Preparation and evaluation of immediate release ibuprofen solid dispersions using polyethylene glycol 4000

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 5, 2008, Pages 939-945

  Newa, Madhuri ^a   Bhandari, Krishna Hari ^a   Li, Dong Xun ^a   Kim, Jong Oh ^a   Yoo, Dong Sung ^a   Kim, Jung Ae ^a   Yoo, Bong Kyu ^a   Woo, Jong Soo ^a   Choi, Han Gon ^a   Yong, Chul Soon ^a  

^a Yeungnam University   (South Korea)

Author keywords

Bioavailability; Dissolution; Ibuprofen; Polyethylene glycol 4000; Solid dispersion; Solubility

Indexed keywords

IBUPROFEN; MACROGOL 4000;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG MIXTURE; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; INTESTINE MUCOSA PERMEABILITY; LOW TEMPERATURE PROCEDURES; MALE; MELTING POINT; NONHUMAN; RAT; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; EMULSIONS; EXCIPIENTS; IBUPROFEN; MALE; MICROSCOPY, ELECTRON, SCANNING; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES;

EID: 44349129780     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.939     Document Type: Article

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