Preliminary toxicokinetic study with different crystal forms of S (+)- ibuprofen (dexibuprofen) and R,S-lbuprofen in rats;Vorstudie zur toxikokinetic von S-(+)-ibuprofen(Dexibuprofen) und razemischen ibuprofen in unsterchiedlicher kristallform an der ratte

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 6, 1997, Pages 750-754

  Walser, Sabine ^a,e   Hruby, Robert ^b   Hesse, Ernst ^a   Heinzl, Harald ^c   Mascher, Hermann ^d  

^a Gebro Broschek GmbH   (Austria)

^b ARC SEIBERSDORF RESEARCH GMBH   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

^d Pharm Analyt Labor GmbH   (Austria)

^e PFIZER INC   (United States)

Author keywords

Anti inflammatories; CAS 15687 27 1; CAS 51146 56 6; Dexibuprofen; Non steroidal; R.S Ibuprofen, preclinical study, toxicokinetics; S (+) Ibuprofen

Indexed keywords

DEXIBUPROFEN; IBUPROFEN; IBUPROFEN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CRYSTAL; DRUG BLOOD LEVEL; DRUG SOLUBILITY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RACEMIC MIXTURE; RAT; TOXICOKINETICS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; CRYSTALLIZATION; CYCLOOXYGENASE INHIBITORS; GASTRIC JUICE; IBUPROFEN; INTESTINAL SECRETIONS; MALE; RATS; RATS, WISTAR; SOLUBILITY; STEREOISOMERISM;

EID: 0030792207     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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