Dose-dependent effects of genistein on bone homeostasis in rats' mandibular subchondral bone

Acta Pharmacologica Sinica

Volumn 33, Issue 1, 2012, Pages 66-74

  Li, Yong Qi ^a   Xing, Xiang Hui ^b   Wang, Hui ^b   Weng, Xi Li ^b   Yu, Shi Bin ^b   Dong, Guang Ying ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

alkaline phosphatase; estrogen receptor; genistein; mandibular subchondral bone; osteoblast; osteocalcin; osteoprotegerin; the receptor activator of nuclear factor B ligand (RANKL)

Indexed keywords

ALKALINE PHOSPHATASE; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR BETA; GENISTEIN; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PLACEBO;

ARTICLE; BONE DENSITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; FEEDING; FEMALE; HOMEOSTASIS; IN VITRO STUDY; IN VIVO CULTURE; IN VIVO STUDY; LOW DRUG DOSE; MANDIBLE; MANDIBLE CONDYLE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRABECULAR BONE;

ALKALINE PHOSPHATASE; ANIMALS; BONE DENSITY; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; GENISTEIN; HOMEOSTASIS; HUMANS; MANDIBULAR CONDYLE; OSTEOBLASTS; OSTEOCALCIN; OSTEOPROTEGERIN; PHYTOESTROGENS; RANDOM ALLOCATION; RANK LIGAND; RATS; RATS, SPRAGUE-DAWLEY; X-RAY MICROTOMOGRAPHY;

EID: 84855472256     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.136     Document Type: Article

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