-
1
-
-
33846101731
-
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load
-
Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, et al. (2007) CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat Med 13: 46-53.
-
(2007)
Nat Med
, vol.13
, pp. 46-53
-
-
Kiepiela, P.1
Ngumbela, K.2
Thobakgale, C.3
Ramduth, D.4
Honeyborne, I.5
-
2
-
-
1842614416
-
Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load
-
Masemola A, Mashishi T, Khoury G, Mohube P, Mokgotho P, et al. (2004) Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load. J Virol 78: 3233-3243.
-
(2004)
J Virol
, vol.78
, pp. 3233-3243
-
-
Masemola, A.1
Mashishi, T.2
Khoury, G.3
Mohube, P.4
Mokgotho, P.5
-
3
-
-
73349124525
-
Virological, immune and host genetics markers in the control of HIV infection
-
Mothe B, Ibarrondo J, Llano A, Brander C, (2009) Virological, immune and host genetics markers in the control of HIV infection. Dis Markers 27: 105-120.
-
(2009)
Dis Markers
, vol.27
, pp. 105-120
-
-
Mothe, B.1
Ibarrondo, J.2
Llano, A.3
Brander, C.4
-
4
-
-
33644755541
-
Relative dominance of Gag p24 specific CTL is associated with HIV control
-
Zuñiga R, Lucchetti A, Galvan P, Sanchez S, Sanchez C, et al. (2006) Relative dominance of Gag p24 specific CTL is associated with HIV control. J Virology 80: 3122-3125.
-
(2006)
J Virology
, vol.80
, pp. 3122-3125
-
-
Zuñiga, R.1
Lucchetti, A.2
Galvan, P.3
Sanchez, S.4
Sanchez, C.5
-
5
-
-
33847388794
-
Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression
-
Sacha JB, Chung C, Rakasz EG, Spencer SP, Jonas AK, et al. (2007) Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression. J Immunol 178: 2746-2754.
-
(2007)
J Immunol
, vol.178
, pp. 2746-2754
-
-
Sacha, J.B.1
Chung, C.2
Rakasz, E.G.3
Spencer, S.P.4
Jonas, A.K.5
-
6
-
-
43949094512
-
Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid
-
Schneidewind A, Brockman MA, Sidney J, Wang YE, Chen H, et al. (2008) Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid. J Virol 82: 5594-5605.
-
(2008)
J Virol
, vol.82
, pp. 5594-5605
-
-
Schneidewind, A.1
Brockman, M.A.2
Sidney, J.3
Wang, Y.E.4
Chen, H.5
-
7
-
-
80052198797
-
High-Functional-Avidity Cytotoxic T Lymphocyte Responses to HLA-B-Restricted Gag-Derived Epitopes Associated with Relative HIV Control
-
Berger CT, Frahm N, Price DA, Mothe B, Ghebremichael M, et al. (2011) High-Functional-Avidity Cytotoxic T Lymphocyte Responses to HLA-B-Restricted Gag-Derived Epitopes Associated with Relative HIV Control. J Virol 85: 9334-9345.
-
(2011)
J Virol
, vol.85
, pp. 9334-9345
-
-
Berger, C.T.1
Frahm, N.2
Price, D.A.3
Mothe, B.4
Ghebremichael, M.5
-
8
-
-
79961160736
-
Protective HIV-specific CD8(+) T cells evade T(reg) cell suppression
-
Elahi S, Dinges WL, Lejarcegui N, Laing KJ, Collier AC, et al. (2011) Protective HIV-specific CD8(+) T cells evade T(reg) cell suppression. Nat Med 17: 989-995.
-
(2011)
Nat Med
, vol.17
, pp. 989-995
-
-
Elahi, S.1
Dinges, W.L.2
Lejarcegui, N.3
Laing, K.J.4
Collier, A.C.5
-
9
-
-
33646472100
-
HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently
-
Turnbull EL, Lopes AR, Jones NA, Cornforth D, Newton P, et al. (2006) HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficiently. J Immunol 176: 6130-6146.
-
(2006)
J Immunol
, vol.176
, pp. 6130-6146
-
-
Turnbull, E.L.1
Lopes, A.R.2
Jones, N.A.3
Cornforth, D.4
Newton, P.5
-
10
-
-
0037377309
-
Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses
-
Draenert R, Altfeld M, Brander C, Basgoz N, Corcoran C, et al. (2003) Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses. J Immunol Methods 275: 19-29.
-
(2003)
J Immunol Methods
, vol.275
, pp. 19-29
-
-
Draenert, R.1
Altfeld, M.2
Brander, C.3
Basgoz, N.4
Corcoran, C.5
-
11
-
-
34247635041
-
Detection of HIV vaccine-induced cell-mediated immunity in HIV-seronegative clinical trial participants using an optimized and validated enzyme-linked immunospot assay
-
Dubey S, Clair J, Fu TM, Guan L, Long R, et al. (2007) Detection of HIV vaccine-induced cell-mediated immunity in HIV-seronegative clinical trial participants using an optimized and validated enzyme-linked immunospot assay. J Acquir Immune Defic Syndr 45: 20-27.
-
(2007)
J Acquir Immune Defic Syndr
, vol.45
, pp. 20-27
-
-
Dubey, S.1
Clair, J.2
Fu, T.M.3
Guan, L.4
Long, R.5
-
12
-
-
77950877551
-
Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype
-
Dinges WL, Richardt J, Friedrich D, Jalbert E, Liu Y, et al. (2010) Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype. J Virol 84: 4461-4468.
-
(2010)
J Virol
, vol.84
, pp. 4461-4468
-
-
Dinges, W.L.1
Richardt, J.2
Friedrich, D.3
Jalbert, E.4
Liu, Y.5
-
14
-
-
10744226946
-
Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities
-
Frahm N, Korber BT, Adams CM, Szinger JJ, Draenert R, et al. (2004) Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. J Virol 78: 2187-2200.
-
(2004)
J Virol
, vol.78
, pp. 2187-2200
-
-
Frahm, N.1
Korber, B.T.2
Adams, C.M.3
Szinger, J.J.4
Draenert, R.5
-
15
-
-
38449086859
-
Increased sequence diversity coverage improves detection of HIV-specific T cell responses
-
Frahm N, Kaufmann DE, Yusim K, Muldoon M, Kesmir C, et al. (2007) Increased sequence diversity coverage improves detection of HIV-specific T cell responses. J Immunol 179: 6638-6650.
-
(2007)
J Immunol
, vol.179
, pp. 6638-6650
-
-
Frahm, N.1
Kaufmann, D.E.2
Yusim, K.3
Muldoon, M.4
Kesmir, C.5
-
16
-
-
34047173102
-
Avidity of CD8 T cells sharpens immunodominance
-
Dzutsev AH, Belyakov IM, Isakov DV, Margulies DH, Berzofsky JA, (2007) Avidity of CD8 T cells sharpens immunodominance. Int Immunol 19: 497-507.
-
(2007)
Int Immunol
, vol.19
, pp. 497-507
-
-
Dzutsev, A.H.1
Belyakov, I.M.2
Isakov, D.V.3
Margulies, D.H.4
Berzofsky, J.A.5
-
17
-
-
40149099742
-
Increased cytotoxic T-lymphocyte epitope variant cross-recognition and functional avidity are associated with hepatitis C virus clearance
-
Yerly D, Heckerman D, Allen TM, Chisholm JV 3rd, Faircloth K, et al. (2008) Increased cytotoxic T-lymphocyte epitope variant cross-recognition and functional avidity are associated with hepatitis C virus clearance. J Virol 82: 3147-3153.
-
(2008)
J Virol
, vol.82
, pp. 3147-3153
-
-
Yerly, D.1
Heckerman, D.2
Allen, T.M.3
Chisholm III, J.V.4
Faircloth, K.5
-
19
-
-
80052317836
-
Development and preclinical safety evaluation of a new therapeutic HIV-1 vaccine based on 18 T-cell minimal epitope peptides applying a novel cationic adjuvant CAF01
-
Fomsgaard A, Karlsson I, Gram G, Schou C, Tang S, et al. Development and preclinical safety evaluation of a new therapeutic HIV-1 vaccine based on 18 T-cell minimal epitope peptides applying a novel cationic adjuvant CAF01. Vaccine.
-
Vaccine
-
-
Fomsgaard, A.1
Karlsson, I.2
Gram, G.3
Schou, C.4
Tang, S.5
-
20
-
-
79958726847
-
Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the step study
-
Li F, Finnefrock AC, Dubey SA, Korber BT, Szinger J, et al. Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the step study. PLoS One 6: e20479.
-
PLoS One
, vol.6
-
-
Li, F.1
Finnefrock, A.C.2
Dubey, S.A.3
Korber, B.T.4
Szinger, J.5
-
21
-
-
50949117244
-
Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection
-
Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, et al. (2008) Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection. J Virol 82: 9216-9227.
-
(2008)
J Virol
, vol.82
, pp. 9216-9227
-
-
Brumme, Z.L.1
Brumme, C.J.2
Carlson, J.3
Streeck, H.4
John, M.5
-
22
-
-
0035862326
-
Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection
-
Goulder PJ, Altfeld MA, Rosenberg ES, Nguyen T, Tang Y, et al. (2001) Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection. J Exp Med 193: 181-194.
-
(2001)
J Exp Med
, vol.193
, pp. 181-194
-
-
Goulder, P.J.1
Altfeld, M.A.2
Rosenberg, E.S.3
Nguyen, T.4
Tang, Y.5
-
23
-
-
0035913225
-
Evolution and transmission of stable CTL escape mutations in HIV infection
-
Goulder PJ, Brander C, Tang Y, Tremblay C, Colbert RA, et al. (2001) Evolution and transmission of stable CTL escape mutations in HIV infection. Nature 412: 334-338.
-
(2001)
Nature
, vol.412
, pp. 334-338
-
-
Goulder, P.J.1
Brander, C.2
Tang, Y.3
Tremblay, C.4
Colbert, R.A.5
-
24
-
-
84855361961
-
Epitope specific CD8+ T-cell responses predict spontaneous HIV virus replication
-
AIDS Vaccine Meeting. Cape Town, South Africa
-
Pereyra F, Heckerman D, Rothchild A, Block B, Baker B, et al. (2008) Epitope specific CD8+ T-cell responses predict spontaneous HIV virus replication. AIDS Vaccine Meeting. Cape Town, South Africa.
-
(2008)
-
-
Pereyra, F.1
Heckerman, D.2
Rothchild, A.3
Block, B.4
Baker, B.5
-
25
-
-
34548794906
-
Extensive HLA class I allele promiscuity among viral cytotoxic T lymphocyte (CTL) epitopes
-
Frahm N, Yusim K, Adams S, Sidney J, Hraber P, et al. (2007) Extensive HLA class I allele promiscuity among viral cytotoxic T lymphocyte (CTL) epitopes. Europ J Immunol 37: 2419-2433.
-
(2007)
Europ J Immunol
, vol.37
, pp. 2419-2433
-
-
Frahm, N.1
Yusim, K.2
Adams, S.3
Sidney, J.4
Hraber, P.5
-
26
-
-
79951945491
-
How to Optimally Define Optimal Cytotoxic T Lymphocyte Epitopes in HIV Infection?
-
In: B. Korber CB, Walker B, Koup R, Moore J, Haynes B, Meyers G, editors, Los Alamos, NM, USA, Los Alamos National Laboratory: Theoretical Biology and Biophysics
-
Llano A, Frahm N, Brander C, (2009) How to Optimally Define Optimal Cytotoxic T Lymphocyte Epitopes in HIV Infection? In: B. Korber CB, Walker B, Koup R, Moore J, Haynes B, Meyers G, editors. HIV Molecular immunology database Los Alamos, NM, USA Los Alamos National Laboratory: Theoretical Biology and Biophysics.
-
(2009)
HIV Molecular Immunology Database
-
-
Llano, A.1
Frahm, N.2
Brander, C.3
-
27
-
-
33750822983
-
Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection
-
Horton H, Frank I, Baydo R, Jalbert E, Penn J, et al. (2006) Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection. J Immunol 177: 7406-7415.
-
(2006)
J Immunol
, vol.177
, pp. 7406-7415
-
-
Horton, H.1
Frank, I.2
Baydo, R.3
Jalbert, E.4
Penn, J.5
-
28
-
-
34247109635
-
Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection
-
Lichterfeld M, Yu XG, Mui SK, Williams KL, Trocha A, et al. (2007) Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection. J Virol 81: 4199-4214.
-
(2007)
J Virol
, vol.81
, pp. 4199-4214
-
-
Lichterfeld, M.1
Yu, X.G.2
Mui, S.K.3
Williams, K.L.4
Trocha, A.5
-
29
-
-
2442500442
-
The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration
-
Betts MR, Price DA, Brenchley JM, Lore K, Guenaga FJ, et al. (2004) The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration. J Immunol 172: 6407-6417.
-
(2004)
J Immunol
, vol.172
, pp. 6407-6417
-
-
Betts, M.R.1
Price, D.A.2
Brenchley, J.M.3
Lore, K.4
Guenaga, F.J.5
-
30
-
-
0029965055
-
Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
-
Alexander-Miller MA, Leggatt GR, Berzofsky JA, (1996) Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc Natl Acad Sci U S A 93: 4102-4107.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 4102-4107
-
-
Alexander-Miller, M.A.1
Leggatt, G.R.2
Berzofsky, J.A.3
-
31
-
-
34948906159
-
Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
-
Almeida JR, Price DA, Papagno L, Arkoub ZA, Sauce D, et al. (2007) Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J Exp Med 204: 2473-2485.
-
(2007)
J Exp Med
, vol.204
, pp. 2473-2485
-
-
Almeida, J.R.1
Price, D.A.2
Papagno, L.3
Arkoub, Z.A.4
Sauce, D.5
-
32
-
-
67650581553
-
Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity
-
Almeida JR, Sauce D, Price DA, Papagno L, Shin SY, et al. (2009) Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood 113: 6351-6360.
-
(2009)
Blood
, vol.113
, pp. 6351-6360
-
-
Almeida, J.R.1
Sauce, D.2
Price, D.A.3
Papagno, L.4
Shin, S.Y.5
-
33
-
-
78349304870
-
Fine-tuning of T-cell receptor avidity to increase HIV epitope variant recognition by cytotoxic T lymphocytes
-
Bennett MS, Joseph A, Ng HL, Goldstein H, Yang OO, (2010) Fine-tuning of T-cell receptor avidity to increase HIV epitope variant recognition by cytotoxic T lymphocytes. AIDS.
-
(2010)
AIDS
-
-
Bennett, M.S.1
Joseph, A.2
Ng, H.L.3
Goldstein, H.4
Yang, O.O.5
-
34
-
-
33646019589
-
Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses
-
Bihl F, Frahm N, Di Giammarino L, Sidney J, John M, et al. (2006) Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses. J Immunol 176: 4094-4101.
-
(2006)
J Immunol
, vol.176
, pp. 4094-4101
-
-
Bihl, F.1
Frahm, N.2
Di Giammarino, L.3
Sidney, J.4
John, M.5
-
35
-
-
2242419092
-
Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense
-
Messaoudi I, Guevara Patino JA, Dyall R, LeMaoult J, N-Z J, (2002) Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense. Science 298: 1797-1780.
-
(2002)
Science
, vol.298
, pp. 1780-1797
-
-
Messaoudi, I.1
Guevara Patino, J.A.2
Dyall, R.3
LeMaoult, J.N.-Z.J.4
-
36
-
-
0034130519
-
In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity
-
Sedlik C, Dadaglio G, Saron MF, Deriaud E, Rojas M, et al. (2000) In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity. J Virol 74: 5769-5775.
-
(2000)
J Virol
, vol.74
, pp. 5769-5775
-
-
Sedlik, C.1
Dadaglio, G.2
Saron, M.F.3
Deriaud, E.4
Rojas, M.5
-
37
-
-
0041751271
-
Molecular mechanisms and biological significance of CTL avidity
-
Snyder JT, Alexander-Miller MA, Berzofskyl JA, Belyakov IM, (2003) Molecular mechanisms and biological significance of CTL avidity. Curr HIV Res 1: 287-294.
-
(2003)
Curr HIV Res
, vol.1
, pp. 287-294
-
-
Snyder, J.T.1
Alexander-Miller, M.A.2
Berzofskyl, J.A.3
Belyakov, I.M.4
-
38
-
-
27944505610
-
Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses
-
Price DA, Brenchley JM, Ruff LE, Betts MR, Hill BJ, et al. (2005) Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. J Exp Med 202: 1349-1361.
-
(2005)
J Exp Med
, vol.202
, pp. 1349-1361
-
-
Price, D.A.1
Brenchley, J.M.2
Ruff, L.E.3
Betts, M.R.4
Hill, B.J.5
-
39
-
-
0033561632
-
Persistent HIV-1 specific CTL clonal expansion despite high viral burden post in-utero HIV-1 infection
-
Brander C, Goulder PJR, Luzuriaga K, Yang OO, Hartman K, et al. (1999) Persistent HIV-1 specific CTL clonal expansion despite high viral burden post in-utero HIV-1 infection. J Immunol 162: 4796-4800.
-
(1999)
J Immunol
, vol.162
, pp. 4796-4800
-
-
Brander, C.1
Goulder, P.J.R.2
Luzuriaga, K.3
Yang, O.O.4
Hartman, K.5
-
40
-
-
0034661671
-
Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors
-
Gea-Banacloche JC, Migueles SA, Martino L, Shupert WL, McNeil AC, et al. (2000) Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors. J Immunol 165: 1082-1092.
-
(2000)
J Immunol
, vol.165
, pp. 1082-1092
-
-
Gea-Banacloche, J.C.1
Migueles, S.A.2
Martino, L.3
Shupert, W.L.4
McNeil, A.C.5
-
41
-
-
0035054379
-
Direct ex vivo analysis reveals distinct phenotypic patterns of HIV- specific CD8(+) T lymphocyte activation in response to therapeutic manipulation of virus load
-
Oxenius A, Gunthard HF, Hirschel B, Fidler S, Weber JN, et al. (2001) Direct ex vivo analysis reveals distinct phenotypic patterns of HIV- specific CD8(+) T lymphocyte activation in response to therapeutic manipulation of virus load. Eur J Immunol 31: 1115-1121.
-
(2001)
Eur J Immunol
, vol.31
, pp. 1115-1121
-
-
Oxenius, A.1
Gunthard, H.F.2
Hirschel, B.3
Fidler, S.4
Weber, J.N.5
-
42
-
-
33645806969
-
Large HIV-specific CD8 cytotoxic T-lymphocyte (CTL) clones reduce their overall size but maintain high frequencies of memory CTL following highly active antiretroviral therapy
-
Weekes MP, Wills MR, Sissons JG, Carmichael AJ, (2006) Large HIV-specific CD8 cytotoxic T-lymphocyte (CTL) clones reduce their overall size but maintain high frequencies of memory CTL following highly active antiretroviral therapy. Immunology 118: 25-38.
-
(2006)
Immunology
, vol.118
, pp. 25-38
-
-
Weekes, M.P.1
Wills, M.R.2
Sissons, J.G.3
Carmichael, A.J.4
|