Preparation of fine emulsified fat particles without glycerol for intravenous nutrition

European Journal of Pharmaceutical Sciences

Volumn 9, Issue 1, 1999, Pages 67-73

  Arii, Kanji ^a   Fukuta, Yasuhiko ^a   Kai, Toshiya ^a   Kokuba, Yukifumi ^a  

^a Hoechst Marion Roussel L   (Japan)

Author keywords

Emulsion; Glycerol; Layer separation; Particle size

Indexed keywords

EMULSIFYING AGENT; GLYCEROL;

ARTICLE; CONTROLLED STUDY; EMULSION; INTRAVENOUS FEEDING; METHODOLOGY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; TEMPERATURE;

CHEMISTRY, PHARMACEUTICAL; FAT EMULSIONS, INTRAVENOUS; FATS; GLUCOSE; GLYCEROL; HUMANS; PARENTERAL NUTRITION; PARTICLE SIZE; PRESSURE; TEMPERATURE;

EID: 0032843078     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(99)00045-7     Document Type: Article

References (26)

1. Burnham W.R., Hansrani P.K., Knott C.E., Cook J.A., Davis S.S. Stability of a fat emulsion based intravenous feeding mixture. Int. J. Pharm. 13:1983;9-22.
2. Davis S.S. Pharmaceutical aspects of intravenous fat emulsions. J. Hosp. Pharm. 1:1974;149-171.
3. Driscoll D.F., Bhargava H.N., Li L., Zaim R.H., Babayan V.K., Bistrian B.R. Physicochemical stability of total nutrient admixtures. Am. J. Health Syst. Pharm. 52:1995;623-634.
4. Fukuta Y., Arii K., Matsuda A., Kokuba Y. Comparison of glucose and fat as energy sources in peripheral parenteral nutrition in rats. J. Nutr. Sci. Vitaminol. 44:1998;47-55.
5. Gulari E., Gulari E., Tsunashima Y., Chu B. Photon correlation spectroscopy of particle distributions. J. Chem. Phys. 70:1979;3965-3972.
6. Handa T., Saito H., Miyajima K. Phospholipid monolayers at the triolein-saline interface: Production of microemulsion particles and conversion of monolayers to bilayers. Biochemistry. 29:1990;2884-2890.
7. Iriyama K. The metabolic distinctiveness of emulsified lipid particles in the bloodstream and its clinical implications. Surg. Today. 26:1996;673-678.
8. Ishii F., Sasaki I., Ogata H. Effect of phospholipid emulsifiers on physicochemical properties of intravenous fat emulsions and/or drug carrier emulsions. J. Pharm. Pharmacol. 42:1990;513-515.
9. Kane K.F., Cologiovanni L., McKiernan J., Panos M.Z., Ayres R.C., Langman M.J., Lowes J.R. High osmolality feedings do not increase the incidence of thrombophlebitis during peripheral i.v. nutrition. J. Parenter. Enter. Nutr. 20:1996;194-197.
10. 1H-NMR. Chem. Pharm. Bull. 42:1994;1715-1719.
11. Komatsu H., Kitajima A., Okada S. Pharmaceutical characterization of commercially available intravenous fat emulsions: Estimation of average particle size, size distribution and surface potential using photon correlation spectroscopy. Chem. Pharm. Bull. 43:1995;1412-1415.
12. Li J., Caldwell K.D. Structural studies of commercial fat emulsions used in parenteral nutrition. J. Pharm. Sci. 83:1994;1586-1592.
13. Lutz O., Groves M.J. The effect of lysine, a water-structure breaker, on the stability of phospholipid-stabilized emulsions. J. Pharm. Pharmacol. 47:1995;566-570.
14. Magdassi S., Frank S.G. Formation of oil-in-glycerol/water emulsions. J. Dispos. Sci. Technol. 7:1986;599-612.
15. Magdassi S., Frank S.G. Formation of oil in glycerol/water emulsions: Effect of surfactant ethylene oxide content. J. Dispos. Sci. Technol. 11:1990;519-528.
16. Matsusue S., Nishimura S., Koizumi S., Nakamura T., Takeda H. Preventive effect of simultaneously infused lipid emulsion against thrombophlebitis during postoperative peripheral parenteral nutrition. Surg. Today. 25:1995;667-671.
17. Miller J.M., Coyle E.F., Sherman W.M., Hagberg J.M., Costill D.L., Fink W.J., Terblanche S.E., Holloszy J.O. Effect of glycerol feeding on endurance and metabolism during prolonged exercise in man. Med. Sci. Sports. Exerc. 15:1983;237-242.
18. Payne-James J.J., Khawaja H.T. First choice for total parenteral nutrition: The peripheral route. J. Parenter. Enter. Nutr. 17:1993;468-478.
19. Globule size distribution in intravenous emulsions. Pharmacopeial Forum. 20:1994;7170-7175.
20. Raucoules M., Ichai C., Sowka P., Grimaud D. Energy provision in parenteral nutrition. Ann. Fr. Anesth. Reanim. 11:1991;565-579.
21. Schott H., Royce A.E. Effect of inorganic additives on solutions of nonionic surfactants?: Emulsion stability. J. Pharm. Sci. 72:1983;1427-1436.
22. Schuberth O., Wretlind A. Intravenous infusion of fat emulsions, phosphatides and emulsifying agents. Acta Chir. Scand. 278:(Suppl.):1961;3-21.
23. Takamura A., Noro S., Minowa T., Koishi M. Evaluation of emulsion stability. The effect of a natural emulsifier, soya sterol, on w/o type emulsions. Chem. Pharm. Bull. 28:1980;696-701.
24. Washington C. The stability of intravenous fat emulsions in total parenteral nutrition mixtures. Int. J. Pharm. 66:1990;1-21.
25. Washington C., Athersuch A., Kynoch D.J. The electrokinetic properties of phospholipid stabilized fat emulsions.? The effect of glucose and of pH. Int. J. Pharm. 64:1990;217-222.
26. Yalabik-Kas H.S. Stability assessment of emulsion systems. STP Pharma. 1:1985;978-984.