Transcriptional activation of inflammasome components by Libby amphibole and the role of iron

Inhalation Toxicology

Volumn 24, Issue 1, 2012, Pages 60-69

  Shannahan, J H ^a   Ghio, A J ^b   Schladweiler, M C ^b   Richards, J H ^b   Andrews, D ^b   Gavett, S H ^b   Kodavanti, U P ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Inflammasome; Iron; Libby amphibole; Lung inflammation

Indexed keywords

AMPHIBOLE; CATHEPSIN B; CRYOPYRIN; CXCL3 CHEMOKINE; CYCLOOXYGENASE 2 INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 6; IRON; LUNG ENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 3; MONOCYTE CHEMOTACTIC PROTEIN 5;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FIBROSIS; KOLETSKY RAT; LUNG LAVAGE; MALE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; ASBESTOS, AMPHIBOLE; BRONCHOALVEOLAR LAVAGE FLUID; CHLORIDES; CYTOKINES; DEFEROXAMINE; FERRIC COMPOUNDS; INFLAMMASOMES; LUNG; MALE; RATS; RATS, INBRED SHR; RNA, MESSENGER; SIDEROPHORES; TRANSCRIPTIONAL ACTIVATION;

RATTUS;

EID: 84855491363     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2011.633942     Document Type: Article

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