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Volumn 50, Issue 3, 2010, Pages 260-267

Interferon-alpha, -beta and -gamma induce CXCL9 and CXCL10 secretion by human thyrocytes: Modulation by peroxisome proliferator-activated receptor-gamma agonists

Author keywords

CXCL10; CXCL9; Interpheron alpha; Interpheron beta; Thyroid autoimmunity

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; ROSIGLITAZONE;

EID: 77952534161     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2010.01.009     Document Type: Article
Times cited : (79)

References (44)
  • 2
    • 0036828783 scopus 로고    scopus 로고
    • Course and outcome of hepatitis C
    • Hoofnagle J.H. Course and outcome of hepatitis C. Hepatology 2002, 36:S21-S29.
    • (2002) Hepatology , vol.36
    • Hoofnagle, J.H.1
  • 4
    • 0038168312 scopus 로고    scopus 로고
    • Interferon-alpha and autoimmune thyroid disease
    • Prummel M.F., Laurberg P. Interferon-alpha and autoimmune thyroid disease. Thyroid 2003, 13:547-551.
    • (2003) Thyroid , vol.13 , pp. 547-551
    • Prummel, M.F.1    Laurberg, P.2
  • 5
    • 0030248901 scopus 로고    scopus 로고
    • Side effects of high-dose interferon therapy for chronic hepatitis C
    • Okanoue T., Sakamoto S., Itoh Y., Minami M., Yasui K., Sakamoto M., et al. Side effects of high-dose interferon therapy for chronic hepatitis C. J Hepatol 1996, 25:283-291.
    • (1996) J Hepatol , vol.25 , pp. 283-291
    • Okanoue, T.1    Sakamoto, S.2    Itoh, Y.3    Minami, M.4    Yasui, K.5    Sakamoto, M.6
  • 6
    • 0030039651 scopus 로고    scopus 로고
    • A survey of adverse events in 11,241 patients with chronic viral hepatitis treated with alfa interferon
    • Fattovich G., Giustina G., Favarato S., Ruol A. A survey of adverse events in 11,241 patients with chronic viral hepatitis treated with alfa interferon. J Hepatol 1996, 24:38-47.
    • (1996) J Hepatol , vol.24 , pp. 38-47
    • Fattovich, G.1    Giustina, G.2    Favarato, S.3    Ruol, A.4
  • 7
    • 0031465313 scopus 로고    scopus 로고
    • Interferon-alpha induced thyroid dysfunction: three clinical presentations and a review of the literature
    • Koh L.K., Greenspan F.S., Yeo P.P. Interferon-alpha induced thyroid dysfunction: three clinical presentations and a review of the literature. Thyroid 1997, 7:891-896.
    • (1997) Thyroid , vol.7 , pp. 891-896
    • Koh, L.K.1    Greenspan, F.S.2    Yeo, P.P.3
  • 8
    • 2342576258 scopus 로고    scopus 로고
    • Thyroid autoimmunity and dysfunction associated with type I interferon therapy
    • Monzani F., Caraccio N., Dardano A., Ferrannini E. Thyroid autoimmunity and dysfunction associated with type I interferon therapy. Clin Exp Med 2004, 3:199-210.
    • (2004) Clin Exp Med , vol.3 , pp. 199-210
    • Monzani, F.1    Caraccio, N.2    Dardano, A.3    Ferrannini, E.4
  • 9
    • 18544371654 scopus 로고    scopus 로고
    • Discordant effect of IFN- 1a therapy on anti-IFN antibodies and thyroid disease development in patients with multiple sclerosis
    • Monzani F., Meucci G., Caraccio N., Saviozzi M., Casolaro A., Moscato G., et al. Discordant effect of IFN- 1a therapy on anti-IFN antibodies and thyroid disease development in patients with multiple sclerosis. J Interf Cytok Res 2002, 22:773-781.
    • (2002) J Interf Cytok Res , vol.22 , pp. 773-781
    • Monzani, F.1    Meucci, G.2    Caraccio, N.3    Saviozzi, M.4    Casolaro, A.5    Moscato, G.6
  • 10
    • 0142010666 scopus 로고    scopus 로고
    • Interferon alpha treatment and endocrine disease
    • Chan W.B., Chow C.C., Cockram C.S. Interferon alpha treatment and endocrine disease. J R Soc Med 2003, 96:481-485.
    • (2003) J R Soc Med , vol.96 , pp. 481-485
    • Chan, W.B.1    Chow, C.C.2    Cockram, C.S.3
  • 11
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: a new classification system and their role in immunity
    • Zlotnik A., Yoshle O. Chemokines: a new classification system and their role in immunity. Immunity 2000, 12:121-127.
    • (2000) Immunity , vol.12 , pp. 121-127
    • Zlotnik, A.1    Yoshle, O.2
  • 13
    • 0036317941 scopus 로고    scopus 로고
    • Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease
    • Romagnani P., Rotondi M., Lazzeri E., Lasagni L., Francalanci M., Buonamano A., et al. Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease. Am J Pathol 2002, 161:195-206.
    • (2002) Am J Pathol , vol.161 , pp. 195-206
    • Romagnani, P.1    Rotondi, M.2    Lazzeri, E.3    Lasagni, L.4    Francalanci, M.5    Buonamano, A.6
  • 14
    • 0034751864 scopus 로고    scopus 로고
    • Thyrocytes from autoimmune thyroid disorders produce the chemokines IP-10 and Mig and attract CXCR3+ lymphocytes
    • Garcia-Lopez M.A., Sancho D., Sanchez-Madrid F., Marazuela M. Thyrocytes from autoimmune thyroid disorders produce the chemokines IP-10 and Mig and attract CXCR3+ lymphocytes. J Clin Endocr Metab 2001, 86:5008-5016.
    • (2001) J Clin Endocr Metab , vol.86 , pp. 5008-5016
    • Garcia-Lopez, M.A.1    Sancho, D.2    Sanchez-Madrid, F.3    Marazuela, M.4
  • 16
    • 32544456285 scopus 로고    scopus 로고
    • Interferon-gamma-inducible alpha-chemokine CXCL10 involvement in Graves' ophthalmopathy: modulation by peroxisome proliferator-activated receptor-gamma agonists
    • Antonelli A., Rotondi M., Ferrari S.M., Fallahi P., Romagnani P., Franceschini S.S., et al. Interferon-gamma-inducible alpha-chemokine CXCL10 involvement in Graves' ophthalmopathy: modulation by peroxisome proliferator-activated receptor-gamma agonists. J Clin Endocr Metab 2006, 91:614-620.
    • (2006) J Clin Endocr Metab , vol.91 , pp. 614-620
    • Antonelli, A.1    Rotondi, M.2    Ferrari, S.M.3    Fallahi, P.4    Romagnani, P.5    Franceschini, S.S.6
  • 17
    • 66149120609 scopus 로고    scopus 로고
    • Monokine induced by interferon gamma (IFNgamma) (CXCL9) and IFNgamma inducible T-cell alpha-chemoattractant (CXCL11) involvement in Graves' disease and ophthalmopathy: modulation by peroxisome proliferator-activated receptor-gamma agonists
    • Antonelli A., Ferrari S.M., Fallahi P., Frascerra S., Santini E., Franceschini S.S., et al. Monokine induced by interferon gamma (IFNgamma) (CXCL9) and IFNgamma inducible T-cell alpha-chemoattractant (CXCL11) involvement in Graves' disease and ophthalmopathy: modulation by peroxisome proliferator-activated receptor-gamma agonists. J Clin Endocrinol Metab 2009, 94:1803-1809.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1803-1809
    • Antonelli, A.1    Ferrari, S.M.2    Fallahi, P.3    Frascerra, S.4    Santini, E.5    Franceschini, S.S.6
  • 18
    • 8744246379 scopus 로고    scopus 로고
    • High levels of circulating CXC chemokine ligand 10 are associated with chronic autoimmune thyroiditis and hypothyroidism
    • Antonelli A., Rotondi M., Fallahi P., Romagnani P., Ferrari S.M., Buonamano A., et al. High levels of circulating CXC chemokine ligand 10 are associated with chronic autoimmune thyroiditis and hypothyroidism. J Clin Endocr Metab 2004, 89:5496-5499.
    • (2004) J Clin Endocr Metab , vol.89 , pp. 5496-5499
    • Antonelli, A.1    Rotondi, M.2    Fallahi, P.3    Romagnani, P.4    Ferrari, S.M.5    Buonamano, A.6
  • 19
    • 14644400534 scopus 로고    scopus 로고
    • Increase of interferon-gamma inducible alpha chemokine CXCL10 but not beta chemokine CCL2 serum levels in chronic autoimmune thyroiditis
    • Antonelli A., Rotondi M., Fallahi P., Romagnani P., Ferrari S.M., Paolicchi A., et al. Increase of interferon-gamma inducible alpha chemokine CXCL10 but not beta chemokine CCL2 serum levels in chronic autoimmune thyroiditis. Eur J Endocrinol 2005, 152:171-177.
    • (2005) Eur J Endocrinol , vol.152 , pp. 171-177
    • Antonelli, A.1    Rotondi, M.2    Fallahi, P.3    Romagnani, P.4    Ferrari, S.M.5    Paolicchi, A.6
  • 20
    • 34250208691 scopus 로고    scopus 로고
    • Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies
    • Proost P., Struyf S., Loos T., Gouwy M., Schutyser E., Conings R., et al. Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies. Arthritis Res Ther 2006, 8:R107.
    • (2006) Arthritis Res Ther , vol.8
    • Proost, P.1    Struyf, S.2    Loos, T.3    Gouwy, M.4    Schutyser, E.5    Conings, R.6
  • 21
    • 0034522512 scopus 로고    scopus 로고
    • Expression and regulation of the CXC-chemokines, GRO/KC and IP-10/mob-1 in rat seminiferous tubules
    • Aubry F., Habasque C., Satie A.P., Jégou B., Samson M. Expression and regulation of the CXC-chemokines, GRO/KC and IP-10/mob-1 in rat seminiferous tubules. Eur Cytokine Netw 2000, 11:690-698.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 690-698
    • Aubry, F.1    Habasque, C.2    Satie, A.P.3    Jégou, B.4    Samson, M.5
  • 22
    • 0142093064 scopus 로고    scopus 로고
    • Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis
    • Veckman V., Miettinen M., Matikainen S., Lande R., Giacomini E., Coccia E.M., et al. Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis. J Leukocyte Biol 2003, 74:395-402.
    • (2003) J Leukocyte Biol , vol.74 , pp. 395-402
    • Veckman, V.1    Miettinen, M.2    Matikainen, S.3    Lande, R.4    Giacomini, E.5    Coccia, E.M.6
  • 23
    • 0034660182 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells
    • Marx N., Mach F., Sauty A., Leung J.H., Sarafi M.N., Ransohoff R.M., et al. Peroxisome proliferator-activated receptor-activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells. J Immunol 2000, 164:6503-6508.
    • (2000) J Immunol , vol.164 , pp. 6503-6508
    • Marx, N.1    Mach, F.2    Sauty, A.3    Leung, J.H.4    Sarafi, M.N.5    Ransohoff, R.M.6
  • 24
    • 9444260922 scopus 로고    scopus 로고
    • Effect of PPAR- activation and inhibition on glucose-stimulated insulin release in INS-1e cells
    • Santini E., Fallahi P., Ferrari S.M., Masoni A., Antonelli A., Ferrannini E. Effect of PPAR- activation and inhibition on glucose-stimulated insulin release in INS-1e cells. Diabetes 2004, 53(Suppl. 3):S79-S83.
    • (2004) Diabetes , vol.53 , Issue.3 SUPPL.
    • Santini, E.1    Fallahi, P.2    Ferrari, S.M.3    Masoni, A.4    Antonelli, A.5    Ferrannini, E.6
  • 25
    • 0035134688 scopus 로고    scopus 로고
    • Interferon in oncological practice. review of interferon biology, clinical applications, and toxicities
    • Jonasch E., Haluska F.G. Interferon in oncological practice. review of interferon biology, clinical applications, and toxicities. Oncologist 2001, 6:34-55.
    • (2001) Oncologist , vol.6 , pp. 34-55
    • Jonasch, E.1    Haluska, F.G.2
  • 26
    • 0029558511 scopus 로고
    • Immune-mediated side effects of cytokines in humans
    • Vial T., Descotes J. Immune-mediated side effects of cytokines in humans. Toxicology 1995, 105:31-57.
    • (1995) Toxicology , vol.105 , pp. 31-57
    • Vial, T.1    Descotes, J.2
  • 27
    • 0027436442 scopus 로고
    • Reversible inhibition by interferons and of 125I incorporation and thyroid hormone release by human thyroid follicles in vitro
    • Yamazaki K., Kanaji Y., Shizume K., Yamakawa Y., Demura H., Kanaji Y., et al. Reversible inhibition by interferons and of 125I incorporation and thyroid hormone release by human thyroid follicles in vitro. J Clin Endocr Metab 1993, 77:1439-1441.
    • (1993) J Clin Endocr Metab , vol.77 , pp. 1439-1441
    • Yamazaki, K.1    Kanaji, Y.2    Shizume, K.3    Yamakawa, Y.4    Demura, H.5    Kanaji, Y.6
  • 28
    • 0030279780 scopus 로고    scopus 로고
    • Multiple changes in thyroid function in patients with chronic active HCV hepatitis treated with recombinant interferon-alpha
    • Roti E., Minelli R., Giuberti T., Marchelli S., Schianchi C., Gardini E., et al. Multiple changes in thyroid function in patients with chronic active HCV hepatitis treated with recombinant interferon-alpha. Am J Med 1996, 101:482-487.
    • (1996) Am J Med , vol.101 , pp. 482-487
    • Roti, E.1    Minelli, R.2    Giuberti, T.3    Marchelli, S.4    Schianchi, C.5    Gardini, E.6
  • 29
    • 20044367114 scopus 로고    scopus 로고
    • Type I interferons modulate the expression of thyroid peroxidase, sodium/iodide symporter, and thyroglobulin genes in primary human thyrocyte cultures
    • Caraccio N., Giannini R., Cuccato S., Faviana P., Berti P., Galleri D., et al. Type I interferons modulate the expression of thyroid peroxidase, sodium/iodide symporter, and thyroglobulin genes in primary human thyrocyte cultures. J Clin Endocr Metab 2005, 90:1156-1162.
    • (2005) J Clin Endocr Metab , vol.90 , pp. 1156-1162
    • Caraccio, N.1    Giannini, R.2    Cuccato, S.3    Faviana, P.4    Berti, P.5    Galleri, D.6
  • 30
    • 33645037851 scopus 로고    scopus 로고
    • Increase of interferon-gamma-inducible CXC chemokine CXCL10 serum levels in patients with active Graves' disease, and modulation by methimazole therapy
    • Antonelli A., Rotondi M., Fallahi P., Romagnani P., Ferrari S.M., Barani L., et al. Increase of interferon-gamma-inducible CXC chemokine CXCL10 serum levels in patients with active Graves' disease, and modulation by methimazole therapy. Clin Endocrinol (Oxf) 2006, 64:189-195.
    • (2006) Clin Endocrinol (Oxf) , vol.64 , pp. 189-195
    • Antonelli, A.1    Rotondi, M.2    Fallahi, P.3    Romagnani, P.4    Ferrari, S.M.5    Barani, L.6
  • 31
    • 33749589416 scopus 로고    scopus 로고
    • Serum levels of the interferon-gamma-inducible alpha chemokine CXCL10 in patients with active Graves' disease, and modulation by methimazole therapy and thyroidectomy
    • Antonelli A., Fallahi P., Rotondi M., Ferrari S.M., Serio M., Miccoli P. Serum levels of the interferon-gamma-inducible alpha chemokine CXCL10 in patients with active Graves' disease, and modulation by methimazole therapy and thyroidectomy. Brit J Surg 2006, 93:1226-1231.
    • (2006) Brit J Surg , vol.93 , pp. 1226-1231
    • Antonelli, A.1    Fallahi, P.2    Rotondi, M.3    Ferrari, S.M.4    Serio, M.5    Miccoli, P.6
  • 32
    • 34147096595 scopus 로고    scopus 로고
    • Iodine-131 given for therapeutic purposes modulates differently interferon-gamma-inducible alpha-chemokine CXCL10 serum levels in patients with active Graves' disease or toxic nodular goiter
    • Antonelli A., Rotondi M., Fallahi P., Grosso M., Boni G., Ferrari S.M., et al. Iodine-131 given for therapeutic purposes modulates differently interferon-gamma-inducible alpha-chemokine CXCL10 serum levels in patients with active Graves' disease or toxic nodular goiter. J Clin Endocr Metab 2007, 92:1485-1490.
    • (2007) J Clin Endocr Metab , vol.92 , pp. 1485-1490
    • Antonelli, A.1    Rotondi, M.2    Fallahi, P.3    Grosso, M.4    Boni, G.5    Ferrari, S.M.6
  • 33
    • 33744518678 scopus 로고    scopus 로고
    • Increased serum CXCL10 in Graves' disease or autoimmune thyroiditis is not associated with hyper- or hypothyroidism per se, but is specifically sustained by the autoimmune, inflammatory process
    • Antonelli A., Fallahi P., Rotondi M., Ferrari S.M., Romagnani P., Grosso M., et al. Increased serum CXCL10 in Graves' disease or autoimmune thyroiditis is not associated with hyper- or hypothyroidism per se, but is specifically sustained by the autoimmune, inflammatory process. Eur J Endocrinol 2006, 154:651-658.
    • (2006) Eur J Endocrinol , vol.154 , pp. 651-658
    • Antonelli, A.1    Fallahi, P.2    Rotondi, M.3    Ferrari, S.M.4    Romagnani, P.5    Grosso, M.6
  • 34
    • 0038408551 scopus 로고    scopus 로고
    • Pharmacokinetics of ribavirin in combined interferon-alpha 2b and ribavirin therapy for chronic hepatitis C virus infection
    • Tsubota A., Hirose Y., Izumi N., Kumada H. Pharmacokinetics of ribavirin in combined interferon-alpha 2b and ribavirin therapy for chronic hepatitis C virus infection. Br J Clin Pharmacol 2003, 55:360-367.
    • (2003) Br J Clin Pharmacol , vol.55 , pp. 360-367
    • Tsubota, A.1    Hirose, Y.2    Izumi, N.3    Kumada, H.4
  • 36
    • 6344238663 scopus 로고    scopus 로고
    • A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21
    • Martin A.P., Coronel E.C., Sano G., Chen S.C., Vassileva G., Canasto-Chibuque C., et al. A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21. J Immunol 2004, 173:4791-4798.
    • (2004) J Immunol , vol.173 , pp. 4791-4798
    • Martin, A.P.1    Coronel, E.C.2    Sano, G.3    Chen, S.C.4    Vassileva, G.5    Canasto-Chibuque, C.6
  • 38
    • 0025027271 scopus 로고
    • Effects of interferon-gamma therapy on thyroid function, T-lymphocyte subpopulations and induction of autoantibodies
    • Kung A.W., Jones B.M., Lai C.L. Effects of interferon-gamma therapy on thyroid function, T-lymphocyte subpopulations and induction of autoantibodies. J Clin Endocrinol Metab 1990, 71(5):1230-1234.
    • (1990) J Clin Endocrinol Metab , vol.71 , Issue.5 , pp. 1230-1234
    • Kung, A.W.1    Jones, B.M.2    Lai, C.L.3
  • 39
    • 0025203837 scopus 로고
    • Clinical pharmacokinetics of interferons
    • Wills R.J. Clinical pharmacokinetics of interferons. Clin Pharmacokinet 1990, 19(5):390-399.
    • (1990) Clin Pharmacokinet , vol.19 , Issue.5 , pp. 390-399
    • Wills, R.J.1
  • 40
    • 0034777941 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators affect the maturation of human monocyte-derived dendritic cells
    • Gosset P., Charbonnier A.S., Delerive P., Fontaine J., Staels B., Pestel J., et al. Peroxisome proliferator-activated receptor gamma activators affect the maturation of human monocyte-derived dendritic cells. Eur J Immunol 2001, 31:2857-2865.
    • (2001) Eur J Immunol , vol.31 , pp. 2857-2865
    • Gosset, P.1    Charbonnier, A.S.2    Delerive, P.3    Fontaine, J.4    Staels, B.5    Pestel, J.6
  • 41
    • 15944363392 scopus 로고    scopus 로고
    • Intestinal antiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptor-gamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms
    • Schaefer K.L., Denevich S., Ma C., Cooley S.R., Nakajima A., Wada K., et al. Intestinal antiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptor-gamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms. Inflamm Bowel Dis 2005, 11:244-252.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 244-252
    • Schaefer, K.L.1    Denevich, S.2    Ma, C.3    Cooley, S.R.4    Nakajima, A.5    Wada, K.6
  • 42
    • 0032746173 scopus 로고    scopus 로고
    • A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response
    • Su C.G., Wen X., Bailey S.T., Jiang W., Rangwala S.M., Keilbaugh S.A., et al. A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response. J Clin Invest 1999, 104:383-389.
    • (1999) J Clin Invest , vol.104 , pp. 383-389
    • Su, C.G.1    Wen, X.2    Bailey, S.T.3    Jiang, W.4    Rangwala, S.M.5    Keilbaugh, S.A.6
  • 43
    • 42249089079 scopus 로고    scopus 로고
    • A new mechanism involving ERK contributes to rosiglitazone inhibition of tumor necrosis factor-alpha and interferon-gamma inflammatory effects in human endothelial cells
    • Lombardi A., Cantini G., Piscitelli E., Gelmini S., Francalanci M., Mello T., et al. A new mechanism involving ERK contributes to rosiglitazone inhibition of tumor necrosis factor-alpha and interferon-gamma inflammatory effects in human endothelial cells. Arterioscl Throm Vas 2008, 28:718-724.
    • (2008) Arterioscl Throm Vas , vol.28 , pp. 718-724
    • Lombardi, A.1    Cantini, G.2    Piscitelli, E.3    Gelmini, S.4    Francalanci, M.5    Mello, T.6
  • 44
    • 41149086163 scopus 로고    scopus 로고
    • Regulation of lymphocyte function by PPARgamma: relevance to thyroid eye disease-related inflammation
    • Lehmann G.M., Garcia-Bates T.M., Smith T.J., Feldon S.E., Phipps R.P. Regulation of lymphocyte function by PPARgamma: relevance to thyroid eye disease-related inflammation. PPAR Res 2008, 2008:895901.
    • (2008) PPAR Res , vol.2008 , pp. 895901
    • Lehmann, G.M.1    Garcia-Bates, T.M.2    Smith, T.J.3    Feldon, S.E.4    Phipps, R.P.5


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