Acidic mammalian chitinase is not a critical target for allergic airway disease

American Journal of Respiratory Cell and Molecular Biology

Volumn 46, Issue 1, 2012, Pages 71-79

  Fitz, Lori J ^a   DeClercq, Charlene ^a   Brooks, Jonathan ^a   Kuang, Wen ^a,b   Bates, Brian ^a   Demers, Delia ^a   Winkler, Aaron ^a   Nocka, Karl ^a   Jiao, Aiping ^a   Greco, Rita M ^a   Mason, Lawrence E ^a   Fleming, Margaret ^a   Quazi, Amira ^a   Wright, Jill ^a   Goldman, Samuel ^a   Hubeau, Cedric ^a   Williams, Cara M M ^a  

^a PFIZER INC   (United States)

^b Hospira Global Pharma Research and Development   (United States)

Author keywords

Airway; Asthma; Chitinase; House dust mite; Ovalbumin

Indexed keywords

ACIDIC MAMMALIAN CHITINASE; ALLERGEN; ALLOSAMIDIN; CHITINASE; DEXAMETHASONE; HOUSE DUST ALLERGEN; INTERLEUKIN 13; OVALBUMIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCKROACH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INHIBITION; FEMALE; GENE OVEREXPRESSION; IMMUNOSTIMULATION; INFLAMMATORY INFILTRATE; LUNG INFILTRATE; LUNG LAVAGE; LYMPHOCYTE COUNT; MOUSE; MUTANT; NEUTROPHIL COUNT; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RESPIRATORY TRACT ALLERGY; SENSITIZATION; TH1 CELL; TH2 CELL; TRANSGENIC MOUSE; WILD TYPE;

ALLERGENS; ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CHITINASE; FEMALE; HUMANS; HYPERSENSITIVITY; INFLAMMATION; INTERLEUKIN-13; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEUTROPHILS; TH1 CELLS; TH2 CELLS;

BLATTARIA; MAMMALIA; MURINAE; MUS; PYROGLYPHIDAE;

EID: 84855406331     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0095OC     Document Type: Article

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