메뉴 건너뛰기




Volumn 7, Issue 1, 2012, Pages

Ctl responses of high functional avidity and broad variant cross-reactivity are associated with hiv control

(23)  Mothe, Beatriz a,b   Llano, Anuska a   Ibarrondo, Javier a,k   Zamarreño, Jennifer a   Schiaulini, Mattia a,b   Miranda, Cristina a   Ruiz Riol, Marta a   Berger, Christoph T c   Herrero, M José a   Palou, Eduard a   Plana, Montse d   Rolland, Morgane e,l   Khatri, Ashok c   Heckerman, David f   Pereyra, Florencia c   Walker, Bruce D c,g   Weiner, David h   Paredes, Roger a   Clotet, Bonaventura a   Felber, Barbara K i   more..


Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAG P24; GAG PROTEIN; HLA ANTIGEN CLASS 1; UNCLASSIFIED DRUG; T LYMPHOCYTE RECEPTOR;

EID: 84855396595     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029717     Document Type: Article
Times cited : (118)

References (42)
  • 1
    • 33846101731 scopus 로고    scopus 로고
    • CD8+ T-cell responses to different HIV proteins have discordant associations with viral load
    • Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, et al. (2007) CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat Med 13: 46-53.
    • (2007) Nat Med , vol.13 , pp. 46-53
    • Kiepiela, P.1    Ngumbela, K.2    Thobakgale, C.3    Ramduth, D.4    Honeyborne, I.5
  • 2
    • 1842614416 scopus 로고    scopus 로고
    • Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load
    • Masemola A, Mashishi T, Khoury G, Mohube P, Mokgotho P, et al. (2004) Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load. J Virol 78: 3233-3243.
    • (2004) J Virol , vol.78 , pp. 3233-3243
    • Masemola, A.1    Mashishi, T.2    Khoury, G.3    Mohube, P.4    Mokgotho, P.5
  • 3
    • 73349124525 scopus 로고    scopus 로고
    • Virological, immune and host genetics markers in the control of HIV infection
    • Mothe B, Ibarrondo J, Llano A, Brander C, (2009) Virological, immune and host genetics markers in the control of HIV infection. Dis Markers 27: 105-120.
    • (2009) Dis Markers , vol.27 , pp. 105-120
    • Mothe, B.1    Ibarrondo, J.2    Llano, A.3    Brander, C.4
  • 4
    • 33644755541 scopus 로고    scopus 로고
    • Relative dominance of Gag p24 specific CTL is associated with HIV control
    • Zuñiga R, Lucchetti A, Galvan P, Sanchez S, Sanchez C, et al. (2006) Relative dominance of Gag p24 specific CTL is associated with HIV control. J Virology 80: 3122-3125.
    • (2006) J Virology , vol.80 , pp. 3122-3125
    • Zuñiga, R.1    Lucchetti, A.2    Galvan, P.3    Sanchez, S.4    Sanchez, C.5
  • 5
    • 33847388794 scopus 로고    scopus 로고
    • Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression
    • Sacha JB, Chung C, Rakasz EG, Spencer SP, Jonas AK, et al. (2007) Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression. J Immunol 178: 2746-2754.
    • (2007) J Immunol , vol.178 , pp. 2746-2754
    • Sacha, J.B.1    Chung, C.2    Rakasz, E.G.3    Spencer, S.P.4    Jonas, A.K.5
  • 6
    • 43949094512 scopus 로고    scopus 로고
    • Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid
    • Schneidewind A, Brockman MA, Sidney J, Wang YE, Chen H, et al. (2008) Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid. J Virol 82: 5594-5605.
    • (2008) J Virol , vol.82 , pp. 5594-5605
    • Schneidewind, A.1    Brockman, M.A.2    Sidney, J.3    Wang, Y.E.4    Chen, H.5
  • 7
    • 80052198797 scopus 로고    scopus 로고
    • High-Functional-Avidity Cytotoxic T Lymphocyte Responses to HLA-B-Restricted Gag-Derived Epitopes Associated with Relative HIV Control
    • Berger CT, Frahm N, Price DA, Mothe B, Ghebremichael M, et al. (2011) High-Functional-Avidity Cytotoxic T Lymphocyte Responses to HLA-B-Restricted Gag-Derived Epitopes Associated with Relative HIV Control. J Virol 85: 9334-9345.
    • (2011) J Virol , vol.85 , pp. 9334-9345
    • Berger, C.T.1    Frahm, N.2    Price, D.A.3    Mothe, B.4    Ghebremichael, M.5
  • 8
    • 79961160736 scopus 로고    scopus 로고
    • Protective HIV-specific CD8(+) T cells evade T(reg) cell suppression
    • Elahi S, Dinges WL, Lejarcegui N, Laing KJ, Collier AC, et al. (2011) Protective HIV-specific CD8(+) T cells evade T(reg) cell suppression. Nat Med 17: 989-995.
    • (2011) Nat Med , vol.17 , pp. 989-995
    • Elahi, S.1    Dinges, W.L.2    Lejarcegui, N.3    Laing, K.J.4    Collier, A.C.5
  • 9
    • 33646472100 scopus 로고    scopus 로고
    • HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently
    • Turnbull EL, Lopes AR, Jones NA, Cornforth D, Newton P, et al. (2006) HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently. J Immunol 176: 6130-6146.
    • (2006) J Immunol , vol.176 , pp. 6130-6146
    • Turnbull, E.L.1    Lopes, A.R.2    Jones, N.A.3    Cornforth, D.4    Newton, P.5
  • 10
    • 0037377309 scopus 로고    scopus 로고
    • Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses
    • Draenert R, Altfeld M, Brander C, Basgoz N, Corcoran C, et al. (2003) Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses. J Immunol Methods 275: 19-29.
    • (2003) J Immunol Methods , vol.275 , pp. 19-29
    • Draenert, R.1    Altfeld, M.2    Brander, C.3    Basgoz, N.4    Corcoran, C.5
  • 11
    • 34247635041 scopus 로고    scopus 로고
    • Detection of HIV vaccine-induced cell-mediated immunity in HIV-seronegative clinical trial participants using an optimized and validated enzyme-linked immunospot assay
    • Dubey S, Clair J, Fu TM, Guan L, Long R, et al. (2007) Detection of HIV vaccine-induced cell-mediated immunity in HIV-seronegative clinical trial participants using an optimized and validated enzyme-linked immunospot assay. J Acquir Immune Defic Syndr 45: 20-27.
    • (2007) J Acquir Immune Defic Syndr , vol.45 , pp. 20-27
    • Dubey, S.1    Clair, J.2    Fu, T.M.3    Guan, L.4    Long, R.5
  • 12
    • 77950877551 scopus 로고    scopus 로고
    • Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype
    • Dinges WL, Richardt J, Friedrich D, Jalbert E, Liu Y, et al. (2010) Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype. J Virol 84: 4461-4468.
    • (2010) J Virol , vol.84 , pp. 4461-4468
    • Dinges, W.L.1    Richardt, J.2    Friedrich, D.3    Jalbert, E.4    Liu, Y.5
  • 14
    • 10744226946 scopus 로고    scopus 로고
    • Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities
    • Frahm N, Korber BT, Adams CM, Szinger JJ, Draenert R, et al. (2004) Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. J Virol 78: 2187-2200.
    • (2004) J Virol , vol.78 , pp. 2187-2200
    • Frahm, N.1    Korber, B.T.2    Adams, C.M.3    Szinger, J.J.4    Draenert, R.5
  • 15
    • 38449086859 scopus 로고    scopus 로고
    • Increased sequence diversity coverage improves detection of HIV-specific T cell responses
    • Frahm N, Kaufmann DE, Yusim K, Muldoon M, Kesmir C, et al. (2007) Increased sequence diversity coverage improves detection of HIV-specific T cell responses. J Immunol 179: 6638-6650.
    • (2007) J Immunol , vol.179 , pp. 6638-6650
    • Frahm, N.1    Kaufmann, D.E.2    Yusim, K.3    Muldoon, M.4    Kesmir, C.5
  • 17
    • 40149099742 scopus 로고    scopus 로고
    • Increased cytotoxic T-lymphocyte epitope variant cross-recognition and functional avidity are associated with hepatitis C virus clearance
    • Yerly D, Heckerman D, Allen TM, Chisholm JV 3rd, Faircloth K, et al. (2008) Increased cytotoxic T-lymphocyte epitope variant cross-recognition and functional avidity are associated with hepatitis C virus clearance. J Virol 82: 3147-3153.
    • (2008) J Virol , vol.82 , pp. 3147-3153
    • Yerly, D.1    Heckerman, D.2    Allen, T.M.3    Chisholm III, J.V.4    Faircloth, K.5
  • 19
    • 80052317836 scopus 로고    scopus 로고
    • Development and preclinical safety evaluation of a new therapeutic HIV-1 vaccine based on 18 T-cell minimal epitope peptides applying a novel cationic adjuvant CAF01
    • Fomsgaard A, Karlsson I, Gram G, Schou C, Tang S, et al. Development and preclinical safety evaluation of a new therapeutic HIV-1 vaccine based on 18 T-cell minimal epitope peptides applying a novel cationic adjuvant CAF01. Vaccine.
    • Vaccine
    • Fomsgaard, A.1    Karlsson, I.2    Gram, G.3    Schou, C.4    Tang, S.5
  • 20
    • 79958726847 scopus 로고    scopus 로고
    • Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the step study
    • Li F, Finnefrock AC, Dubey SA, Korber BT, Szinger J, et al. Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the step study. PLoS One 6: e20479.
    • PLoS One , vol.6
    • Li, F.1    Finnefrock, A.C.2    Dubey, S.A.3    Korber, B.T.4    Szinger, J.5
  • 21
    • 50949117244 scopus 로고    scopus 로고
    • Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection
    • Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, et al. (2008) Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. J Virol 82: 9216-9227.
    • (2008) J Virol , vol.82 , pp. 9216-9227
    • Brumme, Z.L.1    Brumme, C.J.2    Carlson, J.3    Streeck, H.4    John, M.5
  • 22
    • 0035862326 scopus 로고    scopus 로고
    • Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
    • Goulder PJ, Altfeld MA, Rosenberg ES, Nguyen T, Tang Y, et al. (2001) Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection. J Exp Med 193: 181-194.
    • (2001) J Exp Med , vol.193 , pp. 181-194
    • Goulder, P.J.1    Altfeld, M.A.2    Rosenberg, E.S.3    Nguyen, T.4    Tang, Y.5
  • 23
    • 0035913225 scopus 로고    scopus 로고
    • Evolution and transmission of stable CTL escape mutations in HIV infection
    • Goulder PJ, Brander C, Tang Y, Tremblay C, Colbert RA, et al. (2001) Evolution and transmission of stable CTL escape mutations in HIV infection. Nature 412: 334-338.
    • (2001) Nature , vol.412 , pp. 334-338
    • Goulder, P.J.1    Brander, C.2    Tang, Y.3    Tremblay, C.4    Colbert, R.A.5
  • 24
    • 84855361961 scopus 로고    scopus 로고
    • Epitope specific CD8+ T-cell responses predict spontaneous HIV virus replication
    • AIDS Vaccine Meeting. Cape Town, South Africa
    • Pereyra F, Heckerman D, Rothchild A, Block B, Baker B, et al. (2008) Epitope specific CD8+ T-cell responses predict spontaneous HIV virus replication. AIDS Vaccine Meeting. Cape Town, South Africa.
    • (2008)
    • Pereyra, F.1    Heckerman, D.2    Rothchild, A.3    Block, B.4    Baker, B.5
  • 25
    • 34548794906 scopus 로고    scopus 로고
    • Extensive HLA class I allele promiscuity among viral cytotoxic T lymphocyte (CTL) epitopes
    • Frahm N, Yusim K, Adams S, Sidney J, Hraber P, et al. (2007) Extensive HLA class I allele promiscuity among viral cytotoxic T lymphocyte (CTL) epitopes. Europ J Immunol 37: 2419-2433.
    • (2007) Europ J Immunol , vol.37 , pp. 2419-2433
    • Frahm, N.1    Yusim, K.2    Adams, S.3    Sidney, J.4    Hraber, P.5
  • 26
    • 79951945491 scopus 로고    scopus 로고
    • How to Optimally Define Optimal Cytotoxic T Lymphocyte Epitopes in HIV Infection?
    • In: B. Korber CB, Walker B, Koup R, Moore J, Haynes B, Meyers G, editors, Los Alamos, NM, USA, Los Alamos National Laboratory: Theoretical Biology and Biophysics
    • Llano A, Frahm N, Brander C, (2009) How to Optimally Define Optimal Cytotoxic T Lymphocyte Epitopes in HIV Infection? In: B. Korber CB, Walker B, Koup R, Moore J, Haynes B, Meyers G, editors. HIV Molecular immunology database Los Alamos, NM, USA Los Alamos National Laboratory: Theoretical Biology and Biophysics.
    • (2009) HIV Molecular Immunology Database
    • Llano, A.1    Frahm, N.2    Brander, C.3
  • 27
    • 33750822983 scopus 로고    scopus 로고
    • Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection
    • Horton H, Frank I, Baydo R, Jalbert E, Penn J, et al. (2006) Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection. J Immunol 177: 7406-7415.
    • (2006) J Immunol , vol.177 , pp. 7406-7415
    • Horton, H.1    Frank, I.2    Baydo, R.3    Jalbert, E.4    Penn, J.5
  • 28
    • 34247109635 scopus 로고    scopus 로고
    • Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection
    • Lichterfeld M, Yu XG, Mui SK, Williams KL, Trocha A, et al. (2007) Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection. J Virol 81: 4199-4214.
    • (2007) J Virol , vol.81 , pp. 4199-4214
    • Lichterfeld, M.1    Yu, X.G.2    Mui, S.K.3    Williams, K.L.4    Trocha, A.5
  • 29
    • 2442500442 scopus 로고    scopus 로고
    • The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration
    • Betts MR, Price DA, Brenchley JM, Lore K, Guenaga FJ, et al. (2004) The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration. J Immunol 172: 6407-6417.
    • (2004) J Immunol , vol.172 , pp. 6407-6417
    • Betts, M.R.1    Price, D.A.2    Brenchley, J.M.3    Lore, K.4    Guenaga, F.J.5
  • 30
    • 0029965055 scopus 로고    scopus 로고
    • Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
    • Alexander-Miller MA, Leggatt GR, Berzofsky JA, (1996) Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc Natl Acad Sci U S A 93: 4102-4107.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 4102-4107
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Berzofsky, J.A.3
  • 31
    • 34948906159 scopus 로고    scopus 로고
    • Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
    • Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med 204: 2473-2485.
    • (2007) J Exp Med , vol.204 , pp. 2473-2485
    • Almeida, J.R.1    Price, D.A.2    Papagno, L.3    Arkoub, Z.A.4    Sauce, D.5
  • 32
    • 67650581553 scopus 로고    scopus 로고
    • Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity
    • Almeida JR, Sauce D, Price DA, Papagno L, Shin SY, et al. (2009) Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood 113: 6351-6360.
    • (2009) Blood , vol.113 , pp. 6351-6360
    • Almeida, J.R.1    Sauce, D.2    Price, D.A.3    Papagno, L.4    Shin, S.Y.5
  • 33
    • 78349304870 scopus 로고    scopus 로고
    • Fine-tuning of T-cell receptor avidity to increase HIV epitope variant recognition by cytotoxic T lymphocytes
    • Bennett MS, Joseph A, Ng HL, Goldstein H, Yang OO, (2010) Fine-tuning of T-cell receptor avidity to increase HIV epitope variant recognition by cytotoxic T lymphocytes. AIDS.
    • (2010) AIDS
    • Bennett, M.S.1    Joseph, A.2    Ng, H.L.3    Goldstein, H.4    Yang, O.O.5
  • 34
    • 33646019589 scopus 로고    scopus 로고
    • Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses
    • Bihl F, Frahm N, Di Giammarino L, Sidney J, John M, et al. (2006) Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses. J Immunol 176: 4094-4101.
    • (2006) J Immunol , vol.176 , pp. 4094-4101
    • Bihl, F.1    Frahm, N.2    Di Giammarino, L.3    Sidney, J.4    John, M.5
  • 35
    • 2242419092 scopus 로고    scopus 로고
    • Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense
    • Messaoudi I, Guevara Patino JA, Dyall R, LeMaoult J, N-Z J, (2002) Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense. Science 298: 1797-1780.
    • (2002) Science , vol.298 , pp. 1780-1797
    • Messaoudi, I.1    Guevara Patino, J.A.2    Dyall, R.3    LeMaoult, J.N.-Z.J.4
  • 36
    • 0034130519 scopus 로고    scopus 로고
    • In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity
    • Sedlik C, Dadaglio G, Saron MF, Deriaud E, Rojas M, et al. (2000) In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity. J Virol 74: 5769-5775.
    • (2000) J Virol , vol.74 , pp. 5769-5775
    • Sedlik, C.1    Dadaglio, G.2    Saron, M.F.3    Deriaud, E.4    Rojas, M.5
  • 38
    • 27944505610 scopus 로고    scopus 로고
    • Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses
    • Price DA, Brenchley JM, Ruff LE, Betts MR, Hill BJ, et al. (2005) Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. J Exp Med 202: 1349-1361.
    • (2005) J Exp Med , vol.202 , pp. 1349-1361
    • Price, D.A.1    Brenchley, J.M.2    Ruff, L.E.3    Betts, M.R.4    Hill, B.J.5
  • 39
    • 0033561632 scopus 로고    scopus 로고
    • Persistent HIV-1 specific CTL clonal expansion despite high viral burden post in-utero HIV-1 infection
    • Brander C, Goulder PJR, Luzuriaga K, Yang OO, Hartman K, et al. (1999) Persistent HIV-1 specific CTL clonal expansion despite high viral burden post in-utero HIV-1 infection. J Immunol 162: 4796-4800.
    • (1999) J Immunol , vol.162 , pp. 4796-4800
    • Brander, C.1    Goulder, P.J.R.2    Luzuriaga, K.3    Yang, O.O.4    Hartman, K.5
  • 40
    • 0034661671 scopus 로고    scopus 로고
    • Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors
    • Gea-Banacloche JC, Migueles SA, Martino L, Shupert WL, McNeil AC, et al. (2000) Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors. J Immunol 165: 1082-1092.
    • (2000) J Immunol , vol.165 , pp. 1082-1092
    • Gea-Banacloche, J.C.1    Migueles, S.A.2    Martino, L.3    Shupert, W.L.4    McNeil, A.C.5
  • 41
    • 0035054379 scopus 로고    scopus 로고
    • Direct ex vivo analysis reveals distinct phenotypic patterns of HIV- specific CD8(+) T lymphocyte activation in response to therapeutic manipulation of virus load
    • Oxenius A, Gunthard HF, Hirschel B, Fidler S, Weber JN, et al. (2001) Direct ex vivo analysis reveals distinct phenotypic patterns of HIV- specific CD8(+) T lymphocyte activation in response to therapeutic manipulation of virus load. Eur J Immunol 31: 1115-1121.
    • (2001) Eur J Immunol , vol.31 , pp. 1115-1121
    • Oxenius, A.1    Gunthard, H.F.2    Hirschel, B.3    Fidler, S.4    Weber, J.N.5
  • 42
    • 33645806969 scopus 로고    scopus 로고
    • Large HIV-specific CD8 cytotoxic T-lymphocyte (CTL) clones reduce their overall size but maintain high frequencies of memory CTL following highly active antiretroviral therapy
    • Weekes MP, Wills MR, Sissons JG, Carmichael AJ, (2006) Large HIV-specific CD8 cytotoxic T-lymphocyte (CTL) clones reduce their overall size but maintain high frequencies of memory CTL following highly active antiretroviral therapy. Immunology 118: 25-38.
    • (2006) Immunology , vol.118 , pp. 25-38
    • Weekes, M.P.1    Wills, M.R.2    Sissons, J.G.3    Carmichael, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.