIVIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; DRUG MECHANISM; DRUG RESPONSE; DRUG SENSITIVITY; DRUG TARGETING; ENZYME INACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; STABLE EXPRESSION;

14-3-3 PROTEINS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BIOMARKERS, PHARMACOLOGICAL; BREAST NEOPLASMS; CARCINOMA; CELL LINE, TUMOR; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; EXONUCLEASES; FEMALE; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ONCOGENE PROTEIN V-AKT; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84855763598     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.11.034     Document Type: Article

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