메뉴 건너뛰기




Volumn 13, Issue 12, 2011, Pages 1132-1142

Identification of MET and SRC activation in melanoma cell lines showing primary resistance to PLX4032

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR; VEMURAFENIB;

EID: 84855460594     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.111102     Document Type: Article
Times cited : (85)

References (51)
  • 1
    • 33846201272 scopus 로고    scopus 로고
    • New insight into BRAF mutations in cancer
    • Dhomen N and Marais R (2007). New insight into BRAF mutations in cancer. Curr Opin Genet Dev 17, 31-39.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 31-39
    • Dhomen, N.1    Marais, R.2
  • 2
    • 58649110598 scopus 로고    scopus 로고
    • Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
    • Zheng B, Jeong JH, Asara JM, Yuan YY, Granter SR, Chin L, and Cantley LC (2009). Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation. Mol Cell 33, 237-247.
    • (2009) Mol Cell , vol.33 , pp. 237-247
    • Zheng, B.1    Jeong, J.H.2    Asara, J.M.3    Yuan, Y.Y.4    Granter, S.R.5    Chin, L.6    Cantley, L.C.7
  • 3
    • 80052358465 scopus 로고    scopus 로고
    • Treatment implications of the emerging molecular classification system for melanoma
    • Romano E, Schwartz GK, Chapman PB, Wolchock JD, and Carvajal RD (2011). Treatment implications of the emerging molecular classification system for melanoma. Lancet Oncol 12, 913-922.
    • (2011) Lancet Oncol , vol.12 , pp. 913-922
    • Romano, E.1    Schwartz, G.K.2    Chapman, P.B.3    Wolchock, J.D.4    Carvajal, R.D.5
  • 4
    • 47249097988 scopus 로고    scopus 로고
    • BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells
    • Sala E, Mologni L, Truffa S, Gaetano C, Bollag GE, and Gambacorti-Passerini C (2008). BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells. Mol Cancer Res 6, 751-759.
    • (2008) Mol Cancer Res , vol.6 , pp. 751-759
    • Sala, E.1    Mologni, L.2    Truffa, S.3    Gaetano, C.4    Bollag, G.E.5    Gambacorti-Passerini, C.6
  • 5
    • 77954376912 scopus 로고    scopus 로고
    • RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models
    • Yang H, Higgins B, Kolinsky K, Packman K, Go Z, Iyer R, Kolis S, Zhao S, Lee R, Grippo JF, et al. (2010). RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models. Cancer Res 70, 5518-5527.
    • (2010) Cancer Res , vol.70 , pp. 5518-5527
    • Yang, H.1    Higgins, B.2    Kolinsky, K.3    Packman, K.4    Go, Z.5    Iyer, R.6    Kolis, S.7    Zhao, S.8    Lee, R.9    Grippo, J.F.10
  • 19
    • 77957894168 scopus 로고    scopus 로고
    • Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line
    • Caccia D, Micciche F, Cassinelli G, Mondellini P, Casalini P, and Bongarzone I (2010). Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line. Mol Cancer 9, 278.
    • (2010) Mol Cancer , vol.9 , pp. 278
    • Caccia, D.1    Micciche, F.2    Cassinelli, G.3    Mondellini, P.4    Casalini, P.5    Bongarzone, I.6
  • 20
    • 16844377625 scopus 로고    scopus 로고
    • Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839
    • Zanchi C, Zuco V, Lanzi C, Supino R, and Zunino F (2005). Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839. Cancer Res 65, 2364-2372.
    • (2005) Cancer Res , vol.65 , pp. 2364-2372
    • Zanchi, C.1    Zuco, V.2    Lanzi, C.3    Supino, R.4    Zunino, F.5
  • 22
    • 0035881280 scopus 로고    scopus 로고
    • A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line
    • Perego P, De Cesare M, De Isabella P, Carenini N, Beggiolin G, Pezzoni G, Palumbo M, Tartaglia L, Pratesi G, Pisano C, et al. (2001). A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line. Cancer Res 61, 6034-6037.
    • (2001) Cancer Res , vol.61 , pp. 6034-6037
    • Perego, P.1    de Cesare, M.2    de Isabella, P.3    Carenini, N.4    Beggiolin, G.5    Pezzoni, G.6    Palumbo, M.7    Tartaglia, L.8    Pratesi, G.9    Pisano, C.10
  • 31
    • 33646145930 scopus 로고    scopus 로고
    • BRAF and c-kit gene copy number in mutation-positive malignant melanoma
    • Willmore-Payne C, Holden JA, Hirschowitz S, and Layfield LJ (2006). BRAF and c-kit gene copy number in mutation-positive malignant melanoma. Hum Pathol 37, 520-527.
    • (2006) Hum Pathol , vol.37 , pp. 520-527
    • Willmore-Payne, C.1    Holden, J.A.2    Hirschowitz, S.3    Layfield, L.J.4
  • 32
    • 78649436372 scopus 로고    scopus 로고
    • BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation
    • ra84
    • Corcoran RB, Dias-Santagata D, Bergethon K, Iafrate AJ, Settleman J, and Engelman JA (2010). BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation. Sci Signal 3, ra84.
    • (2010) Sci Signal , vol.3
    • Corcoran, R.B.1    Dias-Santagata, D.2    Bergethon, K.3    Iafrate, A.J.4    Settleman, J.5    Engelman, J.A.6
  • 35
    • 63949083853 scopus 로고    scopus 로고
    • Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib
    • Lemos C, Kathmann I, Giovannetti E, Calhau C, Jansen G, and Peters GJ (2009). Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib. Br J Cancer 100, 1120-1127.
    • (2009) Br J Cancer , vol.100 , pp. 1120-1127
    • Lemos, C.1    Kathmann, I.2    Giovannetti, E.3    Calhau, C.4    Jansen, G.5    Peters, G.J.6
  • 36
    • 49649092403 scopus 로고    scopus 로고
    • Detection of copy number alterations in metastatic melanoma by a DNA fluorescence in situ hybridization probe panel and array comparative genomic hybridization: A Southwest Oncology Group study (S9431)
    • Moore SR, Persons DL, Sosman JA, Bobadilla D, Bedell V, Smith DD, Wolman SR, Tuthill RJ, Moon J, Sondak VK, et al. (2008). Detection of copy number alterations in metastatic melanoma by a DNA fluorescence in situ hybridization probe panel and array comparative genomic hybridization: a Southwest Oncology Group study (S9431). Clin Cancer Res 14, 2927-2935.
    • (2008) Clin Cancer Res , vol.14 , pp. 2927-2935
    • Moore, S.R.1    Persons, D.L.2    Sosman, J.A.3    Bobadilla, D.4    Bedell, V.5    Smith, D.D.6    Wolman, S.R.7    Tuthill, R.J.8    Moon, J.9    Sondak, V.K.10
  • 37
    • 20344402566 scopus 로고    scopus 로고
    • Additional cyclin D(1) gene copies associated with chromosome 11 aberrations in cutaneous malignant melanoma
    • Utikal J, Udart M, Leiter U, Peter RU, and Krahn G (2005). Additional cyclin D(1) gene copies associated with chromosome 11 aberrations in cutaneous malignant melanoma. Int J Oncol 26, 597-605.
    • (2005) Int J Oncol , vol.26 , pp. 597-605
    • Utikal, J.1    Udart, M.2    Leiter, U.3    Peter, R.U.4    Krahn, G.5
  • 38
    • 25644446211 scopus 로고    scopus 로고
    • Genome profiling of melanocytic tumors using multiplex ligationdependent probe amplification (MLPA): Its usefulness as an adjunctive diagnostic tool for melanocytic tumors
    • Takata M, Suzuki T, Ansai S, Kimura T, Shirasaki F, Hatta N, and Saida T (2005). Genome profiling of melanocytic tumors using multiplex ligationdependent probe amplification (MLPA): its usefulness as an adjunctive diagnostic tool for melanocytic tumors. J Dermatol Sci 40, 51-57.
    • (2005) J Dermatol Sci , vol.40 , pp. 51-57
    • Takata, M.1    Suzuki, T.2    Ansai, S.3    Kimura, T.4    Shirasaki, F.5    Hatta, N.6    Saida, T.7
  • 40
    • 77952818892 scopus 로고    scopus 로고
    • Inhibition of c-met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma
    • Kenessey I, Keszthelyi M, Kramer Z, Berta J, Adam A, Dobos J, Mildner M, Flachner B, Cseh S, Barna G, et al. (2010). Inhibition of c-met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma. Curr Cancer Drug Targets 10, 332-342.
    • (2010) Curr Cancer Drug Targets , vol.10 , pp. 332-342
    • Kenessey, I.1    Keszthelyi, M.2    Kramer, Z.3    Berta, J.4    Adam, A.5    Dobos, J.6    Mildner, M.7    Flachner, B.8    Cseh, S.9    Barna, G.10
  • 41
    • 76749107447 scopus 로고    scopus 로고
    • c-Met overexpression contributes to the acquired apoptotic resistance of nonadherent ovarian cancer cells through a cross talk mediated by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2
    • Tang MK, Zhou HY, Yam JW, and Wong AS (2010). c-Met overexpression contributes to the acquired apoptotic resistance of nonadherent ovarian cancer cells through a cross talk mediated by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2. Neoplasia 12, 128-138.
    • (2010) Neoplasia , vol.12 , pp. 128-138
    • Tang, M.K.1    Zhou, H.Y.2    Yam, J.W.3    Wong, A.S.4
  • 42
    • 57049107462 scopus 로고    scopus 로고
    • Lack of oncogenic mutations in the c-met catalytic tyrosine kinase domain in acral lentiginous melanoma
    • Seidl H, Weger W, Wolf P, Kerl H, and Schaider H (2008). Lack of oncogenic mutations in the c-met catalytic tyrosine kinase domain in acral lentiginous melanoma. Int J Dermatol 47, 1327-1329.
    • (2008) Int J Dermatol , vol.47 , pp. 1327-1329
    • Seidl, H.1    Weger, W.2    Wolf, P.3    Kerl, H.4    Schaider, H.5
  • 43
    • 0035819040 scopus 로고    scopus 로고
    • Downregulation of E-cadherin and desmoglein 1 by autocrine hepatocyte growth factor during melanoma development
    • Li G, Schaider H, Satyamoorthy K, Hanakawa Y, Hashimoto K, and Herlyn M (2001). Downregulation of E-cadherin and desmoglein 1 by autocrine hepatocyte growth factor during melanoma development. Oncogene 20, 8125-8135.
    • (2001) Oncogene , vol.20 , pp. 8125-8135
    • Li, G.1    Schaider, H.2    Satyamoorthy, K.3    Hanakawa, Y.4    Hashimoto, K.5    Herlyn, M.6
  • 45
    • 34347252289 scopus 로고    scopus 로고
    • Up-regulation of MET expression by α-melanocyte-stimulating hormone and MITF allows hepatocyte growth factor to protect melanocytes and melanoma cells from apoptosis
    • Beuret L, Flori E, Denoyelle C, Bille K, Busca R, Picardo M, Bertolotto C, and Ballotti R (2007). Up-regulation of MET expression by α-melanocyte-stimulating hormone and MITF allows hepatocyte growth factor to protect melanocytes and melanoma cells from apoptosis. J Biol Chem 282, 14140-14147.
    • (2007) J Biol Chem , vol.282 , pp. 14140-14147
    • Beuret, L.1    Flori, E.2    Denoyelle, C.3    Bille, K.4    Busca, R.5    Picardo, M.6    Bertolotto, C.7    Ballotti, R.8
  • 46
    • 54349085882 scopus 로고    scopus 로고
    • Preclinical evaluation of dasatinib, a potent src kinase inhibitor, in melanoma cell lines
    • Eustace AJ, Crown J, Clynes M, and O'Donovan N (2008). Preclinical evaluation of dasatinib, a potent src kinase inhibitor, in melanoma cell lines. J Transl Med 6, 53.
    • (2008) J Transl Med , vol.6 , pp. 53
    • Eustace, A.J.1    Crown, J.2    Clynes, M.3    O'Donovan, N.4
  • 48
    • 0034537138 scopus 로고    scopus 로고
    • Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: Involvement of ras-dependent and-independent pathways
    • Genersch E, Hayess K, Neuenfeld Y, and Haller H (2000). Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of ras-dependent and-independent pathways. J Cell Sci 23(113 pt), 4319-4330.
    • (2000) J Cell Sci , vol.23 , Issue.113 PT , pp. 4319-4330
    • Genersch, E.1    Hayess, K.2    Neuenfeld, Y.3    Haller, H.4
  • 49
    • 4444240325 scopus 로고    scopus 로고
    • Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference
    • Sumimoto H, Miyagishi M, Miyoshi H, Yamagata S, Shimizu A, Taira K, and Kawakami Y (2004). Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference. Oncogene 23, 6031-6039.
    • (2004) Oncogene , vol.23 , pp. 6031-6039
    • Sumimoto, H.1    Miyagishi, M.2    Miyoshi, H.3    Yamagata, S.4    Shimizu, A.5    Taira, K.6    Kawakami, Y.7
  • 51
    • 84855466843 scopus 로고    scopus 로고
    • Regulation of SRC family kinases in human cancers
    • 2011, 865819
    • Sen B and Johnson FM (2011). Regulation of SRC family kinases in human cancers. J Signal Transduct 2011, 865819.
    • (2011) J Signal Transduct
    • Sen, B.1    Johnson, F.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.