IgG4-related systemic disease: Emergence of a new systemic disease? Literature review.;Maladie systémique associée aux IgG4: Une pathologie émergente? Mise aupoint et revue de la littérature

Revue de Medecine Interne

Volumn 33, Issue 1, 2012, Pages 23-34

  Ebbo, M ^a   Grados, A ^a   Daniel, L ^b   Vely F ^a   Harle J R ^a   Pavic, M ^c   Schleinitz, N ^a  

^a HÔPITAL DE LA CONCEPTION   (France)

^b TIMONE HOSPITAL   (France)

^c HIA Desgenettes   (France)

Author keywords

Autoimmune pancreatitis; Fibrosis; IgG4; IgG4 related systemic disease; Tubulointerstitial nephritis

Indexed keywords

CORTICOSTEROID; IMMUNOGLOBULIN G4;

AORTITIS; AUTOIMMUNE PANCREATITIS; HISTOPATHOLOGY; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN G DEFICIENCY; INTERSTITIAL NEPHRITIS; LACRIMAL GLAND; LYMPHADENOPATHY; LYMPHOCYTIC INFILTRATION; PATHOPHYSIOLOGY; PSEUDOTUMOR; RETROPERITONEAL FIBROSIS; SCLEROSING CHOLANGITIS; SHORT SURVEY; SIALOADENITIS;

AUTOIMMUNE DISEASES; CHOLANGITIS, SCLEROSING; HUMANS; HYPERGAMMAGLOBULINEMIA; IMMUNOGLOBULIN G; PANCREATITIS;

EID: 84855194936     PISSN: 02488663     EISSN: 17683122     Source Type: Journal    
DOI: 10.1016/j.revmed.2011.08.012     Document Type: Short Survey

References (137)

1. Sarles H., Sarles J.C., Muratore R., Guien C. Chronic inflammatory sclerosis of the pancreas-an autonomous pancreatic disease?. Am J Dig Dis 1961, 6:688-698.
2. Yoshida K., Toki F., Takeuchi T., Watanabe S., Shiratori K., Hayashi N. Chronic pancreatitis caused by an autoimmune abnormality. Proposal of the concept of autoimmune pancreatitis. Dig Dis Sci 1995, 40:1561-1568.
3. Hamano H., Kawa S., Horiuchi A., Unno H., Furuya N., Akamatsu T., et al. High serum IgG4concentrations in patients with sclerosing pancreatitis. N Engl J Med 2001, 344:732-738.
4. Hamano H., Kawa S., Ochi Y., Unno H., Shiba N., Wajiki M., et al. Hydronephrosis associated with retroperitoneal fibrosis and sclerosing pancreatitis. Lancet 2002, 359:1403-1404.
5. Kamisawa T., Funata N., Hayashi Y. Lymphoplasmacytic sclerosing pancreatitis is a pancreatic lesion of IgG4-related systemic disease. Am J Surg Pathol 2004, 28:1114.
6. Kamisawa T., Nakajima H., Egawa N., Funata N., Tsuruta K., Okamoto A. IgG4-related sclerosing disease incorporating sclerosing pancreatitis, cholangitis, sialadenitis and retroperitoneal fibrosis with lymphadenopathy. Pancreatology 2006, 6:132-137.
7. Kamisawa T., Funata N., Hayashi Y., Tsuruta K., Okamoto A., Amemiya K., et al. Close relationship between autoimmune pancreatitis and multifocal fibrosclerosis. Gut 2003, 52:683-687.
8. Kamisawa T., Funata N., Hayashi Y., Eishi Y., Koike M., Tsuruta K., et al. A new clinicopathological entity of IgG4-related autoimmune disease. J Gastroenterol 2003, 38:982-984.
9. Neild G.H., Rodriguez-Justo M., Wall C., Connolly J.O. Hyper-IgG4disease: report and characterisation of a new disease. BMC Med 2006, 4:23.
10. Saeki T., Saito A., Hiura T., Yamazaki H., Emura I., Ueno M., et al. Lymphoplasmacytic infiltration of multiple organs with immunoreactivity for IgG4: IgG4-related systemic disease. Intern Med 2006, 45:163-167.
11. Yamamoto M., Takahashi H., Naishiro Y., Isshiki H., Ohara M., Suzuki C., et al. Mikulicz's disease and systemic IgG4-related plasmacytic syndrome (SIPS). Nihon Rinsho Meneki Gakkai Kaishi 2008, 31:1-8.
12. Masaki Y., Dong L., Kurose N., Kitagawa K., Morikawa Y., Yamamoto M., et al. Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome: analysis of 64cases of IgG4-related disorders. Ann Rheum Dis 2009, 68:1310-1315.
13. Stone J.H., Caruso P.A., Deshpande V. Case records of the Massachusetts General Hospital. Case 24-2009. A 26-year-old woman with painful swelling of the neck. N Engl J Med 2009, 361:511-518.
14. Stone J.H., Khosroshahi A., Hilgenberg A., Spooner A., Isselbacher E.M., Stone J.R. IgG4-related systemic disease and lymphoplasmacytic aortitis. Arthritis Rheum 2009, 60:3139-3145.
15. Stone J.H., Khosroshahi A., Deshpande V., Stone J.R. IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases. Arthritis Care Res 2010, 62:316-322.
16. Khosroshahi A., Bloch D.B., Deshpande V., Stone J.H. Rituximab therapy leads to rapid decline of serum IgG4levels and prompt clinical improvement in IgG4-related systemic disease. Arthritis Rheum 2010, 62:1755-1762.
17. Ebbo M, Daniel L, Pavic M, Sève P, Hamidou M, Andres E, et al. IgG4-related systemic disease: clinical, biological, histological features and treatment response in a French cohort. Results of a Multicenter Registry. Medicine (Baltimore) 2011 [In press].
18. Nishimori I., Tamakoshi A., Otsuki M. Prevalence of autoimmune pancreatitis in Japan from a nationwide survey in 2002. J Gastroenterol 2007, 42(Suppl.18):6-8.
19. Kim K.P., Kim M.H., Song M.H., Lee S.S., Seo D.W., Lee S.K. Autoimmune chronic pancreatitis. Am J Gastroenterol 2004, 99:1605-1616.
20. Bach J.F. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002, 347:911-920.
21. Kamisawa T., Okamoto A. IgG4-related sclerosing disease. World J Gastroenterol 2008, 14:3948-3955.
22. Chari S.T., Takahashi N., Levy M.J., Smyrk T.C., Clain J.E., Pearson R.K., et al. A diagnostic strategy to distinguish autoimmune pancreatitis from pancreatic cancer. Clin Gastroenterol Hepatol 2009, 7:1097-1103.
23. Okazaki K., Kawa S., Kamisawa T., Shimosegawa T., Tanaka M. Japanese consensus guidelines for management of autoimmune pancreatitis: I. Concept and diagnosis of autoimmune pancreatitis. J Gastroenterol 2010, 45:249-265.
24. Okazaki K., Kawa S., Kamisawa T., Naruse S., Tanaka S., Nishimori I., et al. Clinical diagnostic criteria of autoimmune pancreatitis: revised proposal. J Gastroenterol 2006, 41:626-631.
25. Hardacre J.M., Iacobuzio-Donahue C.A., Sohn T.A., Abraham S.C., Yeo C.J., Lillemoe K.D., et al. Results of pancreaticoduodenectomy for lymphoplasmacytic sclerosing pancreatitis. Ann Surg 2003, 237:853-858. [discussion 858-9].
26. Kamisawa T., Imai M., Yui Chen P., Tu Y., Egawa N., Tsuruta K., et al. Strategy for differentiating autoimmune pancreatitis from pancreatic cancer. Pancreas 2008, 37:e62-e67.
27. Chari S.T., Kloeppel G., Zhang L., Notohara K., Lerch M.M., Shimosegawa T. Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document. Pancreatology 2010, 10:664-672.
28. Kamisawa T., Takuma K., Anjiki H., Egawa N., Kurata M., Honda G., et al. Sclerosing cholangitis associated with autoimmune pancreatitis differs from primary sclerosing cholangitis. World J Gastroenterol 2009, 15:2357-2360.
29. Hayashi K., Nakazawa T., Ohara H., Ando T., Takada H., Tanaka H., et al. Autoimmune sclerosing cholangiopancreatitis with little pancreatic involvements by imaging findings. Hepatogastroenterology 2007, 54:2146-2151.
30. Nishino T., Oyama H., Hashimoto E., Toki F., Oi I., Kobayashi M., et al. Clinicopathological differentiation between sclerosing cholangitis with autoimmune pancreatitis and primary sclerosing cholangitis. J Gastroenterol 2007, 42:550-559.
31. Bjornsson E., Chari S., Silveira M., Gossard A., Takahashi N., Smyrk T., et al. Primary sclerosing cholangitis associated with elevated immunoglobulinG4: clinical characteristics and response to therapy. Am J Ther 2011, 18:198-205.
32. Nakazawa T., Ohara H., Sano H., Ando T., Joh T. Schematic classification of sclerosing cholangitis with autoimmune pancreatitis by cholangiography. Pancreas 2006, 32:229.
33. Naitoh I., Nakazawa T., Ohara H., Ando T., Hayashi K., Tanaka H., et al. Endoscopic transpapillary intraductal ultrasonography and biopsy in the diagnosis of IgG4-related sclerosing cholangitis. J Gastroenterol 2009, 44:1147-1155.
34. Ghazale A., Chari S.T., Zhang L., Smyrk T.C., Takahashi N., Levy M.J., et al. Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy. Gastroenterology 2008, 134:706-715.
35. Geyer J.T., Ferry J.A., Harris N.L., Stone J.H., Zukerberg L.R., Lauwers G.Y., et al. Chronic sclerosing sialadenitis (Kuttner tumor) is an IgG4-associated disease. Am J Surg Pathol 2010, 34:202-210.
36. Geyer J.T., Deshpande V. IgG4-associated sialadenitis. Curr Opin Rheumatol 2011, 23:95-101.
37. Morgan W.S. The probable systemic nature of Mikulicz's disease and its relation to Sjogren's syndrome. N Engl J Med 1954, 251:5-10.
38. Watson S.J., Jenkins D.A., Bellamy C.O. Nephropathy in IgG4-related systemic disease. Am J Surg Pathol 2006, 30:1472-1477.
39. Cornell L.D., Chicano S.L., Deshpande V., Collins A.B., Selig M.K., Lauwers G.Y., et al. Pseudotumors due to IgG4immune-complex tubulointerstitial nephritis associated with autoimmune pancreatocentric disease. Am J Surg Pathol 2007, 31:1586-1597.
40. Saeki T., Nishi S., Ito T., Yamazaki H., Miyamura S., Emura I., et al. Renal lesions in IgG4-related systemic disease. Intern Med 2007, 46:1365-1371.
41. Saeki T., Nishi S., Imai N., Ito T., Yamazaki H., Kawano M., et al. Clinicopathological characteristics of patients with IgG4-related tubulointerstitial nephritis. Kidney Int 2010, 78:1016-1023.
42. Raissian Y., Nasr S.H., Larsen C.P., Colvin R.B., Smyrk T.C., Takahashi N., et al. Diagnosis of IgG4-related tubulointerstitial nephritis. J Am Soc Nephrol 2011, 22:1343-1352.
43. Hamano H., Arakura N., Muraki T., Ozaki Y., Kiyosawa K., Kawa S. Prevalence and distribution of extrapancreatic lesions complicating autoimmune pancreatitis. J Gastroenterol 2006, 41:1197-1205.
44. Sato Y., Kojima M., Takata K., Morito T., Asaoku H., Takeuchi T., et al. Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castleman's disease. Mod Pathol 2009, 22:589-599.
45. Sato Y., Notohara K., Kojima M., Takata K., Masaki Y., Yoshino T. IgG4-related disease: historical overview and pathology of hematological disorders. Pathol Int 2010, 60:247-258.
46. Sato Y., Kojima M., Takata K., Morito T., Mizobuchi K., Tanaka T., et al. Multicentric Castleman's disease with abundant IgG4-positive cells: a clinical and pathological analysis of six cases. J Clin Pathol 2010, 63:1084-1089.
47. Cheuk W., Yuen H.K., Chu S.Y., Chiu E.K., Lam L.K., Chan J.K. Lymphadenopathy of IgG4-related sclerosing disease. Am J Surg Pathol 2008, 32:671-681.
48. Zen Y., Onodera M., Inoue D., Kitao A., Matsui O., Nohara T., et al. Retroperitoneal fibrosis: a clinicopathologic study with respect to immunoglobulin G4. Am J Surg Pathol 2009, 33:1833-1839.
49. Taniguchi T., Kobayashi H., Fukui S., Ogura K., Saiga T., Okamoto M. A case of multifocal fibrosclerosis involving posterior mediastinal fibrosis, retroperitoneal fibrosis, and a left seminal vesicle with elevated serum IgG4. Hum Pathol 2006, 37:1237-1239. [author reply 1239].
50. Chen T.S., Montgomery E.A. Are tumefactive lesions classified as sclerosing mesenteritis a subset of IgG4-related sclerosing disorders?. J Clin Pathol 2008, 61:1093-1097.
51. Dahlgren M., Khosroshahi A., Nielsen G.P., Deshpande V., Stone J.H. Riedel's thyroiditis and multifocal fibrosclerosis are part of the IgG4-related systemic disease spectrum. Arthritis Care Res 2010, 62:1312-1318.
52. Stone J.R. Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of IgG4-related systemic disease. Curr Opin Rheumatol 2011, 23:88-94.
53. Kasashima S., Zen Y., Kawashima A., Endo M., Matsumoto Y., Kasashima F., et al. A clinicopathologic study of immunoglobulin G4-related sclerosing disease of the thoracic aorta. J Vasc Surg 2010, 52:1587-1595.
54. Kasashima S., Zen Y., Kawashima A., Konishi K., Sasaki H., Endo M., et al. Surg Pathol 2008, 32:197-204.
55. Kasashima S., Zen Y. IgG4-related inflammatory abdominal aortic aneurysm. Curr Opin Rheumatol 2011, 23:18-23.
56. Ryu JH, Sekiguchi H, Yi ES. Pulmonary manifestations of IgG4-related sclerosing disease. Eur Respir J 2011 [Epub ahead of print], doi:10.1183/09031936.00025211.
57. Inoue D., Zen Y., Abo H., Gabata T., Demachi H., Kobayashi T., et al. Immunoglobulin G4-related lung disease: CT findings with pathologic correlations. Radiology 2009, 251:260-270.
58. Tsushima K., Yokoyama T., Kawa S., Hamano H., Tanabe T., Koizumi T., et al. Elevated IgG4levels in patients demonstrating sarcoidosis-like radiologic findings. Medicine (Baltimore) 2011, 90:194-200.
59. Zen Y., Nakanuma Y. IgG4-related disease: a cross-sectional study of 114cases. Am J Surg Pathol 2011, 34:1812-1819.
60. Michel L, Clairand R, Neel A, Masseau A, Frampas E, Hamidou M. Association of IgG4-related disease and sarcoidosis. Thorax 2011 [Epub ahead of print], doi:thx.2011.160341.
61. Li Y., Bai Y., Liu Z., Ozaki T., Taniguchi E., Mori I., et al. Immunohistochemistry of IgG4can help subclassify Hashimoto's autoimmune thyroiditis. Pathol Int 2009, 59:636-641.
62. Li Y., Nishihara E., Kakudo K. Hashimoto's thyroiditis: old concepts and new insights. Curr Opin Rheumatol 2011, 23:102-107.
63. Shimatsu A., Oki Y., Fujisawa I., Sano T. Pituitary and stalk lesions (infundibulo-hypophysitis) associated with immunoglobulin G4-related systemic disease: an emerging clinical entity. Endocr J 2009, 56:1033-1041.
64. Mehta M., Jakobiec F., Fay A. Idiopathic fibroinflammatory disease of the face, eyelids, and periorbital membrane with immunoglobulin G4-positive plasma cells. Arch Pathol Lab Med 2009, 133:1251-1255.
65. Zen Y., Harada K., Sasaki M., Sato Y., Tsuneyama K., Haratake J., et al. IgG4-related sclerosing cholangitis with and without hepatic inflammatory pseudotumor, and sclerosing pancreatitis-associated sclerosing cholangitis: do they belong to a spectrum of sclerosing pancreatitis?. Am J Surg Pathol 2004, 28:1193-1203.
66. Zen Y., Kasahara Y., Horita K., Miyayama S., Miura S., Kitagawa S., et al. Inflammatory pseudotumor of the breast in a patient with a high serum IgG4level: histologic similarity to sclerosing pancreatitis. Am J Surg Pathol 2005, 29:275-278.
67. Cheuk W., Chan A.C., Lam W.L., Chow S.M., Crowley P., Lloydd R., et al. IgG4-related sclerosing mastitis: description of a new member of the IgG4-related sclerosing diseases. Am J Surg Pathol 2009, 33:1058-1064.
68. Zen Y., Kitagawa S., Minato H., Kurumaya H., Katayanagi K., Masuda S., et al. IgG4-positive plasma cells in inflammatory pseudotumor (plasma cell granuloma) of the lung. Hum Pathol 2005, 36:710-717.
69. Chan S.K., Cheuk W., Chan K.T., Chan J.K. IgG4-related sclerosing pachymeningitis: a previously unrecognized form of central nervous system involvement in IgG4-related sclerosing disease. Am J Surg Pathol 2009, 33:1249-1252.
70. Lindstrom K.M., Cousar J.B., Lopes M.B. IgG4-related meningeal disease: clinico-pathological features and proposal for diagnostic criteria. Acta Neuropathol 2010, 120:765-776.
71. Sugimoto T., Morita Y., Isshiki K., Yamamoto T., Uzu T., Kashiwagi A., et al. Constrictive pericarditis as an emerging manifestation of hyper-IgG4disease. Int J Cardiol 2008, 130:e100-e101.
72. Yoshimura Y., Takeda S., Ieki Y., Takazakura E., Koizumi H., Takagawa K. IgG4-associated prostatitis complicating autoimmune pancreatitis. Intern Med 2006, 45:897-901.
73. Cheuk W., Lee K.C., Chong L.Y., Yuen S.T., Chan J.K. IgG4-related Sclerosing disease: a potential new etiology of cutaneous pseudolymphoma. Am J Surg Pathol 2009, 33:1713-1719.
74. Sato M., Okumura T., Shioyama Y., Imura J. Extrapancreatic F-18FDG accumulation in autoimmune pancreatitis. Ann Nucl Med 2008, 22:215-219.
75. Suga K., Kawakami Y., Hiyama A., Hori K., Takeuchi M. F-18FDG PET-CT findings in Mikulicz disease and systemic involvement of IgG4-related lesions. Clin Nucl Med 2009, 34:164-167.
76. Nakajo M., Jinnouchi S., Noguchi M., Uozumi K., Tanabe H., Tateno R., et al. FDG PET and PET/CT monitoring of autoimmune pancreatitis associated with extrapancreatic autoimmune disease. Clin Nucl Med 2007, 32:282-285.
77. Sah R.P., Pannala R., Zhang L., Graham R.P., Sugumar A., Chari S.T. Eosinophilia and allergic disorders in autoimmune pancreatitis. Am J Gastroenterol 2010, 105(11):2485-2491.
78. Witkiewicz A.K., Kennedy E.P., Kennyon L., Yeo C.J., Hruban R.H. Synchronous autoimmune pancreatitis and infiltrating pancreatic ductal adenocarcinoma: case report and review of the literature. Hum Pathol 2008, 39:1548-1551.
79. Cheuk W., Yuen H.K., Chan A.C., Shih L.Y., Kuo T.T., Ma M.W., et al. Ocular adnexal lymphoma associated with IgG4+ chronic sclerosing dacryoadenitis: a previously undescribed complication of IgG4-related sclerosing disease. Am J Surg Pathol 2008, 32:1159-1167.
80. Gill J., Angelo N., Yeong M.L., McIvor N. Salivary duct carcinoma arising in IgG4-related autoimmune disease of the parotid gland. Hum Pathol 2009, 40:881-886.
81. Okazaki K., Uchida K., Fukui T. Recent advances in autoimmune pancreatitis: concept, diagnosis, and pathogenesis. J Gastroenterol 2008, 43:409-418.
82. Asada M., Nishio A., Uchida K., Kido M., Ueno S., Uza N., et al. Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis. Pancreas 2006, 33:20-26.
83. Okazaki K., Uchida K., Ohana M., Nakase H., Uose S., Inai M., et al. Autoimmune-related pancreatitis is associated with autoantibodies and a Th1/Th2-type cellular immune response. Gastroenterology 2000, 118:573-581.
84. Frulloni L., Bovo P., Brunelli S., Vaona B., Di Francesco V., Nishimori I., et al. Elevated serum levels of antibodies to carbonic anhydrase I and II in patients with chronic pancreatitis. Pancreas 2000, 20:382-388.
85. Lohr J.M., Faissner R., Koczan D., Bewerunge P., Bassi C., Brors B., et al. Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process. Am J Gastroenterol 2010, 105:2060-2071.
86. Frulloni L., Lunardi C., Simone R., Dolcino M., Scattolini C., Falconi M., et al. Identification of a novel antibody associated with autoimmune pancreatitis. N Engl J Med 2009, 361:2135-2142.
87. Aucouturier P., Lacombe C., Preud'homme J.L. Serum IgG subclass level determination: methodological difficulties and practical aspects. Ann Biol Clin (Paris) 1994, 52:53-56.
88. Nishino T., Toki F., Oyama H., Shimizu K., Shiratori K. Long-term outcome of autoimmune pancreatitis after oral prednisolone therapy. Intern Med 2006, 45:497-501.
89. Kamisawa T., Shimosegawa T., Okazaki K., Nishino T., Watanabe H., Kanno A., et al. Standard steroid treatment for autoimmune pancreatitis. Gut 2009, 58:1504-1507.
90. Morselli-Labate A.M., Pezzilli R. Usefulness of serum IgG4in the diagnosis and follow-up of autoimmune pancreatitis: a systematic literature review and meta-analysis. J Gastroenterol Hepatol 2009, 24:15-36.
91. Ghazale A., Chari S.T., Smyrk T.C., Levy M.J., Topazian M.D., Takahashi N., et al. Value of serum IgG4in the diagnosis of autoimmune pancreatitis and in distinguishing it from pancreatic cancer. Am J Gastroenterol 2007, 102:1646-1653.
92. Sah R.P., Chari S.T. Serologic issues in IgG4-related systemic disease and autoimmune pancreatitis. Curr Opin Rheumatol 2011, 23:108-113.
93. Aalberse R.C., Van Milligen F., Tan K.Y., Stapel S.O. Allergen-specific IgG4in atopic disease. Allergy 1993, 48:559-569.
94. Hussain R., Poindexter R.W., Ottesen E.A. Control of allergic reactivity in human filariasis. Predominant localization of blocking antibody to the IgG4subclass. J Immunol 1992, 148:2731-2737.
95. Liu L.J., Chen M., Yu F., Zhao M.H., Wang H.Y. IgG subclass distribution, affinity of anti-myeloperoxidase antibodies in sera from patients with Wegener's granulomatosis and microscopic polyangiitis. Nephrology (Carlton) 2008, 13:629-635.
96. Futei Y., Amagai M., Ishii K., Kuroda-Kinoshita K., Ohya K., Nishikawa T. Predominant IgG4subclass in autoantibodies of pemphigus vulgaris and foliaceus. J Dermatol Sci 2001, 26:55-61.
97. Taguchi M., Kihara Y., Nagashio Y., Yamamoto M., Otsuki M., Harada M. Decreased production of immunoglobulin M and A in autoimmune pancreatitis. J Gastroenterol 2009, 44:1133-1139.
98. Saeki T., Ito T., Yamazaki H., Imai N., Nishi S. Hypocomplementemia of unknown etiology: an opportunity to find cases of IgG4-positive multi-organ lymphoproliferative syndrome. Rheumatol Int 2009, 30(1):99-103.
99. Muraki T., Hamano H., Ochi Y., Komatsu K., Komiyama Y., Arakura N., et al. Autoimmune pancreatitis and complement activation system. Pancreas 2006, 32:16-21.
100. Kawa S., Kitahara K., Hamano H., Ozaki Y., Arakura N., Yoshizawa K., et al. A novel immunoglobulin-immunoglobulin interaction in autoimmunity. PLoS One 2008, 3:e1637.
101. Smyrk T.C. Pathological features of IgG4-related sclerosing disease. Curr Opin Rheumatol 2011, 23:74-79.
102. Kojima M., Sipos B., Klapper W., Frahm O., Knuth H.C., Yanagisawa A., et al. Autoimmune pancreatitis: frequency, IgG4expression, and clonality of T and B cells. Am J Surg Pathol 2007, 31:521-528.
103. Zhang L., Notohara K., Levy M.J., Chari S.T., Smyrk T.C. IgG4-positive plasma cell infiltration in the diagnosis of autoimmune pancreatitis. Mod Pathol 2007, 20:23-28.
104. Dhall D., Suriawinata A.A., Tang L.H., Shia J., Klimstra D.S. Use of immunohistochemistry for IgG4in the distinction of autoimmune pancreatitis from peritumoral pancreatitis. Hum Pathol 2010, 41:643-652.
105. Koyabu M., Uchida K., Fukata N., Kusuda T., Ikeura T., Sakaguchi Y., et al. Primary sclerosing cholangitis with elevated serum IgG4levels and/or infiltration of abundant IgG4-positive plasma cells. J Gastroenterol 2010, 45:122-129.
106. Strehl J.D., Hartmann A., Agaimy A. Numerous IgG4-positive plasma cells are ubiquitous in diverse localised non-specific chronic inflammatory conditions and need to be distinguished from IgG4-related systemic disorders. J Clin Pathol 2011, 64(3):237-243.
107. Kim K.P., Kim M.H., Kim J.C., Lee S.S., Seo D.W., Lee S.K. Diagnostic criteria for autoimmune chronic pancreatitis revisited. World J Gastroenterol 2006, 12:2487-2496.
108. Otsuki M., Chung J.B., Okazaki K., Kim M.H., Kamisawa T., Kawa S., et al. Asian diagnostic criteria for autoimmune pancreatitis: consensus of the Japan-Korea Symposium on Autoimmune Pancreatitis. J Gastroenterol 2008, 43:403-408.
109. Chari S.T. Diagnosis of autoimmune pancreatitis using its five cardinal features: introducing the Mayo Clinic's HISORt criteria. J Gastroenterol 2007, 42(Suppl.18):39-41.
110. Alderlieste Y.A., van den Elzen B.D., Rauws E.A., Beuers U. Immunoglobulin G4-associated cholangitis: one variant of immunoglobulin G4-related systemic disease. Digestion 2009, 79:220-228.
111. Okazaki K. Proposal of the concept and diagnostic criteria of IgG4-related disease. In: Annual reports of Research Committee Of Intractable Diseases supported by Ministry of Health, Labour and Welfare of Japan; 2009.
112. Okazaki K., Uchida K., Koyabu M., Miyoshi H., Takaoka M. Recent advances in the concept and diagnosis of autoimmune pancreatitis and IgG4-related disease. J Gastroenterol 2011, 46:277-288.
113. Kawa S., Ota M., Yoshizawa K., Horiuchi A., Hamano H., Ochi Y., et al. HLA DRB10405-DQB10401haplotype is associated with autoimmune pancreatitis in the Japanese population. Gastroenterology 2002, 122:1264-1269.
114. Umemura T., Ota M., Hamano H., Katsuyama Y., Muraki T., Arakura N., et al. Association of autoimmune pancreatitis with cytotoxic T-lymphocyte antigen 4gene polymorphisms in Japanese patients. Am J Gastroenterol 2008, 103:588-594.
115. Umemura T., Ota M., Hamano H., Katsuyama Y., Kiyosawa K., Kawa S. Genetic association of Fc receptor-like 3polymorphisms with autoimmune pancreatitis in Japanese patients. Gut 2006, 55:1367-1368.
116. Umemura T., Katsuyama Y., Hamano H., Kitahara K., Takayama M., Arakura N., et al. Association analysis of Toll-like receptor 4polymorphisms with autoimmune pancreatitis. Hum Immunol 2009, 70:742-746.
117. Boulanger E., Fuentes V., Meignin V., Mougenot B., Labaume S., Gouilleux-Gruart V., et al. Polyclonal IgG4hypergammaglobulinemia associated with plasmacytic lymphadenopathy, anemia and nephropathy. Ann Hematol 2006, 85:833-840.
118. Yamamoto M., Harada S., Ohara M., Suzuki C., Naishiro Y., Yamamoto H., et al. Clinical and pathological differences between Mikulicz's disease and Sjogren's syndrome. Rheumatology (Oxford) 2005, 44:227-234.
119. Miyake K., Moriyama M., Aizawa K., Nagano S., Inoue Y., Sadanaga A., et al. Peripheral CD4+ T cells showing a Th2phenotype in a patient with Mikulicz's disease associated with lymphadenopathy and pleural effusion. Mod Rheumatol 2008, 18:86-90.
120. Kudo-Tanaka E., Nakatsuka S., Hirano T., Kawai M., Katada Y., Matsushita M., et al. A case of Mikulicz's disease with Th2-biased cytokine profile: possible feature discriminable from Sjogren's syndrome. Mod Rheumatol 2009, 19:691-695.
121. Akitake R., Watanabe T., Zaima C., Uza N., Ida H., Tada S., et al. Possible involvement of T helper type 2responses to Toll-like receptor ligands in IgG4-related sclerosing disease. Gut 2010, 59:542-545.
122. Suzuki K., Tamaru J., Okuyama A., Kameda H., Amano K., Nagasawa H., et al. IgG4-positive multi-organ lymphoproliferative syndrome manifesting as chronic symmetrical sclerosing dacryo-sialadenitis with subsequent secondary portal hypertension and remarkable IgG4-linked IL-4elevation. Rheumatology (Oxford) 2010, 49:1789-1791.
123. Zen Y., Fujii T., Harada K., Kawano M., Yamada K., Takahira M., et al. Th2and regulatory immune reactions are increased in immunoglobin G4-related sclerosing pancreatitis and cholangitis. Hepatology 2007, 45:1538-1546.
124. Miyoshi H., Uchida K., Taniguchi T., Yazumi S., Matsushita M., Takaoka M., et al. Circulating naive and CD4+CD25high regulatory T cells in patients with autoimmune pancreatitis. Pancreas 2008, 36:133-140.
125. Koyabu M., Uchida K., Miyoshi H., Sakaguchi Y., Fukui T., Ikeda H., et al. Analysis of regulatory T cells and IgG4-positive plasma cells among patients of IgG4-related sclerosing cholangitis and autoimmune liver diseases. J Gastroenterol 2010, 45:732-741.
126. Nakashima H., Miyake K., Moriyama M., Tanaka A., Watanabe M., Abe Y., et al. An amplification of IL-10and TGF-beta in patients with IgG4-related tubulointerstitial nephritis. Clin Nephrol 2010, 73:385-391.
127. Simpson N., Gatenby P.A., Wilson A., Malik S., Fulcher D.A., Tangye S.G., et al. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum 2010, 62:234-244.
128. Zaidan M., Cervera-Pierot P., de Seigneux S., Dahan K., Fabiani B., Callard P., et al. Evidence of follicular T-cell implication in a case of IgG4-related systemic disease with interstitial nephritis. Nephrol Dial Transplant 2011, 26:2047-2050.
129. Saeki T., Ito T., Youkou A., Ishiguro H., Sato N., Yamazaki H., et al. Thrombotic thrombocytopenic purpura in IgG4-related disease with severe deficiency of ADAMTS-13activity and IgG4autoantibody against ADAMTS-13. Arthritis Care Res 2011, 63:1209-1212.
130. Kubota K., Iida H., Fujisawa T., Yoneda M., Inamori M., Abe Y., et al. Clinical factors predictive of spontaneous remission or relapse in cases of autoimmune pancreatitis. Gastrointest Endosc 2007, 66:1142-1151.
131. Kamisawa T., Okazaki K., Kawa S., Shimosegawa T., Tanaka M. Japanese consensus guidelines for management of autoimmune pancreatitis: III. Treatment and prognosis of AIP. J Gastroenterol 2010, 45:471-477.
132. Pannala R., Chari S.T. Corticosteroid treatment for autoimmune pancreatitis. Gut 2009, 58:1438-1439.
133. Ito T., Nishimori I., Inoue N., Kawabe K., Gibo J., Arita Y., et al. Treatment for autoimmune pancreatitis: consensus on the treatment for patients with autoimmune pancreatitis in Japan. J Gastroenterol 2007, 42(Suppl.18):50-58.
134. Khan M.L., Colby T.V., Viggiano R.W., Fonseca R. Treatment with bortezomib of a patient having hyper IgG4disease. Clin Lymphoma Myeloma Leuk 2010, 10:217-219.
135. Topazian M., Witzig T.E., Smyrk T.C., Pulido J.S., Levy M.J., Kamath P.S., et al. Rituximab therapy for refractory biliary strictures in immunoglobulin G4-associated cholangitis. Clin Gastroenterol Hepatol 2008, 6:364-366.
136. Kamisawa T., Okamoto A. Autoimmune pancreatitis: proposal of IgG4-related sclerosing disease. J Gastroenterol 2006, 41:613-625.
137. Kitagawa S., Zen Y., Harada K., Sasaki M., Sato Y., Minato H., et al. Abundant IgG4-positive plasma cell infiltration characterizes chronic sclerosing sialadenitis (Kuttner's tumor). Am J Surg Pathol 2005, 29:783-791.