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Volumn 56, Issue 48, 2000, Pages 9503-9513

Protein backbone engineering through total chemical synthesis: New insight into the mechanism of HIV-1 protease catalysis

(2) Baca, Manuel a Kent, Stephen B H b

a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (Australia)

b Gryphon Therapeutics (United States)

Author keywords

Backbone engineering; Chemical ligation; Chemical protein synthesis; Enzyme mechanism; HIV 1 protease; Hydrogen bond; Thioester; Unprotected peptide segments

Indexed keywords

PROTEINASE;

ARTICLE; CATALYSIS; CATALYST; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENETIC ENGINEERING; PRIORITY JOURNAL; SYNTHESIS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0034711433 PISSN: 00404020 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4020(00)00835-8 Document Type: Article

Times cited : (26)

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