Altered expression of miR-21, miR-125b, and miR-203 indicates a role for these microRNAs in oral lichen planus

Journal of Oral Pathology and Medicine

Volumn 41, Issue 1, 2012, Pages 90-95

  Danielsson, K ^a   Wahlin, Y B ^a   Gu, X ^a   Boldrup, L ^a   Nylander, K ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

MiR 125b; MiR 203; MiR 21; Oral lichen planus

Indexed keywords

MICRORNA; MICRORNA 125B; MICRORNA 203; MICRORNA 21; PROTEIN P53; PROTEIN P63; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LASER MICRODISSECTION; LICHEN PLANUS; MALE; MOUTH INFLAMMATION; MOUTH LICHEN PLANUS; ORAL BIOPSY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA EXTRACTION;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS REGULATORY PROTEINS; BIOPSY; CASE-CONTROL STUDIES; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LICHEN PLANUS, ORAL; MALE; MICRORNAS; MIDDLE AGED; MOUTH MUCOSA; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84855459831     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2011.01084.x     Document Type: Article

References (54)

1. Axell T, Rundquist L. Oral lichen planus - a demographic study. Community Dent Oral Epidemiol 1987; 15: 52-6.
2. Eisen D. The clinical features, malignant potential, and systemic associations of oral lichen planus: a study of 723 patients. J Am Acad Dermatol 2002; 46: 207-14.
3. Roopashree MR, Gondhalekar RV, Shashikanth MC, et al. Pathogenesis of oral lichen planus - a review. J Oral Pathol Med 2010; 39: 729-34.
4. Sugerman PB, Savage NW, Walsh LJ, et al. The pathogenesis of oral lichen planus. Crit Rev Oral Biol Med 2002; 13: 350-65.
5. Ebrahimi M, Wahlin YB, Coates PJ, et al. Detection of antibodies against p63 and p73 isoforms in sera from patients diagnosed with oral lichen planus. J Oral Pathol Med 2007; 36: 93-8.
6. Lukac J, Brozovic S, Vucicevic-Boras V, et al. Serum autoantibodies to desmogleins 1 and 3 in patients with oral lichen planus. Croat Med J 2006; 47: 53-8.
7. Pindborg JJ, Reichart PA, Smith CJ, et al. Histological typing of cancer and precancer of the oral mucosa. In: World Health Organization international histological classification of tumours. Berlin: Springer, 1997; 29-30.
8. Ebrahimi M, Wahlin YB, Coates PJ, et al. Decreased expression of p63 in oral lichen planus and graft-vs.-host disease associated with oral inflammation. J Oral Pathol Med 2006; 35: 46-50.
9. Ebrahimi M, Boldrup L, Coates PJ, et al. Expression of novel p53 isoforms in oral lichen planus. Oral Oncol 2008; 44: 156-61.
10. Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112: 1776-84.
11. Thiery JP. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 2003; 15: 740-6.
12. Pardali K, Moustakas A. Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer. Biochim Biophys Acta 2007; 1775: 21-62.
13. Lu SL, Reh D, Li AG, et al. Overexpression of transforming growth factor beta1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation. Cancer Res 2004; 64: 4405-10.
14. Danielsson K, Wahlin YB, Coates PJ, et al. Increased expression of Smad proteins, and in particular Smad3, in oral lichen planus compared to normal oral mucosa. J Oral Pathol Med 2010; 39: 639-44.
15. Zhao Y, Srivastava D. A developmental view of microRNA function. Trends Biochem Sci 2007; 32: 189-97.
16. Erson AE, Petty EM. MicroRNAs in development and disease. Clin Genet 2008; 74: 296-306.
17. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
18. He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004; 5: 522-31.
19. Rajewsky N. microRNA target predictions in animals. Nat Genet 2006; 38(Suppl): S8-13.
20. Krek A, Grun D, Poy MN, et al. Combinatorial microRNA target predictions. Nat Genet 2005; 37: 495-500.
21. Rentoft M, Fahlen J, Coates PJ, et al. miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples. Int J Oncol 2011; 38: 61-9.
22. Chang SS, Jiang WW, Smith I, et al. MicroRNA alterations in head and neck squamous cell carcinoma. Int J Cancer 2008; 123: 2791-7.
23. Urbich C, Kuehbacher A, Dimmeler S. Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res 2008; 79: 581-8.
24. Sonkoly E, Wei T, Janson PC, et al. MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS ONE 2007; 2: e610.
25. Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006; 103: 2257-61.
26. Frankel LB, Christoffersen NR, Jacobsen A, et al. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 2008; 283: 1026-33.
27. Papagiannakopoulos T, Shapiro A, Kosik KS. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res 2008; 68: 8164-72.
28. Krichevsky AM, Gabriely G. miR-21: a small multi-faceted RNA. J Cell Mol Med 2009; 13: 39-53.
29. Le MT, Teh C, Shyh-Chang N, et al. MicroRNA-125b is a novel negative regulator of p53. Genes Dev 2009; 23: 862-76.
30. Tili E, Michaille JJ, Cimino A, et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol 2007; 179: 5082-9.
31. Sethi G, Sung B, Aggarwal BB. TNF: a master switch for inflammation to cancer. Front Biosci 2008; 13: 5094-107.
32. Yamamoto T, Osaki T. Characteristic cytokines generated by keratinocytes and mononuclear infiltrates in oral lichen planus. J Invest Dermatol 1995; 104: 784-8.
33. Hui AB, Lenarduzzi M, Krushel T, et al. Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas. Clin Cancer Res 2010; 16: 1129-39.
34. Yi R, Poy MN, Stoffel M, et al. A skin microRNA promotes differentiation by repressing 'stemness'. Nature 2008; 452: 225-9.
35. Lena AM, Shalom-Feuerstein R, Rivetti Di Val Cervo P, et al. miR-203 represses 'stemness' by repressing DeltaNp63. Cell Death Differ 2008; 15: 1187-95.
36. Nylander E, Ebrahimi M, Wahlin Y, et al. Changes in miRNA expression in sera and correlation to duration of disease in patients with multifocal mucosal lichen planus. J Oral Pathol Med 2011; doi: 10.1111/j.1600-0714.2011.01063.x. [Epub ahead of print].
37. van der Meij EH, van der Waal I. Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications. J Oral Pathol Med 2003; 32: 507-12.
38. Rentoft M, Hultin S, Coates P, et al. TUBA6 (tubulin alpha-6 chain) is a stably expressed reference gene in archival samples of normal oral tissue and oral squamous cell carcinoma. Exp Ther Med 2010; 3: 419-23.
39. Cervigne NK, Reis PP, Machado J, et al. Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma. Hum Mol Genet 2009; 18: 4818-29.
40. Dekker NP, Lozada-Nur F, Lagenaur LA, et al. Apoptosis-associated markers in oral lichen planus. J Oral Pathol Med 1997; 26: 170-5.
41. Schifter M, Jones AM, Walker DM. Epithelial p53 gene expression and mutational analysis, combined with growth fraction assessment, in oral lichen planus. J Oral Pathol Med 1998; 27: 318-24.
42. Safadi RA, Al Jaber SZ, Hammad HM, et al. Oral lichen planus shows higher expressions of tumor suppressor gene products of p53 and p21 compared to oral mucositis. An immunohistochemical study. Arch Oral Biol 2010; 55: 454-61.
43. Hirota M, Ito T, Okudela K, et al. Cell proliferation activity and the expression of cell cycle regulatory proteins in oral lichen planus. J Oral Pathol Med 2002; 31: 204-12.
44. Ogmundsdottir HM, Hilmarsdottir H, Astvaldsdottir A, et al. Oral lichen planus has a high rate of TP53 mutations. A study of oral mucosa in icelanD. Eur J Oral Sci 2002; 110: 192-8.
45. Gonzalez-Moles MA, Bascones-Ilundain C, Gil Montoya JA, et al. Cell cycle regulating mechanisms in oral lichen planus: molecular bases in epithelium predisposed to malignant transformation. Arch Oral Biol 2006; 51: 1093-103.
46. Montebugnoli L, Farnedi A, Marchetti C, et al. High proliferative activity and chromosomal instability in oral lichen planus. Int J Oral Maxillofac Surg 2006; 35: 1140-4.
47. Prives C, HalL PA. The p53 pathway. J Pathol 1999; 187: 112-26.
48. Gu X, Lundqvist EN, Coates PJ, et al. Dysregulation of TAp63 mRNA and protein levels in psoriasis. J Invest Dermatol 2006; 126: 137-41.
49. Schetter AJ, Heegaard NH, Harris CC. Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways. Carcinogenesis 2010; 31: 37-49.
50. Davis BN, Hilyard AC, Lagna G, et al. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008; 454: 56-61.
51. Qian B, Katsaros D, Lu L, et al. High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1. Breast Cancer Res Treat 2009; 117: 131-40.
52. Henson BJ, Bhattacharjee S, O'Dee DM, et al. Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy. Genes Chromosom Cancer 2009; 48: 569-82.
53. Wei T, Orfanidis K, Xu N, et al. The expression of microRNA-203 during human skin morphogenesis. Exp Dermatol 2010; 19: 854-6.
54. TaniguchI Y, Nagao T, Maeda H, et al. Epithelial cell proliferation in oral lichen planus. Cell Prolif 2002; 35(Suppl 1): 103-9.