The protective effect of tianeptine on Gp120-induced apoptosis in astroglial cells: Role of GS and NOS, and NF-κB suppression

British Journal of Pharmacology

Volumn 164, Issue 6, 2011, Pages 1590-1599

  Janda, Elzbieta ^a   Visalli, Valeria ^a,b   Colica, Carmela ^c   Aprigliano, Serafina ^a   Musolino, Vincenzo ^a   Vadalà, Nuria ^a   Muscoli, Carolina ^a   Sacco, Iolanda ^b   Iannone, Michelangelo ^b   Rotiroti, Domenicantonio ^a   Spedding, Michael ^d   Mollace, Vincenzo ^a,b  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b Dipartimento Provinciale di Crotone Coordinamento attività SIN Servizio Tematico Aerea   (Italy)

^c CNR   (Italy)

^d Experimental Sciences Institute of Research   (France)

Author keywords

antidepressant drugs; apoptosis; inflammation; molecular pharmacology; neuroprotective drugs; nitric oxide

Indexed keywords

CASPASE 3; GLUTAMATE AMMONIA LIGASE; GLYCOPROTEIN GP 120; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; TIANEPTINE;

APOPTOSIS; ARTICLE; ASTROCYTE; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; ENZYME STABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE DEGENERATION; NEUROMODULATION; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BLOCKING;

APOPTOSIS; ASTROCYTES; CASPASE 3; CELL LINE, TUMOR; GLUTAMATE-AMMONIA LIGASE; GLUTAMINE; HIV ENVELOPE PROTEIN GP120; HUMANS; I-KAPPA B PROTEINS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; NITRIC OXIDE SYNTHASE; NITRITES; RECOMBINANT PROTEINS; THIAZEPINES;

EID: 80054970503     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01172.x     Document Type: Article

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