Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester

Platelets

Volumn 12, Issue 8, 2001, Pages 476-485

  Stafford, Margaret J ^a   Atkinson, Ben T ^b   Watson, Steve P ^b   Pears, Catherine J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CALCIMYCIN; CALCIUM; CALCIUM IONOPHORE; G PROTEIN COUPLED RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE C; PURINE P2Y RECEPTOR;

ARTICLE; CONCENTRATION RESPONSE; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NORMAL HUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOSINE DIPHOSPHATE; ANDROSTADIENES; CALCIMYCIN; CALCIUM SIGNALING; CHROMONES; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; ENZYME ACTIVATION; HUMANS; INDOLES; IONOPHORES; MORPHOLINES; PHOSPHOLIPASE C; PLATELET AGGREGATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN KINASE C; SEROTONIN; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; THROMBOXANES;

EID: 0035662729     PISSN: 09537104     EISSN: None     Source Type: Journal    
DOI: 10.1080/095371001317126374     Document Type: Article

References (18)

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3. 2+ and phorbol esters stimulate platelet aggregation and secretion synergistically through protein kinase C
4. 2+ and protein kinase C is the major factor in determining the level of secretion from human platelets
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