Effect of back pressure on emulsification of lipid nanodispersions in a high-pressure homogenizer

International Journal of Pharmaceutics

Volumn 422, Issue 1-2, 2012, Pages 489-494

  Saheki, Akira ^a,b   Seki, Junzo ^a   Nakanishi, Takeo ^b   Tamai, Ikumi ^b  

^a NIPPON SHINYAKU CO LTD   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Back pressure; Emulsion; High pressure homogenizer; Lipid nanodispersion; Liposome; Particle size

Indexed keywords

LIPID; LIPOSOME;

ARTICLE; BACK PRESSURE; DISPERSION; EMULSION; HEAT STRESS; HUMIDITY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRESSURE; PRIORITY JOURNAL; THERMOSTABILITY;

CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; EMULSIONS; EQUIPMENT DESIGN; LECITHINS; LIPOSOMES; NANOPARTICLES; NANOTECHNOLOGY; PARTICLE SIZE; PRESSURE; SOYBEAN OIL; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; TIME FACTORS;

EID: 84655176708     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.10.060     Document Type: Article

References (33)

1. N. Anton, J.P. Benoit, and P. Saulnier Design and production of nanoparticles formulated from nano-emulsion templates - a review J. Control. Release 128 2008 185 199
2. K. Arii, Y. Fukuta, T. Kai, and Y. Kokuba Preparation of fine emulsified fat particles without glycerol for intravenous nutrition Eur. J. Pharm. Sci. 9 1999 67 73 (Pubitemid 29430194)
3. D. Bachmann, M. Brandl, and G. Gregoriadis Preparation of liposomes using a Mini-Lab 8.30 H high-pressure homogenizer Int. J. Pharm. 91 1993 69 74 (Pubitemid 23121402)
4. R. Barnadas-Rodriguez, and M. Sabes Factors involved in the production of liposomes with a high-pressure homogenizer Int. J. Pharm. 213 2001 175 186 (Pubitemid 32119473)
5. M. Brandl, D. Bachmann, M. Drechsler, and K.H. Bauer Liposome preparation by a new high-pressure homogenizer Gaulin Micron LAB 40 Drug Dev. Ind. Pharm. 16 1990 2167 2191 (Pubitemid 20303064)
6. M. Brandl, M. Drechsler, D. Bachmann, C. Tardi, M. Schmidtgen, and K.H. Bauer Preparation and characterization of semi-solid phospholipid dispersions and dilutions thereof Int. J. Pharm. 170 1998 187 199 (Pubitemid 28473286)
7. M.L. Chen Lipid excipients and delivery systems for pharmaceutical development: a regulatory perspective Adv. Drug Deliv. Rev. 60 2008 768 777
8. P.P. Constantinides, M.V. Chaubal, and R. Shorr Advances in lipid nanodispersions for parenteral drug delivery and targeting Adv. Drug Deliv. Rev. 60 2008 757 767
9. CDER/FDA Draft Guideline for Industry, Liposome Drug Products, Chemistry; Manufacturing and Controls; Human Pharmacokinetics and Bioavailability; and Labeling Documentation 2002
10. H. Fukui, T. Koike, T. Nakagawa, A. Saheki, S. Sonoke, Y. Tomii, and J. Seki Comparison of LNS-AmB, a novel low-dose formulation of amphotericin B with Lipid Nano-Sphere (LNS®), with commercial lipid-based formulations Int. J. Pharm. 267 2003 101 112 (Pubitemid 37352954)
11. A. Gabizon, D.C. Price, J. Huberty, R.S. Bresalier, and D. Papahadjopoulos Effect of liposome composition and other factors on the targeting of liposomes to experimental tumors: biodistribution and imaging studies Cancer Res. 50 1990 6371 6378 (Pubitemid 20323703)
12. T. Handa, H. Saito, and K. Miyajima Phospholipid monolayers at the triolein-saline interface: production of microemulsion particles and conversion of monolayers to bilayers Biochemistry 29 1990 2884 2890 (Pubitemid 20122625)
13. G.A. Husseini, M.A. Diaz de la Rosa, E.S. Richardson, D.A. Christensen, and W.G. Pitt The role of cavitation in acoustically activated drug delivery J. Control. Release 107 2005 253 261 (Pubitemid 41316288)
14. D.D. Lasic Liposomes: From Physics to Applications vol. 523 1993 Elsevier Science B.V. Amsterdam pp. 77-78
15. S. Li, M.A. Rizzo, S. Bhattacharya, and L. Huang Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery Gene Ther. 5 1998 930 937 (Pubitemid 28371910)
16. D.C. Litzinger, A.M. Buiting, N. van Rooijen, and L. Huang Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes Biochim. Biophys. Acta 1190 1994 99 107 (Pubitemid 24066264)
17. D.C. Litzinger, J.M. Brown, I. Wala, S.A. Kaufman, G.Y. Han, C.L. Farrell, and D. Collins Fate of cationic liposomes and their complex with oligonucleotide in vivo Biochim. Biophys. Acta 1281 1996 139 149 (Pubitemid 26194106)
18. A. Nagayasu, K. Uchiyama, and H. Kiwada The size of liposome: a factor which affects their targeting efficiency to tumors and therapeutic activity of liposomal antitumor drugs Adv. Drug Deliv. Rev. 40 1999 75 87 (Pubitemid 29486605)
19. W.D. Pandolfe Development of the new gaulin Micro-gap™ homogenizing valve J. Dairy Sci. 65 1982 2035 2044
20. E.S. Richardson, W.G. Pitt, and D.J. Woodbury The role of cavitation in liposome formation Biophys. J. 93 2007 4100 4107 (Pubitemid 350294459)
21. J. Seki, S. Sonoke, A. Saheki, H. Fukui, H. Sasaki, and T. Mayumi A nanometer lipid emulsion, Lipid Nano-Sphere (LNS®), as a parenteral drug carrier for passive drug targeting Int. J. Pharm. 273 2004 75 83 (Pubitemid 38317042)
22. J. Seki, S. Sonoke, A. Saheki, H. Fukui, and T. Mayumi Decreased binding affinity of apolipoprotein E plays an important role in the reduced hepatic clearance of Lipid Nano-Sphere (LNS®) J. Drug Deliv. Sci. Technol. 14 2004 173 179 (Pubitemid 38797163)
23. S. Sonoke, T. Ueda, K. Fujiwara, Y. Sato, K. Takagaki, K. Hirabayashi, T. Ohgi, and J. Yano Tumor regression in mice by delivery of Bcl-2 small interfering RNA with pegylated cationic liposomes Cancer Res. 68 2008 8843 8851
24. B. Sternberg, K. Hong, W. Zheng, and D. Papahadjopoulos Ultrastructural characterization of cationic liposome-DNA complexes showing enhanced stability in serum and high transfection activity in vivo Biochim. Biophys. Acta 1375 1998 23 35 (Pubitemid 28511390)
25. H. Talsma, A.Y. Özer, L. Bloois, and D.J.A. Crommelin The size reduction of liposomes with a high-pressure homogenizer (Microfluidizer™). Characterization of prepared dispersions and comparisons with conventional methods Drug Dev. Ind. Pharm. 15 1989 197 207 (Pubitemid 19065553)
26. P. Taylor, and R.H. Ottewill The formation and ageing rates of oil-in water miniemulsions Colloids Surf. A: Physicochem. Eng. Aspects 88 1994 303 316
27. V.P. Torchilin Lipid-based parenteral drug delivery systems: biological implications K. Wasan, Role of Lipid Excipients in Modifying Oral and Parenteral Drug Delivery 2007 Wiley-Interscience Hoboken, New Jersey 48 87
28. S. Verma, Y. Lan, R. Gokhale, and D.J. Burgess Quality by design approach to understand the process of nanosuspension preparation Int. J. Pharm. 377 2009 185 198
29. C. Washington, and S.S. Davis The production of parenteral feeding emulsions by Microfluidizer Int. J. Pharm. 44 1988 169 176
30. C. Washington Stability of lipid emulsions for drug delivery Adv. Drug Deliv. Rev. 20 1996 131 145 (Pubitemid 26284153)
31. M.C. Woodle, and D.D. Lasic Sterically stabilized liposomes Biochim. Biophys. Acta 1113 1992 171 199
32. G. Wörle, M. Drechsler, M.H.J. Koch, B. Siekmann, K. Westesen, and H. Bunjes Influence of composition and preparation parameters on the properties of aqueous monoolein dispersions Int. J. Pharm. 329 2007 150 157 (Pubitemid 44940847)
33. X. Zhang, and L.E. Kirsch An assessment of techniques for evaluating the physical stability of parenteral emulsions PDA J. Pharm. Sci. Technol. 57 2003 300 315 (Pubitemid 37140054)