Different molecular expression in thymoma with ocular or generalized myasthenia gravis

Journal of the Neurological Sciences

Volumn 313, Issue 1-2, 2012, Pages 27-31

  Zhang, Min ^a   Li, Hongzeng ^a   Guo, Jun ^a   Zhou, Yongan ^a   Gong, Li ^a   Wang, Xianni ^a   Li, Zhuyi ^a   Zhang, Wei ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Generalized myasthenia gravis; Immunohistochemistry; Ocular myasthenia gravis; Thymoma

Indexed keywords

CD4 ANTIGEN; CXCL13 CHEMOKINE; INTERLEUKIN 2 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3;

ADULT; AGED; ARTICLE; FEMALE; GENERALIZED MYASTHENIA GRAVIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MYASTHENIA GRAVIS; OCULAR MYASTHENIA GRAVIS; ONSET AGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; THYMOMA;

ADULT; AGED; CHEMOKINE CXCL13; DOWN-REGULATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; MYASTHENIA GRAVIS; OCULAR MOTILITY DISORDERS; THYMOMA; THYMUS NEOPLASMS; UP-REGULATION; YOUNG ADULT;

EID: 84855609759     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2011.09.037     Document Type: Article

References (27)

1. Y.H. Hong, S.B. Kwon, B.J. Kim, B.J. Kim, S.H. Kim, and J.K. Kim Prognosis of ocular myasthenia in Korea: a retrospective multicenter analysis of 202 patients J Neurol Sci 273 2008 10 14
2. D. Grob, N. Brunner, T. Namba, and M. Pagala Lifetime course of myasthenia gravis Muscle Nerve 37 2008 141 149 (Pubitemid 351214160)
3. C.L. Williams, J.E. Hay, T.W. Huiatt, and V.A. Lennon Paraneoplastic IgG striational autoantibodies produced by clonal thymic B cells and in serum of patients with myasthenia gravis and thymoma react with titin Lab Invest 66 1992 331 336
4. K. Kondo Optimal therapy for thymoma J Med Invest 55 2008 17 28 (Pubitemid 351643589)
5. A. Marx, A. Wilisch, A. Schultz, S. Gattenlohner, R. Nenninger, and H.K. Muller-Hermelink Pathogenesis of myasthenia gravis Virchows Arch 430 1997 355 364 (Pubitemid 27202101)
6. + T regulatory cells Nat Immunol 4 2003 337 342 (Pubitemid 36432315)
7. + regulatory T cells Nat Immunol 4 2003 330 336 (Pubitemid 36432314)
8. S. Hori, T. Nomura, and S. Sakaguchi Control of regulatory T cell development by the transcription factor Foxp3 Science 299 2003 1057 1061 (Pubitemid 36222930)
9. A. Fattorossi, A. Battaglia, A. Buzzonetti, F. Ciaraffa, G. Scambia, and A. Evoli Circulating and thymic CD4 CD25 T regulatory cells in myasthenia gravis: effect of immunosuppressive treatment Immunology 116 2005 134 141 (Pubitemid 41208360)
10. A. Balandina, S. Lecart, P. Dartevelle, A. Saoudi, and S. Berrih-Aknin Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis Blood 105 2005 735 741 (Pubitemid 40070760)
11. + T cells in myasthenia gravis patients with stability and thymectomy Clin Immunol 112 2004 284 289 (Pubitemid 39078704)
12. + T cells in myasthenia gravis and in relation to thymectomy Scand J Immunol 59 2004 408 414 (Pubitemid 38482525)
13. H.S. Carlsen, E.S. Baekkevold, F.E. Johansen, G. Haraldsen, and P. Brandtzaeg B cell attracting chemokine 1 (CXCL13) and its receptor CXCR5 are expressed in normal and aberrant gut associated lymphoid tissue Gut 51 2002 364 371
14. S.A. Luther, K.M. Ansel, and J.G. Cyster Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development J Exp Med 197 2003 1191 1198 (Pubitemid 36570074)
15. D.F. Legler, M. Loetscher, R.S. Roos, I. Clark-Lewis, M. Baggiolini, and B. Moser B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5 J Exp Med 187 1998 655 660 (Pubitemid 28093368)
16. G. Aust, D. Sittig, L. Becherer, U. Anderegg, A. Schutz, and P. Lamesch The role of CXCR5 and its ligand CXCL13 in the compartmentalization of lymphocytes in thyroids affected by autoimmune thyroid diseases Eur J Endocrinol 150 2004 225 234 (Pubitemid 38312815)
17. A. Meraouna, G. Cizeron-Clairac, R.L. Panse, J. Bismuth, F. Truffault, and C. Tallaksen The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis Blood 108 2006 432 440 (Pubitemid 44061339)
18. Y.M. Shiao, C.C. Lee, Y.H. Hsu, S.F. Huang, C.Y. Lin, and L.H. Li Ectopic and high CXCL13 chemokine expression in myasthenia gravis with thymic lymphoid hyperplasia J Neuroimmunol 221 2010 101 106
19. P. Gajdos, C. Tranchant, B. Clair, F. Bolgert, B. Eymard, and T. Stojkovic Treatment of myasthenia gravis exacerbation with intravenous immunoglobulin: a randomized double-blind clinical trial Arch Neurol 62 2005 1689 1693 (Pubitemid 41626664)
20. A.R. Jaretzki, R.J. Barohn, R.M. Ernstoff, H.J. Kaminski, J.C. Keesey, and A.S. Penn Myasthenia gravis: recommendations for clinical research standards. Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America Neurology 55 2000 16 23
21. F. Dadmanesh, T. Sekihara, and J. Rosai Histologic typing of thymoma according to the new World Health Organization classification Chest Surg Clin N Am 11 2001 407 420 (Pubitemid 32531721)
22. S. Suzuki, K. Utsugisawa, Y. Nagane, T. Satoh, M. Kuwana, and N. Suzuki Clinical and immunological differences between early and late-onset myasthenia gravis in Japan J Neuroimmunol 230 2011 148 152
23. R. Beekman, J.B. Kuks, and H.J. Oosterhuis Myasthenia gravis: diagnosis and follow-up of 100 consecutive patients J Neurol 244 1997 112 118 (Pubitemid 27057957)
24. J.A. Aarli Late-onset myasthenia gravis: a changing scene Arch Neurol 56 1999 25 27 (Pubitemid 29046905)
25. + CD25hi Tregs in the pathogenesis of myasthenia gravis Immunol Lett 122 2009 52 57
26. A. Fattorossi, A. Battaglia, A. Buzzonetti, G. Minicuci, R. Riso, and L. Peri Thymopoiesis, regulatory T cells, and TCRVbeta expression in thymoma with and without myasthenia gravis, and modulatory effects of steroid therapy J Clin Immunol 28 2008 194 206
27. J.E. Talmadge, M. Donkor, and E. Scholar Inflammatory cell infiltration of tumors: Jekyll or Hyde Cancer Metastasis Rev 26 2007 373 400 (Pubitemid 350115102)