DNA double-strand breaks induced by high NaCl occur predominantly in gene deserts

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 51, 2011, Pages 20796-20801

  Dmitrieva, Natalia I ^a   Cui, Kairong ^a   Kitchaev, Daniil A ^b   Zhao, Keji ^a   Burg, Maurice B ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b California Institute of Technology   (United States)

Author keywords

DNA damage; Hypertonicity; Kidney; mIMCD3 cells; Salt

Indexed keywords

ATM PROTEIN; ATR PROTEIN; HISTONE GAMMA H2AX; HISTONE H2AX; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DNA FRAGMENTATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENE CLUSTER; GENE DESERT; GENE STRUCTURE; GENOME; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSMOLALITY; PRIORITY JOURNAL;

ANIMALS; BLEOMYCIN; COMET ASSAY; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA FRAGMENTATION; DNA REPAIR ENZYMES; HISTONES; KIDNEY; MICE; MODELS, GENETIC; OXIDANTS; PHOSPHORYLATION; RADIATION, IONIZING; SODIUM CHLORIDE; ULTRAVIOLET RAYS;

ANIMALIA;

EID: 84855477045     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114677108     Document Type: Article

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