메뉴 건너뛰기




Volumn 129, Issue 12, 2011, Pages 2787-2796

Bfl-1 is a crucial pro-survival nuclear factor-κB target gene in Hodgkin/Reed-Sternberg cells

Author keywords

apoptosis; Bfl 1; Hodgkin's lymphoma

Indexed keywords

BCL2 RELATED PROTEIN A1; DNA; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SYNAPTOTAGMIN I; BCL2-RELATED PROTEIN A1; PROTEIN BCL 2;

EID: 84855170500     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25950     Document Type: Article
Times cited : (2)

References (49)
  • 1
    • 0029952779 scopus 로고    scopus 로고
    • Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells
    • DOI 10.1084/jem.184.4.1495
    • Kanzler H, Kuppers R, Hansmann ML, Rajewsky K,. Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. J Exp Med 1996; 184: 1495-505. (Pubitemid 26354704)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.4 , pp. 1495-1505
    • Kanzler, H.1    Kuppers, R.2    Hansmann, M.-L.3    Rajewsky, K.4
  • 2
    • 0028007479 scopus 로고
    • Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development
    • Kuppers R, Rajewsky K, Zhao M, Simons G, Laumann R, Fischer R, Hansmann M,. Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development. Proc Natl Acad Sci USA 1994; 91: 10962-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10962-10966
    • Kuppers, R.1    Rajewsky, K.2    Zhao, M.3    Simons, G.4    Laumann, R.5    Fischer, R.6    Hansmann, M.7
  • 3
    • 0036189576 scopus 로고    scopus 로고
    • Molecular biology of Hodgkin's lymphoma
    • DOI 10.1016/S0065-230X(02)84009-X
    • Kuppers R,. Molecular biology of Hodgkin's lymphoma. Adv Cancer Res 2002; 84: 277-312. (Pubitemid 34188200)
    • (2002) Advances in Cancer Research , vol.84 , pp. 277-312
    • Kuppers, R.1
  • 4
    • 0031919997 scopus 로고    scopus 로고
    • The origin of Hodgkin and Reed/Sternberg cells in Hodgkin's disease
    • DOI 10.1146/annurev.immunol.16.1.471
    • Kuppers R, Rajewsky K,. The origin of Hodgkin and Reed/Sternberg cells in Hodgkin's disease. Annu Rev Immunol 1998; 16: 471-93. (Pubitemid 28183373)
    • (1998) Annual Review of Immunology , vol.16 , pp. 471-493
    • Kuppers, R.1    Rajewsky, K.2
  • 5
    • 0037409887 scopus 로고    scopus 로고
    • Nuclear transcription factor-kappaB in Hodgkin's disease
    • DOI 10.1080/1042819031000067558
    • Younes A, Garg A, Aggarwal BB,. Nuclear transcription factor-kappaB in Hodgkin's disease. Leuk Lymphoma 2003; 44: 929-35. (Pubitemid 36416988)
    • (2003) Leukemia and Lymphoma , vol.44 , Issue.6 , pp. 929-935
    • Younes, A.1    Garg, A.2    Aggarwal, B.B.3
  • 6
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-κB and IKK function
    • DOI 10.1038/nrm2083, PII NRM2083
    • Perkins ND,. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 2007; 8: 49-62. (Pubitemid 46012014)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.1 , pp. 49-62
    • Perkins, N.D.1
  • 12
    • 34748924281 scopus 로고    scopus 로고
    • Bcl-2-regulated apoptosis: mechanism and therapeutic potential
    • DOI 10.1016/j.coi.2007.05.004, PII S0952791507000994, Hematopoietic cell death/Immunogenetics/Transplantation
    • Adams JM, Cory S,. Bcl-2-regulated apoptosis: mechanism and therapeutic potential. Curr Opin Immunol 2007; 19: 488-96. (Pubitemid 47487452)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.5 , pp. 488-496
    • Adams, J.M.1    Cory, S.2
  • 13
    • 26444558130 scopus 로고    scopus 로고
    • Pharmacological manipulation of Bcl-2 family members to control cell death
    • DOI 10.1172/JCI26250
    • Letai A,. Pharmacological manipulation of Bcl-2 family members to control cell death. J Clin Invest 2005; 115: 2648-55. (Pubitemid 41434388)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2648-2655
    • Letai, A.1
  • 14
    • 27544446991 scopus 로고    scopus 로고
    • Life in the balance: How BH3-only proteins induce apoptosis
    • DOI 10.1016/j.ceb.2005.10.001, PII S095506740500150X
    • Willis SN, Adams JM,. Life in the balance: how BH3-only proteins induce apoptosis. Curr Opin Cell Biol 2005; 17: 617-25. (Pubitemid 41540411)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.6 , pp. 617-625
    • Willis, S.N.1    Adams, J.M.2
  • 15
    • 0035324928 scopus 로고    scopus 로고
    • Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells
    • Hinz M, Loser P, Mathas S, Krappmann D, Dorken B, Scheidereit C,. Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells. Blood 2001; 97: 2798-807.
    • (2001) Blood , vol.97 , pp. 2798-2807
    • Hinz, M.1    Loser, P.2    Mathas, S.3    Krappmann, D.4    Dorken, B.5    Scheidereit, C.6
  • 16
    • 10744221518 scopus 로고    scopus 로고
    • Nuclear Factor κB-Dependent Activation of the Antiapoptotic bfl-1 Gene by the Epstein-Barr Virus Latent Membrane Protein 1 and Activated CD40 Receptor
    • DOI 10.1128/JVI.78.4.1800-1816.2004
    • D'souza BN, Edelstein LC, Pegman PM, Smith SM, Loughran ST, Clarke A, Mehl A, Rowe M, Gelinas C, Walls D,. Nuclear factor kappa B-dependent activation of the antiapoptotic bfl-1 gene by the Epstein-Barr virus latent membrane protein 1 and activated CD40 receptor. J Virol 2004; 78: 1800-16. (Pubitemid 38176712)
    • (2004) Journal of Virology , vol.78 , Issue.4 , pp. 1800-1816
    • D'Souza, B.N.1    Edelstein, L.C.2    Pegman, P.M.3    Smith, S.M.4    Loughran, S.T.5    Clarke, A.6    Mehl, A.7    Rowe, M.8    Gelinas, C.9    Walls, D.10
  • 17
    • 0033557805 scopus 로고    scopus 로고
    • Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
    • Grumont RJ, Rourke IJ, Gerondakis S,. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev 1999; 13: 400-11. (Pubitemid 29108756)
    • (1999) Genes and Development , vol.13 , Issue.4 , pp. 400-411
    • Grumont, R.J.1    Rourke, I.J.2    Gerondakis, S.3
  • 18
    • 0032588317 scopus 로고    scopus 로고
    • NF-κb induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
    • Wang CY, Guttridge DC, Mayo MW, Baldwin AS Jr., NF-kappaB induces expression of the bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol Cell Biol 1999; 19: 5923-9. (Pubitemid 29399297)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.9 , pp. 5923-5929
    • Wang, C.-Y.1    Guttridge, D.C.2    Mayo, M.W.3    Baldwin Jr., A.S.4
  • 19
    • 0033558215 scopus 로고    scopus 로고
    • The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis
    • Zong WX, Edelstein LC, Chen C, Bash J, Gelinas C,. The prosurvival bcl-2 homolog bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis. Genes Dev 1999; 13: 382-7. (Pubitemid 29108753)
    • (1999) Genes and Development , vol.13 , Issue.4 , pp. 382-387
    • Zong, W.-X.1    Edelstein, L.C.2    Chen, C.3    Bash, J.4    Gelinas, C.5
  • 20
    • 0033529416 scopus 로고    scopus 로고
    • NF-kappaB-mediated up-regulation of bcl-x and bfl-1/A1 is required for CD40 survival signaling in B lymphocytes
    • Lee HH, Dadgostar H, Cheng Q, Shu J, Cheng G,. NF-kappaB-mediated up-regulation of bcl-x and bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. Proc Natl Acad Sci USA 1999 Aug 3; 96 (16): 9136-41.
    • Proc Natl Acad Sci USA 1999 Aug 3 , vol.96 , Issue.16 , pp. 9136-9141
    • Lee, H.H.1    Dadgostar, H.2    Cheng, Q.3    Shu, J.4    Cheng, G.5
  • 23
    • 0036069776 scopus 로고    scopus 로고
    • Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease
    • DOI 10.1046/j.1365-2141.2002.03575.x
    • Reynolds GM, Billingham LJ, Gray LJ, Flavell JR, Najafipour S, Crocker J, Nelson P, Young LS, Murray PG,. Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease. Br J Haematol 2002; 118: 195-201. (Pubitemid 34779537)
    • (2002) British Journal of Haematology , vol.118 , Issue.1 , pp. 195-201
    • Reynolds, G.M.1    Billingham, L.J.2    Gray, L.J.3    Flavell, J.R.4    Najafipour, S.5    Crocker, J.6    Nelson, P.7    Young, L.S.8    Murray, P.G.9
  • 25
    • 34548161868 scopus 로고    scopus 로고
    • Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis
    • DOI 10.1038/sj.onc.1210363, PII 1210363
    • Brien G, Trescol-Biemont MC, Bonnefoy-Berard N,. Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis. Oncogene 2007; 26: 5828-32. (Pubitemid 47312815)
    • (2007) Oncogene , vol.26 , Issue.39 , pp. 5828-5832
    • Brien, G.1    Trescol-Biemont, M.-C.2    Bonnefoy-Berard, N.3
  • 27
    • 0029815941 scopus 로고    scopus 로고
    • Bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity
    • D'Sa-Eipper C, Subramanian T, Chinnadurai G,. Bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity. Cancer Res 1996; 56: 3879-82. (Pubitemid 26284731)
    • (1996) Cancer Research , vol.56 , Issue.17 , pp. 3879-3882
    • D'Sa-Eipper, C.1    Subramanian, T.2    Chinnadurai, G.3
  • 28
    • 13144249134 scopus 로고    scopus 로고
    • Expression of Bfl-1 in normal and tumor tissues: Bfl-1 overexpression in cancer is attributable to its preferential expression in infiltrating inflammatory cells
    • DOI 10.1016/S0046-8177(98)90282-9
    • Jung-Ha H, Kim D, Lee SB, Hong SI, Park SY, Huh J, Kim CW, Kim SS, Lee Y, Choi SS, Shin HS,. Expression of bfl-1 in normal and tumor tissues: Bfl-1 overexpression in cancer is attributable to its preferential expression in infiltrating inflammatory cells. Hum Pathol 1998; 29: 723-8. (Pubitemid 28322058)
    • (1998) Human Pathology , vol.29 , Issue.7 , pp. 723-728
    • Jung-Ha, H.1    Kim, D.2    Lee, S.-B.3    Hong, S.-I.4    Park, S.-Y.5    Huh, J.6    Kim, C.-W.7    Kim, S.-S.8    Lee, Y.9    Choi, S.S.10    Shin, H.-S.11
  • 29
    • 0033916788 scopus 로고    scopus 로고
    • The bfl-1 gene is transcriptionally upregulated by the Epstein-Barr virus LMP1, and its expression promotes the survival of a Burkitt's lymphoma cell line
    • DOI 10.1128/JVI.74.14.6652-6658.2000
    • D'Souza B, Rowe M, Walls D,. The bfl-1 gene is transcriptionally upregulated by the Epstein-Barr virus LMP1, and its expression promotes the survival of a Burkitt's lymphoma cell line. J Virol 2000; 74: 6652-8. (Pubitemid 30429836)
    • (2000) Journal of Virology , vol.74 , Issue.14 , pp. 6652-6658
    • D'Souza, B.1    Rowe, M.2    Walls, D.3
  • 30
    • 0037693201 scopus 로고    scopus 로고
    • Bfl-1S, a novel alternative splice variant of Bfl-1, localizes in the nucleus via its C-terminus and prevents cell death
    • DOI 10.1038/sj.onc.1206274
    • Ko JK, Lee MJ, Cho SH, Cho JA, Lee BY, Koh JS, Lee SS, Shim YH, Kim CW,. Bfl-1S, a novel alternative splice variant of bfl-1, localizes in the nucleus via its C-terminus and prevents cell death. Oncogene 2003; 22: 2457-65. (Pubitemid 36560729)
    • (2003) Oncogene , vol.22 , Issue.16 , pp. 2457-2465
    • Ko, J.-K.1    Lee, M.-J.2    Cho, S.-H.3    Cho, J.-A.4    Lee, B.-Y.5    Koh, J.S.6    Lee, S.-S.7    Shim, Y.-H.8    Kim, C.-W.9
  • 31
    • 0034287445 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells
    • Keller SA, Schattner EJ, Cesarman E,. Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells. Blood 2000; 96: 2537-42.
    • (2000) Blood , vol.96 , pp. 2537-2542
    • Keller, S.A.1    Schattner, E.J.2    Cesarman, E.3
  • 32
    • 0042744800 scopus 로고    scopus 로고
    • Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis
    • DOI 10.1182/blood-2002-04-1154
    • Mathas S, Lietz A, Janz M, Hinz M, Jundt F, Scheidereit C, Bommert K, Dorken B,. Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis. Blood 2003; 102: 1028-34. (Pubitemid 36917800)
    • (2003) Blood , vol.102 , Issue.3 , pp. 1028-1034
    • Mathas, S.1    Lietz, A.2    Janz, M.3    Hinz, M.4    Jundt, F.5    Scheidereit, C.6    Bommert, K.7    Dorken, B.8
  • 33
    • 0028986075 scopus 로고
    • Control of I-kappa-B-alpha proteolysis by site-specific, signal-induced phosphorylation
    • Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U,. Control of I-kappa-B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science 1995; 267: 1485-8.
    • (1995) Science , vol.267 , pp. 1485-1488
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 34
    • 0037384877 scopus 로고    scopus 로고
    • NF-κB-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bfl-1/A1
    • DOI 10.1128/MCB.23.8.2749-2761.2003
    • Edelstein LC, Lagos L, Simmons M, Tirumalai H, Gelinas C,. NF-kappa B-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor bfl-1/A1. Mol Cell Biol 2003; 23: 2749-61. (Pubitemid 36403075)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.8 , pp. 2749-2761
    • Edelstein, L.C.1    Lagos, L.2    Simmons, M.3    Tirumalai, H.4    Gelinas, C.5
  • 35
    • 1642565096 scopus 로고    scopus 로고
    • Expression of Bcl-2 family members and presence of Epstein-Barr virus in the regulation of cell growth and death in classical Hodgkin's lymphoma
    • DOI 10.1111/j.0309-0167.2004.01829.x
    • Kim LH, Nadarajah VS, Peh SC, Poppema S,. Expression of bcl-2 family members and presence of Epstein-Barr virus in the regulation of cell growth and death in classical Hodgkin's lymphoma. Histopathology 2004; 44: 257-67. (Pubitemid 38406619)
    • (2004) Histopathology , vol.44 , Issue.3 , pp. 257-267
    • Kim, L.-H.1    Nadarajah, V.S.2    Peh, S.-C.3    Poppema, S.4
  • 36
    • 33845312333 scopus 로고    scopus 로고
    • Expression of bcl2 family proteins and active caspase 3 in classical Hodgkin's lymphomas
    • DOI 10.1016/j.humpath.2006.06.017, PII S0046817706003819
    • Bai M, Papoudou-Bai A, Horianopoulos N, Grepi C, Agnantis NJ, Kanavaros P,. Expression of bcl2 family proteins and active caspase 3 in classical Hodgkin's lymphomas. Hum Pathol 2007; 38: 103-13. (Pubitemid 44880206)
    • (2007) Human Pathology , vol.38 , Issue.1 , pp. 103-113
    • Bai, M.1    Papoudou-Bai, A.2    Horianopoulos, N.3    Grepi, C.4    Agnantis, N.J.5    Kanavaros, P.6
  • 37
    • 0037097818 scopus 로고    scopus 로고
    • The role of cytokines in classical Hodgkin lymphoma
    • DOI 10.1182/blood-2002-01-0099
    • Skinnider BF, Mak TW,. The role of cytokines in classical Hodgkin's lymphoma. Blood 2002; 99: 4283-97. (Pubitemid 34627193)
    • (2002) Blood , vol.99 , Issue.12 , pp. 4283-4297
    • Skinnider, B.F.1    Mak, T.W.2
  • 38
    • 18744391362 scopus 로고    scopus 로고
    • An unbalanced translocation involving chromosome 14 is the probable cause for loss of potentially functional rearranged immunoglobulin heavy chain genes in the Epstein-Barr virus-positive Hodgkin's lymphoma-derived cell line L591
    • DOI 10.1046/j.1365-2141.2002.03894.x
    • Vockerodt M, Belge G, Kube D, Irsch J, Siebert R, Tesch H, Diehl V, Wolf J, Bullerdiek J, Staratschek-Jox A,. An unbalanced translocation involving chromosome 14 is the probable cause for loss of potentially functional rearranged immunoglobulin heavy chain genes in the Epstein-Barr virus-positive Hodgkin's lymphoma-derived cell line L591. Br J Haematol 2002; 119: 640-6. (Pubitemid 35366202)
    • (2002) British Journal of Haematology , vol.119 , Issue.3 , pp. 640-646
    • Vockerodt, M.1    Belge, G.2    Kube, D.3    Irsch, J.4    Siebert, R.5    Tesch, H.6    Diehl, V.7    Wolf, J.8    Bullerdiek, J.9    Staratschek-Jox, A.10
  • 40
    • 0033587084 scopus 로고    scopus 로고
    • Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IκBα
    • DOI 10.1038/sj.onc.1202893
    • Cabannes E, Khan G, Aillet F, Jarrett RF, Hay RT,. Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha. Oncogene 1999; 18: 3063-70. (Pubitemid 29261226)
    • (1999) Oncogene , vol.18 , Issue.20 , pp. 3063-3070
    • Cabannes, E.1    Khan, G.2    Aillet, F.3    Jarrett, R.F.4    Hay, R.T.5
  • 42
    • 34247353698 scopus 로고    scopus 로고
    • NF-κB-independent down-regulation of XIAP by bortezomib sensitizes HL B cells against cytotoxic drugs
    • DOI 10.1182/blood-2006-10-053959
    • Kashkar H, Deggerich A, Seeger JM, Yazdanpanah B, Wiegmann K, Haubert D, Pongratz C, Kronke M,. NF-kappaB-independent down-regulation of XIAP by bortezomib sensitizes HL B cells against cytotoxic drugs. Blood 2007; 109: 3982-8. (Pubitemid 46641751)
    • (2007) Blood , vol.109 , Issue.9 , pp. 3982-3988
    • Kashkar, H.1    Deggerich, A.2    Seeger, J.-M.3    Yazdanpanah, B.4    Wiegmann, K.5    Haubert, D.6    Pongratz, C.7    Kronke, M.8
  • 43
    • 28144441981 scopus 로고    scopus 로고
    • Inhibition of nuclear translocation of nuclear factor-κB despite lack of functional IκBα protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies
    • DOI 10.1158/1078-0432.CCR-05-0224
    • Thomas RK, Sos ML, Zander T, Mani O, Popov A, Berenbrinker D, Smola-Hess S, Schultze JL, Wolf J,. Inhibition of nuclear translocation of nuclear factor-kappa B despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies. Clin Cancer Res 2005; 11: 8186-94. (Pubitemid 41698763)
    • (2005) Clinical Cancer Research , vol.11 , Issue.22 , pp. 8186-8194
    • Thomas, R.K.1    Sos, M.L.2    Zander, T.3    Mani, O.4    Popov, A.5    Berenbrinker, D.6    Smola-Hess, S.7    Schultze, J.L.8    Wolf, J.9
  • 44
    • 0029861518 scopus 로고    scopus 로고
    • Endothelial cell death induced by tumor necrosis factor-α is inhibited by the Bcl-2 family member, A1
    • DOI 10.1074/jbc.271.44.27201
    • Karsan A, Yee E, Harlan JM,. Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the bcl-2 family member, A1. J Biol Chem 1996; 271: 27201-4. (Pubitemid 26367264)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.44 , pp. 27201-27204
    • Karsan, A.1    Yee, E.2    Harlan, J.M.3
  • 45
    • 11944251279 scopus 로고    scopus 로고
    • High expression of bfl-1 contributes to the apoptosis resistant phenotype in B-cell chronic lymphocytic leukemia
    • DOI 10.1002/ijc.20614
    • Morales AA, Olsson A, Celsing F, Osterborg A, Jondal M, Osorio LM,. High expression of bfl-1 contributes to the apoptosis resistant phenotype in B-cell chronic lymphocytic leukemia. Int J Cancer 2005; 113: 730-7. (Pubitemid 40101253)
    • (2005) International Journal of Cancer , vol.113 , Issue.5 , pp. 730-737
    • Morales, A.A.1    Olsson, A.2    Celsing, F.3    Osterborg, A.4    Jondal, M.5    Osorio, L.M.6
  • 47
    • 0038206722 scopus 로고    scopus 로고
    • Inhibition of constitutive NF-κB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
    • Pham LV, Tamayo AT, Yoshimura LC, Lo P, Ford RJ,. Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. J Immunol 2003; 171: 88-95. (Pubitemid 36745276)
    • (2003) Journal of Immunology , vol.171 , Issue.1 , pp. 88-95
    • Pham, L.V.1    Tamayo, A.T.2    Yoshimura, L.C.3    Lo, P.4    Ford, R.J.5
  • 48
    • 1842425016 scopus 로고    scopus 로고
    • Nuclear Factor-KappaB Modulation As a Therapeutic Approach in Hematologic Malignancies
    • DOI 10.1002/cncr.20182
    • Panwalkar A, Verstovsek S, Giles F,. Nuclear factor-kappaB modulation as a therapeutic approach in hematologic malignancies. Cancer 2004; 100: 1578-89. (Pubitemid 38456332)
    • (2004) Cancer , vol.100 , Issue.8 , pp. 1578-1589
    • Panwalkar, A.1    Verstovsek, S.2    Giles, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.