p38 and Src-ERK1/2 pathways regulate crystalline silica-induced chemokine release in pulmonary epithelial cells

Toxicological Sciences

Volumn 81, Issue 2, 2004, Pages 480-490

  Øvrevik, Johan ^a   Låg, Marit ^a   Schwarze, Per ^a   Refsnes, Magne ^a  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

Author keywords

Interleukin 8; Macrophage inflammatory protein 2; Mitogen activated protein kinases; Protein tyrosine kinases; Quartz

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHEMOKINE; GENISTEIN; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SILICON DIOXIDE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ANIMAL CELL; ARTICLE; CELL LINE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; EPITHELIUM CELL; EXPOSURE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; LUNG DISEASE; MOLECULAR MECHANICS; NONHUMAN; PROTEIN INDUCTION; RAT; SIGNAL TRANSDUCTION; TIME;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITORS; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; IMIDAZOLES; INTERLEUKIN-8; LUNG; MONOKINES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; RATS; SIGNAL TRANSDUCTION; SILICON DIOXIDE; SRC-FAMILY KINASES;

EID: 5744254899     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh214     Document Type: Article

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